Trials / Unknown
UnknownNCT02631694
Disruption of Memory Reconsolidating as a Treatment for Panic Disorder
Targeting Fear Memory by Disrupting the Process of Reconsolidating: A New Intervention for Panic Disorder
- Status
- Unknown
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- VU University of Amsterdam · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
Animal and human fear conditioning studies have repeatedly shown that administering propranolol before or after retrieval of a previously acquired fear results in an elimination of the fear expression. This approach, known as disruption of fear memory reconsolidation, is a promising new avenue for treating anxiety disorders. The present study aims to test its efficacy in patients with panic disorder.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Propranolol | Intake of propranolol pill (40 milligram) |
| DRUG | Placebo | Intake of placebo pill (40 milligram) |
| OTHER | Carbon dioxide | Inhalation of 35% carbon dioxide |
| OTHER | Compressed air | Inhalation of air |
Timeline
- Start date
- 2016-04-01
- Primary completion
- 2018-09-01
- Completion
- 2019-09-01
- First posted
- 2015-12-16
- Last updated
- 2015-12-16
Source: ClinicalTrials.gov record NCT02631694. Inclusion in this directory is not an endorsement.