Trials / Not Yet Recruiting
Not Yet RecruitingNCT07365709
Liver Cirrhosis Complicated by Clinically Significant Portal Hypertension
Liver Cirrhosis Complicated by Clinically Significant Portal Hypertension: the Role of Contrast-enhanced Ultrasound and Splenic Elastography for Non-invasive Assessment
- Status
- Not Yet Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 107 (estimated)
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Portal hypertension is a major complication of cirrhosis. HVPG is the diagnostic gold standard but is invasive. Non-invasive tools such as spleen stiffness measurement (SSM) and CEUS show promise for assessing CSPH, though they have not yet been compared directly. A multimodal ultrasound approach may provide a reliable alternative to HVPG.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | SonoVue | microbubbles infusion and ultrasound |
Timeline
- Start date
- 2026-02-01
- Primary completion
- 2026-07-31
- Completion
- 2026-12-31
- First posted
- 2026-01-26
- Last updated
- 2026-01-26
Source: ClinicalTrials.gov record NCT07365709. Inclusion in this directory is not an endorsement.