| Not Yet Recruiting | The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens NCT02998502 | Johns Hopkins University | N/A |
| Not Yet Recruiting | Testing a Precision Psychotherapy System for Low-income Patients NCT05118594 | National Council of Scientific and Technical Research, Argentina | N/A |
| Recruiting | Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders NCT06661460 | Lund University | N/A |
| Not Yet Recruiting | Investigation of Pathogenic Gut Microbiota Patterns in Anxiety, Depression and Panic Disorders NCT07268729 | University of Toronto | — |
| Recruiting | Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings NCT06934525 | Bradley Hospital | N/A |
| Not Yet Recruiting | Psychoeducation Based on Acceptance and Commitment Therapy NCT06704399 | Muğla Sıtkı Koçman University | N/A |
| Recruiting | IL-33, sST2, and CRP in Panic Disorder NCT07444879 | Elazığ Mental Health and Diseases Hospital | — |
| Recruiting | Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children an NCT07024758 | Baylor College of Medicine | N/A |
| Recruiting | Stepped Versus Stratified Care for Anxiety Disorders in Youth NCT06942429 | Region Skane | N/A |
| Recruiting | Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method NCT07028216 | Georgetown University | N/A |
| Not Yet Recruiting | Investigations of Factors Associated With Treatment Response and Prognosis in Anxiety Disorders NCT06773585 | Kangbuk Samsung Hospital | — |
| Completed | α-N-acetylgalactosaminidase Levels in Panic Disorder NCT07424911 | Elazığ Mental Health and Diseases Hospital | — |
| Recruiting | Analyzing the Benefits of Using SYMPTOMS-JIT for in Vivo Exposure in Anxiety Disorders NCT06788119 | Universitat Jaume I | N/A |
| Completed | Epidemiological Study on the Prevalence of Mental Disorders in Slovakia NCT07129408 | Comenius University | — |
| Recruiting | LHC-CIDI-5 in Hong Kong NCT06804525 | The University of Hong Kong | — |
| Recruiting | Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4 NCT06563310 | University of Michigan | N/A |
| Recruiting | Qigong and Multicomponent Exercise in Panic Disorder NCT07439224 | Dokuz Eylul University | N/A |
| Completed | Self-Guided CBT Mobile App for Treatment-Resistant Panic Disorder (CBT) Cognitive Behavioral Therapy NCT07391943 | Universidade Federal do Rio de Janeiro | — |
| Recruiting | Efficacy and Safety of HB-1 for Panic Disorder NCT06483789 | Honeybrains Biotech LLC | Phase 2 |
| Completed | Neurobehavioral Correlates of Caffeine on Anxiety, Avoidance and Interoception in Healthy Individuals and Pani NCT06145490 | Uppsala University | N/A |
| Recruiting | The Effectiveness of Transdiagnostic CBT Protocol on Anxiety Disorders NCT06422728 | Ibn Haldun University | N/A |
| Completed | Neurofeedback Enhanced Cognitive Reappraisal Training NCT06132659 | University of Michigan | N/A |
| Not Yet Recruiting | Efficacy of Hydroxyzine for Patients With Panic Disorder NCT05737511 | Sultan Qaboos University | Phase 4 |
| Active Not Recruiting | Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder NCT05967468 | Baylor College of Medicine | N/A |
| Completed | A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder NCT05941442 | AbbVie | Phase 2 |
| Completed | Guided and Traditional Cognitive Behavioral Therapy Protocol for Resistant Panic NCT07247955 | Universidade Federal do Rio de Janeiro | N/A |
| Completed | Level of Physical Activity and Fear Learning NCT05203731 | NYU Langone Health | N/A |
| Recruiting | CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy NCT05467683 | University of Texas at Austin | N/A |
| Active Not Recruiting | Clinical Trial of a Group Self-management Support Program for Anxiety Disorders NCT05124639 | Université de Sherbrooke | N/A |
| Recruiting | Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety NCT05427708 | University of Texas at Austin | N/A |
| Completed | Clinical Markers of Panic and Generalized Anxiety Disorder NCT06071819 | University of Milano Bicocca | — |
| Completed | Effects of Caffeine on Anxiety, Emotional Processing, Approach-avoidance Behavior, and Interoception in Panic NCT05261594 | Uppsala University | N/A |
| Active Not Recruiting | Transdiagnostic Versus Diagnosis-specific Cognitive-behavioral Therapy NCT05249543 | Karolinska Institutet | N/A |
| Active Not Recruiting | Treatment of Anxiety Disorders With Trigeminal Nerve Stimulation NCT04931134 | Dr. Rafael Freire | N/A |
| Completed | Safety and Efficacy of HB-1 for Panic Disorder NCT05071430 | Honeybrains Biotech LLC | Phase 2 |
| Recruiting | Mindful Self-Compassion for Anxiety Disorders and Depression NCT05671419 | Georgetown University | N/A |
| Recruiting | Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral NCT05117255 | University of Minnesota | N/A |
| Completed | Relationship Between Repetitive Negative Thinking and CBT Outcomes NCT06370559 | South London and Maudsley NHS Foundation Trust | — |
| Active Not Recruiting | Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety NCT05157386 | Region Stockholm | — |
| Unknown | Cannabidiol for the Treatment of Anxiety Disorders: An 8-Week Pilot Study NCT03549819 | McMaster University | Phase 3 |
| Active Not Recruiting | Evaluating Clinical Routines for ICBT NCT05321628 | Karolinska Institutet | N/A |
| Recruiting | Effects and Cost-effectiveness of e-Meistring - a Guided Internet-delivered Psychological Treatment NCT05868135 | St. Olavs Hospital | — |
| Completed | Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder NCT04922502 | Baylor College of Medicine | N/A |
| Recruiting | Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicen NCT04900064 | Linnaeus University | N/A |
| Unknown | Xenon Inhalation for Treatment of Panic Disorder NCT04432155 | Nobilis Therapeutics Inc. | Phase 2 / Phase 3 |
| Withdrawn | Cannabinoids for the Treatment of Anxiety Disorders: An 8-Week Pilot Study NCT04569760 | McMaster University | Phase 3 |
| Terminated | The Relationship Between Panic Attack Symptoms and Atrial Fibrillation Episodes. NCT04634461 | State University of New York at Buffalo | — |
| Terminated | Cognitive Behavioral Therapy Group for Older Adults Delivered by Telethealth NCT04714164 | Nova Scotia Health Authority | N/A |
| Unknown | Development of Mental Health Outcomes Following the 2020 Petrinja Earthquake NCT04911933 | Neuropsychiatric Hospital dr Ivan Barbot | N/A |
| Completed | A Trial of the Effect of CVL-865 on Panic Symptoms Induced by Carbon Dioxide Inhalation in Healthy Subjects NCT04592536 | Cerevel Therapeutics, LLC | Phase 1 |
| Unknown | An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Person NCT05530642 | University of Regina | N/A |
| Completed | Mobile-assisted Case Management for Panic Disorder NCT05832905 | En Chu Kong Hospital | — |
| Unknown | Efficacy of an App-based CBT Featuring Virtual Reality for Anxiety Disorders NCT05510804 | Bartosz of Zurowski | N/A |
| Completed | Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing Problems NCT04179526 | Babes-Bolyai University | N/A |
| Unknown | Physical and Psychological Health Trajectories in the Context of Coronary Heart Disease NCT04433832 | Laval University | — |
| Completed | The Effect Of Transcranial Direct Current Stimulation In Panic Disorder NCT04160806 | Istanbul University | N/A |
| Unknown | Perinatal Mental Health Care in Switzerland NCT04185896 | Bern University of Applied Sciences | — |
| Completed | Investigations of Amygdala Function Using Neurophysiological Recording and Stimulation NCT03958903 | Stanford University | N/A |
| Recruiting | Risk and Resiliency Factors in the RCMP: A Prospective Investigation NCT05527509 | University of Regina | N/A |
| Completed | A 14 Week, Randomized, Placebo-Controlled Cross-Over Study of Methylphenidate Hydrochloride Controlled Release NCT03785223 | McMaster University | Phase 4 |
| Unknown | Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression NCT03899090 | Laureate Institute for Brain Research, Inc. | N/A |
| Unknown | Exosomal microRNAs as a Biomarker in Panic Disorder and in Response to CBT NCT04029740 | Hebrew University of Jerusalem | N/A |
| Unknown | RECOVERY: A Transdiagnostic Intervention for Anxiety and Depression NCT03917550 | West University of Timisoara | N/A |
| Unknown | Construction of a Questionnaire on Panic Disorder and Agoraphobia NCT03885453 | Ulrike Willutzki | — |
| Completed | Walking or High Intensity Exercise for Anxiety NCT03819426 | NYU Langone Health | N/A |
| Completed | A Validation Study of Mobile Virtual Reality-Based Self-Care and Exposure Therapy Contents for the Treatment o NCT04985019 | Gangnam Severance Hospital | N/A |
| Unknown | Measuring Physiology to Determine if Pre-panic Attack Detection is Possible NCT03360578 | Medical Psychology Center | — |
| Unknown | Improving Access to Child Anxiety Treatment NCT03528109 | Bradley Hospital | N/A |
| Completed | Treatments for Anxiety: Meditation and Escitalopram NCT03522844 | Georgetown University | Phase 4 |
| Completed | Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide NCT03925987 | Laureate Institute for Brain Research, Inc. | N/A |
| Completed | Adapting an Effective CBT for Comorbidity to a Computer-Delivered Format NCT03300232 | University of Minnesota | N/A |
| Completed | Bioequivalence Study of Paroxetine Tablets and Paxil® Under Fasting and Fed Conditions in Chinese Healthy Volu NCT03504475 | Beijing Tongren Hospital | Phase 1 |
| Unknown | Rumination Focus Cognitive Behavior Therapy NCT03507114 | West University of Timisoara | N/A |
| Recruiting | Neurobiological Markers of Treatment Response for Anxiety and OCD NCT05663489 | Haukeland University Hospital | — |
| Completed | Collabri Flex - Effect of Collaborative Care for People With Anxiety Disorders in General Practice NCT03113175 | Amager Hospital | N/A |
| Completed | Pragmatic Collaborative Care for Cardiac Inpatients With Depression or Anxiety NCT03118752 | Massachusetts General Hospital | N/A |
| Completed | The Association Between Physical Sensations and Thinking Styles NCT03233542 | Ruhr University of Bochum | N/A |
| Unknown | Neuroimaging of Pavlovian Fear Conditioning Processes in Patients With Pathological Anxiety NCT03498599 | University of Texas at Austin | N/A |
| Completed | The Modular Protocol for Mental Health (MPMH) NCT03143634 | Medical Research Council Cognition and Brain Sciences Unit | Phase 1 / Phase 2 |
| Completed | Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli NCT03206437 | Georgetown University | N/A |
| Unknown | Effectiveness & Cost-effectiveness of Internet-delivered Interventions for Depression and Anxiety Disorders in NCT03188575 | Silver Cloud Health | N/A |
| Completed | Improving Access to the Treatment of Anxiety and Depression Among Young Adults NCT03156556 | Universite de Moncton | N/A |
| Completed | CBT for Anxiety Sensitivity vs. Disorder-specific CBT: An RCT NCT03015285 | Nova Scotia Health Authority | N/A |
| Completed | Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety NCT02810171 | University of Michigan | N/A |
| Completed | Trans-diagnostic Group CBT vs. Standard Group CBT for Depression, Social Anxiety and Agoraphobia/Panic Disorde NCT02954731 | Psychiatric Research Unit, Region Zealand, Denmark | N/A |
| Completed | Examining the Effects of Reduced Environmental Stimulation on Anxiety NCT03051074 | Laureate Institute for Brain Research, Inc. | N/A |
| Completed | Attitudes of Professionals and the General Public in Israel Regarding ICBT NCT04659577 | Hebrew University of Jerusalem | N/A |
| Completed | Clinical Trial of Transdiagnostic Cognitive-Behavior Therapy for Anxiety Disorders NCT02811458 | Université de Sherbrooke | N/A |
| Completed | Transdiagnostic REBT Prevention Program for Adolescents NCT02756507 | Babes-Bolyai University | N/A |
| Completed | The Role of Orexin in Human Panic Disorder NCT02593682 | University of California, San Francisco | Phase 4 |
| Unknown | Internet-delivered Transdiagnostic Intervention for Anxiety and Depression NCT02739607 | West University of Timisoara | N/A |
| Unknown | Disruption of Memory Reconsolidating as a Treatment for Panic Disorder NCT02631694 | VU University of Amsterdam | Phase 2 |
| Completed | Integrated Mental Health Care and Vocational Rehabilitation to Individuals on Sick Leave Due to Anxiety and De NCT02872051 | Amager Hospital | N/A |
| Unknown | Threat-Avoidance Learning in Anxiety Patients NCT02336802 | KU Leuven | — |
| Unknown | Different Neural Circuit Mechanisms Between Cognitive Therapy and Behavior Therapy for Patients With Panic Dis NCT03199625 | Nanjing Medical University | Phase 2 |
| Completed | A Brief Version of Biofeedback Therapy for Panic Disorder NCT02826096 | National Taiwan University Hospital | N/A |
| Completed | Providing Tools for Effective Care and Treatment of Anxiety Disorders NCT02605668 | Technische Universität Dresden | N/A |
| Completed | Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa NCT02615119 | Laureate Institute for Brain Research, Inc. | N/A |
| Completed | Optimizing Exposure Therapy for Anxiety Disorders NCT04048824 | University of California, Los Angeles | N/A |
| Unknown | The Assessment and Treatment of Balance Impairment Using Virtual Reality (VR) in Panic Disorder Patients NCT01677429 | Sheba Medical Center | N/A |
| Unknown | Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis NCT02476136 | prof. Peter de Jonge | — |
| Completed | A 10-Week, Open-Label, Flexible Dose Adaptive Study Evaluating the Efficacy of Vortioxetine in Subjects With P NCT02395510 | Siyan Clinical Corporation | Phase 4 |
| Completed | Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders NCT01947647 | VA Office of Research and Development | N/A |
| Completed | Project Collabri for Treatment of Anxiety NCT02678624 | Amager Hospital | N/A |
| Completed | Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment NCT02305537 | Mclean Hospital | N/A |
| Completed | Transdiagnostic iCBT for Depression and Anxiety NCT02266693 | Centre for Addiction and Mental Health | N/A |
| Completed | Predictors and Moderators of Cognitive-Behavioral Therapy and Acceptance and Commitment Therapy for Panic Diso NCT05462184 | University of Alcala | N/A |
| Completed | ACT-smart: Smartphone-supplemented iCBT for Social Phobia and/or Panic Disorder NCT01963806 | Stockholm University | N/A |
| Completed | Using the Canary Breathing System for Panic Disorder Patients NCT01955954 | Palo Alto Health Sciences, Inc. | N/A |
| Completed | Internet-based Self-help Treatment for Panic Disorder: Two Ways of Complementary Psychological Support NCT02402322 | Universitat Autonoma de Barcelona | N/A |
| Unknown | Attention Retraining for Anxiety Disorder Patients Resistent to Antidepressants NCT01906268 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Effectiveness of Six Sessions CBT for Adolescents With Emotional Problems in Community Clinics NCT02150265 | University of Tromso | N/A |
| Terminated | D-cycloserine Augmented CBT for Panic Disorder NCT01680107 | University of Oxford | Phase 3 |
| Completed | Cortisol Evaluation in Abuse Survivors NCT01632553 | University of Bristol | — |
| Completed | Online Treatments for Mood and Anxiety Disorders in Primary Care NCT01482806 | University of Pittsburgh | Phase 2 / Phase 3 |
| Unknown | A Long-term Observational Study on the Efficacy of SSRIs or Combined Treatment(SSRIs+ CBT) in Panic Disorder P NCT01674673 | Samsung Medical Center | — |
| Completed | Escitalopram Trial for Irritable Bowel Syndrome (IBS) Patients With Panic Disorder NCT01551225 | Maastricht University Medical Center | Phase 4 |
| Completed | Efficacy and Mechanisms of Psychosocial Treatments for Panic Disorder NCT04366011 | Southern Methodist University | N/A |
| Unknown | Improving Access To Services to Community Based Outpatient Clinics (CBOC's) NCT01346241 | Michael E. DeBakey VA Medical Center | N/A |
| Completed | Physical Activity and Cognitive Behavioural Therapy in Panic Disorder and Agoraphobia NCT01928810 | Charite University, Berlin, Germany | N/A |
| Completed | Neural Effects of Cognitive-behaviour Therapy in Panic Disorder NCT03251235 | University of Oxford | N/A |
| Completed | A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients NCT01201967 | Massachusetts General Hospital | Phase 4 |
| Completed | False Safety Behavior Elimination Therapy: A Randomized Study of a Brief Individual Transdiagnostic Treatment NCT02082561 | Florida State University | N/A |
| Completed | LUCHAR - Latinos Using Counseling for Help With Asthma and Anxiety Reduction NCT01583296 | Albert Einstein College of Medicine | N/A |
| Completed | Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD) NCT01172652 | VA Palo Alto Health Care System | Phase 4 |
| Unknown | Mechanisms of Panic Disorders Treatment NCT01323556 | University Medicine Greifswald | Phase 2 / Phase 3 |
| Terminated | Treatment of Panic Disorder Via Internet With a Wireless Temperature Biofeedback Ring NCT01671033 | Chimei Medical Center | N/A |
| Active Not Recruiting | Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals NCT01075672 | Massachusetts General Hospital | N/A |
| Withdrawn | Investigation of Neuro-hormonal Mechanisms of Hunger, Fullness and Obesity. NCT01008371 | Medical University of South Carolina | — |
| Terminated | CO2 Inhalation and Risk for Panic Disorder NCT00930657 | National Institute of Mental Health (NIMH) | — |
| Completed | Physical Activity and Cognitive Behavioural Therapy in Panic Disorder NCT01788800 | Charite University, Berlin, Germany | N/A |
| Completed | Efficacy of Aerobic Exercise Added to Alprazolam in Panic Disorder Treatment NCT00803400 | University of Buenos Aires | Phase 4 |
| Completed | Virtual Reality Exposure Therapy in Agoraphobic Participants NCT00734370 | VU University of Amsterdam | N/A |
| Completed | Study of the Changes in Metabolic Parameters in Patients Treated With Escitalopram for Six Months NCT00711737 | Changi General Hospital | — |
| Completed | The Influence of the Menstrual Cycle on Lithium and Sertraline Blood Levels NCT01385709 | Weill Medical College of Cornell University | — |
| Terminated | Ramelteon for Sleep Initiation Insomnia in Individuals With Panic Disorder Who Are Also on Escitalopram for An NCT00746239 | Milton S. Hershey Medical Center | N/A |
| Terminated | Org 25935 Versus Placebo as Augmentation to Cognitive-behavioral Therapy to Treat Panic Disorder (P05705) NCT00725725 | Merck Sharp & Dohme LLC | Phase 2 |
| Terminated | Treatment of Panic Disorder Via Internet With a Wireless Temperature Biofeedback Ring NCT00825136 | Chimei Medical Center | N/A |
| Completed | Quetiapine in Co-Morbid Depressive and Anxiety Disorders NCT00688818 | Centre for Addiction and Mental Health | N/A |
| Completed | A Study Of Sertraline Compared With Paroxetine In The Treatment Of Panic Disorder NCT00677352 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 4 |
| Completed | Exposure, D-Cycloserine Enhancement, and Genetic Modulators in Panic Disorder NCT00790868 | Boston University Charles River Campus | Phase 2 |
| Completed | Treatment of Social Phobia and Panic Disorder in Adults NCT00619138 | Haukeland University Hospital | Phase 3 |
| Completed | Addressing Help-Seeking Barriers in Developing an Intensive Treatment for Veterans With Panic Disorder NCT00628979 | US Department of Veterans Affairs | N/A |
| Completed | Special Drug Use Investigation for PAXIL Tablet (Pediatric Panic Disorder) NCT01376128 | GlaxoSmithKline | — |
| Completed | A Study of Quetiapine SR (Seroquel SR) to Treat SSRI-Resistant, Comorbid Panic Disorder Patients NCT00619892 | Indiana University | Phase 4 |
| Completed | Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Panic Disorder With Comorbid Major Dep NCT00521352 | New York State Psychiatric Institute | Phase 2 |
| Completed | Neural Functioning Underlying Anxiety and Its Treatment (The INSULA Study) NCT00947570 | University of California, San Diego | N/A |
| Completed | Special Investigation Of Long Term Use Of Sertraline. NCT00605813 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | — |
| Completed | Evaluating the Effects of Stress in Pregnancy NCT00525226 | Emory University | — |
| Completed | Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and NCT00579280 | University of South Florida | Phase 4 |
| Completed | Evaluating the Relationship Between Tobacco Use, Anxiety Sensitivity, and Panic in Adolescents NCT00535964 | University of Arkansas, Fayetteville | — |
| Completed | Physical Exercise Versus Cognitive-behavioral Therapy (CBT) for Panic Disorders: A Randomised Controlled Trial NCT01076777 | University of Bergen | Phase 2 |
| Completed | Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse NCT00776685 | King's College London | Phase 2 / Phase 3 |
| Completed | Special Investigation Of J Zoloft For Panic Disorder Patients NCT00605917 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | — |
| Completed | Drug Use Investigation of Jzoloft. NCT00605865 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | — |
| Completed | Changes of Cerebral Glucose Metabolism and After 12 Weeks of Escitalpram Treatment in Panic Disorder NCT00767871 | Samsung Medical Center | Phase 4 |
| Completed | Changes of Cerebral Glucose Metabolism After 12 Weeks of Paroxetine Treatment in Panic Disorder NCT00767754 | Samsung Medical Center | Phase 4 |
| Completed | Study of Brain Circuitry in Anxiety Disorders NCT01849432 | Mclean Hospital | — |
| Completed | Comparison of Psychotherapy Programs to Treat Panic Disorder NCT00353470 | Weill Medical College of Cornell University | Phase 3 |
| Completed | The Efficacy and Tolerability of Duloxetine for the Treatment of Panic Disorder NCT00438971 | Massachusetts General Hospital | Phase 4 |
| Completed | Primary Care Intervention Strategy for Anxiety Disorders NCT00347269 | University of Washington | Phase 4 |
| Completed | Cognitive Behavior Psychotherapy in Panic Disorder NCT01025908 | Universidade Federal do Rio de Janeiro | N/A |
| Terminated | ELB139 Given Orally to Patients With Concurrent Panic Disorder, Challenged by CO2 Inhalation After a Single Do NCT00322803 | elbion AG | Phase 2 |
| Completed | Special Drug Use Investigation for PAXIL Tablet (Investigation in Case of Administered From 20mg/Day) NCT01371474 | GlaxoSmithKline | — |
| Completed | Cognitive Behavioral Therapy in Panic Disorder NCT00772746 | Universidade Federal do Rio de Janeiro | — |
| Completed | Treatment of Late-life Anxiety in Primary Care Settings NCT00938093 | Wake Forest University Health Sciences | N/A |
| Completed | Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety NCT00352469 | Creighton University | Phase 4 |
| Completed | Levetiracetam Treatment of Panic Disorder and Lactate-Induced Panic Attacks NCT00279617 | Lindner Center of HOPE | Phase 3 |
| Unknown | Genetic Abnormalities and Biological Changes of Panic Disorder Patients After Pharmacotherapy NCT00515996 | Samsung Medical Center | — |
| Completed | Trial to Compare Time to Response in the Symptoms of Anxiety to Concomitant Treatment With Niravam™ and an SSR NCT00266409 | UCB Pharma | Phase 4 |
| Unknown | Treatment of Panic Disorder Among Individuals Consulting Emergency Departments for Non Cardiac Chest Pain NCT00736346 | Université du Québec a Montréal | N/A |
| Completed | Aripiprazole for the Treatment of Refractory Anxiety NCT00438386 | Massachusetts General Hospital | Phase 4 |
| Completed | Breathing Regulation Training for Individuals With Panic Disorder NCT00183521 | Stanford University | N/A |
| Completed | Effectiveness of Intensive Cognitive Behavioral Therapy in Treating Adolescent Panic Disorder and Agoraphobia NCT00576719 | Boston University | Phase 2 |
| Completed | Neurobiological Mechanisms in Panic Disorder NCT00103987 | National Institute of Mental Health (NIMH) | — |
| Completed | Internet-Versus Group-Administered Cognitive Behavior Therapy for Panic Disorder NCT00845260 | Karolinska Institutet | Phase 3 |
| Completed | Augmenting Exposure Therapy With an N-Methyl-D-Aspartate (NMDA) Agonist for Panic Disorder NCT00131339 | Hartford Hospital | N/A |
| Completed | Evaluation of Substance P Neurotransmission in Panic Disorder by PET Imaging of NK1 Receptors With [18F]SPA-RQ NCT00088738 | National Institute of Mental Health (NIMH) | Phase 1 |
| Terminated | A Study to Assess the Long-term Use of Alprazolam Extended Release (XL) in the Treatment of Adolescents With P NCT00635076 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 4 |
| Completed | Genetic Causes of Panic Disorder NCT00083265 | National Institute of Mental Health (NIMH) | — |
| Terminated | A Study To Assess the Safety of Extended Release Alprazolam for the Treatment of Adolescents With Panic Disord NCT00634790 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 4 |
| Terminated | A Study to Evaluate the Use of Extended Release Alprazolam in the Treatment of Adolescents With Panic Disorder NCT00635531 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 4 |
| Completed | Levetiracetam for the Treatment of Alcohol Dependence and Anxiety NCT00141115 | New York State Psychiatric Institute | Phase 2 |
| Completed | Telephone-Based Care Management Program for Individuals With Anxiety Disorders NCT00158327 | University of Pittsburgh | Phase 3 |
| Unknown | Study of Virtual Reality Therapy and Cognitive Behavior Therapy in Panic Disorder With Agoraphobia NCT00129610 | Hospices Civils de Lyon | N/A |
| Completed | A Study of Sertraline and Early Alprazolam XR Administration Versus Sertraline Only in Panic Disorder Patients NCT00198094 | Indiana University School of Medicine | Phase 4 |
| Completed | Personality-targeted Interventions for Adolescent Alcohol Misuse NCT00344474 | King's College London | Phase 2 / Phase 3 |
| Completed | A Study of Risperidone Monotherapy in Bipolar Anxiety NCT00167479 | University of South Florida | Phase 4 |
| Completed | Efficacy of Treatment for Panic Disorder NCT00456768 | University of British Columbia | — |
| Terminated | Risperidone vs. Paroxetine for Panic Attacks NCT00206765 | Beth Israel Medical Center | Phase 2 |
| Completed | Therapy for Depression With Co-occurring Panic or Anxiety Symptoms NCT00051207 | University of Pittsburgh | Phase 1 / Phase 2 |
| Terminated | Sertraline in Generalized Social Phobia With Co-Occurring Anxiety and Mood Disorders NCT00182533 | Hamilton Health Sciences Corporation | Phase 4 |
| Completed | A Single-Blind Trial of Risperidone vs. Paroxetine for Treatment of Panic Attacks NCT00457106 | Beth Israel Medical Center | N/A |
| Unknown | Panic Disorder and Cardiac Risk NCT00168506 | Baker Heart Research Institute | N/A |
| Completed | Evaluation of Clonazepam and Paroxetine for Panic Disorder With Depression NCT00031317 | National Institute of Mental Health (NIMH) | Phase 4 |
| Completed | Interactive Computer Treatment for Panic Disorder NCT00063375 | Florida State University | Phase 1 |
| Completed | Ventilatory Physiology in Children at Risk for Anxiety NCT00101777 | National Institute of Mental Health (NIMH) | — |
| Completed | Study Evaluating Venlafaxine ER in Patients With Panic Disorder NCT00044772 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 3 |
| Completed | Brain Chemical Receptor Effects in Patients With Panic Disorder and Post-Traumatic Stress Disorder NCT00025974 | National Institute of Mental Health (NIMH) | — |
| Completed | Paroxetine vs Placebo Combined With Aerobic Exercise or Relaxation in Panic Disorder NCT00540098 | University of Göttingen | Phase 4 |
| Completed | Study Evaluating Venlafaxine ER in Adults With Panic Disorder NCT00038896 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 3 |
| Completed | Improving Quality of Primary Care for Patients With Anxiety and/or Panic Disorders NCT00102427 | University of Pittsburgh | Phase 2 / Phase 3 |
| Completed | Vestibular Dysfunction In Adult Patients With Panic Disorder With or Without Agoraphobia NCT00004367 | National Center for Research Resources (NCRR) | N/A |
| Completed | Psychodynamic Therapy for Treating Panic Disorder NCT00128388 | Weill Medical College of Cornell University | Phase 2 / Phase 3 |
| Completed | Long Term Treatment of Panic Disorder With Clonazepam or Paroxetine NCT02852577 | Universidade Federal do Rio de Janeiro | Phase 4 |
| Completed | Therapies for Treatment-Resistant Panic Disorder Symptoms NCT00118417 | Massachusetts General Hospital | Phase 2 / Phase 3 |
| Completed | Treatment of Panic Disorder: Long Term Strategies NCT00000368 | New York State Psychiatric Institute | Phase 3 |
| Completed | Effectiveness of Cognitive Behavioral Therapy With Panic Control Treatment for Adolescents With Panic Disorder NCT00705380 | Boston University | Phase 2 |
| Completed | Randomized Study of Cognitive-Behavioral Therapy vs Imipramine and Their Combination for Panic Disorder NCT00004834 | Northwell Health | N/A |
| Completed | Phase II Double-Blind, Placebo-Controlled Study of the Reinforcing Effects of Alprazolam in Patients With Anxi NCT00004373 | National Institute on Drug Abuse (NIDA) | Phase 2 |
| Completed | Pilot Study of Vestibular Rehabilitation Training for Panic Disorder With Vestibular Dysfunction NCT00004366 | National Center for Research Resources (NCRR) | N/A |
| Unknown | Costs of Lost Productive Time Among Korean Workers With Panic Disorder and Effect of Treatment With Paroxetine NCT00492414 | Inje University | Phase 4 |