Trials / Conditions / Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)

166 registered clinical trials studyying Major Depressive Disorder (MDD) — 89 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical Applicatio NCT07444463	Central South University	N/A
Not Yet Recruiting	A Study to Assess the Skin Irritation and Sensitization of Selegiline TDS in Healthy Subjects NCT07452692	Corium Innovations, Inc.	Phase 1
Not Yet Recruiting	Neuroimaging Markers of Midlife Depression and Cognitive Behavioural Therapy (CBT) NCT07091643	Baycrest	N/A
Not Yet Recruiting	Imaging- vs. Scalp-Targeted Accelerated TMS for Depression: The Number Needed to Scan Trial NCT07043738	Brigham and Women's Hospital	N/A
Not Yet Recruiting	Efficacy and Safety of a Theta Burst Stimulation Protocol of Repetitive Transcranial Magnetic Stimulation in T NCT07529574	Jung-Sun Lee	N/A
Not Yet Recruiting	Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal Thoughts NCT07139106	New York State Psychiatric Institute	Phase 4
Not Yet Recruiting	Investigating Functional Changes in the Frontotemporal Cortex of Patients With Major Depressive Disorder Follo NCT07533773	The Second Hospital of Anhui Medical University	N/A
Not Yet Recruiting	Evaluating Conversational Artificial Intelligence for Depression Management NCT07105397	George Mason University	N/A
Not Yet Recruiting	Pattern Separation in Major Depressive Disorder NCT07139834	Jeffrey Miller	Phase 1
Not Yet Recruiting	Efficacy of Spectrally Optimized Light on Cognitive Impairment in Major Depressive Disorder and Its Neuroimagi NCT07508215	Peking University Sixth Hospital	N/A
Recruiting	A Clinical Trial of Add-on Oral Slow-release Ketamine Treatment in Major Depression NCT07396272	Daniel Lindqvist	Phase 2
Not Yet Recruiting	Ketogenic Diet and Neuromodulation in Treatment Resistant Depression NCT07376018	Sunnybrook Health Sciences Centre	N/A
Not Yet Recruiting	Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder NCT07405606	Centre for Addiction and Mental Health	Phase 2
Enrolling By Invitation	Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a NCT07314190	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	—
Not Yet Recruiting	A Longitudinal Follow-Up Study on Predicting Major Depressive Disorder From Rest-Activity Rhythm Profiles NCT07388849	Chinese University of Hong Kong	—
Not Yet Recruiting	Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine NCT06788249	University of Pennsylvania	EARLY_Phase 1
Recruiting	Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder NCT07226661	Supernus Pharmaceuticals, Inc.	Phase 2
Enrolling By Invitation	Salivary Oxytocin as a Biomarker of Psychedelic Treatment NCT07345858	University of Geneva, Switzerland	—
Recruiting	Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant Depression NCT07324070	Charles University, Czech Republic	N/A
Not Yet Recruiting	Mechanisms Of Orbitofrontal Stimulation in Depression NCT07230990	Subha Subramanian	N/A
Not Yet Recruiting	Gaze Contingent Attentional Reinforcement in Major Depressive Disorder NCT07364981	Tel Aviv University	N/A
Enrolling By Invitation	Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers a NCT07239843	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	—
Recruiting	Home-Based tDCS for Depression in BPD NCT06972368	Ciusss de L'Est de l'Île de Montréal	N/A
Recruiting	A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression NCT07300969	Draig Therapeutics Ltd	Phase 2
Recruiting	Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression NCT06773949	The Royal Ottawa Mental Health Centre	N/A
Recruiting	Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements NCT07294924	Kernel	—
Recruiting	A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder NCT06793397	Cybin IRL Limited	Phase 3
Not Yet Recruiting	Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL) NCT07247370	South West Sydney Local Health District	Phase 1 / Phase 2
Recruiting	Dextromethorphan-Bupropion on Striatal Activity in Adults With Major Depressive Disorder NCT07523048	Roger McIntyre	Phase 2
Recruiting	Neurofeedback to Treat Depression - 2 NCT07159061	University of Pennsylvania	N/A
Recruiting	Home-Based Transcranial Direct Current Stimulation In Major Depressive Disorder (HOME) NCT07228468	King's College London	N/A
Recruiting	ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response NCT07284667	ACADIA Pharmaceuticals Inc.	Phase 2
Recruiting	Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation NCT07217444	Children's Hospital Medical Center, Cincinnati	N/A
Recruiting	Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Tre NCT07479758	Second Affiliated Hospital, School of Medicine, Zhejiang University	—
Not Yet Recruiting	Assessment of Whether Telehealth Family Psychoeducation for Major Depressive Disorder is Doable NCT07014241	University of Southern Queensland	N/A
Recruiting	Group Therapy for Major Depression: Comparing Expectation-Focused and Reward-Focused Psychotherapy Approaches NCT07388004	Philipps University Marburg	N/A
Recruiting	tVNS, Motivation, and Insulin Sensitivity NCT07198100	University of Bonn	N/A
Recruiting	Accelerated TMS for Treatment-Resistant ECT NCT07115628	Universitair Ziekenhuis Brussel	N/A
Recruiting	Lifestyle Interventions to Prevent Cognitive Deficits in Subjects With Depressive Symptoms: From Mechanisms to NCT07009223	IRCCS Centro San Giovanni di Dio Fatebenefratelli	N/A
Recruiting	NUTRIBRAIN: Lifestyle Interventions to Prevent cOgnitive Deficits in Subjects With Depressive Symptoms: From m NCT07462013	National Science and Technology Council, Taiwan	N/A
Recruiting	Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility an NCT07217223	University of California, San Diego	N/A
Not Yet Recruiting	Internet-Based Cognitive Behavioral Therapy With Treatment as Usual for Generalized Anxiety Disorder and Major NCT07177365	National Health Research Institutes, Taiwan	N/A
Enrolling By Invitation	An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants W NCT07161700	Seaport Therapeutics	Phase 2
Recruiting	Orexin Antagonism for Suicide Risk: A Proof-of-Concept Clinical Trial NCT06854224	Marianne Goodman	Phase 2
Recruiting	Physical Therapy for Depression Quality of Life (Pilot Study Protocol) NCT06983405	Universidad San Jorge	N/A
Not Yet Recruiting	Sedation and Guided Education for Depression Study NCT06705270	Stanford University	N/A
Recruiting	The Role of mGluR5 in CBT-I NCT07076342	Stony Brook University	Phase 4
Recruiting	Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Ca NCT07185815	Mapi Pharma Ltd.	Phase 1 / Phase 2
Not Yet Recruiting	A Phase 2 Study to Evaluate Efficacy and Safety of KH607 Tablets in Adult Participents With Major Depressive D NCT07101120	Chengdu Kanghong Pharmaceutical Group Co., Ltd.	Phase 2
Recruiting	Accelerated Neuromodulation of Anterior Cingulate Cortex for Depression NCT07212465	Rotman Research Institute at Baycrest	N/A
Completed	Study to Evaluate Efficacy and Safety of Ropanicant in MDD Patients NCT06836063	Suven Life Sciences Limited	Phase 2
Recruiting	Validation of EmoDTx as a Digital Endpoint for Mood Monitoring in Adult Patients Suffering From Unipolar Depre NCT06860165	Emobot	—
Completed	Magnesium Supplementation With Fluoxetine for Cognitive Function in Depression NCT07521358	Hasanuddin University	N/A
Recruiting	Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suici NCT07025720	University of California, Davis	N/A
Not Yet Recruiting	Implementation of a Multiple Intervention to Promote Healthy Lifestyles in Patients With Depression NCT06990035	IRCCS Centro San Giovanni di Dio Fatebenefratelli	N/A
Recruiting	Home-Based tDCS Treatment Of Major Depressive Disorder NCT06976697	Sooma Medical Inc	N/A
Not Yet Recruiting	Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression（SMART-I) NCT07011693	Xinyu Zhou	Phase 4
Recruiting	A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disor NCT07065240	Seaport Therapeutics	Phase 2
Recruiting	Moving on After Breast Cancer Trial for Depressed Breast Cancer Survivors in Pakistan NCT07015944	Pakistan Institute of Living and Learning	N/A
Recruiting	Gender Differences in Depression Severity, Gender-Sensitive Symptoms, Resilience, and Stigma in Major Depressi NCT07474363	Eskisehir Osmangazi University	—
Recruiting	Theta-Burst Stimulation to Treat Depression NCT07033780	Centre for Addiction and Mental Health	Phase 1
Recruiting	A Study to Evaluate the Efficacy, Safety, and Pharmacokinetic Characteristics of (R)-Ketamine Hydrochloride Na NCT07193901	Sichuan Purity Pharmaceutical Technology Co., Ltd.	Phase 2
Enrolling By Invitation	6 Weeks Right-Amygdala TIS for Depression NCT07059143	Ruijin Hospital	N/A
Recruiting	EEG-based Neurofeedback to Improve Emotion Regulation in Major Depressive Disorder: A Randomized Clinical Tria NCT07041073	Corporacion Parc Tauli	N/A
Active Not Recruiting	Neurobiological Mechanisms of Pathological Rumination and Effects of Aripiprazole NCT06937476	Central South University	N/A
Active Not Recruiting	Efficacy of Dextromethorphan-Bupropion Versus SSRIs in the Treatment of Major Depressive Disorder NCT06957223	Asad Ullah Jan	N/A
Active Not Recruiting	IWLS for Major Depressive Disorder: An Open-Label Study of Safety, Tolerability, and Efficacy NCT06922812	University of Sao Paulo	N/A
Active Not Recruiting	Physical Activity-based Intervention in Depressed Patients: Clinical, Neurophysiological, Epigenetic and Metab NCT06989944	IRCCS Centro San Giovanni di Dio Fatebenefratelli	N/A
Recruiting	Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits NCT06728774	Portland VA Medical Center	N/A
Recruiting	VR Pupillometry in Cognitive Impairment NCT07402356	Max-Planck-Institute of Psychiatry	—
Recruiting	A Trial of Dextromethorphan and Bupropion Sustained-Release Tablets in Patients With Major Depressive Disorder NCT06958692	CSPC Ouyi Pharmaceutical Co., Ltd.	Phase 3
Recruiting	Understanding and Treating Suicidal Ideation With Ketamine NCT06891300	The Royal's Institute of Mental Health Research	Phase 2 / Phase 3
Not Yet Recruiting	Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD) NCT06470035	Neurovalens Ltd.	N/A
Recruiting	Evaluation of the Concordance Between Measures Obtained by a Medical Device for Emotional Monitoring (EMOCARE) NCT06601140	Emobot	N/A
Recruiting	Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Dis NCT06830044	Vanda Pharmaceuticals	Phase 3
Not Yet Recruiting	Psilocybin Therapy for Psychological Distress in Palliative Patients NCT06782724	University Medical Center Groningen	Phase 2
Recruiting	Multimodal Phenotyping in Adolescent Inpatient Depression: An Observational Study NCT07247344	Jiangsu Province Nanjing Brain Hospital	—
Not Yet Recruiting	The Research of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression NCT06827431	CSPC ZhongQi Pharmaceutical Technology Co., Ltd.	Phase 3
Enrolling By Invitation	Understanding Mechanisms of Synaptic Degeneration Underlying Clinical Symptoms in Patients With MDs and NDs. NCT07234851	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	—
Not Yet Recruiting	Lemborexant for the Treatment of Residual Insomnia in Major Depressive Disorder (MDD) NCT06843187	Unity Health Toronto	Phase 2
Recruiting	LHC-CIDI-5 in Hong Kong NCT06804525	The University of Hong Kong	—
Completed	NQ TMS for MDD Therapy Using 1 Day x 3 Sessions Protocol for Adult Patient NCT06772987	NeuroQore Inc.	N/A
Active Not Recruiting	A Study of ONO-1110 in Patients With Major Depressive Disorder NCT06792136	Ono Pharmaceutical Co., Ltd.	Phase 2
Not Yet Recruiting	Non-invasive Brain Stimulation in Subjects with Major Depressive Disorder NCT06714643	Carmen Concerto	N/A
Recruiting	Neurobiological and Genomic Predictors of Relapse in Depression NCT07328373	Mehmet Kemal Arikan	—
Recruiting	Assessment of the Efficacy and Safety of Fecal Microbiota Transplantation (FMT) in Patients With Major Depress NCT06692361	Gang Wang	N/A
Withdrawn	A Study to Evaluate the Efficacy and Safety of REL-1017 As Adjunctive Treatment of Major Depressive Disorder ( NCT06735079	MGGM LLC	Phase 3
Not Yet Recruiting	A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Study on the Treatment of Depression with NCT06749470	Central South University	Phase 4
Recruiting	Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study NCT06732089	Unity Health Toronto	—
Completed	Stingless Bee Honey Augmentation in Major Depressive Disorders NCT06723249	Hospital Universiti Sains Malaysia	N/A
Recruiting	Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics NCT06624137	Yale University	—
Completed	A Phase II Study to Evaluate NH102 for Depression NCT06842992	Jiangsu Nhwa Pharmaceutical Co., Ltd.	Phase 2
Terminated	A Study to Assess Adverse Events of Fosigotifator (ABBV-CLS-7262) in Adults With Major Depressive Disorder NCT06618118	AbbVie	Phase 1
Completed	Efficacy and Safety Study of Levomilnacipran Hydrochloride Extended-Release Capsules in Major Depressive Disor NCT07253207	Zhejiang Huahai Pharmaceutical Co., Ltd.	Phase 3
Recruiting	Predictors of Relapse in Major Depressive Disorder NCT06746155	Abraham Nunes	—
Recruiting	PET Imaging Using the Tracer [18F]VAT to Assess the Antidepressant Effect of Nicotine. NCT07095205	Stony Brook University	Phase 4
Completed	Impact of Anxiety and Depression on Implicit and Explicit Memory Performance NCT06663423	Islamic Azad University, Sanandaj	—
Recruiting	Effectiveness of MST Versus ECT for Major Depressive Episode NCT06409325	Shanghai Mental Health Center	N/A
Enrolling By Invitation	Investigating the Brain's Physiological Responses in Depression and Autism, Using Transcranial Magnetic Stimul NCT06821646	National Taiwan University Hospital	—
Recruiting	Electroencephalography-based Precise Repetitive Transcranial Magnetic Stimulation Treatment NCT06385405	Shanghai Mental Health Center	N/A
Completed	Caregiver Depression in a Low-Resource Setting: Socio-Demographic Predictors of Major Depressive Disorder Amon NCT06992167	Rahmah Health Foundation	—
Recruiting	Psychoeducational Group for Depression NCT06467474	Ricardo Alberto Moreno, M.D., Ph.D.	N/A
Completed	Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders NCT07452835	Menoufia University	N/A
Active Not Recruiting	Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression NCT05966532	University of Texas Southwestern Medical Center	—
Unknown	A Study of HS-10353 in Adult Participants With Major Depressive Disorder NCT05938179	Jiangsu Hansoh Pharmaceutical Co., Ltd.	Phase 2
Completed	Predictors of rTMS and Group Therapy Efficacy in Adolescent Depression NCT07283419	The First Hospital of Hebei Medical University	—
Completed	Validation of Accexible as a Tool for Screening and Monitoring Depression. NCT06044818	Accexible	—
Recruiting	Influence of Nutrition in Depression Treatment (INDEPT) NCT05745194	Associacao para Investigacao e Desenvolvimento da Faculdade de Medicina - CETERA	N/A
Unknown	The Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression NCT05762458	CSPC ZhongQi Pharmaceutical Technology Co., Ltd.	Phase 2
Completed	The Effect of Transcranial Magnetic Stimulation Treatment on Microvasculature Stracture of the Retina and the NCT06708013	Gulhane Training and Research Hospital	N/A
Recruiting	Reward-specific Changes of the Chemical Messenger Dopamine in the Brain of Healthy and Depressed People NCT06675851	Medical University of Vienna	Phase 4
Completed	Single Dose Study to Evaluate Dose-proportionality of Vortioxetine Hemihydrobromide Orally Disintegrating Tabl NCT05416762	Seasons Biotechnology (Taizhou) Co., Ltd.	Phase 1
Completed	Food Effect Bioavailability Study of Vortioxetine Hemihydrobromide Orally Disintegrating Tablets NCT05416957	Seasons Biotechnology (Taizhou) Co., Ltd.	Phase 1
Withdrawn	Open-label Brexpiprazole fMRI Trial in Adults With Major Depressive Disorder and Anxiety NCT05504486	Otsuka Pharmaceutical Development & Commercialization, Inc.	Phase 4
Completed	A Study to Evaluate Efficacy and Safety of GW117 Tablets in Major Depressive Disorder NCT06796868	Beijing Greatway Pharmaceutical Technology Co.,Ltd.	Phase 2
Completed	Single Dose Oral Bioequivalence Study of Vortioxetine Hemihydrobromide Orally Disintegrating Tablets NCT05417087	Seasons Biotechnology (Taizhou) Co., Ltd.	Phase 1
Completed	Group Acceptance and Commitment Therapy (ACT) Among Depressive Patients in Kelantan, Malaysia NCT06710912	Universiti Sains Malaysia	N/A
Completed	Integral Cognitive Remediation for Depression NCT07014683	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	N/A
Unknown	Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression NCT05018013	CSPC ZhongQi Pharmaceutical Technology Co., Ltd.	Phase 2
Active Not Recruiting	Retrospective Observational Study of Intensity Effects in Psychedelic-assisted Treatment NCT07164287	University Hospital, Geneva	—
Completed	Effectiveness of Walking Exercise in Improving Depression in Older Adults With Major Depressive Disorder, A Pi NCT04403373	The University of Hong Kong	N/A
Active Not Recruiting	PRASED - Preventing Relapse After Successful Electroconvulsive Therapy for Depression NCT06751875	Universiteit Antwerpen	N/A
Suspended	A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease NCT04031469	ProgenaBiome	—
Completed	Efficacy of Clinical Application of Transcranial Low Intensity Focused Ultrasonic Stimulation for Patients Wit NCT04405791	Gangnam Severance Hospital	Phase 3
Completed	A Study to Evaluate the Efficacy and Safety of Ansofaxine Hydrochloride Extended-release Tablets in the Treatm NCT04853407	Luye Pharma Group Ltd.	Phase 3
Active Not Recruiting	A Study in Patients With Major Depressive Disorder NCT03642964	Chase Therapeutics Corporation	Phase 2
Unknown	Scopolamine in Healthy Volunteers NCT03874130	Repurposed Therapeutics, Inc.	Phase 1
Completed	Cognitive Effects Associated With Hippocampal Neurogenesis Induced by ECT in the Treatment of Depression NCT06661616	Centre Hospitalier St Anne	—
Unknown	Efficacy of H7-Coil DTMS Compared to H1-Coil DTMS in Subjects With Major Depression Disorder (MDD) NCT03012724	Brainsway	N/A
Completed	Comparison of Anyu Peibo With Placebo in Treatment of MDD NCT02380066	Shanghai Mental Health Center	Phase 2
Unknown	Comparison of Yuxintine With Placebo in Treatment of MDD NCT02395263	Shanghai Mental Health Center	Phase 2
Completed	Comparison of Orcinoside With Placebo in Treatment of MDD NCT02191384	Shanghai Mental Health Center	Phase 2
Completed	Genomics Used to Improve DEpression Decisions NCT02109939	Assurex Health Inc.	N/A
Unknown	Cardiovascular Effects of Agomelatine and Escitalopram in Patients With Major Depressive Disorder (MDD) NCT01483053	Baker Heart and Diabetes Institute	Phase 4
Completed	Brexpiprazole as Adjunctive Therapy With Major Depressive Disorder and an Inadequate Response to Previous Adju NCT02012218	Otsuka Pharmaceutical Development & Commercialization, Inc.	Phase 3
Completed	Add-On Study of MSI-195 (S-Adenosyl-L-Methionine, SAMe) for Patients With Major Depressive Disorder (MDD) NCT01912196	MSI Methylation Sciences, Inc.	Phase 2
Completed	An Investigation of Early Life Stress and Depression NCT01701258	Mclean Hospital	Phase 1
Completed	Improving Depression Outcome by Enhancing Memory for Cognitive Therapy NCT01790919	University of California, Berkeley	Phase 2
Completed	Switching From Generic Selective Serotonin Reuptake Inhibitors (SSRIs) and Selective Serotonin and Norepinephr NCT02015546	Duke University	Phase 3
Completed	European Drug Utilization Study NCT01594996	AstraZeneca	—
Completed	The Effects of Dopamine on Reward Processing NCT01253421	Mclean Hospital	Phase 1
Completed	Multimodal Assessment of Neurobiological Markers for Psychiatric Disorders NCT01477203	Medical University of Vienna	Phase 4
Completed	A Study of Flexible or Fixed Dose LY2216684 as Adjunctive Treatment for Participants With Major Depressive Dis NCT01187407	Eli Lilly and Company	Phase 3
Terminated	To Assess the Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants NCT01123707	Otsuka Pharmaceutical Development & Commercialization, Inc.	Phase 3
Terminated	Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Thera NCT01111565	Otsuka Pharmaceutical Development & Commercialization, Inc.	Phase 3
Terminated	Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Thera NCT01111552	Otsuka Pharmaceutical Development & Commercialization, Inc.	Phase 3
Terminated	Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Thera NCT01111539	Otsuka Pharmaceutical Development & Commercialization, Inc.	Phase 3
Completed	Light, Ion, and Fluoxetine Efficacy (LIFE) in Depression NCT00958204	University of British Columbia	Phase 3
Completed	A Duloxetine Dosing Strategy Study in Korean Patients With Major Depressive Disorder NCT00960986	Eli Lilly and Company	Phase 4
Completed	Efficacy Study of RX-10100 to Treat Major Depressive Disorder (MDD) NCT00839176	Rexahn Pharmaceuticals, Inc.	Phase 2
Completed	Retrospective TMS Therapy for Adults With MDD NCT05541302	Neuronetics	—
Completed	Optimization of IV Ketamine for Treatment Resistant Depression NCT00768430	Baylor College of Medicine	Phase 2
Completed	The WORKER Study: Escitalopram and Telephone-based Cognitive Behaviour Therapy (CBT) for Depressed Working Peo NCT00702598	University of British Columbia	N/A
Completed	Feasibility Study to Test Clinical Efficacy of Low Energy AC Magnetic Field to Treat Major Depression NCT01683019	Wave Neuroscience	N/A
Completed	Patient Tolerability Study of GSK163090 NCT00559299	GlaxoSmithKline	Phase 1
Completed	A Efficacy Study of PRX-00023 in Patients With Major Depressive Disorder NCT00448292	Epix Pharmaceuticals, Inc.	Phase 2
Completed	Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder NCT00411242	Novartis	Phase 3
Completed	A Local Register Study For Major Depression Of Paroxetine Controlled Release NCT00368303	GlaxoSmithKline	Phase 3
Completed	Study Of Bupropion SR (323U66) In Patients With Major Depressive Disorder In Japan NCT00330616	GlaxoSmithKline	Phase 2
Completed	Study Of GW679769 In Major Depressive Disorder NCT00102492	GlaxoSmithKline	Phase 2
Completed	Sexual Functioning Study With Antidepressants NCT00316160	GlaxoSmithKline	Phase 4
Completed	Lethargic Depression Study NCT00064467	GlaxoSmithKline	Phase 3
Completed	Depression Study In Elderly Patients NCT00067444	GlaxoSmithKline	Phase 3
Completed	An 8 Week Depression Study In Adults Diagnosed With Major Depressive Disorder NCT00057239	GlaxoSmithKline	Phase 2
Completed	Effects Of Antidepressants On Sexual Functioning In Adults NCT00051272	GlaxoSmithKline	Phase 3
Completed	Effects of Antidepressants on Sexual Functioning NCT00051259	GlaxoSmithKline	Phase 3