Trials / Completed
CompletedNCT00997542
Allopurinol in Chronic Heart Failure
A Double-blind, Placebo-controlled, Cross-over Study of the Effects of Allopurinol on Oxidative Metabolism, Peripheral Blood Flow and Immune Function in Patients With Advanced Chronic Heart Failure (CHF).
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 16 (actual)
- Sponsor
- National Heart and Lung Institute · Academic / Other
- Sex
- Male
- Age
- 21 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to discover whether the inhibition of the xanthine oxidase with allopurinol leads to a reduction of the production of oxygen free radicals in patients with CHF and thereby improves characteristics of oxydative metabolism, peripheral blood flow, immune function and functional status.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Allopurinol | |
| DRUG | Placebo |
Timeline
- First posted
- 2009-10-19
- Last updated
- 2009-10-19
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT00997542. Inclusion in this directory is not an endorsement.