Clinical Trials Directory

Trials / Sponsors / Third Affiliated Hospital, Sun Yat-Sen University

Third Affiliated Hospital, Sun Yat-Sen University

Academic / Other · 126 registered clinical trials24 currently recruiting.

StatusTrialPhaseStarted
Active Not RecruitingPT-MSCs Exosome Injection in the Treatment of Chronic-to-acute Liver Failure
Acute-on-Chronic Liver Failure (ACLF)
EARLY_Phase 12026-01-01
Not Yet RecruitingTransarterial Chemoembolization With Low-Dose Bevacizumab Plus Atezolizumab as First-Line Treatment for Unrese
Hepatocellular Carcinoma, Transarterial Chemoembolization
N/A2026-01-01
Not Yet RecruitingEffectiveness of a Virtual Health Management Community (VHMC) for Pre-diabetes in China
Prediabetes
N/A2025-12-30
CompletedEstablishing a Virtual Health Community Management Model for Pre-Diabetes Patients
Prediabetes
N/A2025-12-22
Not Yet RecruitingTreatment of Spinal Cord Injury Using Autologous Concentrated Growth Factors
Spinal Cord Injury
EARLY_Phase 12025-12-01
Active Not RecruitingPhase I Trial of QH-1A Hybrid Bio-Artificial Liver With Ex Vivo Blood-Purifying MSCs in Acute-on-Chronic Liver
Acute-On-Chronic Liver Failure
Phase 12025-05-07
RecruitingProtein A immuNoaDsorption for the Treatment of Acute Episodes of Neuromyelitis Optica Spectrum Disorder
Neuromyelitis Optica Spectrum Disorders
N/A2025-04-25
Not Yet RecruitingMSC-EVs in Acute/ Acute-on-Chronic Liver Failure After Liver Transplantation
Liver Failure, Mesenchymal Stem Cell, Extracellular Vesicles
Phase 12025-04-01
CompletedEfficacy and Safety of an Intelligent Insulin-Dosing Decision Support System for Glycemic Control in Patients
Diabetes Mellitus,Type 2
N/A2025-03-01
RecruitingHospital-Based Management of Patients With Chronic Hepatitis B Virus Infection
Chronic Hepatitis B
2025-01-03
RecruitingEfficacy and Safety of Cytokine Adsorption and Plasma Exchange in Patients With ACLF and Sepsis
Acute-On-Chronic Liver Failure, Sepsis
N/A2024-09-27
Not Yet RecruitingLow-dose Gemcitabine and Cisplatin and PD-1/PD-L1 Antibody Therapy in Intrahepatic Cholangiocarcinoma
Intrahepatic Cholangiocarcinoma, Chemotherapy Effect, Immunotherapy
Phase 22024-09-01
Not Yet RecruitingA Randomized Clinical Trial of Intravenous Methylprednisolone With 2 Protocols in Patients With Graves Orbitop
Graves Ophthalmopathy
Phase 42024-07-01
Not Yet RecruitingThe Therapeutic Effect of Different Exercise Intensities on Weight Loss in Obese Children
Weight Loss, Obese Children and Adolescents
N/A2024-05-01
Not Yet RecruitingTwo-dimensional Shear Wave Elastography for Assessment of Cirrhosis and Portal Hypertension
Cirrhosis, Liver, Portal Hypertension
2024-04-01
RecruitingPRevention of OsTEoporotiC FracTure 2 Pilot Study
Fragility Fracture
N/A2024-01-13
CompletedStudy of the Correlation Between Donor CIRBP and Transplanted Kidney Function
Kidney Transplant; Complications, Delayed Graft Function
2023-12-01
RecruitingExploring the Efficacy and Safety of Ofatumumab in Patients With Relapsing Multiple Sclerosis (RMS) and Its Im
Multiple Sclerosis
2023-12-01
UnknownIndividual Nutrition Support in HBV-ACLF Patients at Nutrition Risk
Malnutrition, Hepatitis B,Chronic, Acute-On-Chronic Liver Failure
N/A2023-11-23
WithdrawnMSC-EV in Acute-on-Chronic Liver Failure After Liver Transplantation
Liver Failure, Acute on Chronic
Phase 12023-09-30
WithdrawnThe Safety and Efficacy of MSC-EVs in Acute/Acute-on-Chronic Liver Failure
Acute-On-Chronic Liver Failure, Acute Liver Failure
Phase 1 / Phase 22023-09-01
RecruitingTACE Plus Atezolizumab/Bevacizumab and I-125 Seeds Brachytherapy for HCC With Branch PVTT
Hepatocellular Carcinoma, Hepatic Portal Vein Tumor Invasion, Tumor Thrombus
N/A2023-08-30
UnknownEfficacy and Safety of Android Artificial Pancreas System in Adult Patients With Type 1 Diabetes Mellitus in C
Diabetes Mellitus, Diabetes Mellitus, Type 1, Glucose Metabolism Disorders
N/A2023-02-11
Completed2025 Hypoglycemia Early-Warning and Physician-Nurse Collaborative Management Trial in Type 2 Diabetes
Type 2 Diabetes Mellitus (T2DM)
N/A2023-02-01
UnknownLong-term Benefit of MPA in Liver Transplantation
Liver Transplant Rejection, Immunosuppressant Adverse Reaction
2022-12-04
UnknownCarrelizumab (PD-1) Combined With Chemotherapy in Neoadjuvant Treatment of Locally Advanced Gastric Cancer
Locally Advanced Gastric Cancer
Phase 22022-09-20
RecruitingEfficacy and Safety of ALSS Treatment for ICIs-LF in Patients With HCC
Immune-Mediated Hepatitis, Liver Failure, Hepatocellular Carcinoma
N/A2022-08-12
UnknownTACE/HAIC Combined With Lenvatinib and Sintilimab in Neoadjuvant Therapy for Intermediate-stage HCC
Hepatocellular Carcinoma
Phase 2 / Phase 32022-05-30
UnknownEnvafolimab as Neoadjuvant Immuntherapy in Resectable Local Advanced dMMR/MSI-H Colorectal Cancer
Colorectal Cancer, Mismatch Repair-deficient (dMMR), Microsatellite Instability-high (MSI-H)
Phase 22022-05-05
UnknownEfficacy and Safety of Avatrombopag for Treating TCP in HBV-ACLF Patients Receiving ALSS Treatment
Thrombocytopenia, Hepatitis B, Chronic, Acute-On-Chronic Liver Failure
Phase 42022-04-27
RecruitingPeginterferon Treatment Study for Inactive Chronic Hepatitis B Patients
Hepatitis B, Chronic
Phase 42022-01-08
CompletedClinical Application of Intrapartum Ultrasound
Abnormal Labor, Complication of Delivery
N/A2022-01-01
UnknownHBsAg Seroclearance in Adults With HBV Related Liver Fibrosis After Receiving Combined Therapy of Peg-IFN and
Liver Fibrosis
Phase 42021-01-01
RecruitingCombination of DPMAS and Low Volume PE for Patients With HBV Related ACLF
Hepatitis B, Chronic, Acute-On-Chronic Liver Failure
2020-12-22
UnknowniTBS Study for Depression in Patients With Multiple Sclerosis
Multiple Sclerosis, Depression, Anxiety
N/A2020-12-01
UnknownLDT Combined With TDF to Improve EGFR Decreasing in Patients With Chronic Hepatitis B Treated With TDF
Chronic Hepatitis B
2020-12-01
UnknownTDF Combined With LDT for the Treatment of HBeAg-positive Hepatitis B Patients With Poor Response to TDF for 1
Chronic Hepatitis B
2020-12-01
UnknownSafety and Efficacy of Camrelizumab (Anti-PD-1 Antibody) in Recurrent HCC After Liver Transplantation
Hepatocellular Carcinoma, Liver Transplantation
Phase 12020-09-21
UnknownThe Efficacy and Safety of TAF vs Other NAs in Patients With LVL
Chronic Hepatitis b, Cirrhosis Due to Hepatitis B
N/A2020-08-03
UnknownEfficacy and Safety of TAF in Pregnant Women With Chronic Hepatitis B Infection
Chronic Hepatitis B, Mother-to-child Block, Antiviral Treatment
EARLY_Phase 12020-08-01
RecruitingNucleoside (Acid) Analogues Treatment in Patients With Normal ALT and Positive HBVDNA.
Hepatitis B Virus
N/A2020-06-04
UnknownMIS-D Versus MIS-TLIF for the Treatment of Lumbar Spinal Stenosis
Spinal Stenosis
N/A2020-06-01
UnknownEarly Postoperative CRRT After Liver Transplantation in ACLF Patients With Overt HE
Acute-On-Chronic Liver Failure, Hepatic Encephalopathy
N/A2020-06-01
RecruitingLong-term Prognosis of Patients With Hepatitis B Related Acute-on-chronic Liver Failure
Hepatitis B, Acute-On-Chronic Liver Failure
2020-05-15
UnknownDetection of 2019 Novel Coronavirus in Multiple Organ System and Its Relationship With Clinical Manifestations
Coronavirus
2020-01-20
UnknownClinical Features of Suspected and Confirmed Patients of 2019 Novel Coronavirus Infection
Coronavirus
2020-01-20
RecruitingMultifaceted Comparison of Ultrasound-guided Ablation and Laparoscopic Adrenalectomy for Aldosterone-producing
Aldosterone-producing Adenoma, Radiofrequency Ablation
2020-01-01
UnknownRL-1 Novel Human-derived Bio-artificial Liver Treatment in Patients of HBV Related ACLF
Hepatitis B, Acute-On-Chronic Liver Failure
N/A2019-12-01
UnknownOptimized Treatment of Peginterferon Alfa 2a in Treatment Experienced Patients With HBV Related Liver Fibrosis
Hepatitis B, Liver Fibrosis
N/A2019-11-06
UnknownIntrathecal Transplantation of UC-MSC in Patients With Late Stage of Chronic Spinal Cord Injury
Spinal Cord Injuries
Phase 22019-09-01
UnknownComparison of the Efficacy and Safety of Immunoadsorption and Plasma Exchange for Acute Attack of Refractory N
Neuromyelitis Optica Spectrum Disorder
Phase 22019-09-01
UnknownThe Effect of Different Reconstruction Methods on Anterior Resection Syndrome
Rectal Cancer, Low Anterior Resection Syndrome
N/A2019-09-01
UnknownIntrathecal Transplantation of UC-MSC in Patients With Sub-Acute Spinal Cord Injury
Spinal Cord Injury
Phase 22019-09-01
UnknownIntrathecal Transplantation of UC-MSC in Patients With Early Stage of Chronic Spinal Cord Injury
Spinal Cord Injuries
Phase 22019-09-01
UnknownEvaluation of Early Retinal Nerve Injury in Type 2 Diabetes Patients Without Diabetic Retinopathy
Diabetes Mellitus, Diabetic Retinopathy, Nerve Injury
N/A2019-05-29
UnknownSystematic Imaging Examination in ODD
Optic Disk Drusen
2019-05-21
CompletedSystemic Inflammation in Liver Cirrhosis
Liver Cirrhosis
2019-04-01
UnknownReal-world Effectiveness and Safety of Treatment With DAAs in Patients With CHC(Chronic Hepatitis C)
Chronic Hepatitis C
2019-03-30
RecruitingThree Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF
Hepatitis B, Acute-On-Chronic Liver Failure
N/A2019-02-21
UnknownOptimized Treatment of Peginterferon Alfa 2a/2b in Treatment Experienced Patients With HBV Related Liver Fibro
Hepatitis B, Liver Fibrosis
N/A2019-02-01
UnknownOptimized Treatment of Peginterferon Alfa 2a/2b in Anti-virus Treatment Naive Patients With HBV Related Liver
Hepatitis B, Liver Fibrosis
N/A2019-02-01
UnknownTreatment Response Among Chinese Neuromyelitis Optica Spectrum Disorders
Neuromyelitis Optica Spectrum Disorders
2019-01-21
CompletedProphylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs
Surgical Site Infection, Postoperative Complications, Bowel Preparation
N/A2019-01-17
UnknownThree Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Hepatitis b Virus Related Compensated
Hepatitis B, Compensated Cirrhosis
N/A2019-01-01
UnknownThe Optimizing Treatment of Peginterferon Alpha in Chronic Hepatitis B Patients With Low Level HBsAg
Chronic Hepatitis B
Phase 42019-01-01
UnknownA Prospective Study to Monitor Liver Diseases Dynamically by Ultrasound Viscoelasticity
Cirrhosis, Liver Diseases
N/A2019-01-01
UnknownThree Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Chronic Hepatitis b
Chronic Hepatitis b
N/A2019-01-01
RecruitingOpen-Source Artificial Pancreas System Use Among People With Type 1 Diabetes Mellitus in China
Type 1 Diabetes Mellitus
2019-01-01
UnknownSOF/VEL±RBV: Efficacy and Safety in GT 3 and 6 HCV Patients
Hepatitis C
2018-12-08
CompletedEffect of Serum Vitamin D Level on the Efficacy of Peg-interferon Treatment in CHB
Chronic Hepatitis b
Phase 42018-12-01
UnknownOptimal Treatment for Poor Efficacy of Entecavir in Chronic Hepatitis B Patients
Chronic Hepatitis b, Efficacy, Self
N/A2018-11-15
UnknownAssessment of Liver Fibrosis and Prognosis in Chinese Patients With CHB Infection Using STE/STQ Elastography
Cirrhosis
2018-06-04
UnknownPlasma Exchange and Continuous Hemodiafiltration in Treatment of Wilson's Disease-related Liver Failure
Wilson Disease, Liver Failure
N/A2018-06-01
Active Not RecruitingThe Clinical Cure Project of Chronic Hepatitis B in China
Hepatitis B, Chronic
Phase 42018-05-16
UnknownPDCN for Treatment of Cervical Vertigo
Cervical Vertigo
N/A2018-01-01
CompletedOrigin of the Neonatal Gut Microbiota and Probiotic Intervention
Microbiota
N/A2018-01-01
UnknownUS-MR Image Fusion-guided Percutaneous Transforaminal Endoscopic Discectomy for the Treatment of Lumbar Disc H
Lumbar Herniated Disc
N/A2018-01-01
UnknownThe Activation of Hippo Pathway in Nasal Polyps
Nasal Polyps
N/A2017-04-20
CompletedExplainable Machine Learning for the Assessment of Donor Grafts in Liver Transplantation
Liver Transplant; Complications
2017-01-01
UnknownHBsAg Loss/Seroconversion in Low Replicative Chronic Hepatitis B Virus(HBV) Infection Patients
Chronic Hepatitis B
Phase 42016-08-01
UnknownThe Optimizing Treatment of Peginterferon (PEG IFN) Alpha in Chronic Hepatitis B Virus Patients With Low Level
Chronic Hepatitis B
Phase 42016-08-01
UnknownThe Optimizing Treatment of PegIFN Alfa in HBeAg-negative CHB Patients With Low Level HBsAg
Chronic Hepatitis B
Phase 42016-06-01
Not Yet RecruitingOral Vitamin D Treatment for the Prevention of Hepatocellular Carcinoma
Hepatitis B, Carcinoma, Hepatocellular
Phase 42016-06-01
CompletedThe Effects of Metformin on Glycemic Control and Insulin Sensitivity in Adolescents With T1DM
Diabetes Mellitus, Type 1
Phase 42016-06-01
UnknownFollow-up Strategy of Chronic Hepatitis B for Early Detection and Diagnosis of Hepatocellular Carcinoma: A Ran
Chronic Hepatitis B
2016-05-01
UnknownThe Optimizing Treatment of PegIFN Alfa in HBeAg-negative CHB Patients With Low Level HBsAg
Chronic Hepatitis B
Phase 42016-04-01
UnknownICG-based Fluorescence Imaging in Localization of Prostate Cancer and Metastatic Lymph Nodes
Prostate Cancer
Phase 12016-03-01
UnknownNew Strategy Study of Functional Cure of Chronic Hepatitis B
Hepatitis B, Chronic
N/A2016-03-01
CompletedThe Relationship Between MDSCs and NK Cells Activity of CHC Patient Treated by DAAs
Chronic Hepatitis C
EARLY_Phase 12016-02-01
CompletedDynamic Changes of Monocytes and NK Cells of CHC Patient Treated by DAAs
Chronic Hepatitis C (Disorder)
2016-01-01
UnknownPeginterferon Alfa-2b Treatment in HBeAg(+) Chronic Hepatitis b Patients Based on Interferon Gene Mutation and
Chronic Hepatitis b
Phase 42016-01-01
UnknownMycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients
Neuromyelitis Optica Spectrum Disorders, Mycophenolate Mofetil, Efficacy and Safety
Phase 42016-01-01
UnknownA Clinical Trial on Hepatitis B Vaccine Activated-Dendritic Cells Combined With Anti-HBV Drugs in CHB
Chronic Hepatitis B
Phase 1 / Phase 22015-11-01
UnknownComparison of Diabetes Retinopathy Among Type 2 Diabetic Patients Treated With Different Regimens
Diabetic Retinopathy
EARLY_Phase 12015-07-01
CompletedA Comparative Study of Two Endoscopic Operations for Lacrimal Duct Obstruction
Lacrimal Duct Obstruction
Phase 1 / Phase 22015-07-01
UnknownComparison of Glycaemic Fluctuation and Oxidative Stress Between Two Short-term Therapies for Type 2 Diabetes
Diabetes Mellitus, Type 2
Phase 42015-07-01
CompletedThe Safety of Anti-viral Therapy in Preventing HBV MTCT in Pregnant Women After Discontinuation
Hepatitis B, Chronic
Phase 42015-06-01
UnknownFolic Acid for Prevention of Contrast Induced Nephropathy
Kidney Diseases, Urologic Diseases
Phase 42015-05-01
UnknownEntecavir Combined Short-term Intravenous Hepatitis B Immune Globulin (HBIG) to Prevent Hepatitis B Recurrence
Hepatitis B, Liver Transplantation
Phase 42015-04-01
CompletedMulticenter Study on Preservation Versus Excision of Denonvilliers Fascia in L-PANP Surgery
Rectal Cancer
N/A2015-04-01
UnknownPreservation Versus Excision of Denonvilliers Fascia in L-PANP Surgery
Rectal Cancer
N/A2015-02-01
CompletedLaparoscopic Colorectal Resection in Elderly
Colorectal Cancer
2015-01-20
CompletedLARS for Chinese Patients
Incidence and Risk Factors of Low Anterior Resection Syndrome
2015-01-01
CompletedA Clinical Trial on HB-Vac Activated-DCs Combined With Peg-IFN or NAs in CHB
Chronic Hepatitis B
Phase 1 / Phase 22015-01-01
UnknownSafety Study of NK Cells From Sibship to Treat the Recurrence of HCC After Liver Transplantation
Hepatocellular Carcinoma
Phase 12014-10-01
UnknownSingle-center Study on Laparoscopic Distal Subtotal Gastrectomy for Advanced Gastric Cancer
Stomach Neoplasms
N/A2014-07-01
UnknownLaparoscopic Versus Open PANP-TME for Male Mid-low Rectal Cancer Patients
Rectum Neoplasms
N/A2014-06-01
UnknownAccuracy of RTE for Evaluating Hepatic Fibrosis in Chronic Hepatitis: a Prospective Multicenter Study
Chronic Hepatitis
2014-05-01
UnknownTherapeutic Strategy and the Role of Mesenchymal Stromal Cells for ABO Incompatible Liver Transplantation
Liver Transplantation
Phase 1 / Phase 22014-02-01
RecruitingTherapeutic Effects and Long-term Follow-up After Ending Nucleos(t)Ide Analogs Therapy in Chronic Hepatitis b
Chronic Hepatitis b
2014-01-01
UnknownMulticenter Study on Laparoscopic Versus Open PANP-TME for Male Mid-low Rectal Cancer Patients
Rectum Neoplasms
N/A2014-01-01
UnknownA RCT of Compound Lidocaine Cream to Prevent Postoperative Agitation in Patients With Endotracheal Intubation
Postoperative Agitation of Patients
Phase 42013-12-01
UnknownPercutaneous Transforaminal Endoscopic Discectomy vs Microendoscopic Discectomy for Treatment of Lumbar Disc H
Lumbar Herniated Disc
Phase 42013-10-01
UnknownPrognosis Scoring System for Acute-on-Chronic Liver Failure
Liver Failure
2013-10-01
UnknownSafety and Efficacy of Diverse Mesenchymal Stem Cells Transplantation for Liver Failure
Liver Failure
Phase 1 / Phase 22013-07-01
UnknownEfficacy of Short-term Immunosuppressive Therapy and Anti-allergenic Therapy in Severe Acute Exacerbation of C
Severe Acute Exacerbation of Chronic Hepatitis B
N/A2012-12-01
UnknownPreliminary Study of Sonic Hedgehog Signaling Pathway in the Pathogenesis of Rheumatoid Arthritis
Arthritis, Rheumatoid, Neovascularization, Pathologic, Synovitis
2012-11-01
UnknownUmbilical Cord Mesenchymal Stem Cells Transplantation Combined With Plasma Exchange for Patients With Liver Fa
Liver Failure
Phase 1 / Phase 22012-11-01
CompletedResponse to Pegylated Interferon and Ribavirin in Chinese Patients With Chronic Hepatitis C Genotypes 1 Versus
Chronic Hepatitis C
Phase 32011-11-01
UnknownA Randomized Trial of 24-Week Versus 48-Week Courses of Peginterferon Plus Ribavirin for Patients With Genotyp
Chronic Hepatitis C
Phase 32011-05-01
CompletedA Two-year Study of Telbivudine in HBeAg Negative Hepatitis
Hepatitis B, Chronic
Phase 42011-01-01
CompletedProphylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs: A Propensity Analysis
Surgical Site Infection, Colorectal Cancer
2011-01-01
UnknownRadiomics for Diagnosing Liver Diseases and Evaluating Progression
Hepatitis B / Liver Space-occupying Lesions / Patients After Ablation
2011-01-01
CompletedA Randomized Trial of 24-Week Versus 48-Week Courses of Peginterferon Plus Ribavirin for HCV Genotype-6 Patien
Chronic Hepatitis C
Phase 32010-12-01
CompletedEfficacy and Safety of Peginterferon a-2a in Patients of Chronic Hepatitis B With Spontaneous Decline of HBV D
Antiviral Treatment of Chronic Hepatitis B
Phase 32010-01-01
UnknownEpidemiological Analysis on Endometrial Cancer in Guangdong Province of China
Endometrial Cancer
2000-01-01