Clinical Trials Directory

Trials / Conditions / Hyperuricemia

Hyperuricemia

153 registered clinical trials studyying Hyperuricemia13 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingChronic Kidney Disease and Metabolic Disorders in the Elderly
NCT07494526
Chinese PLA General Hospital
RecruitingEvaluation of Efficacy and Safety of AR882 and XOI Co-administration in Uricase Treatment Failed Patients
NCT07116746
Arthrosi TherapeuticsPhase 2
Not Yet RecruitingIs There a Relationship Between Uric Acid Level and Liver Fibrosis in Obese Patients
NCT07168551
Assiut University
RecruitingThis Study is to Estimate the Efficacy of Hemodialysis Alone for Uric Acid Clearance in Patients on Hemodialys
NCT07144332
Sohag University
RecruitingEffects of Fibres Combined With Probiotics on Uric Acid in an ex Vivo Fermentation Model
NCT06981663
Örebro University, Sweden
RecruitingProspective Exploratory Study on the Comprehensive Application Effectiveness of Exercise Prescription Decision
NCT07400549
China National Center for Cardiovascular DiseasesN/A
Enrolling By InvitationMetabolically Healthy Obesity Increases the Risks of MASLD and Hyperuricemia
NCT07001865
Ningbo No. 1 Hospital
Active Not RecruitingPhase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-301)
NCT06846515
Arthrosi TherapeuticsPhase 3
RecruitingA Research Study to Evaluate the Safety of NNC4004-0002 When Given to Participants With Asymptomatic Hyperuric
NCT06859073
Novo Nordisk A/SPhase 1
RecruitingA Dose Escalation Study of IG3018 in Subjects With Hyperuricemia With or Without Chronic Kidney Disease
NCT06310967
Intelligem Therapeutics Australia Pty Ltd.Phase 1 / Phase 2
Not Yet RecruitingScreening and Management of Hyperuricemia in Patients with Chronic Medical Diseases in Assiut University Hospi
NCT06586229
Assiut University
RecruitingCPAP Effect on Lipid Profile and Hyperuricemia in Patients With Dyslipidemia and Moderate-severe Obstructive S
NCT06463561
Hospital Universitario La PazPhase 4
CompletedA Dose Finding Study to Assess Efficacy and Safety of IBI128 in Chinese Gout Subjects
NCT06501534
Innovent Biologics (Suzhou) Co. Ltd.Phase 2
Active Not RecruitingPhase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-302)
NCT06439602
Arthrosi TherapeuticsPhase 3
CompletedThe Effect of Exercise at Different Time Intervals on Hyperuricemia
NCT06315569
Xijing HospitalN/A
CompletedEffect of Increased Daily Water Intake in Patients With Hyperuricemia
NCT06315543
Xijing HospitalN/A
Active Not RecruitingPK and Safety Evaluation Study of SAP-001 in Adult Subjects With Normal and Impaired Renal Function
NCT06729853
Shanton Pharma Pte. Ltd.Phase 1 / Phase 2
Active Not RecruitingPhase II/III Study of AR882 Capsules Compared to Febuxostat Tablets in Patients with Primary Gout and Hyperuri
NCT06603142
Guangzhou Ruianbo Pharmaceutical Technology Co., LtdPhase 2 / Phase 3
CompletedBioequivalence Study of 2 Sizes of SHR4640 Tablets Orally in Healthy Subjects
NCT06168929
Jiangsu HengRui Medicine Co., Ltd.Phase 1
CompletedEffectiveness of Digital Health Intervention on Community Health Care in Middle-aged and Older Population in T
NCT07238257
Chang Gung Memorial HospitalN/A
RecruitingSafety, Tolerability, and Pharmacokinetic Characteristics of SSS11 in Patients With Gout and Hyperuricemia
NCT06629376
Shenyang Sunshine Pharmaceutical Co., LTD.Phase 1
CompletedEffect of Tigulixostat on the Pharmacokinetics of Theophylline
NCT06189404
LG ChemPhase 1
UnknownThe Efficacy of Amway Uric Acid Lowering Product on Hyperuricemia
NCT06084585
Amway (China) R&D CenterN/A
CompletedOpen Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients with Hyperuricemia
NCT06056570
Urica Therapeutics Inc.Phase 1 / Phase 2
CompletedQuercetin as Possible Supportive Therapy for Mild to Moderate Hyperuricemia
NCT06591767
Liaquat University of Medical & Health SciencesN/A
CompletedRelationship Between Intestinal Flora Changes and Hyperuricemia Under Chronic Psychological Stress
NCT06984575
Shanghai 10th People's Hospital
CompletedPharmacokinetic/Pharmacokinetic and Safety Studies of SHR4640 in Subjects With Moderate Renal Insufficiency an
NCT05954169
Jiangsu HengRui Medicine Co., Ltd.Phase 1
UnknownEfficacy and Safety of Kui-Yuan Chewable Tablets in Patients With Hyperuricemia
NCT05913310
Quan JiangPhase 4
CompletedSAD,MAD and Food Effect Study of SAP-001 Tablets in Chinese Subjects
NCT06678581
Shanton Pharma Co., Ltd.Phase 1
CompletedTigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients
NCT05586971
LG ChemPhase 3
CompletedTigulixostat, Phase 3 Study, Placebo Controlled in Gout Patients
NCT05586958
LG ChemPhase 3
CompletedEvaluate the Efficacy and Safety of D-0120 in Primary Hyperuricemia Patients
NCT05504083
InventisBio Co., LtdPhase 2
Active Not RecruitingImagery as Biomarker of Gout
NCT05434858
Lille Catholic UniversityN/A
TerminatedPhase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney
NCT04987294
Allena PharmaceuticalsPhase 2
Active Not RecruitingComparative Study Between Febuxostat Versus Vitamin E in Non-alcoholic Steatohepatitis Patients With Hyperuric
NCT05574036
Tanta UniversityPhase 2
CompletedPhase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination With Allopurinol in Patients With Topha
NCT05253833
Arthrosi TherapeuticsPhase 2
RecruitingRisk Factors and Multiomics Study of Chronic Kidney Disease Caused by Metabolic Diseases
NCT05476627
Peking Union Medical College Hospital
UnknownAssocaiton Between Uric Acid Trajecteries and Remission of NAFLD in NAFLD Individuals
NCT05245890
Ningbo No. 1 Hospital
CompletedScintigraphy Study in Healthy Volunteers to Characterize the Performance of ALLN-346 Tablets
NCT05168683
Allena PharmaceuticalsPhase 1
UnknownPrediction of UA/SOD Ratio as a Biomarker of Oxidative Stress in Atrial Fibrillation
NCT06119802
Yinglong Hou
CompletedFebuxostat Versus Allopurinol on Hepatic Steatosis in MAFLD Patients
NCT05474560
Ain Shams UniversityPhase 4
Active Not RecruitingTreat-to-target by Email During Urate-lowering Therapy in Gout
NCT04733079
Assistance Publique - Hôpitaux de ParisN/A
UnknownTolerance, Pharmacokinetics / Pharmacodynamics (PK / PD) and Immunogenicity of Pegylated Uric Acid Oxidase for
NCT05226013
The Affiliated Hospital of Qingdao UniversityPhase 1
CompletedPhase 2b Evaluation of Efficacy and Safety of AR882 in Gout Patients
NCT05119686
Arthrosi TherapeuticsPhase 2
CompletedThorough QT (TQT) Study to Evaluate the Effect of LC350189 on Cardiac Repolarization in Healthy Male and Femal
NCT04966325
LG ChemEARLY_Phase 1
CompletedPossible Pharmacological Effect of Quercetin in the Management of Hyperuricemia - Results From Real-life Clini
NCT06652035
Liaquat University of Medical & Health Sciences
CompletedClinical Effect Observation of Barley Green Intervention in Hyperuricemia Population and Related Mechanism Stu
NCT06876909
Peking University People's HospitalN/A
CompletedRelative Bioavailability Study to Assess an LC350189 Tablet Compared to an LC350189 Capsule in Healthy Adults
NCT04886050
LG ChemPhase 1
CompletedAn Inpatient Study of ALLN-346 (Engineered Urate Oxidase) in Hyperuricemic Subjects (Study 201)
NCT04987242
Allena PharmaceuticalsPhase 2
UnknownResearch and Development of a New Technology for Detection of Abnormal Excretion of Intestinal Uric Acid Invol
NCT04953533
Second Affiliated Hospital, School of Medicine, Zhejiang University
CompletedNon-Inferiority Study of Aliskiren vs Losartan in the Treatment of Hypertension With Hyperuricemia
NCT06718062
Hansung UniversityPhase 4
CompletedStudy 102: Multiple Ascending Dose Study of ALLN-346 (Engineered Urate Oxidase)
NCT04829435
Allena PharmaceuticalsPhase 1
UnknownHyperuricemia and Diabetic Nephropathy
NCT04799925
Assiut University
CompletedHmong Microbiome ANd Gout, Obesity, Vitamin C (HMANGO-C)
NCT04938024
University of MinnesotaN/A
CompletedVegan Diet, Amla Fruits and Uric Acid
NCT04801745
Fu Jen Catholic UniversityN/A
WithdrawnPost-Authorisation Safety Study of Lesinurad
NCT04072471
AstraZeneca
CompletedA Study to Assess the Efficacy, Safety, and Pharmacokinetics of ABP-671 in Patients With Gout or Hyperuricemia
NCT04638543
Atom Therapeutics Co., LtdPhase 2
CompletedA Safety and Tolerability Study of FCN-207 in Healthy Volunteers
NCT04622124
Fochon Pharmaceuticals, Ltd.Phase 1
UnknownStudy on the Bioavailability of Three Different Prescription Processes of SHR4640 Tablets in Healthy Volunteer
NCT04586803
Jiangsu HengRui Medicine Co., Ltd.Phase 1
CompletedALLN-346 Single Ascending Dose (SAD) Study in Healthy Volunteers
NCT04236219
Allena PharmaceuticalsPhase 1
UnknownXanthine Oxidase and Uric Acid Origin in Preeclamptic Women
NCT04463940
Barzilai Medical Center
UnknownRole of Uralyt-U in Patients With Hyperuricemia
NCT04352153
Ai PengN/A
CompletedMass Balance Study of [14C]LC350189 in Healthy Volunteers
NCT04070846
LG ChemPhase 1
UnknownUrate Lowering Therapies and Left Ventricular Diastolic Dysfunction
NCT03534037
National Defense Medical Center, TaiwanPhase 4
CompletedThe Effect of Naproxen on the Pharmacokinetic Profile of LC350189 in Healthy Adults
NCT04139824
LG ChemPhase 1
UnknownUric Acid Lowering Trial in Youth Onset T2D
NCT03899883
University of Colorado, DenverPhase 2
UnknownA Safety and Efficacy Study of SHR4640 and Febuxostat in Subjects With Hyperuricemia
NCT04180982
Jiangsu HengRui Medicine Co., Ltd.Phase 2
CompletedA Study to Assess Efficay and Safety of LC350189 Different Doses in Gout Patients With Hyperuricemia
NCT03934099
LG ChemPhase 2
CompletedRenal PK Study of LC350189
NCT04066712
LG ChemPhase 1
CompletedEffect of the Consumption of a Combination of Plant Extracts (BSL_EP026) on Serum Uric Acid.
NCT04165499
Biosearch S.A.EARLY_Phase 1
CompletedThe Effect of Colchicine on the Pharmacokinetic Profile of LC350189 in Healthy Aldults.
NCT03927677
LG ChemPhase 1
UnknownThe Drug-Drug Interaction of SHR4640 and Febuxostat in Patients With Hyperuricemia
NCT04157959
Jiangsu HengRui Medicine Co., Ltd.Phase 1
CompletedA Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABP-671
NCT04060173
Atom Therapeutics Co., LtdPhase 1
UnknownEffects of Allopurinol on Inflammation and Ultrasonographic Changes in People With Elevated Uric Acid But no S
NCT04012294
Instituto Nacional de Cardiologia Ignacio ChavezPhase 3
UnknownThe Effects of Rhus Coriaria L. on Serum Uric Acid Levels
NCT02891031
Shiraz University of Medical SciencesN/A
TerminatedUric Acid Reduction as a Novel Treatment for Pediatric Chronic Kidney Disease
NCT03865407
Virginia Commonwealth UniversityPhase 2
UnknownEffect of Oxalate and Urate Metabolism on CKD Evolution
NCT04399915
The Institute of Nephrology of the Academy of Medical Sciences of Ukraine
CompletedPlacebo Controlled, Multiple Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynami
NCT04040816
Shanton Pharma Co., Ltd.Phase 2
UnknownThe Long Term Effect of Low Dose Aspirin on Uric Acid in Chinese Patients With Coronary Artery Disease(AURORA)
NCT03691688
Shanghai Zhongshan Hospital
UnknownProbiotics for Gout / Hyperuricemia: A Randomized, Intervention, Parallel Controlled, Multicenter Clinical Tri
NCT04199325
The Affiliated Hospital of Inner Mongolia Medical UniversityN/A
CompletedSex-related Differences in Arterial Stiffness in Type 2 Diabetics: Role of Uric Acid
NCT03648996
University of Missouri-ColumbiaPhase 2
CompletedA Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABP-671 in Healthy Subjec
NCT03906006
Atom Therapeutics Co., LtdPhase 1
CompletedNutraceutical on Hyperuricemia
NCT04161872
University of PaviaPhase 4
CompletedThe Diet Gout Trial
NCT03569020
Johns Hopkins UniversityN/A
UnknownThe Relationship Among, Serum Uric Acid, Left Ventricular Hypertrophy and Metabolic Syndrome
NCT03473951
National Defense Medical Center, Taiwan
UnknownPrevalence of Hyperuricemia in Pakistan
NCT03473444
OBS Pakistan
TerminatedHyperuricemia and Left Ventricular Diastolic Function
NCT03495999
National Defense Medical Center, Taiwan
CompletedDose-finding and Safety Study of SHR4640 in Subjects With Hyperuricemia
NCT03185793
Jiangsu HengRui Medicine Co., Ltd.Phase 2
UnknownLowering-hyperuricemia Treatment on Cardiovascular Outcomes in Peritoneal Dialysis Patients
NCT03200210
Sun Yat-sen UniversityPhase 4
CompletedMultiple Doses Study of SHR4640 in Male Subjects With High Serum Uric Acid Level
NCT03211403
Atridia Pty Ltd.Phase 1
CompletedIntensive Uric Acid Lowering With Verinurad and Febuxostat in Patients With Albuminuria
NCT03118739
AstraZenecaPhase 2
WithdrawnGender Differences in the Metabolic Effects of Uric Acid
NCT03076684
University of Missouri-ColumbiaEARLY_Phase 1
CompletedUse of Febuxostat in Hyperuricemia Among Hemodialysis Patients
NCT03149939
Benha UniversityN/A
UnknownThe Intervention of Multi-vitamin With Minerals to Hyperuricemia
NCT03218709
Sun Yat-sen UniversityPhase 4
UnknownEffect of Hyperuricaemia on Chronic Renal Disease
NCT03425708
The Affiliated Hospital of Xuzhou Medical UniversityPhase 4
CompletedThe Effects of BCRP Q141K on Allopurinol Pharmacokinetics and Dynamics
NCT02956278
University of California, San FranciscoPhase 4
CompletedMulti-Dose Safety/Pharmacodynamic Study of SEL-212/SEL-037 in Subjects With Symptomatic Gout & Elevated Blood
NCT02959918
Selecta Biosciences, Inc.Phase 2
UnknownCompare the Renal Protective Effects of Febuxostat and Benzbromarone in CKD Chinese Patients
NCT02944214
Shanghai 10th People's HospitalN/A
CompletedStudy of FYU-981 in Hyperuricemia (Effect on Two Hyperuricemic Types)
NCT02837198
Fuji Yakuhin Co., Ltd.Phase 2
CompletedStudy of URC102 to Assess the Safety and Efficacy in Gout Patients
NCT02557126
JW PharmaceuticalPhase 2
TerminatedPharmacogenetics of SGLT2 Inhibitors
NCT02462421
University of Maryland, BaltimorePhase 4
CompletedStudy of FYU-981 in Hyperuricemia With or Without Gout
NCT02416167
Fuji Yakuhin Co., Ltd.Phase 2
CompletedCompare the Renal Protective Effects of Febuxostat and Benzbromarone
NCT02338323
Shanghai 10th People's HospitalN/A
CompletedThe Cardiovascular Protective Effects of Febuxostat in Peritoneal Dialysis Patients
NCT02338128
Shanghai 10th People's Hospital
CompletedEvaluate the PK, PD, and Safety of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Patients W
NCT02252835
Gilead SciencesPhase 2
CompletedPhase 2 Study of URC102 to Assess the Efficacy and Safety in Gout Patients
NCT02290210
JW PharmaceuticalPhase 2
CompletedEffect of Chrysanthemum Flower Oil and Its Dose-dependency on Hyperuricemia
NCT02213562
Hiroshima UniversityN/A
CompletedStudy of FYU-981 in Hyperuricemia With or Without Gout
NCT02344862
Fuji Yakuhin Co., Ltd.Phase 2
UnknownLong-term Prednisone Use for End-stage Heart Failure
NCT02282683
Hebei Medical UniversityPhase 2 / Phase 3
UnknownEffect of Allopurinol Treatment on Insulin Resistance
NCT02008968
Istanbul Medeniyet UniversityN/A
UnknownFebuxostat for Cerebral and caRdiorenovascular Events prEvEntion stuDy
NCT01984749
Freed Study GroupN/A
CompletedZurig (Febuxostat) 40mg Efficacy and Safety Trial
NCT02600780
Getz PharmaPhase 4
UnknownThe Influence of Antiphospholipid Antibodies on the Relationship Between Hyperurecemia, Gout and Metabolic Syn
NCT01818505
National Taiwan University Hospital
CompletedEffect of Quercetin Supplements on Healthy Males: a Four-Week Randomized Cross-Over Trial
NCT01881919
University of LeedsEARLY_Phase 1
CompletedPurine Metabolism Enzyme SNP to Uric Acid Production
NCT01830725
Keesler Air Force Base Medical Center
CompletedImpact of Blueberries on Uric Acid and Quality of Life
NCT01532622
University of Mississippi Medical CenterN/A
UnknownStudy of Levotofisopam 50 mg Three Times a Day (TID) Administered for 7 Days on Hyperuricemia and Gout
NCT01519687
PharmosPhase 2
UnknownMusculoskeletal Ultrasound in Asymptomatic Hyperuricemia
NCT02502565
Washington D.C. Veterans Affairs Medical Center
CompletedA Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to
NCT01407874
BioCryst PharmaceuticalsPhase 2
CompletedOpen Label Safety/Efficacy Study of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Gout Pati
NCT01416402
Gilead SciencesPhase 2
CompletedEffects of Green Tea on Level of Serum Uric Acid in Healthy Individuals
NCT01363869
Chiang Mai UniversityN/A
CompletedSafety, Tolerability and Pharmacokinetic/Pharmacodynamic Characteristics of LC350189
NCT01361646
LG Life SciencesPhase 1
CompletedSafety and Efficacy Study of MBX-102 in Treatment of Hyperuricemia in Patients With Gout
NCT01336686
Gilead SciencesPhase 2
CompletedStudy to Evaluate sUA Lowering Activity, Safety and Efficacy of Oral Ulodesine Added to Allopurinol
NCT01265264
BioCryst PharmaceuticalsPhase 2
CompletedTart Cherry Juice and Markers of Inflammation, CVD, and Diabetes
NCT03636529
University of MemphisN/A
CompletedTranilast Plus Allopurinol in Patients With Moderate to Severe Gout (TAnGO)
NCT01109121
Nuon Therapeutics, Inc.Phase 2
CompletedSafety and Efficacy of TULY (Rasburicase) in Prevention and Treatment of Malignancy-associated Hyperuricemia
NCT00921375
Virchow GroupPhase 3
CompletedStudy of Tranilast Alone or in Combination With Allopurinol in Subjects With Hyperuricemia
NCT01052987
Nuon Therapeutics, Inc.Phase 2
UnknownSafety and Efficacy Study of Intramuscular Uricase-PEG 20
NCT01038947
EnzymeRxPhase 1
UnknownSafety and Efficacy Study of Intravenous Uricase-PEG 20
NCT01021241
EnzymeRxPhase 1
CompletedStudy of Tranilast Alone or in Combination With Febuxostat in Patients With Hyperuricemia
NCT00995618
Nuon Therapeutics, Inc.Phase 2
CompletedGout Dose Response Study
NCT00955981
Ardea Biosciences, Inc.Phase 2
CompletedThe Role Of Fructose and Uric Acid In the Development of Obesity and Metabolic Syndrome
NCT00868673
Instituto Nacional de Cardiologia Ignacio ChavezN/A
CompletedPrednisone for Heart Failure Patients With Hyperuricemia
NCT00919243
Hebei Medical UniversityPhase 4
CompletedLowering Serum Uric Acid to Prevent Acute Kidney Injury
NCT00756964
University of FloridaPhase 2
CompletedPrimary Prevention of Hypertension in Obese Adolescents
NCT00288158
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Phase 2
CompletedA Study of RDEA806 in Hyperuricemic Subjects With Symptomatic Gout
NCT00741442
Ardea Biosciences, Inc.Phase 2
CompletedThe Effect of Uric Acid Decrement on Endothelial Function in Patients With Chronic Renal Failure
NCT00978653
Istanbul UniversityN/A
TerminatedRasburicase (Fasturtec) Registration Trial
NCT00607152
SanofiPhase 3
CompletedEffect of Reducing Uric Acid on Insulin Sensitivity and Oxidative Status
NCT01931527
Washington University School of MedicineN/A
CompletedTraditional Chinese Medicine in the Treatment of Patients With Hyperuricemia.
NCT04144088
Chung Shan Medical UniversityPhase 2
CompletedRasburicase in Tumor Lysis Syndrome
NCT00302653
SanofiPhase 4
CompletedRasburicase Treatment for Chemotherapy or Malignancy-Induced Hyperuricemia in Asthma/Allergy Patients
NCT00186940
St. Jude Children's Research Hospital
CompletedRasburicase Versus Allopurinol in Tumor Patients at Risk for Hyperuricemia and Tumor Lysis Syndrome
NCT00230178
SanofiPhase 3
CompletedStudy of Rasburicase as Treatment or Prevention of Hyperuricemia Associated With Tumor Lysis Syndrome in Patie
NCT00230217
SanofiPhase 4
CompletedTreatment of Hyperuricemia in Patients With Heart Failure
NCT00422318
Tottori University HospitalPhase 4
CompletedRasburicase as a Uricolytic Therapy for Hyperuricemia in Patients With Leukemia or Lymphoma
NCT00631579
SanofiPhase 2
CompletedRasburicase for Treatment of Hyperuricemia in Children and Adolescence Patients With Tumor Lysis Syndrome
NCT00563771
SanofiPhase 4
TerminatedRasburicase for the Treatment/Prevention of Hyperuricemia in Adult Patients With Relapsing Aggressive Non Hodg
NCT00664144
SanofiPhase 2
CompletedMagnetic Resonance Imaging in Subjects With Gouty Tophi
NCT00174954
Takeda
CompletedReversal of an Unfavorable Effect of Hydrochlorothiazide Compared to Angiotensin Converting Enzyme Inhibitor o
NCT03921736
Anna Posadzy-MałaczyńskaPhase 4
CompletedAllopurinol in Chronic Heart Failure
NCT00997542
National Heart and Lung InstitutePhase 4
CompletedPhase II Exploratory Clinical Study of KUX-1151
NCT02190786
Kissei Pharmaceutical Co., Ltd.Phase 2