| Not Yet Recruiting | A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV) Polycythemia Vera | Phase 3 | 2026-06-01 |
| Recruiting | IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Relapsed/Refractory Primary Central Nervous System Lymphoma | Phase 3 | 2026-03-01 |
| Not Yet Recruiting | A Retrospective Observational Study of Nivolumab in Combination With Chemotherapy as Neoadjuvant Therapy for R Non Small Cell Lung Cancer NSCLC | — | 2026-01-31 |
| Recruiting | ONO-4538 Study in Patients With Richter's Transformation Richter's Transformation | Phase 2 | 2025-11-19 |
| Recruiting | A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With m Colorectal Cancer | Phase 2 | 2025-11-18 |
| Active Not Recruiting | A Study to Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe He Primary Central Nervous System Lymphoma (PCNSL) | Phase 1 | 2025-10-01 |
| Recruiting | A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease Dementia Agitation Associated With Alzheimer's Disease Dementia | Phase 2 | 2025-05-01 |
| Active Not Recruiting | A Study of ONO-2020 in Participants With Mild to Moderate Alzheimer's Disease Alzheimer Disease | Phase 2 | 2025-04-24 |
| Recruiting | A Study of ONO-7428 in Participants With Unresectable Advanced or Recurrent Solid Tumors Solid Tumor, NSCLC | Phase 1 | 2025-04-21 |
| Active Not Recruiting | A Clinical Study of ONO-1110 in Patients With Hunner Type Interstitial Cystitis Hunner Type Interstitial Cystitis | Phase 2 | 2025-04-02 |
| Active Not Recruiting | A Clinical Study of ONO-1110 in Patients With Fibromyalgia Fibromyalgia | Phase 2 | 2025-03-26 |
| Active Not Recruiting | A Study of ONO-1110 in Patients With Postherpetic Neuralgia Postherpetic Neuralgia | Phase 2 | 2025-02-12 |
| Active Not Recruiting | A Study of ONO-1110 in Patients With Social Anxiety Disorder Social Anxiety Disorder (SAD) | Phase 2 | 2025-01-16 |
| Active Not Recruiting | A Study of ONO-1110 in Patients With Major Depressive Disorder Major Depressive Disorder (MDD | Phase 2 | 2025-01-16 |
| Not Yet Recruiting | Real-World Evidence of Effectiveness and Safety of Tirabrutinib in Patients with Relapsed or Refractory Primar Primary Central Nervous System Lymphoma (PCNSL) | — | 2024-12-01 |
| Active Not Recruiting | A Study of ONO-7018 in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma Non Hodgkin Lymphoma | Phase 1 | 2024-11-27 |
| Recruiting | Study to ONO-4538 in Patients With Rhabdoid Tumor Rhabdoid Tumor | Phase 2 | 2024-11-25 |
| Active Not Recruiting | Phase I Study Evaluating Tolerability, Safety, Pharmacokinetics, and Efficacy of Combined ONO-4059 and R-MPV T Primary Central Nervous System Lymphoma | Phase 1 | 2024-05-17 |
| Active Not Recruiting | A Phase I Study of ONO-4538HSC in Subjects With Advanced or Metastatic Solid Tumors Advanced or Metastatic Solid Tumors | Phase 1 | 2024-05-07 |
| Active Not Recruiting | A Study to Investigate the Efficacy and Safety of ONO-4578 in Combination With Nivolumab and Chemotherapy in C Gastric Cancer | Phase 2 | 2024-01-10 |
| Active Not Recruiting | A PhaseⅠStudy of ONO-7475 in Combination With ONO-4538 and Gemcitabine Plus Nab-paclitaxel (GnP), the Standard Metastatic Pancreatic Cancer | Phase 1 | 2023-12-06 |
| Recruiting | A Phase I Study to Investigate the Tolerability and Safety of ONO-4685 Given as Monotherapy in T Cell Lymphoma Relapsed or Refractory T Cell Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Phase 1 | 2023-10-01 |
| Active Not Recruiting | A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy Multiple System Atrophy (MSA) | Phase 2 | 2023-09-22 |
| Completed | Study to Investigate the Chemotherapy-Induced Peripheral Neuropathy (CIPN) Onset-Suppressing Effect and Safety CIPN - Chemotherapy-Induced Peripheral Neuropathy | Phase 2 | 2023-08-31 |
| Active Not Recruiting | A Study to Investigate the Safety, Tolerability, PK, PD, and Efficacy of ONO-7018 in Patients With R/R NHL or Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell | Phase 1 | 2023-02-13 |
| Recruiting | Safety of Cenobamate in Japanese Subjects With Partial Onset Seizures Epilepsies, Partial | Phase 2 | 2022-11-04 |
| Recruiting | ONO-4059 Study in Patients With Steroid-resistant Pemphigus Pemphigus, Steroid-resistant Pemphigus | Phase 3 | 2022-08-15 |
| Completed | A Phase 1 Study of ONO-2020 in Healthy Participants Healthy Volunteers | Phase 1 | 2022-07-29 |
| Recruiting | ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures. Epilepsy, Generalized | Phase 3 | 2022-07-12 |
| Completed | Safety, Tolerability, PK, PD and Preliminary Efficacy of ONO-4685 Plaque Psoriasis | Phase 1 | 2022-03-25 |
| Terminated | Study of ONO-7914 Alone and in Combination With ONO-4538 in Patients With Solid Tumors Solid Tumor | Phase 1 | 2022-02-08 |
| Active Not Recruiting | Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study) Refractory Primary Central Nervous System Lymphoma, Primary CNS Lymphoma | Phase 2 | 2021-12-29 |
| Recruiting | Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma Relapsed or Refractory T Cell Lymphoma | Phase 1 | 2021-12-10 |
| Active Not Recruiting | ONO-4578-06:Phase I Study of ONO-4578 and Letrozole Plus CDK4 /6 Inhibitors in Breast Cancer Hormone Receptor-positive Breast Cancer, HER2-negative Breast Cancer, Metastatic Breast Cancer | Phase 1 | 2021-11-09 |
| Active Not Recruiting | A Study to Evaluate the Efficacy and Safety of ONO-4538 in Combination With Ipilimumab and Chemotherapy in Che Gastric Cancer | Phase 3 | 2021-11-05 |
| Active Not Recruiting | The Study of ONO-7913, ONO-4538 and the Standard of Care as First-line Treatment in Patients Colorectal Cancer Unresectable Colorectal Cancer | Phase 1 | 2021-09-23 |
| Completed | Study of ONO-7475 in Combination With Osimertinib in EGFR Gene Mutation-positive Non-small Cell Lung Cancer Stage IIIB Non-small Cell Lung Cancer, Stage IIIC Non-Small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer | Phase 1 | 2021-08-06 |
| Active Not Recruiting | An Open-label, Uncontrolled Study of ONO-7913 and ONO-4538 in Combination With Modified FOLFIRINOX Therapy, th Metastatic Pancreatic Cancer | Phase 1 | 2021-07-30 |
| Active Not Recruiting | An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Docetaxel and Non-small Cell Lung Cancer | Phase 1 | 2021-06-01 |
| Completed | An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Modified FOLFI Metastatic Pancreatic Cancer | Phase 1 | 2021-01-13 |
| Active Not Recruiting | Study of ONO-4578 and XELOX/FOLFOX Plus Bevacizumab in Colorectal Cancer Colorectal Cancer | Phase 1 | 2021-01-13 |
| Completed | A Study of FOY-305 in Patients With SARS-Cov-2 Infection (COVID-19) SARS-CoV-2 Infection (COVID-19) | Phase 3 | 2020-11-09 |
| Recruiting | ONO-4538 Phase II Rollover Study (ONO-4538-98) Pan-tumor | Phase 2 | 2020-09-10 |
| Completed | A First in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of ONO-2808-01 in Healthy Parti Neurodegenerative Diseases | Phase 1 | 2020-08-19 |
| Completed | ONO-7913 Phase I Study (ONO-7913) Solid Tumor | Phase 1 | 2020-07-28 |
| Completed | Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability and PK of ONO-2910 in Japanese and Healthy Volunteers | Phase 1 | 2020-07-10 |
| Completed | Multiple-dose Study of FOY-305 in Japanese Healthy Adult Male Subjects Healthy Volunteers | Phase 1 | 2020-07-01 |
| Completed | Single Ascending Dose Study to Assess the Safety, Tolerability, PK and PD of ONO-4685 in Japanese and Caucasia Healthy Volunteers | Phase 1 | 2019-09-12 |
| Completed | Single-dose Study to Evaluate the Absolute Bioavailability and Mass Balance of ONO-5788 Acromegaly | Phase 1 | 2019-02-27 |
| Completed | A Two-Part Study to Assess the Safety, Tolerability, PK and PD of ONO-7684 in Healthy Adult Volunteers Venous Thromboembolism | Phase 1 | 2019-01-17 |
| Completed | Phase 1 Study of ONO-7475 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors Advanced or Metastatic Solid Tumors | Phase 1 | 2018-10-17 |
| Terminated | A Four-Part Study to Assess the Safety, Tolerability, PK and PD of ONO-5788 in Healthy Adult Volunteers Acromegaly | Phase 1 | 2018-06-07 |
| Terminated | Study of ONO-7579 in Patients With Advanced Solid Tumors/ NTRK Gene Fusion Positive Advanced Solid Tumors Solid Tumor | Phase 1 | 2017-07-12 |
| Terminated | A Study of ONO-7475 in Patients With Acute Leukemias Acute Leukemia, Myelodysplastic Syndromes | Phase 1 / Phase 2 | 2017-06-26 |
| Completed | Study of ONO-4538 in Non-Squamous Non-Small Cell Lung Cancer (TASUKI-52) Non-Small Cell Lung Cancer | Phase 3 | 2017-06-13 |
| Active Not Recruiting | Study of ONO-4578 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors Advanced or Metastatic Solid Tumors | Phase 1 | 2017-04-19 |
| Completed | Study of ONO-8577 in Patients With Overactive Bladder Overactive Bladder | Phase 2 | 2017-04-07 |
| Completed | Study of Adjuvant ONO-4538 With Resected Gastric Cancer Gastric Cancer | Phase 3 | 2017-01-31 |
| Terminated | A Study to Evaluate ONO-4474 in Patients With Pain Due to Osteoarthritis of the Knee Osteoarthritis, Knee, Pain | Phase 2 | 2017-01-01 |
| Completed | Study of ONO-4538 in Gastric Cancer Gastric Cancer | Phase 2 / Phase 3 | 2016-03-01 |
| Completed | ONO-4538 Study in Patients With Advanced Non-Small Cell Lung Cancer Advanced Non-small Cell Lung Cancer | Phase 2 | 2016-01-27 |
| Completed | Study of Nivolumab in Unresectable Advanced or Recurrent Esophageal Cancer Esophageal Cancer | Phase 3 | 2015-12-14 |
| Completed | A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacology of ONO-4474 in Healthy Volunteers Osteoarthritis | Phase 1 | 2015-05-01 |
| Completed | Study of ONO-4538 in Unresectable Advanced or Recurrent Gastric Cancer Gastric Cancer | Phase 3 | 2014-10-01 |
| Completed | ONO-4538 Phase I Study in Patients With Solid Tumor Advanced Solid Tumors, Recurrent Solid Tumors | Phase 1 | 2014-10-01 |
| Completed | ONO-4538 Phase I Study in Patients With Solid Tumor Advanced Solid Tumors, Recurrent Solid Tumors | Phase 1 | 2014-10-01 |
| Completed | ONO-4538 Study in Patients With Advanced Non-Small Cell Lung Cancer Advanced Non-small Cell Lung Cancer (NSCLC) | Phase 2 | 2014-06-01 |
| Completed | A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glauco Ocular Hypertension, Open Angle-glaucoma | Phase 2 | 2014-05-01 |
| Completed | A Human Mass Balance Study to Determine the Total Recovery of Radioactivity in Urine and Faeces Following a Si Healthy Adult Male Subjects | Phase 1 | 2013-10-01 |
| Completed | A Study to Investigate the Effect of ONO-8539 on Acid-Induced Oesophageal Hypersensitivity in Healthy Voluntee Acid Reflux | Phase 1 | 2013-01-01 |
| Completed | A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Dis GERD | Phase 1 | 2012-12-01 |
| Completed | Phase II Study Evaluating ONO-4053 and Cetirizine in Subjects With Seasonal Allergic Rhinitis Seasonal Allergic Rhinitis | Phase 2 | 2012-11-01 |
| Completed | A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers Healthy Adult Subjects | Phase 1 | 2012-01-01 |
| Terminated | A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers Healthy Adult Subjects | Phase 1 | 2011-06-01 |
| Completed | A Study to Investigate the Effects of Food and Morning Versus Evening on Single and Multiple Doses of ONO-5334 Healthy Post Menopausal Women | Phase 1 / Phase 2 | 2011-06-01 |
| Completed | ONO-7746 Study in Healthy Adult Subject Healthy Adult Subjects | Phase 1 | 2010-04-01 |
| Completed | ONO-7746 Study in Healthy Adult Subjects Healthy Adult Subjects | Phase 1 | 2009-08-01 |
| Completed | Study of ONO-1101 in Patients Scheduled for Multi-Slice Computed Tomography (CT) Coronary Artery Disease | Phase 3 | 2009-06-01 |
| Completed | Study of ONO-8539 in Patients With Overactive Bladder Overactive Bladder | Phase 2 | 2009-04-01 |
| Completed | MK-0431/ONO-5435 Phase III Clinical Trial - Insulin Add-on Study for Patients With Type 2 Diabetes Mellitus Type 2 Diabetes Mellitus | Phase 3 | 2009-02-01 |
| Completed | ONO-4538 Phase I Study in Patients With Advanced Malignant Solid Tumors in Japan Malignant Solid Tumor | Phase 1 | 2009-01-01 |
| Completed | A Phase II Multi-centre, Extension Study to Investigate the Long Term Safety of ONO-2506PO in Patients Diagnos Amyotrophic Lateral Sclerosis (ALS) | Phase 2 | 2008-06-01 |
| Completed | Study of ONO-1101 in Patients Scheduled for Coronary Angiography Coronary Artery Disease | Phase 2 | 2007-11-01 |
| Completed | Long-term Safety and Efficacy of Imidafenacin in Patients With Overactive Bladder Overactive Bladder | Phase 3 | 2007-08-01 |
| Completed | Study of ONO-1078 in Patients With Chronic Sinusitis Chronic Sinusitis | Phase 3 | 2006-12-01 |
| Completed | Controlled Study of ONO-5046Na in Patients With Acute Respiratory Failure Associated With Community-Acquired P Community-acquired Pneumonia | Phase 2 | 2006-12-01 |
| Completed | Placebo Controlled Study of ONO2506PO in the Presence of Riluzole in Patients With Amyotrophic Lateral Scleros Amyotrophic Lateral Sclerosis (ALS) | Phase 2 | 2006-11-01 |
| Completed | Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus Type 2 Diabetes Mellitus | Phase 3 | 2006-08-01 |
| Completed | Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus Type 2 Diabetes Mellitus | Phase 3 | 2006-08-01 |
| Completed | Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus Type 2 Diabetes Mellitus | Phase 3 | 2006-08-01 |
| Completed | Pilot Study of ONO-1101 in Patients Scheduled for Multi-slice CT Coronary Artery Disease | Phase 2 | 2006-04-01 |
| Completed | Study of ONO-2506 in Patients With Acute Ischemic Stroke Stroke | Phase 2 / Phase 3 | 2005-09-01 |
| Completed | ONO-7436 Phase II Study in Japan Malignant Tumor | Phase 2 | 2005-08-01 |
| Completed | Controlled Study of ONO-5920 in Patients With Involutional Osteoporosis in Japan Involutional Osteoporosis | Phase 3 | 2004-06-01 |
| Completed | Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response S Acute Lung Injury, Systemic Inflammatory Response Syndrome | Phase 4 | 2004-06-01 |
| Completed | Controlled Study of ONO-2506PO in Patients With Parkinson's Disease in Japan Parkinson's Disease | Phase 2 | 2004-01-01 |
| Completed | Controlled Study of ONO-8025 (KRP-197) in Patients With Overactive Bladder in Japan Overactive Bladder | Phase 3 | 2003-10-01 |
| Completed | Controlled Study of ONO-5920 in Patients With Involutional Osteoporosis in Japan Involutional Osteoporosis | Phase 3 | 2003-05-01 |
| Completed | Controlled Study of ONO-5920 in Patients With Involutional Osteoporosis in Japan Involutional Osteoporosis | Phase 3 | 2002-08-01 |
| Completed | Controlled Study of ONO-8025 (KRP-197) in Patients With Overactive Bladder in Japan Overactive Bladder | Phase 2 | 2001-10-01 |
| Completed | Controlled Study of ONO-1101 in Patients With Postoperative Tachyarrhythmias in Japan Postoperative Supraventricular Tachyarrythmia | Phase 2 / Phase 3 | 2001-06-01 |
| Completed | MK-0431/ONO-5435 Phase III Clinical Trial-Rapid-acting Insulin Secretagogue Add-on Study in Patients With Type Type 2 Diabetes | Phase 3 | — |