NCT04801745

Vegan Diet, Amla Fruits and Uric Acid

Effects of a Healthy Vegan Diet Vs. Low Purine Diet, with or Without Amla Fruits (Emblica Officinalis) on Hyperuricemia and Other Cardiometabolic Risk Factors: a Randomized Two-by-two Factorial Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 102 (actual)
• Sponsor: Fu Jen Catholic University · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

This is an intervention study aiming to test the effectiveness of a vegan diet, My Plate with low purine choices, and amla fruits on uric acid and other cardiometabolic risk factors in individuals with high serum uric acid levels.

Detailed description

Ninety-two participants with hyperuricemia will be randomly assigned to one of these 4 diet interventions: (1) vegan, (2) vegan with amla fruits, (3) my plate-low purine, (4) my plate-low purine with amla fruits. During the 3 months intervention phase, participants will attend group lessons and individual nutrition counseling sessions to assist adherence to the diet. At baseline, end of 3 months, and 1 year, participants will be measured on uric acid and other cardiometabolic risk factors, and some nutritional markers. Amla fruits powder, and some foods encouraged in each dietary arm will be provided to enhance adherence during the 3 months intervention phase.

Conditions

• Hyperuricemia
• Diet, Healthy
• Cardiometabolic Syndrome

Interventions

Type	Name	Description
OTHER	Healthy vegan diet	Participants will attend group lessons and individual nutrition counseling to help them adopt a healthy vegan diet.
OTHER	My Plate - Low Purine	Participants will attend group lessons and individual nutrition counseling to help them adopt a balanced diet in accordance with my plate, and emphasis on choosing low purine options from the protein food groups.
OTHER	Amla fruits	Participants will be provided with powdered amla fruits, and will be instructed to take 3g per day.

Timeline

• Start date: 2021-03-20
• Primary completion: 2024-01-30
• Completion: 2024-01-30
• First posted: 2021-03-17
• Last updated: 2024-10-03

Locations

1 site across 1 country: Taiwan