| Not Yet Recruiting | A Clinical Study on the Effect of Massaging Tian Tu Acupoint on Coughing After Esophageal Surgery NCT07518680 | Shanghai Zhongshan Hospital | N/A |
| Recruiting | Proximal Versus Total Gastrectomy for Locally Advanced Siewert Type II-III Gastroesophageal Junction Cancer NCT07482566 | Nurettin Şahin | N/A |
| Recruiting | A Study of LY4337713 in Participants With FAP-Positive Solid Tumors NCT07213791 | Eli Lilly and Company | Phase 1 |
| Recruiting | Omega-3 Fatty Acids With PD-1 Inhibitors in Advanced Esophageal Cancer NCT07272382 | Fudan University | N/A |
| Not Yet Recruiting | Tranilast Vs. Steroids to Prevent Esophageal Stricture (TAPES) After Endoscopic Resection for Superficial Neop NCT06643689 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 2 |
| Enrolling By Invitation | Luso-Cor Stent Compared to Other Endoscopic Techniques for Management of Fistulas and Anastomotic Dehiscences( NCT06862479 | Unidade Local de Saúde Santa Maria | — |
| Recruiting | Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants NCT06469944 | Merck Sharp & Dohme LLC | Phase 1 / Phase 2 |
| Recruiting | Diagnosis of Multiple Cancer and Monitoring of Minimal Residual Tumors After Treatment Using Blood and High-Se NCT07035587 | Yonsei University | — |
| Recruiting | Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker- NCT06445972 | Merck Sharp & Dohme LLC | Phase 1 / Phase 2 |
| Withdrawn | Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as A NCT05898828 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Recruiting | A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer NCT06380816 | Cancer Research UK | Phase 1 / Phase 2 |
| Recruiting | Fruquintinib in Combination With Tislelizumab Followed by Radiotherapy in Esophageal Squamous Cell Carcinoma NCT06646588 | Hebei Medical University Fourth Hospital | Phase 2 |
| Recruiting | Evaluate the Efficacy of Adding Intraluminal Brachytherapy After CCRT for Local-regional Thoracic Esophageal C NCT06365866 | Taipei Veterans General Hospital, Taiwan | N/A |
| Recruiting | PD-1 Inhibitor Plus Chemotherapy With or Without Radiotherapy in Patients With Metastatic Esophageal Cancer NCT06086457 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Phase 3 |
| Completed | Esophageal Cancer Multimodal Prehabilitation Study NCT06027515 | Massachusetts General Hospital | N/A |
| Recruiting | Camrelizumab Combined With Chemoradiotherapy in Advanced Esophageal Cancer. NCT05624099 | Fujian Cancer Hospital | Phase 2 |
| Recruiting | Effects of Bright-light Exposure Combined With Specific Exercise Training (BEST) Program in Patients With Canc NCT05875870 | Taipei Veterans General Hospital, Taiwan | N/A |
| Recruiting | HTL0039732 in Participants With Advanced Solid Tumours NCT05944237 | Cancer Research UK | Phase 1 / Phase 2 |
| Recruiting | Comparative Study Between (FC-SEMS) and (PC-SEMS) in the Palliation of Dysphagia Due to Malignant Neoplasm of NCT06070376 | Instituto do Cancer do Estado de São Paulo | N/A |
| Recruiting | Comparison of 0.4% Hyaluronic Acid Solution Versus Hydroxyethylamide Solution in Submucosal Endoscopic Resecti NCT06077981 | Instituto do Cancer do Estado de São Paulo | N/A |
| Completed | A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma NCT06381583 | City of Hope Medical Center | — |
| Unknown | Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow NCT05591053 | Activ Surgical | N/A |
| Recruiting | The Australia and New Zealand Multicentre Upper Gastrointestinal Endoscopic Tissue Resection Study NCT05804331 | Western Sydney Local Health District | — |
| Recruiting | Rehabilitation and Recovery for Persons with Esophageal or Gastric Cancer NCT05698992 | Region Skane | — |
| Unknown | Tranexamic Acid During Upper GI Endoscopic Resection Procedures NCT05688020 | Assaf-Harofeh Medical Center | Phase 4 |
| Unknown | [68Ga]Ga-ABY-025 PET for Quantification of HER2-status in Solid Tumors NCT05619016 | Karolinska University Hospital | Phase 2 |
| Completed | KCNA3 and OTOP2 Gene Methylation Combined Detection Kit (Fluorescent PCR Method) NCT05680077 | Wuhan Ammunition Life-tech Co., Ltd | — |
| Recruiting | Anlotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma Patient NCT05252078 | Jiangxi Provincial Cancer Hospital | Phase 2 |
| Unknown | Angiogenesis Inhibitor Plus Anti-PD-1/PD-L1 Antibody in Advanced Esophageal Cancer NCT05349045 | The First Affiliated Hospital of Zhengzhou University | — |
| Terminated | Dose Escalation Study of Lithium With Oxaliplatin and Capecitabine in Advanced Oesophago-Gastric or Colorectal NCT03153280 | Cancer Trials Ireland | Phase 1 |
| Completed | MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) NCT05007106 | Merck Sharp & Dohme LLC | Phase 2 |
| Unknown | TQB2450 Solution for Injection (TQB2450)+Paclitaxel+Cisplatin ± Anlotinib in the Treatment of Esophageal Cance NCT05013697 | Henan Cancer Hospital | Phase 2 |
| Terminated | A Study of Amivantamab in Participants With Previously Treated Advanced or Metastatic Gastric or Esophageal Ca NCT04945733 | Janssen Pharmaceutical K.K. | Phase 2 |
| Unknown | PD-1 Inhibitor Combined With Neoadjuvant Chemotherapy in Subjects With Resectable Locally Advanced Thoracic Es NCT05007145 | Fujian Cancer Hospital | Phase 2 |
| Completed | Report of the Survival Outcomes of Patients With Esophageal Cancer After Definitive Radiotherapy in China NCT05194371 | Chinese Academy of Medical Sciences | — |
| Unknown | Thromboprophylaxis in Oesophageal Cancer Patients NCT05067153 | University of Aarhus | Phase 4 |
| Recruiting | Endoscopic Resection of Gastrointestinal Neoplasms NCT04780256 | Azienda USL Reggio Emilia - IRCCS | — |
| Terminated | A Study of SGN-STNV in Advanced Solid Tumors NCT04665921 | Seagen Inc. | Phase 1 |
| Recruiting | Effect of NST Whole-course Nutritional Management on Nutritional Status and Adverse Reactions in Esophageal Ca NCT05800054 | The First Affiliated Hospital with Nanjing Medical University | N/A |
| Unknown | Prevalence of Sub-epithelial Lesions Among Patients Undergoing EGDs in Egypt NCT04622098 | Kafrelsheikh University | — |
| Recruiting | Effects of Preoperative Enteral Immunonutrition for Esophageal Cancer Patients Given Neoadjuvant Chemoradiothe NCT04513418 | Hecheng Li M.D., Ph.D | Phase 3 |
| Completed | Tissue Oxygen Saturation for Esophagectomy NCT04973046 | Shizuoka Cancer Center | — |
| Terminated | A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persi NCT04510285 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Unknown | Non-curative ESDs: Assessing the Rates and Risk Factors for Residual Neoplasia NCT04484311 | Universidade do Porto | — |
| Unknown | Health and Employment After Gastro Intestinal Surgery - HEAGIS2 NCT04466631 | University of Padova | — |
| Recruiting | Metachronic Brain Metastases After Esophagectomy for Esophageal Cancer (METABREC) NCT04654975 | Universitaire Ziekenhuizen KU Leuven | — |
| Active Not Recruiting | Assessment of Response to nCRT for GEJ Cancer Using a Fully Integrated PET/MRI NCT04359732 | IRCCS San Raffaele | N/A |
| Unknown | Mediastinoscopy-assisted Transhiatal Esophagectomy Versus Thoraco-laparoscopic Esophagectomy for Esophageal Ca NCT04125849 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | N/A |
| Unknown | Microbiome Analysis in esoPhageal, PancreatIc and Colorectal CaNcer Patients Undergoing Gastrointestinal Surge NCT04189393 | Radboud University Medical Center | — |
| Completed | Health and Employment After Gastro Intestinal Surgery - HEAGIS1 NCT04466592 | University of Padova | N/A |
| Terminated | Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With NCT02859415 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Completed | Automatic Diagnosis of Early Esophageal Squamous Neoplasia Using pCLE With AI NCT04136236 | Shandong University | — |
| Completed | TreatmENT of AnastomotiC Leakage After Esophagectomy NCT03829098 | Radboud University Medical Center | — |
| Recruiting | Distribution of Lymph Node Metastases in Esophageal Carcinoma NCT03222895 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Withdrawn | First-line Esophageal Carcinoma Study With Chemo vs. Chemo Plus Pembrolizumab (MK-3475-590/KEYNOTE-590)-China NCT03881111 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Anlotinib Retrospective Study for Esophageal Cancer NCT05303740 | Feng Wang | — |
| Withdrawn | A Study of Second-line Treatment of Postoperative Recurrence and Metastasis of Esophageal Cancer Treated With NCT03787251 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Phase 2 |
| Completed | The Thoracic Peri-Operative Integrative Surgical Care Evaluation (POISE) Trial- Stage I NCT02845479 | The Canadian College of Naturopathic Medicine | Phase 3 |
| Completed | Evaluation of Ocoxin®-Viusid® in Advanced Stomach Cancer and Gastric Esophagogastric Junction NCT03549494 | Catalysis SL | Phase 2 |
| Completed | OPPOSITE: Outcome Prediction of Systemic Treatment in Esophagogastric Carcinoma NCT03429816 | University Hospital Heidelberg | N/A |
| Unknown | Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer NCT03474341 | UMC Utrecht | — |
| Completed | Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's Oesophagus NCT03388047 | University of Cambridge | N/A |
| Unknown | Radiotherapy With or Without Concurrent Chemotherapy for Limited Lymphatic Metastasis of Esophageal Cancer - 3 NCT03308552 | Chinese Academy of Medical Sciences | Phase 3 |
| Terminated | Metabolomic and BH3 Profiling of Esophageal Cancers: Identification of Novel Assessment Methods of Treatment R NCT03223662 | National Cancer Institute (NCI) | Phase 2 |
| Completed | A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreat NCT03261947 | Millennium Pharmaceuticals, Inc. | Phase 2 |
| Unknown | Neoadjuvant Anti-PD-1 Antibody SHR-1210 and Radiation in Resectable Esophageal Squamous Cell Carcinoma NCT03200691 | Hangzhou Cancer Hospital | Phase 2 |
| Completed | First-line Esophageal Carcinoma Study With Pembrolizumab Plus Chemo vs. Chemo (MK-3475-590/KEYNOTE-590) NCT03189719 | Merck Sharp & Dohme LLC | Phase 3 |
| Unknown | Neoadjuvant Chemotherapy Followed by Preoperative Chemoradiation in Resectable Squamous-cell Esophageal Cancer NCT03579004 | Mona Frolova | Phase 2 |
| Completed | Efficacy and Safety of Apatinib for Recurrent or Metastatic Esophageal Squamous Cell Carcinoma NCT03274011 | Fudan University | Phase 2 |
| Completed | Combination of Radiation Therapy and Anti-PD-1 Antibody SHR-1210 in Treating Patients With Esophageal Cancer NCT03187314 | Hangzhou Cancer Hospital | Phase 2 |
| Unknown | Endoscopic Resection Multicenter Registry NCT03065257 | Weill Medical College of Cornell University | — |
| Completed | Gravity Assisted Technique for Esophageal Endoscopic Submucosal Dissection (ESD) NCT04547881 | Baylor College of Medicine | — |
| Unknown | Combination of Radiation Therapy and Peptide Specific CTL Therapy in Treating Patients With Esophageal Cancer NCT03011255 | Shixiu Wu | Phase 2 |
| Terminated | Early Detection of Esophageal Cancer NCT00341523 | National Cancer Institute (NCI) | — |
| Unknown | Long-term Outcomes of Superficial Esophageal Squamous Cell Carcinoma NCT02908204 | Shanghai Zhongshan Hospital | — |
| Terminated | A Trial of CMNa Combined With Preoperatie Concurrent Chemoradiotherapy for Locally Advanced ESCC NCT02721550 | Shandong Cancer Hospital and Institute | Phase 4 |
| Unknown | Addition of Enoxaparin to Neoadjuvant Chemoradiation of Esophageal Cancer NCT03254511 | Mashhad University of Medical Sciences | Phase 2 |
| Terminated | A Trial of CMNa Combined With Concurrent Chemoradiotherapy for Locally Recurrent ESCC NCT02721576 | Shandong Cancer Hospital and Institute | Phase 4 |
| Unknown | Simultaneous Integrated Boost Radiotherapy and Concurrent Nimotuzumab or Chemotherapy for Esophageal Carcinoma NCT02858206 | Chinese Academy of Medical Sciences | Phase 2 |
| Recruiting | Barrett's Esophagus and Esophageal Adenocarcinoma, Searching for Reliable Diagnostic RNA Plasma-based Biomarke NCT05688176 | University Hospital, Ghent | — |
| Terminated | Tumor Hypoxia With HX4 PET in Several Diseases NCT02584400 | Maastricht Radiation Oncology | Phase 2 |
| Completed | A Trial of CMNa Combined With Definitive Concurrent Chemoradiotherapy for Locally Advanced ESCC NCT02721563 | Shandong Cancer Hospital and Institute | Phase 4 |
| Completed | Influence of Esophageal Washout on Local Carcinoma Recurrence After Curative Resection NCT02676791 | Technische Universität Dresden | N/A |
| Completed | Analysis of Risk Factors of Postoperative Pulmonary Infection in Patients With Esophageal Cancer NCT05740852 | Xijing Hospital | — |
| Unknown | Adjuvant Therapies or Surgery Alone for High Risk pN0 Esophageal Cancer NCT02891083 | Shanghai Chest Hospital | Phase 3 |
| Unknown | Oral Prednisolone to Prevent Esophageal Stricture After RFA for Long-segment Esophageal Neoplasia NCT05768282 | E-DA Hospital | Phase 4 |
| Completed | Comparison of Captivator Tissue Cassettes vs. no Cassettes for Endoscopic Mucosal Resection in Esophageal Carc NCT02911363 | AdventHealth | N/A |
| Unknown | Autologous Tumor Tissue Antigen-sensitized DC-CIK Cells Combined With Chemotherapy for Esophageal Cancer NCT02644863 | Shenzhen Hornetcorn Bio-technology Company, LTD | Phase 2 |
| Completed | Endoscopic Evaluation After Esophagectomy NCT02703142 | Nagasaki University | — |
| Completed | Nutritional Route In Esophageal Resection Trial II NCT02378948 | Catharina Ziekenhuis Eindhoven | N/A |
| Recruiting | Mayo Clinic Upper Digestive Disease Survey NCT02530983 | Mayo Clinic | — |
| Unknown | Chronomodulated Chemotherapy Followed by Concurrent Chemo-radiotherapy With IMRT in the Treatment of Advanced NCT02937519 | Guiyang Medical University | Phase 2 |
| Completed | Endoscopic Evaluation for Predicting the Complications Related to Gastric Conduit After Esophagectomy NCT02937389 | Nagasaki University | — |
| Completed | Regorafenib in Combination With Paclitaxel in Advanced Oesophagogastric Carcinoma NCT02406170 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Phase 1 / Phase 2 |
| Unknown | Impact of Perioperative Physical Activity on Postoperative Pulmonary Complications and Quality of Life Among E NCT03231462 | Samsung Medical Center | — |
| Unknown | Feasibility Study of Fiducial Markers in Oesophageal Cancer NCT02403050 | NHS Greater Glasgow and Clyde | — |
| Completed | The Effect of Satiety Gut Hormone Modulation on Appetitive Drive After Upper Gastrointestinal Surgery NCT02381249 | St. James's Hospital, Ireland | N/A |
| Completed | Longitudinal Assessment of Gut Hormone Secretion Following Upper Gastrointestinal Surgery for Cancer NCT02385630 | St. James's Hospital, Ireland | N/A |
| Completed | PReoperative Chemoradiation (Paclitaxel-carboplatin or FOLFOX) for Resectable Esophageal and Junctional Cancer NCT02359968 | Centre Oscar Lambret | Phase 2 |
| Terminated | Endoscopic Injection of Mitomycin C for the Treatment of Pharyngoesophageal Stenosis NCT03540953 | Fauze Maluf Filho | N/A |
| Completed | Simultaneous Integrated Boost Radiotherapy and Concurrent Chemotherapy for Locally Advanced Esophageal Carcino NCT02429622 | Chinese Academy of Medical Sciences | Phase 1 / Phase 2 |
| Completed | Irreversible Electroporation(IRE) For Unresectable Esophageal Neoplasms NCT02430701 | Fuda Cancer Hospital, Guangzhou | N/A |
| Completed | Cardiopulmonary Effects of Intrathoracic Pressure Overshoot During Carbon Dioxide Insufflation in Thoracoscopi NCT02330536 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Unknown | Irinotecan Plus S1 Versus S1 in Patients With Previously Treated Advanced Esophageal Cancer: ESWN 01 Trial NCT02319187 | Chinese Academy of Medical Sciences | Phase 3 |
| Unknown | Phase II/III Study Compare Adjuvant Chemoradiotherapy, Radiotherapy and Surgery Alone for Esophageal Carcinoma NCT02279134 | Zefen Xiao | Phase 2 / Phase 3 |
| Unknown | The Role of Different Cycles of Chemotherapy（Capecitabine-oxaliplatin） in Esophageal Chemoradiotherapy NCT02604615 | The First Affiliated Hospital of Henan University of Science and Technology | Phase 3 |
| Completed | Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy NCT02284802 | Fauze Maluf Filho | N/A |
| Completed | Innovative MRI Techniques to Improve Treatment Stratification of Patients With Esophageal Cancer NCT02253602 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Completed | Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer NCT02128243 | AIO-Studien-gGmbH | Phase 2 |
| Unknown | Study Assessing the Effects of Chemotherapy in Advanced Esophagogastric Adenocarcinoma NCT02177552 | Rigshospitalet, Denmark | Phase 2 |
| Completed | A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab NCT02013154 | Leap Therapeutics, Inc. | Phase 1 |
| Completed | Identification of Biomarkers for Prediction of Response or Resistance Against Target Therapy in Gastric Cancer NCT02305043 | University of Leipzig | — |
| Unknown | Comparison of Ivor Lewis and Tri-incision Approaches for Patients With Esophageal Cancer NCT02017002 | National Taiwan University Hospital | N/A |
| Completed | Pronase Improves Efficacy of Chromoendoscopy Screening on Esophageal Cancer NCT02030769 | Xijing Hospital of Digestive Diseases | N/A |
| Unknown | Effect of Neck Flexion on Esophagogastric Anastomotic Leakage After MIE NCT02418052 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Completed | Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer NCT02385617 | St. James's Hospital, Ireland | N/A |
| Completed | The Predictive Value of CT-PET in Esophageal Cancer NCT02385604 | St. James's Hospital, Ireland | — |
| Completed | Combination Chemotherapy in Treating Patients With Advanced Stomach, Gastroesophageal, or Esophageal Cancer NCT01928290 | Washington University School of Medicine | Phase 2 |
| Completed | Removal of the Evolution® Esophageal Stent - Fully Covered NCT01900691 | Cook Group Incorporated | N/A |
| Completed | Esophagectomy:Three-field Versus Two-field Lymphadenectomy (ECTOP-2002) NCT01807936 | Fudan University | N/A |
| Completed | A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer NCT02182804 | King Chulalongkorn Memorial Hospital | N/A |
| Completed | Phase I Platinum Based Chemotherapy Plus Indomethacin NCT01719926 | UMC Utrecht | Phase 1 |
| Completed | Study of Simultaneous Modulated Accelerated Radiation Therapy Concurrent With Chemotherapy to Treat Esophageal NCT01670409 | Chuangzhen Chen | Phase 2 |
| Unknown | Radiation Dose Study of Concurrent Chemoradiotherapy With Cisplatin Plus Fluorouracil in Oesophageal Cancer NCT01646853 | Simcere Pharmaceutical Co., Ltd | N/A |
| Completed | Home Jejunostomy Feeding Following Esophagectomy/Gastrectomy NCT01870817 | University Hospitals, Leicester | N/A |
| Unknown | Impact of Gastric Tube Reconstruction Widths on Quality of Life for Esophagogastric Cancers NCT01911832 | West China Hospital | Phase 3 |
| Unknown | Docetaxel and S-1 for Advanced Esophageal Cancer NCT01693432 | Hallym University Medical Center | Phase 2 |
| Terminated | Endoscopic Resection or Ablation for Patients With Dysplasia or Cancer Requiring Treatment of Barrett's Esopha NCT01572987 | Midwest Biomedical Research Foundation | N/A |
| Withdrawn | Efficacy Study on the Transfer of Adenovirus With the CD40 Ligand Gene (AdcuCD40L) to Patients With Esophageal NCT00504322 | Weill Medical College of Cornell University | Phase 1 / Phase 2 |
| Completed | The Impact of Different Anticoagulant Therapy on Hemorrhage and Coagulation After Thoracic Surgery NCT01267305 | Shanghai Zhongshan Hospital | N/A |
| Unknown | A Trial to Compare Preoperative Chemoradiation and Surgery Versus Surgery Alone in Squamous Cell Carcinoma of NCT01151839 | All India Institute of Medical Sciences | N/A |
| Completed | Esophagectomy: Sweet Versus Ivor-Lewis (ESVIL) (ECTOP-2001) NCT01047111 | Fudan University | N/A |
| Unknown | Endoscopic Submucosal Dissection in Upper Gastrointestinal Canal With HybridKnife NCT01185483 | Odense University Hospital | — |
| Completed | A Study of BMS-833923 With Cisplatin and Capecitabine in Inoperable, Metastatic Gastric, Gastroesophageal, or NCT00909402 | Bristol-Myers Squibb | Phase 1 |
| Completed | Quality of Life in Neoadjuvant Versus Adjuvant Therapy of Esophageal Cancer Treatment Trial NCT00907543 | Richard Malthaner | N/A |
| Terminated | A Phase III Study of En Bloc Versus Non-En Bloc Esophagectomy in Esophageal Cancer NCT00760604 | Weill Medical College of Cornell University | Phase 3 |
| Unknown | Lifting of Gastric Tube Through Trans-substernal Versus Trans-esophageal Bed Path in MIE NCT02309619 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Unknown | Endoscopic-vacuum Assisted Closure of Intrathoracic Postsurgical Leaks NCT00876551 | Hannover Medical School | N/A |
| Terminated | The Study of Barrett's Esophagus: What Are the Factors of Progression NCT00586404 | Midwest Biomedical Research Foundation | — |
| Terminated | Perioperative Nutrition in Upper Gastrointestinal (GI) Cancer Surgery NCT00560846 | Dan Azagury | N/A |
| Completed | Study of PEP02, Irinotecan or Docetaxel in Gastric or Gastroesophageal Junction Adenocarcinoma NCT00813072 | PharmaEngine | Phase 2 |
| Completed | PET-CT Based Radiotherapy in Esophageal Cancer Patients NCT01156831 | Maastricht Radiation Oncology | — |
| Completed | Hybrid-everted Versus Hand-sewn or Stapled Esophagogastrostomy in Prevention of Anastomotic Stricture NCT01139229 | Sichuan University | N/A |
| Completed | Pharmacogenomically Selected Treatment for Gastric and Gastroesophageal Junction (GEJ) Tumors NCT00515216 | Vanderbilt University | Phase 2 |
| Completed | Postoperative Chemoradiation in Patients With Node-positive Esophageal Squamous Cell Carcinoma NCT02446574 | Chinese Academy of Medical Sciences | Phase 1 / Phase 2 |
| Terminated | Erlotinib and Avastin in Patients With Cancer of the Esophagus or Gastroesophageal Junction NCT00442507 | Washington University School of Medicine | Phase 2 |
| Completed | Oxaliplatin, Capecitabine and Avastin for Metastatic Esophagogastric Adenocarcinoma NCT00447330 | Duke University | Phase 2 |
| Completed | Study of Docetaxel, Cisplatin, and Fluorouracil (Modified DCF) With Bevacizumab in Patients With Unresectable NCT00390416 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Terminated | A Phase II Study of Pemetrexed and Carboplatin in the Treatment of Esophageal Cancer NCT00383266 | Washington University School of Medicine | Phase 2 |
| Terminated | Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced Esophageal Cancer NCT00368329 | Stanford University | Phase 1 |
| Terminated | Study of Cryotherapy Treatment of Barrett's Esophagus and Early Esophageal Cancer NCT00321958 | University of Maryland, Baltimore | — |
| Completed | Safety and Efficacy of Neoadjuvant Radiochemotherapy in Adenocarcinoma of the Gastric-oesophageal Junction NCT00374985 | Johannes Gutenberg University Mainz | Phase 1 / Phase 2 |
| Completed | Intravenous NTG to Preserve Gastric Microcirculation During Gastric Tube Reconstruction NCT00335010 | Erasmus Medical Center | N/A |
| Completed | Study of Irinotecan and Docetaxel in Patients With Metastatic or Unresectable Gastric or Gastroesophageal Junc NCT00183872 | University of Southern California | Phase 2 |
| Completed | Endoscopic Resection of Early Esophageal Tumors in the Context of Cirrhosis or Portal Hypertension NCT04994548 | Central Hospital, Nancy, France | — |
| Withdrawn | Safety Study on the Transfer of the CD40 Ligand Gene (AdcuCD40L) to Patients With Esophageal Carcinoma NCT00328887 | Weill Medical College of Cornell University | Phase 1 |
| Terminated | Depsipeptide/Flavopiridol Infusion for Cancers of the Lungs, Esophagus, Pleura, Thymus or Mediastinum NCT00094978 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Study Comparing Radiochemotherapy With Folfox 4 Regimen or 5FU-Cisplatin in Patients With Inoperable Esophagea NCT00160030 | Sanofi | Phase 2 |
| Completed | Tezacitabine With or Without 5-Fluorouracil (5-FU) for Advanced Esophageal Cancer or Gastric Cancer NCT00054873 | Chiron Corporation | Phase 2 |
| Completed | Weekly Cisplatin/Irinotecan and Radiotherapy in Patients With Locally Advanced Esophageal Cancer: Phase II Tri NCT00213486 | University Hospital, Rouen | Phase 2 |
| Suspended | Study of T900607-Sodium in Subjects With Previously Treated Gastric Cancer or Adenocarcinoma of the Esophagus NCT00048529 | Tularik | Phase 2 |
| Terminated | RCT on the Combined Modality Treatment of Squamous Cell Carcinoma of the Esophagus NCT00559351 | Ministry of Scientific Research and Information Technology, Poland | Phase 3 |
| Completed | Magnetic-Targeted Doxorubicin in Treating Patients With Cancer Metastatic to the Liver NCT00041808 | FeRx | Phase 1 / Phase 2 |
| Completed | Safety and Efficacy of G17DT Immunogen in the Treatment of Gastric and Gastroesophageal Cancer NCT00042510 | Cancer Advances Inc. | Phase 2 |
| Terminated | A Trial of Chemotherapy Before and After Surgery for Stage II,III Esophageal Squamous Cell Carcinoma NCT00190554 | Japan Clinical Oncology Group | Phase 3 |
| Completed | Docetaxel and Carboplatin Followed by Oral Capecitabine, Docetaxel and Radiation for Esophageal Cancer NCT00153881 | Dartmouth-Hitchcock Medical Center | Phase 1 |
| Completed | Oxaliplatin in Esophagus Cancer (Advanced) 1st Line NCT00259402 | Sanofi | Phase 2 |
| Unknown | A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Solid Malignancies NCT00057395 | Aronex Pharmaceuticals | Phase 1 / Phase 2 |