Trials / Sponsors / Leap Therapeutics, Inc.
Leap Therapeutics, Inc.
Industry · 11 registered clinical trials.
| Status | Trial | Phase | Started |
|---|---|---|---|
| Completed | Phase 2 Study of DKN-01 in Colorectal Cancer Colorectal Cancer, Colorectal Adenocarcinoma, Colo-rectal Cancer | Phase 2 | 2022-08-30 |
| Terminated | A Study of DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Gastric Cancer, Gastric Adenocarcinoma, GastroEsophageal Cancer | Phase 2 | 2020-07-29 |
| Terminated | A Dose Escalation and Expansion Study of TRX518 in Combination With Cyclophosphamide Plus Avelumab in Advanced Solid Tumors, Advanced Triple Negative Breast Cancer, Advanced Hormone Receptor Positive/Endocrine Refractory Breast Cancer | Phase 1 | 2019-05-20 |
| Completed | A Study of DKN-01 as a Monotherapy or in Combination With Paclitaxel in Patients With Recurrent Epithelial End Endometrial Cancer, Uterine Cancer, Ovarian Cancer | Phase 2 | 2018-03-05 |
| Completed | Phase 1 Open-label Study of TRX518 Monotherapy and TRX518 in Combination With Gemcitabine, Pembrolizumab, or N Solid Tumors | Phase 1 | 2016-01-01 |
| Completed | Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Carcinoma of Intrahepatic and Extra-hepatic Biliary System, Carcinoma of Gallbladder, Bile Duct Cancer | Phase 1 | 2015-06-01 |
| Completed | A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab Esophageal Neoplasms, Adenocarcinoma of the Gastroesophageal Junction, Gastroesophageal Cancer | Phase 1 | 2014-05-05 |
| Completed | A Study of DKN-01 and Lenalidomide/Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma Multiple Myeloma | Phase 1 | 2013-05-01 |
| Completed | A Study of DKN-01 in Multiple Myeloma or Advanced Solid Tumors Multiple Myeloma, Solid Tumors, Non-Small Cell Lung Cancer | Phase 1 | 2012-01-01 |
| Completed | Trial of TRX518 (Anti-GITR mAb) in Stage III or IV Malignant Melanoma or Other Solid Tumors Unresectable Stage III or Stage IV Malignant Melanoma or Other Solid Tumor Malignancies | Phase 1 | 2010-10-01 |
| No Longer Available | Expanded Access Use of DKN-01 for the Treatment of Advanced Solid Tumors Esophageal Neoplasm, Adenocarcinoma of the Gastroesophageal Junction, GastroEsophageal Cancer | — | — |