NCT07014683

Integral Cognitive Remediation for Depression

INtegral Cognitive REMediation for Depression (INCREM). Multicentric Randomized Clinical Trial to Investigate Feasibility and Efficacy (Phase II)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 101 (actual)
• Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to learn if INCREM intervention can improve psychosocial functioning in patients with remitted major depressive disorder. The main question it aims to answer are: Does INCREM improve psychosocial functioning compared to psychoeducation? Does the benefits of INCREM remain after six months of the intervention compared to psychoeducation? Researchers will compare two arms: INCREM; psychoeducation to see if psychosocial functioning improves. Participants will be allocated to: * INCREM * Psychoeducation * TAU.

Conditions

• Major Depressive Disorder (MDD)

Interventions

Type	Name	Description
BEHAVIORAL	INCREM	This is a specifically designed program to improve psychosocial functioning which targets cognitive symptoms.
BEHAVIORAL	Psychoeducation	This is a 12-session psychoeducation program designed as an active comparator for the current trial

Timeline

• Start date: 2021-09-19
• Primary completion: 2023-08-13
• Completion: 2023-08-13
• First posted: 2025-06-11
• Last updated: 2025-06-11

Locations

1 site across 1 country: Spain