NCT04994548

Endoscopic Resection of Early Esophageal Tumors in the Context of Cirrhosis or Portal Hypertension

Endoscopic Resection of Early Esophageal Tumors in the Context of Cirrhosis or Portal Hypertension: a Multicenter Observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 112 (actual)
• Sponsor: Central Hospital, Nancy, France · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Cirrhotic patients may be at high risk for esophageal cancer. Endoscopic resection is the standard treatment for superficial tumors. However, cirrhosis might be associated with upper gastrointestinal bleeding, particularly in case of portal hypertension or coagulopathy. This study aims to assess safety, efficacy and methods to prevent potential complications in cirrhosis or portal hypertension context for esophageal endoscopic resection. This retrospective multicentric French-Belgian study includes all consecutive patients with cirrhosis or portal hypertension who underwent esophageal endoscopic resection from January 2005 to 2021.

Conditions

• Esophageal Neoplasms
• Cirrhosis
• Portal Hypertension

Interventions

Type	Name	Description
PROCEDURE	Endosocpic resection of early esophageal tumor	under general anesthesia, by mucosectomy or endoscopic submucosal dissection

Timeline

• Start date: 2005-01-01
• Primary completion: 2005-02-03
• Completion: 2021-03-31
• First posted: 2021-08-06
• Last updated: 2021-08-06