NCT04639323

Endoscopic Ruler for the Assessment of Variceal Bleeding Risks (CHESS2005)

Endoscopic Ruler for the Assessment of Variceal Bleeding Risks in Portal Hypertension (CHESS2005): A Prospective Multicenter Trial

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 266 (estimated)
• Sponsor: Hepatopancreatobiliary Surgery Institute of Gansu Province · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The presence of varices is a serious complication of portal hypertension in liver disease. To prevent variceal haemorrhage, screening and surveillance aims to detect high-risk varices related to varices size and determine the need for primary prophylaxis. Varices size evaluated by endoscopists might not be perfect reference, influenced by experience and machine. Endoscopic ruler is a novel tool to measure the varices size under the endoscopy. The investigators aim to evaluate the bias of varices size between endoscopists and endoscopic ruler as the reference.

Conditions

• Liver Cirrhosis
• Portal Hypertension
• Gastroesophageal Varices

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Endoscopic ruler	Endoscopic ruler for varices in portal hypertension Product uses: measuring the diameter of the veins under the endoscopy for the assessment of the risk of variceal haemorrhage in patients with portal hypertension Black and white measuring rule is highly recognizable under the endoscopy The width of each cell is 1 mm, and the measuring range is 0-10 mm With smooth edge, safe and reliable

Timeline

• Start date: 2020-12-23
• Primary completion: 2023-04-01
• Completion: 2025-01-01
• First posted: 2020-11-20
• Last updated: 2023-04-25

Locations

7 sites across 1 country: China