NCT02937389

Endoscopic Evaluation for Predicting the Complications Related to Gastric Conduit After Esophagectomy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Nagasaki University · Academic / Other
• Sex: All
• Age: 20 Years – 84 Years
• Healthy volunteers: Not accepted

Summary

Gastric conduit ischemia or anastomotic breakdown after esophagectomy with cervical esophagogastrostomy often cause severe complications, such as leakage, necrotic organs, and strictures. Thus, the purpose of this study is the safety and efficacy of endoscopic evaluation about reconstructive organs after esophagectomy. The investigators evaluate endoscopic predictions using classifications in acute phase after esophagogastrostomy.

Detailed description

The development and improvement of thoracoscopic esophagectomy (TE) reduced the severe pulmonary complication after esophagectomy. However, the postoperative complications relative to gastric conduit reconstruction are still common issues after esophagectomy. The ischemia of the proximal portion of the graft predisposes these patients to a high incidence of anastomotic complications after esophagectomy. Less commonly, severe graft ischemia can lead to transmural necrosis. Thus, early diagnosis of ischemic reaction may provide the suitable postoperative management and therapeutic intervention to prevent leakage, strictures and necrosis. Thus, the purpose of this study is the safety and efficacy of endoscopic evaluation about reconstructive organs after esophagectomy. The investigators evaluate endoscopic predictions using classifications in acute phase after esophagogastrostomy.

Conditions

• Esophageal Neoplasms
• Constriction
• Anastomotic Leak
• Ischemia

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Patients after esophagectomy	Endoscopic examinations are performed at 1 and 8 postoperative days. Endoscopic examination is added when abnormal findings are demonstrated.

Timeline

• Start date: 2015-05-01
• Primary completion: 2018-11-01
• Completion: 2019-11-01
• First posted: 2016-10-18
• Last updated: 2023-04-05

Locations

1 site across 1 country: Japan