Clinical Trials Directory

Trials / Completed

CompletedNCT04139824

The Effect of Naproxen on the Pharmacokinetic Profile of LC350189 in Healthy Adults

A Phase 1, Open-label, Fixed-sequence, 2-way Drug Interaction Study to Evaluate the Effect of Naproxen on the Pharmacokinetics of LC350189 and the Effect of LC350189 on the Pharmacokinetics of Naproxen in Healthy Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
24 (actual)
Sponsor
LG Chem · Industry
Sex
All
Age
18 Years – 50 Years
Healthy volunteers
Accepted

Summary

This is a Phase 1, open-label, fixed-sequence, 3-period, 2-way drug interaction study designed to assess the pharmacokinetics, pharmacodynamics, safety, and tolerability of LC350189 and Naproxen when administered alone and in combination in healthy subjects.

Conditions

Interventions

TypeNameDescription
DRUGXanthine Oxidase InhibitorLC350189 200mg qd
DRUGnonsteroidal anti-inflammatory drugNaproxen 500mg BID

Timeline

Start date
2020-01-22
Primary completion
2020-02-25
Completion
2020-02-25
First posted
2019-10-25
Last updated
2020-06-26

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04139824. Inclusion in this directory is not an endorsement.

The Effect of Naproxen on the Pharmacokinetic Profile of LC350189 in Healthy Adults (NCT04139824) · Clinical Trials Directory