NCT06189404

Effect of Tigulixostat on the Pharmacokinetics of Theophylline

A Phase 1, Open-Label, Drug-Drug Interaction Study to Evaluate the Effect of Multiple Oral Doses of Tigulixostat on the Pharmacokinetics of a Single Oral Dose of Theophylline

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: LG Chem · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

A phase 1, open-label, drug-drug interaction study to evaluate the effect of multiple doses of tigulixostat on the pharmacokinetics of single-dose theophylline in healthy adult volunteers.

Conditions

• Gout
• Hyperuricemia

Interventions

Type	Name	Description
DRUG	Tigulixostat	300 mg oral dose
DRUG	Theophylline	400 mg oral dose

Timeline

• Start date: 2023-10-31
• Primary completion: 2023-11-13
• Completion: 2023-11-30
• First posted: 2024-01-03
• Last updated: 2024-01-03

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study