NCT00907543

Quality of Life in Neoadjuvant Versus Adjuvant Therapy of Esophageal Cancer Treatment Trial

Prospective Randomized Phase III Trial Comparing Preoperative Chemoradiation Therapy (Cisplatin, 5-FU and Radiotherapy Followed by Surgery) to Surgery Followed by Postoperative Chemoradiation (Cisplatin, Epirubicin, 5-FU, Radiotherapy) for Esophageal Cancer

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 96 (actual)
• Sponsor: Richard Malthaner · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the results of preoperative chemotherapy and radiation followed by surgery to surgery followed by postoperative chemotherapy and radiation for esophageal cancer.

Detailed description

Patients will be randomized to neo-adjuvant or adjuvant treatment. Quality of life questionnaires will be completed every 2 months up to 1 year.

Conditions

• Esophageal Neoplasms

Interventions

Type	Name	Description
OTHER	Preoperative treatment of chemotherapy and radiation	Cisplatin + 5FU with concurrent radiation followed by surgery
OTHER	Postoperative treatment of chemotherapy and radiation	Surgery followed by cisplatin + 5FU + epirubicin as indicated by pathological stage with extended beam radiation

Timeline

• Start date: 2009-04-01
• Primary completion: 2018-12-31
• Completion: 2018-12-31
• First posted: 2009-05-22
• Last updated: 2019-03-06

Locations

1 site across 1 country: Canada