| Not Yet Recruiting | Fiber-Optic Navigation During TIPS Creation: A Prospective Pilot Study NCT07470515 | Medical University Innsbruck | N/A |
| Recruiting | Exploration of Systemic and Portal Hemostasis in Patients Undergoing Transjugular Intrahepatic Portosystemic S NCT07439939 | Assistance Publique - Hôpitaux de Paris | — |
| Recruiting | Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis NCT07521332 | Asian Institute Of Medical Sciences | Phase 4 |
| Not Yet Recruiting | Non-invasive Predictors of Esophageal Varices and Their Correlation to Upper Endoscopic Findings NCT07464522 | Assiut University | — |
| Not Yet Recruiting | Optimizing Endoscopic and Interventional Treatment for Portal Hypertensive Bleeding NCT07502729 | Shanghai Zhongshan Hospital | — |
| Not Yet Recruiting | Cirrhotic and Non-cirrhotic Patients With Clinically Significant Portal Hypertension NCT07405749 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Not Yet Recruiting | Liver Cirrhosis Complicated by Clinically Significant Portal Hypertension NCT07365709 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Not Yet Recruiting | Treatment Outcomes for Portal Hypertension Esophageal and Gastric Varices NCT07358663 | Shanghai Zhongshan Hospital | — |
| Not Yet Recruiting | The Feasibility, Safety, and Efficacy of EUS-Guided PSE: A Cohort Study NCT07354789 | Qilu Hospital of Shandong University | N/A |
| Not Yet Recruiting | TACE Combined With Tislelizumab, Lenvatinib, and Carvedilol for Unresectable HCC With Cirrhotic Portal Hyperte NCT07350070 | Tongji Hospital | Phase 2 |
| Not Yet Recruiting | Effects of Terlipressin and Somatostatin on Portal Pressure in Patients Undergoing Living Donor Liver Transpla NCT07304466 | Istanbul Medipol University Hospital | N/A |
| Recruiting | Construction of a Portal Hypertension Biobank NCT07419724 | Shanghai Zhongshan Hospital | — |
| Recruiting | Effect of Handgrip Strength on Portal Vein Hemodynamics in Patients With Liver Cirrhosis NCT07116096 | Shanxi Provincial People's Hospital | N/A |
| Recruiting | A Study to Evaluate Splenectomy on Debridement for Acute Necrotizing Pancreatitis With Pancreatic Sinistral Po NCT07080697 | Zhejiang University | N/A |
| Not Yet Recruiting | A Study to Predict Recompensation in Patients With Decompensated Cirrhosis Using Spleen Stiffness and Simple B NCT07087041 | Beijing Friendship Hospital | — |
| Not Yet Recruiting | Clinical Study on the Selection of Endoscopic Varicose Disconnection Strategy Based on Natural Portal Shunt wi NCT06883071 | Zhejiang University | N/A |
| Not Yet Recruiting | Electromagnetic Positioning-Assisted Ultrasound Guidance in Transjugular Intrahepatic Portosystemic Shunt (TIP NCT06979622 | Nanfang Hospital, Southern Medical University | N/A |
| Recruiting | Hepatic Venous Pressure Gradient Versus Endoscopic Ultrasound-Guided Portal Pressure Gradient - Comparative An NCT07424963 | Military University Hospital, Prague | N/A |
| Recruiting | TIPS for Complicated Portal Hypertension Related to Porto-Sinusoidal Vascular Disease NCT07163689 | Centre Hospitalier Universitaire, Amiens | — |
| Recruiting | EUS-guided Portal Pressure Gradient (PPG) Measurement: a Potential Alternative to the Traditional HVPG NCT06863012 | Fundacio Privada Mon Clinic Barcelona | N/A |
| Recruiting | Early TIPS in Patients With Liver Cirrhosis and Ascites NCT06576934 | University Hospital Freiburg | N/A |
| Recruiting | Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hyper NCT06797193 | Mayo Clinic | N/A |
| Recruiting | Improve the Strategies of Endoscopic and Interventional Treatment of Gastroesophageal Hemorrhage in Portal Hyp NCT06970509 | Shanghai Zhongshan Hospital | — |
| Recruiting | Safety of Discontinuing NSBBs in Cirrhotic Patients With Managed Primary Aetiological Factors NCT06549673 | Chinese University of Hong Kong | — |
| Not Yet Recruiting | Von Willebrand Factor Levels in Patients With Liver Cirrhosis and Portal Hypertension NCT06694090 | Assiut University | — |
| Recruiting | Non-selective Beta-blocker in Compensated Advanced Chronic Liver Disease NCT06449339 | Chinese University of Hong Kong | Phase 4 |
| Unknown | Continuous Versus Bolus Infusion of Terlipressin for Portal Hypertension Related Bleeding in Liver Cirrhosis NCT03130127 | General Hospital of Shenyang Military Region | N/A |
| Recruiting | Cera™ Vascular Plug System Post-Market Clinical Follow-Up NCT06099015 | Lifetech Scientific (Shenzhen) Co., Ltd. | — |
| Recruiting | hepatomiR cACLD Study NCT06432582 | Karl Landsteiner University of Health Sciences | — |
| Not Yet Recruiting | Efficacy and Safety of Intraparenchymal Portal Vein Covered Stents in Treating Portal Hypertension and Its Com NCT06320912 | Shanghai Shenqi Medical Technology Co., Ltd | N/A |
| Not Yet Recruiting | Two-dimensional Shear Wave Elastography for Assessment of Cirrhosis and Portal Hypertension NCT06358092 | Third Affiliated Hospital, Sun Yat-Sen University | — |
| Unknown | Noninvasive Prediction of Portal Hypertension in Cirrhosis Using Sound Touch Viscoelastography NCT06316869 | First Affiliated Hospital of Wenzhou Medical University | — |
| Terminated | NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirr NCT06000748 | University of California, San Francisco | Phase 2 / Phase 3 |
| Recruiting | SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury NCT06173947 | Nanfang Hospital, Southern Medical University | — |
| Not Yet Recruiting | Preemptive TIPS for Gastric Variceal Bleeding in Patients With Cirrhosis NCT06122792 | West China Hospital | N/A |
| Not Yet Recruiting | Preemptive TIPS for Variceal Bleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis NCT06122753 | West China Hospital | N/A |
| Unknown | A Novel Imaging Based Quantitative Model-aided Detection of Portal Hypertension in Patients With Cirrhosis (CH NCT05068492 | Hepatopancreatobiliary Surgery Institute of Gansu Province | — |
| Recruiting | Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis NCT06265272 | Massachusetts General Hospital | — |
| Unknown | The Use of Endoscopic Ultrasound-Guided Portal Pressure Measurements to Guide Beta-Blocker Therapy in Patients NCT05357599 | University of Southern California | N/A |
| Unknown | Liver and Spleen Stiffness Measured by TE and 2D-SWE for Diagnosis of CSPH in Patients With cACLD NCT06147947 | Fifth Affiliated Hospital, Sun Yat-Sen University | — |
| Recruiting | Non-Invasive Portal and Hepatic Vein Pressure Estimation NCT06210178 | Leiden University Medical Center | N/A |
| Recruiting | Clinical Study of PTFE Covered Stent for Treating Portal Hypertension NCT06117735 | Enlight Medical Technologies (Shanghai) Co., Ltd | N/A |
| Unknown | Clinical,Endoscopic and Radiological Assessment of Portal Hypertension in Children With Chronic Liver Diseases NCT06097715 | Sohag University | N/A |
| Unknown | Liver and Spleen Stiffness Measured by TE and 2D-SWE for Diagnosis of GOV in Patients With cACLD NCT06144437 | Fifth Affiliated Hospital, Sun Yat-Sen University | — |
| Unknown | A Novel Spleen-dedicated Stiffness Measured by FibroScan to Evaluate Cirrhotic Portal Hypertension (CHESS2105) NCT05052892 | Hepatopancreatobiliary Surgery Institute of Gansu Province | — |
| Completed | A Pilot Trial to Test the Feasibility of Utilizing Home Blood Pressure Monitoring to Optimize the Administrati NCT05928624 | University of California, San Francisco | N/A |
| Recruiting | Direct Portal Pressure Measurement Via Endoscopic Ultrasound in Advanced Chronic Liver Disease (EVADIPP) NCT06266260 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Recruiting | Clinical Diagnosis and Pathological Spectrum of Porto-sinusoidal Vascular Disease in India NCT06054451 | Post Graduate Institute of Medical Education and Research, Chandigarh | — |
| Terminated | Achieving Portal Access With Scorpion Post-Approval Study (APASS) NCT05765253 | Argon Medical Devices | N/A |
| Active Not Recruiting | A Digital Tongue Diagnosis Model for High- and Low-risk Esophagogastroduodenal Varices in Cirrhosis NCT05979935 | Qilu Hospital of Shandong University | — |
| Enrolling By Invitation | Liver and Spleen Stiffness to Predict the Presence of Esaphageal Varices in Cirrhotic With Advanced HCC NCT06773260 | Azienda Ospedaliero Universitaria Policlinico Modena | — |
| Completed | LiveSMART Trial to Prevent Falls in Patients With Cirrhosis NCT05794555 | University of Michigan | Phase 3 |
| Active Not Recruiting | LiveSMART Trial to Prevent Falls in Patients With Cirrhosis - Supplementary Study NCT07140120 | University of Michigan | — |
| Unknown | CT-based HVPG Assessment for Predicting the Prognosis of HCC With TACE (CHANCE-CHESS 2302) NCT05704192 | Zhongda Hospital | — |
| Unknown | Impact of Clinical Evident Portal Hypertension on HCC With TACE (CHANCE-CHESS 2301) NCT05703750 | Zhongda Hospital | — |
| Completed | Acute Hemodynamic Response to Carvedilol in Children With Clinically Significant Portal Hypertension. NCT05767229 | Institute of Liver and Biliary Sciences, India | N/A |
| Unknown | Hepatic Venous Pressure Gradient and Elastography in Porto-sinusoidal Vascular Disorder NCT05719857 | Universidade Federal do Rio de Janeiro | N/A |
| Unknown | Non-invasive Diagnosis of Portal Hypertension in Cirrhosis Based on Metabolomics Technology NCT05551884 | Hepatopancreatobiliary Surgery Institute of Gansu Province | — |
| Completed | EUS-PPG vs HVPG in Portal Hypertension NCT05689268 | Hospital General Universitario de Alicante | N/A |
| Recruiting | Standard Therapy and TIPS for Moderate to High-risk Esophageal and Gastric Variceal Bleeding NCT06013670 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | N/A |
| Unknown | Carvedilol vs. Propranolol in Second Prophylaxis of Variceal Bleeding NCT05651789 | West China Hospital | N/A |
| Recruiting | Freiburg TIPS Registry NCT05782556 | University Hospital Freiburg | — |
| Recruiting | Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewal NCT05470205 | Thomas Jefferson University | Phase 3 |
| Enrolling By Invitation | The Instant Efficacy and Safety of Alverine in Decreasing Portal Hypertension: an Exploratory Pilot Study NCT05508633 | Shanghai Changzheng Hospital | Phase 2 |
| Recruiting | Zinc Supplementation to Improve Prognosis in Patients With Compensated Advanced Chronic Liver Disease. NCT06434753 | Hospital Universitari Vall d'Hebron Research Institute | Phase 3 |
| Unknown | Evaluation of EUS in Preventing Rebleeding After Endoscopic Cyanoacrylate Injection for Gastric Varices NCT05515861 | Renmin Hospital of Wuhan University | N/A |
| Recruiting | 3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension NCT05475015 | Shengjing Hospital | — |
| Unknown | Atorvastatin Use and Portal Hypertension in Patients With Hepatitis B Virus-related Liver Cirrhosis: A Randomi NCT05483894 | Samsung Medical Center | Phase 2 |
| Unknown | An AI Model Based on Smartphone-derived Multimodality Images to Evaluate Portal Hypertension in Patients With NCT05402410 | Hepatopancreatobiliary Surgery Institute of Gansu Province | — |
| Recruiting | The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis P NCT05325437 | Northern Jiangsu People's Hospital | N/A |
| Completed | Vonoprazan Efficacy to Prevent Post Variceal Band Ligation Ulcer NCT05227833 | Alexandria University | Phase 3 |
| Completed | Achieving Portal Access With Scorpion Post-Approval Study 2 NCT06856655 | Argon Medical Devices | — |
| Active Not Recruiting | Effectiveness of Treatments for Cirrhosis With Varicose Veins NCT06961474 | Shanghai Zhongshan Hospital | — |
| Completed | Portal Hypetension and Bariatric Surgery (BARIAPORTAL) NCT05653115 | Centre Hospitalier Universitaire de Nice | — |
| Unknown | Impact of Fentanyl Analgesia on the Accuracy of HVPG Measurements in Patients With Portal Hypertension NCT04724148 | Hepatopancreatobiliary Surgery Institute of Gansu Province | N/A |
| Active Not Recruiting | Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant NCT05027425 | Davendra Sohal | Phase 2 |
| Completed | Evaluation of Long Haul COVID-19 and Vaccine Immunogenicity in Patients With Liver Disease NCT05107271 | Post Graduate Institute of Medical Education and Research, Chandigarh | — |
| Completed | EUS vs TJ for Liver Biopsy and Portal Pressure Gradient Measurement NCT05118308 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Unknown | A Combined Model Based on Spleen Stiffness, Liver Stiffness and Platelets for Assessing Portal Hypertension in NCT05251272 | Hepatopancreatobiliary Surgery Institute of Gansu Province | — |
| Unknown | The Timing of Emergency Endoscopy for Esophagogastric Variceal Bleeding in Cirrhosis NCT04932200 | Renmin Hospital of Wuhan University | — |
| Unknown | The Precise Selection of Stent Diameter for Portal Hypertension Patients With TIPS NCT04421118 | First Affiliated Hospital of Zhejiang University | — |
| Active Not Recruiting | Improvement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D) NCT04863703 | Hannover Medical School | — |
| Completed | Evaluation of Minimal Hepatic Encephalopathy in Patients With Cirrhosis and Portal Hypertension NCT04807803 | IHU Strasbourg | N/A |
| Unknown | The Effect of Monitoring PVP on Clinical Outcomes in Patients With PH NCT04820166 | Nanfang Hospital, Southern Medical University | — |
| Unknown | Effect of Antiviral Therapy on HVPG in Patients With Viral Cirrhosis NCT04797910 | Nanfang Hospital, Southern Medical University | — |
| Unknown | The vPPG-detecting Software Guided Management of Cirrhotic Portal Hypertension NCT04786782 | Changqing Yang | — |
| Unknown | Ultrasound Guided Microwave Ablation of Splenomegaly in Children NCT05050994 | Karolinska Institutet | N/A |
| Unknown | TIPS Combined With Microwave Ablation in HCC Patients With Refractory Ascites NCT04640116 | Sun Yat-sen University | N/A |
| Recruiting | Relevance of Sarcopenia in Advanced Liver Disease NCT05502198 | Linkoeping University | — |
| Completed | Velacur by Sonic Incytes for Portal Hypertension NCT04576897 | Indiana University | N/A |
| Unknown | Extension Study of Carvedilol RCT Study NCT05021406 | Beijing Friendship Hospital | N/A |
| Completed | Accuracy of Magnetically Maneuvered Capsule Endoscopy for Detection of EGV in Patients With Cirrhosis NCT03748563 | Changhai Hospital | N/A |
| Unknown | EUS-guided PSE in Combination With EUS-guided Treatment of Varices for Patients With Portal Hypertension NCT04692805 | Tongji Hospital | N/A |
| Unknown | Endoscopic Ruler for the Assessment of Variceal Bleeding Risks (CHESS2005) NCT04639323 | Hepatopancreatobiliary Surgery Institute of Gansu Province | — |
| Unknown | Characterization and Pathogenesis of ACLF NCT04975490 | Johann Wolfgang Goethe University Hospital | — |
| Recruiting | EUS Guided Portal-systemic Pressure Gradient Measurement NCT04633356 | Chinese University of Hong Kong | Phase 1 / Phase 2 |
| Unknown | Gastroesophageal Varices in Cavernoma NCT04525768 | Shanghai Zhongshan Hospital | — |
| Completed | Efficacy and Safety of EUS-Guided Therapy Versus BRTO for Gastric Varices With Shunt NCT04828369 | Renmin Hospital of Wuhan University | — |
| Recruiting | Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease NCT04578301 | University Hospital, Bonn | — |
| Completed | Portal Pressure Effects of Phlebotomy Combined to Vasopressin Use in Cirrhotic Patients Undergoing Liver Trans NCT04472312 | Centre hospitalier de l'Université de Montréal (CHUM) | — |
| Recruiting | Non-invasive Evaluation Program for TIPS and Follow Up Network 2 (NEPTUN2) NCT04393519 | University Hospital, Bonn | — |
| Unknown | Multimodal Ultrasound and Portal Hypertension NCT05789641 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Recruiting | Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactulose NCT04073290 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Phase 4 |
| Unknown | Ivabradine in Cirrhotic Cardiomyopathy NCT04111133 | Post Graduate Institute of Medical Education and Research, Chandigarh | N/A |
| Completed | Timing of Endoscopy for Acute Variceal Bleeding in Patients With Cirrhosis NCT04957875 | Hepatopancreatobiliary Surgery Institute of Gansu Province | — |
| Unknown | Somatostatin in Living Donor Liver Transplantation NCT04107428 | King Faisal Specialist Hospital & Research Center | Phase 4 |
| Unknown | EGD vs EUS in Diagnosing Portal Hypertension in Cirrhotic Patients. NCT04191369 | Instituto Ecuatoriano de Enfermedades Digestivas | N/A |
| Completed | Perioperative Care of HVPG Measurement (CHESS1904): An International Multicenter Survey NCT04121520 | Hepatopancreatobiliary Surgery Institute of Gansu Province | — |
| Unknown | The Role of Somatostatin in the Hemodynamics of the Hepatic Circulation in Patients Undergoing Liver Resection NCT04010669 | Laikο General Hospital, Athens | Phase 3 |
| Unknown | The Influence of Post-transjugular Intrahepatic Portosystemic Shunt Hepatic Encephalopathy NCT03825848 | Shanghai Zhongshan Hospital | N/A |
| Recruiting | Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial. NCT05872698 | King's College Hospital NHS Trust | Phase 4 |
| Terminated | A Study Evaluating the Utility of Ambrisentan in Lowering Portal Pressure in Patients With Liver Cirrhosis NCT03827200 | Noorik Biopharmaceuticals AG | Phase 2 |
| Unknown | Non-invasive Method for Predicting the Presence of Gastroesophageal Varices in Patients With Cirrhosis NCT04123509 | Nanfang Hospital, Southern Medical University | — |
| Unknown | Propranolol, Carvedilol and Rosuvastatin in the Prevention of Variceal Bleeding in Cirrhotic Portal Hypertensi NCT03720067 | Universidade Federal do Rio de Janeiro | Phase 2 / Phase 3 |
| Unknown | HVPG-guided Laparoscopic Versus Endoscopic Therapy for Variceal Rebleeding in Portal Hypertension: A Multicent NCT03783065 | Nanfang Hospital, Southern Medical University | N/A |
| Completed | Myocardial Fibrosis and Inflammation in Liver Cirrhosis NCT05047029 | University Hospital, Bonn | — |
| Withdrawn | Splenic Embolization for Portal Hypertension NCT03532750 | University of Minnesota | N/A |
| Unknown | Treatment of Moderate and Severe Cirrhotic Portal Hypertension Due to HBV With Fuzheng Huayu and Entecavir NCT02945982 | ShuGuang Hospital | Phase 4 |
| Unknown | Treatment of Low-grade Cirrhotic Portal Hypertension Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir NCT02945956 | ShuGuang Hospital | Phase 4 |
| Recruiting | Austrian Registry on Transjugular Intrahepatic Portosystemic Shunts NCT03409263 | Thomas Reiberger | — |
| Completed | Assessment of Portal Hypertension With Multiparametric MRI NCT03436550 | Icahn School of Medicine at Mount Sinai | — |
| Completed | Anticoagulation Therapy After Splenectomy in Cirrhosis Patient NCT04397289 | First Affiliated Hospital Xi'an Jiaotong University | Phase 1 / Phase 2 |
| Completed | MRI to Assess the Effect of Terlipressin in Patients With Acute Hepatorenal Syndrome (HRS-AKI) NCT03483272 | Hvidovre University Hospital | — |
| Completed | Portal Hypertension Using Magnetic Resonance Elastography NCT05749198 | Yonsei University | — |
| Completed | Spironolactone on Fibrosis Progrssion-Portal Hypertension(FP-PH)in Cirrhosis NCT02907749 | Changqing Yang | Phase 4 |
| Completed | Feasibility And Safety Of Transjugular Intrahepatic Portosystemic Shunt (TIPS) Creation Using A Radiofrequency NCT03451149 | Oregon Health and Science University | N/A |
| Completed | Ultrasound Elastography Assessment of Spleen and Liver Stiffness Before and After Transjugular Intrahepatic Po NCT03427164 | University of Kansas Medical Center | N/A |
| Unknown | Noninvasive Diagnostic Platform for Liver Fibrosis and Portal Hypertension NCT03277651 | Shanghai Zhongshan Hospital | — |
| Unknown | Carvedilol for Prevention of Esophageal Varices Progression NCT03736265 | Beijing Friendship Hospital | N/A |
| Unknown | Low Molecular Weight Heparin for the Prevention of Early TIPS Dysfunction NCT03171727 | West China Hospital | N/A |
| Unknown | The Use of Propranolol for the Prevention of Worsening of Esophageal Varices in Patients With Isolated Gastric NCT03171805 | West China Hospital | N/A |
| Unknown | WFA+M2BP in Evaluation of Portal Hypertension and Clinical Outcome in Patients With Liver Cirrhosis NCT03195634 | Shanghai Changzheng Hospital | — |
| Unknown | 8mm-TIPS Versus Endoscopic Variceal Ligation (EVL) Plus Propranolol for Prevention of Variceal Rebleeding in P NCT03094234 | West China Hospital | N/A |
| Completed | MRI to Assess the Effect of Non-selective Beta-blocker in Patients With Cirrhosis NCT03438916 | Hvidovre University Hospital | — |
| Completed | Hemodynamic Alterations in Liver Cirrhosis Validated by Non-invasive MR Compared to Invasive Assessment NCT03443934 | Hvidovre University Hospital | — |
| Completed | Study to Assess Safety and Efficacy of Ifetroban for Treatment of Portal Hypertension in Cirrhotic Patients NCT02802228 | Cumberland Pharmaceuticals | Phase 2 |
| Completed | Utility of EUS-elastography to Predict Portal Hypertension NCT03155282 | Instituto Ecuatoriano de Enfermedades Digestivas | — |
| Completed | A Novel Approach for Transjugular Intrahepatic Portocaval Shunt Creation Using Real-time Three Dimensional Roa NCT03031366 | West China Hospital | N/A |
| Recruiting | VICIS - Vienna Cirrhosis Study NCT03267615 | Medical University of Vienna | — |
| Unknown | Can MRI Evaluate Beta-blocker Response in Portal Hypertension? NCT03114813 | University of Nottingham | — |
| Completed | FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE) NCT02922751 | Arbor Research Collaborative for Health | — |
| Terminated | A Study to Investigate the Safety and Effect of the Study Drug (FE 204205) in Patients With Cirrhotic Portal H NCT02929407 | Ferring Pharmaceuticals | Phase 1 |
| Completed | Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension NCT02960204 | Histogen | Phase 2 |
| Completed | Evaluation Of The Portal Pressure By Doppler Ultrasound In Cirrhotic Patients Before And After Simvastatin NCT02994485 | Tanta University | Phase 4 |
| Completed | Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14 NCT03439189 | Meridian Bioscience, Inc. | — |
| Terminated | Impact of Transjugular Intrahepatic Portosystemic Shunts on Liver Stiffness NCT03352882 | University of Pennsylvania | N/A |
| Completed | A Physical Activity Program in End-state Liver Disease NCT02776553 | University of Arkansas | N/A |
| Completed | Viatorr CX Case-control Study for Complications of Portal Hypertension NCT03083925 | University Hospital, Bonn | — |
| Unknown | Portal Hypertension and Systemic Endothelial Function NCT02850692 | Hopital Foch | N/A |
| Unknown | The International Imaging Registry in Liver Cirrhosis (BAVENO-VI SPSS GROUP). NCT02692430 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Completed | The Treatment of Hepatocirrhosis and Portal Hypertension NCT02778425 | Yanjing Gao | N/A |
| Completed | Effects of a Novel Physical Exercise Program in Patients With Cirrhosis (the LFN-exercise Protocol) NCT03932552 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | N/A |
| Completed | Comparative Analysis of Different Tests to Evaluate Prognosis of Patients on Liver Transplant Waiting List NCT01774617 | Guilherme Rezende | — |
| Unknown | TIPS in Fundal Variceal Bleeding (the TFB Study) NCT02364297 | Institut d'Investigacions Biomèdiques August Pi i Sunyer | N/A |
| Unknown | Effect of Administration of Rifaximin on the Portal Pressure of Patients With Liver Cirrhosis and Esophageal V NCT02508623 | University of Padova | Phase 3 |
| Completed | 8mm-TIPS Versus Endoscopic Variceal Ligation (EVL) Plus Propranolol for Prevention of Variceal Rebleeding NCT02477384 | West China Hospital | N/A |
| Unknown | 3D CT Guidance for Transjugular Intrahepatic Portosystemic Shunt Creation NCT02480426 | West China Hospital | N/A |
| Completed | Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension NCT02489045 | Thomas Jefferson University | Phase 4 |
| Withdrawn | A Pilot Study: Defining Peripheral Endothelial Function in Portal Hypertensive Cirrhotic Patients NCT02356250 | Eyal Ashkenazi | — |
| Unknown | Early Precise Diagnosis and Intervention of CPT Based on a Noninvasive 3D-vHPS NCT02925975 | Changqing Yang | Phase 4 |
| Unknown | Correlation of Platelets Count With Endoscopic Findings in a Cohort of Egyptian Patients With Liver Cirrhosis NCT02621372 | Sherief Abd-Elsalam | — |
| Completed | Transient Elastography to Assess Liver Fibrosis and Portal Hypertension in HCV Cirrhotic Patients Treated With NCT02439567 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Unknown | Doppler Ultrasound Hepatic Vein Waveform as a Non-invasive Tool in the Assessment of Severity of Portal Hypert NCT02975323 | Aga Khan University | Phase 3 |
| Completed | A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertension NCT02230683 | Conatus Pharmaceuticals Inc. | Phase 2 |
| Unknown | Laparoscopic Versus Open Devascularization for Portal Hypertension, a Randomized Controlled Trial NCT02178319 | Second Affiliated Hospital of Xi'an Jiaotong University | N/A |
| Completed | Surrogate Markers of Portal Pressure NCT02508298 | VA Connecticut Healthcare System | N/A |
| Completed | Evaluation of 3D Overlay During Transjugular Intrahepatic Portosystemic Shunt (TIPS) Procedure NCT02053571 | Medical College of Wisconsin | N/A |
| Completed | Microparticles in Cirrhosis and Portal Hypertension NCT02859610 | Centre Hospitalier Universitaire de Besancon | N/A |
| Completed | MBT Versus HVPG in Identifying Responders to Portal Hypertension Therapy NCT01851252 | Meridian Bioscience, Inc. | Phase 1 |
| Completed | Injection of Cyanoacrylate+Lipiodol vs Cyanoacrylate+Lauromacrogol in Gastric Varices NCT01923064 | Shanghai Zhongshan Hospital | N/A |
| Completed | 3D Sonographic Measurement of Volumetric Flow in Transjugular Intrahepatic Porto-Systemic Shunts NCT02046473 | University of Michigan | N/A |
| Unknown | Rifaximin and Propranolol Combination Therapy Versus Propranolol Monotherapy in Cirrhotic Patients NCT01897051 | Yonsei University | Phase 2 / Phase 3 |
| Completed | Role of SWE-change After TIPS in the Prediction of Prognosis After TIPS NCT03072615 | Jonel Trebicka | — |
| Terminated | Quality of Life and Nutritional Improvements in Cirrhotic Patients NCT01842113 | Tampa General Hospital | Phase 4 |
| Unknown | MRI in Portal Hypertension NCT01756859 | University of Nottingham | — |
| Completed | TIPS With 8- OR 10-mm Covered Stent for Preventing Variceal Rebleeding NCT01410591 | Air Force Military Medical University, China | N/A |
| Completed | Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without L NCT01687257 | Gilead Sciences | Phase 2 |
| Completed | Non-invasive Diagnosis of Portal Hypertension With Acoustic Radiation Force Impulse (ARFI) NCT01644656 | VA Connecticut Healthcare System | N/A |
| Completed | Probiotics for Liver Cirrhosis With Portal Hypertension NCT01598064 | Po-Lin Chen, MD | N/A |
| Completed | Risk Factors for Variceal Bleeding in Egyptian Patients With Non-Cirrhotic Portal Hypertension NCT02635815 | Ain Shams University | — |
| Completed | The Effectiveness of L-ornithine-L-aspartate (LOLA) on Plasma Ammonia in Cirrhotic Patients After TIPS NCT01440829 | Air Force Military Medical University, China | Phase 2 / Phase 3 |
| Completed | Esophageal Capsule Endoscopy in Children NCT01551966 | Hospices Civils de Lyon | N/A |
| Completed | Randomized Controlled Trial to Assess the Effects of Sapropterin on Hepatic and Systemic Hemodynamics in Patie NCT01456286 | Fundacion Clinic per a la Recerca Biomédica | Phase 2 / Phase 3 |
| Completed | HVPG for Rebleeding Risk Stratification NCT01751191 | Hospital Clinic of Barcelona | — |
| Unknown | Study About Simvastatin in Portal Hypertension in Compensated Cirrhosis NCT01282398 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 4 |
| Unknown | Hemodynamic Effect of Simvastatin With Beta Blockers in Clinical Portal Hypertension NCT01282385 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 4 |
| Terminated | Early TIPS for Ascites Study NCT01236339 | W.L.Gore & Associates | N/A |
| Completed | Effect of Taurine on Portal Hemodynamics in Patients With Advanced Liver Cirrhosis NCT02344719 | Medical University of Vienna | Phase 4 |
| Completed | Simvastatin Effect on Portal Hypertension NCT02134626 | Universidade Federal do Rio de Janeiro | Phase 3 |
| Unknown | ABMSC Infusion Through Hepatic Artery in Portal Hypertension Surgery for the Treatment of Liver Cirrhosis NCT01560845 | Wenzhou Medical University | Phase 2 / Phase 3 |
| Completed | Non Invasive Study of the Hepatic Fibrosis in Paediatrics by the Method of Study of Pediatric Hepatic Fibrosis NCT01072721 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | The Effect of Probiotics (VSL) on Portal Hypertension NCT01032941 | University of Alberta | Phase 1 / Phase 2 |
| Completed | Hepatectomy for Early-stage HCC Patients With CSPH NCT05402644 | Tongji Hospital | — |
| Completed | Effects of Dark vs. White Chocolate on the Postprandial Increase in Portal Pressure in Cirrhosis NCT01408966 | Hospital Clinic of Barcelona | Phase 2 |
| Terminated | Efficacy and Safety of Cobiprostone in Patients With Portal Hypertension NCT00737594 | Sucampo Pharma Americas, LLC | Phase 2 |
| Completed | Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope NCT01131962 | University of Alexandria | Phase 3 |
| Completed | Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community NCT00591968 | Edward Via Virginia College of Osteopathic Medicine | N/A |
| Unknown | Treatment for Prevention of Variceal Rebleeding Guided by the Hemodynamic Response NCT00563602 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 4 |
| Completed | Assessing Outcome After H-graft Shunt Placement NCT00519610 | University of South Florida | — |
| Completed | Evaluation of Probiotics in the Treatment of Portal Hypertension NCT00831337 | Pomeranian Medical University Szczecin | N/A |
| Unknown | Value of Von Willebrand Factor in Portal Hypertension NCT01358123 | Medical University of Vienna | — |
| Completed | Short Course Terlipressin for Control of Acute Variceal Bleeding NCT00369694 | Aga Khan University | Phase 4 |
| Unknown | Effect of Betablocker or Aldosterone Antagonist Therapy on Patients With Liver Cirrhosis NCT00332904 | Hvidovre University Hospital | Phase 4 |
| Completed | Use of Sanvar® With Endoscopic Treatment for the Control of Acute Variceal Bleeding NCT00331188 | Debiovision | Phase 3 |
| Withdrawn | Secondary Prophylaxis of Gastrointestinal Bleeding in Cirrhotic Patients Using THALIDOMIDE NCT00787436 | The Cleveland Clinic | Phase 3 |
| Terminated | Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal P NCT00414869 | Forest Laboratories | Phase 2 |
| Completed | A Trial of Somatostatin With Endoscopic Variceal Ligation (EVL) in Control of Acute Variceal Bleeding NCT01267669 | Govind Ballabh Pant Hospital | N/A |
| Completed | Endoscopic Resection of Early Esophageal Tumors in the Context of Cirrhosis or Portal Hypertension NCT04994548 | Central Hospital, Nancy, France | — |
| Completed | Effect of Pioglitazone on Portal and Systemic Hemodynamics in Patients With Advanced Cirrhosis NCT00570622 | Medical University of Vienna | Phase 4 |
| Completed | The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed NCT00534677 | Aga Khan University | Phase 4 |
| Completed | Portal Vein Stenting for Malignant Obstruction: Feasibility, Safety, and Clinical Outcomes NCT07252570 | Centre Hospitalier Universitaire de Nice | — |
| Completed | Efficacy and Safety of Simvastatin in the Treatment of Portal Hypertension NCT00594191 | Hospital Clinic of Barcelona | Phase 2 |
| Completed | Danish Carvedilol Study in Portal Hypertension NCT00493480 | Hvidovre University Hospital | Phase 3 |
| Completed | A Prospective Evaluation of Computerized Tomographic(CT) Scanning as a Screening Modality for Esophageal Varic NCT00587197 | Mayo Clinic | — |
| Completed | Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or Surgery NCT01931826 | Universidade Estadual de Ciências da Saúde de Alagoas | N/A |
| Completed | Endoscopic Variceal Ligation (EVL)+ Drugs Versus Endoscopic Variceal Ligation (EVL) Alone For Secondary Prophy NCT00766805 | Govind Ballabh Pant Hospital | N/A |
| Unknown | Transfusion Requirements in Gastrointestinal (GI) Bleeding NCT00414713 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 4 |
| Unknown | RCT of Carvedilol Versus Variceal Band Ligation in the Primary Prophylaxis of Oesophageal Variceal Haemorrhage NCT01070641 | Aga Khan University | Phase 4 |
| Completed | Secondary Prophylaxis After Variceal Bleeding in Non-Responders NCT00450164 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 4 |
| Completed | Non-invasive Evaluation Program for TIPS and Follow Up Network NCT03628807 | University Hospital, Bonn | — |
| Completed | Efficacy of Long-acting Octreotide (Sandostatin LAR) in Reducing Portal Pressure in Patients With Cirrhosis NCT01188733 | Mayo Clinic | Phase 1 / Phase 2 |
| Completed | Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis NCT00004796 | National Center for Research Resources (NCRR) | Phase 2 |
| Completed | Prevention of Esophageal Varices by Beta-Adrenergic Blockers NCT00006398 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 3 |
| Completed | Relationship of Vasoactive Peptide Levels to Portal Pressure and Patient Outcomes in Patients With Hepatic Cir NCT00163631 | Bayside Health | — |
| Unknown | Vasoactive Peptides in Portal Pressure NCT00163982 | Bayside Health | N/A |