NCT03016052

Visual Mismatch Negativity in Attention Bias Modifcation Treatment for Anxiety

Visual Mismatch Negativity in Attention Bias Modifcation Treatment for Social and Generalized Anxiety- an ERP Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Tel Aviv University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

this study examines the emergence of the visual mismatch negativity (vMMN) ERP component in response to deviations from the embedded contingency in attention bias modification treatment (ABMT) for social and generalized anxiety, and the interaction between vMMN emergence and clinical improvement. \*\*\*As of September 2017, recruitment of SAD participants has concluded.

Detailed description

all participants, suffering from either social anxiety disorder or generalized anxiety disorder, will receive 6 sessions of ABMT, adapted for an oddball paradigm. two of the sessions will also include simultaneous EEG measurement. the goal of the study is to determine the emergence of vMMN in response to trials deviating the embedded contingency and to examine the correlation between vMMN emergence and clinical improvement of anxiety symptoms.

Conditions

• Social Anxiety Disorder
• Generalized Anxiety Disorder

Interventions

Type	Name	Description
BEHAVIORAL	ABMT	Participants will be trained with a dot-probe task including angry-neutral faces. The task will be adapted for the oddball paradigm, such that in 80% of trials the probe will appear in place of the neutral face, and in 20% of trials in place of the angry face.

Timeline

• Start date: 2016-05-01
• Primary completion: 2017-09-01
• Completion: 2017-10-01
• First posted: 2017-01-10
• Last updated: 2017-11-17

Locations

1 site across 1 country: Israel