Trials / Active Not Recruiting
Active Not RecruitingNCT07198087
A Study to Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy Participants
A Phase 1, Open-Label, Parallel-Group Study to Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy Participants
- Status
- Active Not Recruiting
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- Ono Pharmaceutical Co., Ltd. · Industry
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
A study to investigate the pharmacokinetics of tirabrutinib in participants with mild, moderate, and severe hepatic impairment compared to healthy participants
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Tirabrutinib | Administered orally |
Timeline
- Start date
- 2025-10-01
- Primary completion
- 2026-04-09
- Completion
- 2026-12-31
- First posted
- 2025-09-30
- Last updated
- 2026-04-16
Locations
3 sites across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT07198087. Inclusion in this directory is not an endorsement.