Trials / Unknown
UnknownNCT06128421
Individual Nutrition Support in HBV-ACLF Patients at Nutrition Risk
Individual Nutrition Support in HBV-ACLF Patients at Nutrition Risk: a Randomized Controlled Trail
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University · Academic / Other
- Sex
- All
- Age
- 20 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to investigate the safety and efficacy of individual nutrition support for treating hepatitis b virus(HBV) related acute-on-chronic liver failure patients at nutrition risk
Detailed description
The aims of the randomized-controlled trial are to test the hypothesis that in medical inpatients with HBV related ACLF at risk for undernutrition defined by the nutritional risk score (NRS 2002), tailored nutritional therapy to reach nutritional targets based on individualized nutritional counseling is a effective strategy to prevent mortality, morbidity and functional decline. Sixty patients with HBV related ACLF will be enrolled in this study. The participants are divided into trial Patients in the trail group will receive individualized nutritional therapy to reach nutritional targets (caloric, protein, others) based on a predefined nutritional strategy.In control patients, according to patients' appetite, standard hospital nutrition will be served. Nutritional therapy may be started in control patients, if any sort of swallowing disorders develops or if patients need to be prepared for operation. All patients will be re-assessed daily during the hospital stay for nutritional intake and nutritional therapy may be escalated within first 3days ( oral supplements, parenteral nutrition) if targets are not met (at least 75% of targets).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Individual nutritional support | Nutritional products and route（oral, parenteral）is possible to reach goals |
Timeline
- Start date
- 2023-11-23
- Primary completion
- 2024-04-30
- Completion
- 2024-10-31
- First posted
- 2023-11-13
- Last updated
- 2024-01-25
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06128421. Inclusion in this directory is not an endorsement.