NCT04780256

Endoscopic Resection of Gastrointestinal Neoplasms

Retrospective Study of Efficacy and Safety of the Endoscopic Removal of Cancerous and Precancerous Lesions of the Upper and Lower Digestive Tract

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: Azienda USL Reggio Emilia - IRCCS · Other Government
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The study aims to retrospectively investigate the endoscopic resection procedures of cancerous and precancerous lesions of the upper and lower digestive tract in order to evaluate the efficacy and safety outcomes and to compare different resection techniques. In particular, the resection techniques investigated will be mucosectomy, en bloc and piecemeal, endoscopic submucosal dissection (ESD) and its variants, full-thickness resection. The anatomical districts involved will be the esophagus, stomach, duodenum, colon and rectum.

Conditions

• Endoscopic Mucosal Resection
• Endoscopic Submucosal Dissection
• Gastric Neoplasm
• Colonic Neoplasms
• Esophageal Neoplasms
• Duodenal Neoplasms

Interventions

Type	Name	Description
PROCEDURE	Endoscopic resection	The endoscopic resection is the procedure that allows to remove cancerous or precancerous conditions of digestive tract. Endoscopic resection can be preformed by several techniques: 1. Endoscopic mucosal resection (EMR): it allows to remove mucosal lesions 2. Endoscopic submucosal dissection: it allows to remove mucosal lesions that involved submucosal layer and large lesions 3. Full-thickness resection: it allows to remove infiltrating lesions by the resection of a little piece of the entire gastrointestinal wall

Timeline

• Start date: 2021-03-15
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2021-03-03
• Last updated: 2025-10-03

Locations

1 site across 1 country: Italy