NCT07502729

Optimizing Endoscopic and Interventional Treatment for Portal Hypertensive Bleeding

Improve the Strategies of Endoscopic and Interventional Treatment of Gastroesophageal Hemorrhage in Portal Hypertension

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,066 (estimated)
• Sponsor: Shanghai Zhongshan Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the impact of high-risk factors-such as elevated portal venous pressure, concurrent large extra-luminal vessels, portal vein thrombosis, and prominent portosystemic shunts-on the efficacy of endoscopic therapy. By comparing with interventional treatment, the goal is to optimize the clinical management protocol for esophageal and gastric varices, enhance the therapeutic outcomes of portal hypertension-related esophageal and gastric varices, and improve patient prognosis.

Conditions

• Portal Hypertension
• Gastroesophageal Varices Hemorrhage
• Gastric Varices
• Esophageal Varices

Timeline

• Start date: 2026-03-17
• Primary completion: 2026-12-31
• Completion: 2027-12-31
• First posted: 2026-03-31
• Last updated: 2026-03-31