NCT01342120

PHARMO Institute Seroquel Safety Study

Seroquel Safety Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 18,325 (actual)
• Sponsor: AstraZeneca · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this observational study is to study specific outcomes of interest in users of quetiapine compared with all other atypical antipsychotics and specifically olanzapine and risperidone. The outcomes of interest are all-cause mortality, failed suicide attempts, extrapyramidal symptoms, diabetes mellitus, hypothyroidism, acute myocardial infarction and stroke. This retrospective cohort study is based on population-based record linkage system (PHARMO RLS) capturing about 2.5 millions residents in the Netherlands.

Conditions

• Schizophrenia
• Major Depressive Disorder
• Bipolar Disorder
• Generalized Anxiety Disorder

Timeline

• Start date: 2010-09-01
• Primary completion: 2010-11-01
• Completion: 2010-11-01
• First posted: 2011-04-27
• Last updated: 2011-09-02