| Recruiting | Prospective Clinical Evaluation of the BioFire Emerging Coronavirus Panel for the Detection of COVID-19 and Ot NCT07221097 | BioFire Defense LLC | — |
| Recruiting | The Effects of Endotracheal Suctioning on Pain and Serum Markers NCT06692400 | Loma Linda University | N/A |
| Completed | Covid-19 Data Analyses in Brazil NCT06652451 | AstraZeneca | — |
| Recruiting | Clinical Validation of the Aptitude Medical Systems Metrix COVID-19 Test NCT06744660 | Aptitude Medical Systems | N/A |
| Completed | Evaluation of Immunogenicity of COVID-19 Vaccine in Chinese Population NCT06763887 | Xijing Hospital | — |
| Withdrawn | Efficacy of Pentoxifylline as Add on Therapy in COVID19 Patients NCT04433988 | Sadat City University | Phase 1 / Phase 2 |
| Suspended | Preventing Pulmonary Complications in Surgical Patients at Risk of COVID-19 NCT04386070 | University of Birmingham | Phase 3 |
| Withdrawn | Niclosamide In Moderate COVID-19 NCT04436458 | Entero Therapeutics | Phase 2 |
| Withdrawn | Inhaled ZYESAMI (Aviptadil Acetate) for Treatment of Severe COVID-19 NCT05137795 | APR Applied Pharma Research s.a. | Phase 3 |
| Unknown | Impact of Confinement and Preventive Measures in Period of SARS-COV2 Infection on Clinical Features, Diagnosti NCT04366219 | Centre Hospitalier le Mans | — |
| Completed | Risk of Air Contamination During Visceral Surgery in COVID19 Patients NCT04395599 | University Hospital, Lille | N/A |
| Withdrawn | COVIDNOCHE Trial (HFNO Versus CPAP Helmet) in COVID-19 Pneumonia NCT04381923 | University of Pennsylvania | N/A |
| Withdrawn | Characteristics of Patients With COVID-19 in Meta State, Colombia NCT04456426 | Hospital Departamental de Villavicencio | — |
| Completed | Detecting SARS-CoV-2 in Tears NCT04526769 | University of Minnesota | — |
| Recruiting | Outpatient Treatment With Anti-Coronavirus Immunoglobulin NCT04910269 | University of Minnesota | Phase 3 |
| Unknown | Combination of Recombinant Bacterial ACE2 Receptors -Like Enzyme of B38-CAP and Isotretinoin Could be Promisin NCT04382950 | Kafrelsheikh University | Phase 1 |
| Withdrawn | Emergency Department (ED) Self-Monitoring Pilot COVID-19 NCT04462783 | University of Michigan | N/A |
| Withdrawn | Maintenance Versus Reduction of Immunosuppression for Renal Transplant Patients Hospitalized With COVID-19 Dis NCT04420364 | Brigham and Women's Hospital | Phase 2 / Phase 3 |
| Completed | Primary Prevention of Infection by COVID-19 in Workers NCT04420260 | Unidad de Investigación Genética Molecular | N/A |
| Terminated | Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19 NCT04360096 | APR Applied Pharma Research s.a. | Phase 2 / Phase 3 |
| Unknown | Evaluation of the Psychosocial Impact on Health Professionals Exposed During COVID 19 Coronavirus Pandemic NCT04752839 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | — |
| Unknown | Immunity and Infections in the Psychiatric Population NCT04381845 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ve NCT04467086 | Ottawa Hospital Research Institute | Phase 3 |
| Unknown | RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study NCT04659460 | Unity Health Toronto | N/A |
| Completed | Trial of Combination Therapy to Treat COVID-19 Infection NCT04482686 | ProgenaBiome | Phase 1 |
| Terminated | Compensatory Reserve Index (CRI) for Management of COVID-19 NCT04457817 | University of Colorado, Denver | — |
| Unknown | Efficacy of Subcutaneous Ivermectin With or Without Zinc in COVID-19 Patients NCT04472585 | Sohaib Ashraf | Phase 1 / Phase 2 |
| Unknown | Telepsychoeducation for the Prevention of Emotional Distress in Professionals and Students From Essential Serv NCT04632082 | Hospital de Clinicas de Porto Alegre | N/A |
| Unknown | Psychotherapy Strategies for the Treatment of Professionals and Students From Essential Services With High Lev NCT04635618 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Evaluation of a ddPCR Technology for the SARS-CoV-2 Detection in Symptomatic Patients With Suspicion of COVID- NCT04510454 | Centre Leon Berard | N/A |
| Completed | Caregiver Serological Monitoring Extended Secondarily to Patients With the SARS-CoV-2 Coronavirus NCT04441710 | Hospices Civils de Lyon | — |
| Completed | WAVE. Wearable-based COVID-19 Markers for Prediction of Clinical Trajectories NCT04357834 | Insel Gruppe AG, University Hospital Bern | — |
| Terminated | Open-label Multicenter Study to Evaluate the Efficacy of PLX-PAD for the Treatment of COVID-19 NCT04614025 | Pluristem Ltd. | Phase 2 |
| Completed | LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID- NCT04402957 | Arch Biopartners Inc. | Phase 2 |
| Unknown | Remote Monitoring of Cancer Patients With Suspected Covid-19 NCT04397705 | The Christie NHS Foundation Trust | Phase 1 |
| Completed | RAS and Coagulopathy in COVID19 NCT04419610 | Imperial College London | EARLY_Phase 1 |
| Completed | Inpatient Treatment of COVID-19 With Anti-Coronavirus Immunoglobulin (ITAC) NCT04546581 | University of Minnesota | Phase 3 |
| Terminated | Coronavirus Induced Acute Kidney Injury: Prevention Using Urine Alkalinization NCT04530448 | West Virginia University | Phase 4 |
| Completed | Lung Damage Caused by SARS-CoV-2 Pneumonia (COVID-19) NCT04435327 | University of Milano Bicocca | — |
| Unknown | COVID-19 : Transcutaneous pO2 and pCO2 as Predictive Factors for Acute Respiratory Destress Syndrome in Patien NCT04524156 | Erasme University Hospital | N/A |
| Completed | Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS) NCT04530604 | Gregory Yanik | Phase 1 |
| Unknown | Low Dose Pulmonary Irradiation in Patients With COVID-19 Infection of Bad Prognosis NCT04414293 | Hospital Provincial de Castellon | N/A |
| Completed | Maraviroc in Patients With Moderate and Severe COVID-19 NCT04435522 | Rhode Island Hospital | Phase 1 |
| Terminated | Double-Blind, Multicenter, Study to Evaluate the Efficacy of PLX PAD for the Treatment of COVID-19 NCT04389450 | Pluristem Ltd. | Phase 2 |
| Unknown | New Antiviral Drugs for Treatment of COVID-19 NCT04392427 | Mansoura University | Phase 3 |
| Completed | Early EMDR Following Covid-19 Critical Illness: A Feasibility Trial NCT04455360 | University Hospital Southampton NHS Foundation Trust | N/A |
| Unknown | Prognostication of Oxygen Requirement in Non-severe SARS-CoV-2 Infection NCT04441372 | Medecins Sans Frontieres, Spain | — |
| Unknown | P2Et Extract in the Symptomatic Treatment of Subjects With COVID-19 NCT04410510 | Hospital Universitario San Ignacio | Phase 2 / Phase 3 |
| Completed | Synbiotic Therapy of Gastrointestinal Symptoms During Covid-19 Infection NCT04420676 | Medical University of Graz | N/A |
| Completed | Efficacy of N-Acetylcysteine (NAC) in Preventing COVID-19 From Progressing to Severe Disease NCT04419025 | Cambridge Health Alliance | Phase 2 |
| Completed | Safety and Efficacy of SCD in AKI or ARDS Patients Associated With COVID-19 Infections NCT04395911 | SeaStar Medical | N/A |
| Completed | Detection of SARS-CoV-2 in Follicular Fluid and Cumulus-oocyte-complexes in COVID-19 Patients NCT04425317 | CRG UZ Brussel | N/A |
| Terminated | Low-Dose Tenecteplase in Covid-19 Diagnosed With Pulmonary Embolism NCT04558125 | Cedars-Sinai Medical Center | Phase 4 |
| Suspended | Cytokine Adsorption in Patients With Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation NCT04385771 | Dr. Alexander Supady | N/A |
| Completed | Use of Remote Monitoring for COVID-19 Patient NCT04425720 | Montefiore Medical Center | N/A |
| Completed | Investigation of the Efficacy of CARDIO Softgels PLUS Best-standard-of-care in the Recovery of Patients With C NCT04465513 | Hofseth Biocare ASA | N/A |
| Unknown | AKI Biomarkers in Coronavirus(COVID)-19 NCT04408248 | Guy's and St Thomas' NHS Foundation Trust | — |
| Completed | In-Utero Vascular Accidents in Neonates From COVID-19 Infected Mothers NCT04431869 | University of Colorado, Denver | — |
| Withdrawn | Whole Blood Collection From Individuals in the Convalescent Phase of SARS-CoV-2 Infection NCT04409184 | Medical College of Wisconsin | — |
| Completed | Coagulation Changes Associated With COVID-19 Infection NCT04460664 | HemoSonics LLC | — |
| Completed | Cholecalciferol to Improve the Outcomes of COVID-19 Patients NCT04411446 | Vitamin D Study Group | Phase 4 |
| Completed | Intensive Care Therapy of Covid-19 Disease in Germany NCT04455451 | University Hospital Tuebingen | — |
| Unknown | Endothelial Function, Inflammation and Organ Dysfunction in COVID-19 NCT04408365 | Guy's and St Thomas' NHS Foundation Trust | — |
| Completed | Safety and Efficacy of NP-120 (Ifenprodil) for the Treatment of Hospitalized Patient With Confirmed COVID-19 D NCT04382924 | Algernon Pharmaceuticals | Phase 2 / Phase 3 |
| Unknown | The Açaí Berry COVID-19 Anti-Inflammation Trial NCT04404218 | University Health Network, Toronto | Phase 2 |
| Terminated | Study of the Safety of Therapeutic Tx With Immunomodulatory MSC in Adults With COVID-19 Infection Requiring Me NCT04397796 | ImmunityBio, Inc. | Phase 1 |
| Withdrawn | COVID 19: Is SARS-CoV-2 Contaminating Surgical Aerosols From Laparoscopy and Open Abdominal Surgery? NCT04444687 | University Hospital, Basel, Switzerland | — |
| Unknown | Sofosbuvir in Treatment of COVID 19 NCT04460443 | Tanta University | Phase 2 / Phase 3 |
| Unknown | Knowledge, Attitudes, and Practices Towards COVID-19 Among Health Care Professionals Among Healthcare Professi NCT04492202 | Istinye University | — |
| Unknown | An Adaptive Clinical Trial of Antivirals for COVID-19 Infection NCT04445467 | Bayside Health | Phase 2 |
| Completed | The Use of Ultrasound in Establishing COVID-19 Infection as Part of a Trauma Evaluation NCT04340479 | University of Colorado, Denver | — |
| Completed | Non Inferiority Trial for Detection of nCOVID-19 Through Analysis of Exhaled Breath Aerosols NCT04467112 | Owlstone Ltd | — |
| Completed | Functional and Respiratory Rehabilitation and Nutritional Care of COVID-19 Patients (RECOVER-19) NCT04466800 | Rennes University Hospital | N/A |
| Completed | Study of Mavrilimumab (KPL-301) in Participants Hospitalized With Severe Corona Virus Disease 2019 (COVID-19) NCT04447469 | Kiniksa Pharmaceuticals International, plc | Phase 2 / Phase 3 |
| Terminated | Early Treatment With Ivermectin and LosarTAN for Cancer Patients With COVID-19 Infection NCT04447235 | Instituto do Cancer do Estado de São Paulo | Phase 2 |
| Unknown | Convalescent Plasma for COVID-19 NCT04365439 | Enos Bernasconi | N/A |
| Completed | OPV as Potential Protection Against COVID-19 NCT04445428 | Bandim Health Project | Phase 4 |
| Completed | Sofosbuvir/Ledipasvir and Nitazoxanide for Treatment of COVID-19 NCT04498936 | Assiut University | Phase 4 |
| Unknown | Influence of COVID-19 on Vascular Endothelial Function NCT04468412 | Radboud University Medical Center | — |
| Terminated | Use of Convalescent Plasma for COVID-19 NCT04408040 | Northside Hospital, Inc. | Phase 2 |
| Unknown | "NORPLASMA" Covid-19 Convalescent Plasma Treatment Monitoring Study NCT04463823 | Oslo University Hospital | — |
| Completed | COVID-19 Infection and Machine Learning Using Artificial Intelligence (AI) NCT04756518 | East Suffolk and North Essex NHS Foundation Trust | — |
| Unknown | Pulmozyme to Improve COVID-19 ARDS Outcomes NCT04402944 | Boston Children's Hospital | Phase 2 |
| Completed | A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Respons NCT04444700 | University of Sao Paulo General Hospital | Phase 3 |
| Completed | Convalescent Plasma in Pediatric COVID-19 NCT04458363 | Emory University | EARLY_Phase 1 |
| Completed | Evaluation of the Containment Impact Linked to the Covid-19 Pandemic in a Population of Parkinson Patients NCT04466839 | University Hospital, Toulouse | — |
| Terminated | CICERO- A Care Home Study of COVID-19 NCT04453553 | Queen Mary University of London | N/A |
| Unknown | Administration of Allogenic UC-MSCs as Adjuvant Therapy for Critically-Ill COVID-19 Patients NCT04457609 | Indonesia University | Phase 1 |
| Completed | BCG Vaccine in Reducing Morbidity and Mortality in Elderly Individuals in COVID-19 Hotspots NCT04475302 | Tuberculosis Research Centre, India | Phase 3 |
| Unknown | Indirect Endovenous Systemic Ozone for New Coronavirus Disease (COVID19) in Non-intubated Patients NCT04359303 | Javier Hidalgo Tallón | Phase 3 |
| Withdrawn | A Study of Combination Therapies to Treat COVID-19 Infection NCT04459702 | ProgenaBiome | Phase 2 |
| Unknown | Therapeutic Vaccine Trial of COVID-19 for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infecti NCT04428073 | GeneCure Biotechnologies | Phase 1 |
| Completed | Ruxolitinib for Treatment of Covid-19 Induced Lung Injury ARDS NCT04359290 | Philipps University Marburg | Phase 2 |
| Completed | Surgical Telemedicine in the COVID-19 Pandemic Era NCT04376710 | University of Colorado, Denver | — |
| Completed | Monovalent Recombinant COVID19 Vaccine NCT04453852 | Vaxine Pty Ltd | Phase 1 |
| Completed | PROne Positioning in coVID-19 Oxygeno-dependent Patients in Spontaneous Ventilation (PROVID Study) NCT04366856 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19 NCT04447534 | Tanta University | Phase 3 |
| Terminated | Hypertonic Saline Nasal Irrigation and Gargling in Suspected or Confirmed COVID-19 (ELVIS COVID-19) NCT04382131 | University of Edinburgh | N/A |
| Completed | A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection NCT04335084 | ProgenaBiome | Phase 2 |
| Terminated | Pegylated Interferon Lambda Treatment for COVID-19 NCT04343976 | Raymond Chung | Phase 2 |
| Unknown | Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19 and High Risk of Acute Kidney Inj NCT04445259 | Guy's and St Thomas' NHS Foundation Trust | — |
| Completed | Telerehabilitation After Coronavirus NCT04473898 | KTO Karatay University | N/A |
| Terminated | hCT-MSCs for COVID19 ARDS NCT04399889 | Joanne Kurtzberg, MD | Phase 1 / Phase 2 |
| Completed | International SARS-CoV-2 (COVID-19) Infection Observational Study NCT04385251 | University of Minnesota | — |
| Active Not Recruiting | Mesenchymal Stromal Cell Therapy For The Treatment Of Acute Respiratory Distress Syndrome NCT04447833 | Uppsala University | Phase 1 |
| Unknown | One-year Outcomes in Survivors of the Severe COVID-19 Pneumonia (CO-Qo-ICU) NCT04401111 | Centre Hospitalier Universitaire de Nice | — |
| Recruiting | The Efficacy of Ivermectin in Larger Doses in COVID-19 Treatment NCT04351347 | Tanta University | Phase 2 / Phase 3 |
| Completed | Remdesivir Efficacy in Coronavirus Disease NCT04345419 | Tanta University | Phase 2 / Phase 3 |
| Unknown | Hydroxy Chloroquine and Covid in RA Patients NCT04471649 | Tanta University | — |
| Completed | Short Term, High Dose Vitamin D Supplementation for COVID-19 NCT04459247 | Post Graduate Institute of Medical Education and Research, Chandigarh | N/A |
| Completed | Evaluation of Vaginal Fluid for Covid-19 Positivity in Women With Positive Nasofarengeal Covid-19 Test NCT04437940 | Acibadem University | — |
| Completed | Impact of the Covid-19 Pandemic on Gastrointestinal and Liver Diseases NCT04420637 | Medical University of Graz | — |
| Unknown | COVID19 Clinical Predictors and Outcome NCT04416347 | St George's University Hospitals NHS Foundation Trust | — |
| Completed | Efficacy of Convalescent Plasma Therapy in Patients With COVID-19 NCT04425915 | Institute of Liver and Biliary Sciences, India | Phase 3 |
| Unknown | Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment NCT04378881 | Tabula Rasa HealthCare | — |
| Withdrawn | Assessment of Mortality Rates in COVID-19 Infected Populations Treated With Repurposed Medications NCT04432350 | Tabula Rasa HealthCare | — |
| Unknown | Prevalence and Risk Factors of SARS-CoV-2 Antibody Responses (COVID-19) NCT04425759 | Hospital de Mataró | — |
| Completed | Sero-prevalence of Coronavirus Disease 2019 (COVID-19) in Healthcare Workers NCT04424017 | Egyptian Center for Research and Regenerative Medicine | — |
| Completed | Prevention of Severe Covid-19 in Infected Elderly by Early Administration of Convalescent Plasma With High-tit NCT04479163 | Fundacion Infant | N/A |
| Completed | SafeFit Trial: Virtual Clinics to Deliver Universal Interventions in People With Cancer NCT04425616 | University Hospital Southampton NHS Foundation Trust | N/A |
| Terminated | Helmet CPAP Versus HFNC in COVID-19 NCT04395807 | Lund University | N/A |
| Completed | SARS-CoV-2 Associated Respiratory Failure Recovery (COVID-19 CAir) NCT04365595 | University of Zurich | — |
| Completed | COVID-19 in Pain Perspective NCT04454333 | Sisli Hamidiye Etfal Training and Research Hospital | — |
| Completed | Using GM-CSF as a Host Directed Therapeutic Against COVID-19 NCT04400929 | Singapore General Hospital | Phase 2 |
| Unknown | Evaluation of an Alternative Method of Obtaining Viral RNA for the Detection of SARS-CoV-2 Virus Using PCR NCT04468217 | Neurognos | — |
| Completed | Impact of COVID-19 Pandemic on Perceived Exercise Benefits and Barriers NCT04412278 | Okan University | — |
| Unknown | Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Dis NCT04408326 | Guy's and St Thomas' NHS Foundation Trust | — |
| Completed | Physical Activity Levels of Hypertensive and Healthy Individuals Under Social Isolation During the COVID-19 Pa NCT04583345 | Ebru Calik Kutukcu | — |
| Completed | Prevalence of Critical Forms of CoVid-19 in Patients With Chronic Respiratory Disease NCT04407169 | Central Hospital, Nancy, France | — |
| Completed | COVID-19 Blood Pressure Endothelium Interaction Study (OBELIX) NCT04409847 | NHS Greater Glasgow and Clyde | — |
| Unknown | Somerset and South Essex Coronavirus Antigen Testing NCT04403906 | Somerset NHS Foundation Trust | N/A |
| Withdrawn | Effects of Nicotinamide Riboside on the Clinical Outcome of Covid-19 in the Elderly NCT04407390 | University of Copenhagen | Phase 2 |
| Completed | The Prevalence of Pulmonary Hypertension in Patients With COVID-19. NCT04459364 | Attgeno AB | — |
| Unknown | COVIDAR - Arrhythmias in COVID-19 NCT04437901 | Hospital Clinic of Barcelona | — |
| Completed | Ivermectin as a Novel Therapy in COVID-19 Treatment NCT04403555 | Tanta University | Phase 2 / Phase 3 |
| Unknown | Mechanisms of Multi-organ Failure in COVID-19 NCT04399603 | Imperial College London | — |
| Unknown | High Versus Low LMWH Dosages in Hospitalized Patients With Severe COVID-19 Pneumonia and Coagulopathy NCT04408235 | Azienda Ospedaliero-Universitaria di Modena | Phase 3 |
| Completed | Epidemiology of Acute Kidney Injury in COVID19 Disease in United Kingdom NCT04407156 | University Hospitals of Derby and Burton NHS Foundation Trust | — |
| Unknown | Epidemiologic, Clinical, Molecular Characteristics of Hospital Employees With or Without Covid-19 Infection NCT04451577 | Istituto Clinico Humanitas | — |
| Completed | Seroepidemiological Study of SARS-CoV-2 (COVID-19) Infection in Population Subgroups in the State of São Paulo NCT04408014 | Butantan Institute | — |
| Unknown | Ivermectin in Treatment of COVID-19 NCT04445311 | Zagazig University | Phase 2 / Phase 3 |
| Completed | Dipyridamole to Prevent Coronavirus Exacerbation of Respiratory Status (DICER) in COVID-19 NCT04391179 | University of Michigan | Phase 2 |
| Completed | Prophylactic Ivermectin in COVID-19 Contacts NCT04422561 | Zagazig University | Phase 2 / Phase 3 |
| Terminated | A Phase 2 Study to Evaluate Axatilimab for Hospitalized Participants With Respiratory Involvement Secondary to NCT04415073 | Syndax Pharmaceuticals | Phase 2 |
| Completed | The COVID-19 Disease and CARdiac Events Study NCT04438993 | NHS Lanarkshire | — |
| Completed | Tele-based Psychological Emotional Support for Informal CARegivers of COVID-19 Patients in Intensive Care NCT04409821 | Rigshospitalet, Denmark | N/A |
| Completed | A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 NCT04402060 | Apellis Pharmaceuticals, Inc. | Phase 1 / Phase 2 |
| Terminated | Colchicine in Patients With Mild and Severe Coronavirus Disease NCT04367168 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | Phase 2 |
| Terminated | Incline Positioning in COVID-19 Patients for Improvement in Oxygen Saturation NCT04344561 | Johns Hopkins University | N/A |
| Completed | The Impact of COVID-19 Pandemic on Critical Limb Threatening Ischemia and Emergency Vascular Practice NCT04452682 | Mansoura University | — |
| Unknown | Coagulopathy in COVID19 - A Multi-Centre Observational Study in UK NCT04405232 | Imperial College London | — |
| Completed | Does Quality of Life Decline During the COVID-19 Pandemic and Can we Change Behaviour to Improve Poor Quality NCT04522128 | University of Manchester | N/A |
| Completed | COVID19 Versus H1N1: Radiological Challenge During Next Influenza Season Rising NCT04433039 | Alexandria University | — |
| Terminated | PRE-VENT Study in Hospitalized Patients With Severe COVID-19 With or Without Cancer NCT04404361 | CTI BioPharma | Phase 2 |
| Unknown | Cardiac Imaging in SARS-CoV-2 (COVID-19) NCT04403607 | NHS Greater Glasgow and Clyde | — |
| Completed | Determination of Acute Encephalopathy Predictors in Patients With COVID-19 NCT04405544 | State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia | N/A |
| Unknown | Evaluation of a Remote Monitoring Smartphone Application and Care Model of COVID-19 Patients in the Community NCT04399109 | Dr Sze-Yuan Ooi | N/A |
| Unknown | COVID-19 Thales Thermography Triage : Thermal Camera Feasibility Study NCT04397380 | NHS Greater Clyde and Glasgow | — |
| Completed | The Impact of COVID-19 Outbreak on Trans-population's Health in Italy NCT04448418 | Unita Complessa di Ostetricia e Ginecologia | — |
| Completed | PROTECT-ASUC: Covid-19 Pandemic Response Of assessmenT, EndosCopy and Treatment in Acute Severe Ulcerative Col NCT04411784 | Hull University Teaching Hospitals NHS Trust | — |
| Completed | A Research Study to Evaluate the Benefits of a Self-management Booklet to Promote Wellbeing During the COVID-1 NCT04408157 | King's College London | N/A |
| Completed | Antibody Detection in COVID-19 Cured Patients (SARS-CoV-2-CZ-Immunity) NCT04453280 | Institute of Health Information and Statistics of the Czech Republic | — |
| Unknown | Effectiveness and Safety of Convalescent Plasma Therapy on COVID-19 Patients With Acute Respiratory Distress S NCT04380935 | Indonesia University | Phase 2 / Phase 3 |
| Completed | Pediatric Acute and Critical Care COVID-19 Registry of Asia NCT04395781 | KK Women's and Children's Hospital | — |
| Terminated | Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms NCT04382391 | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | N/A |
| Completed | Detection of Covid-19 in Tissue Samples of Orthopedic Origin NCT04916561 | Centre de l'arthrose, Paris | — |
| Unknown | SARS-CoV 2 in Personal Protective Equipment NCT04398043 | Hospital de Clinicas José de San Martín | — |
| Completed | Predicting Favorable Outcomes in Hospitalized Covid-19 Patients NCT04570488 | NYU Langone Health | — |
| Completed | Oral Health and Psychosocial Factors During the Covid-19 Pandemic NCT04381273 | Heidelberg University | — |
| Completed | COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss NCT04395144 | Hôpital de Verdun | N/A |
| Completed | Clinical Epidemiology and Characteristics Of Covid-19 Cases Occurred In A Lymphoma Setting In The First Epidem NCT04386512 | Versailles Hospital | — |
| Completed | Patients Perspectives on Discontinuation of Their Fertility Treatment Due to the COVID-19 Pandemic NCT04396210 | University Hospital, Ghent | — |
| Withdrawn | The Role of Adaptive Immunity in COVID-19 Associated Myocardial Injury NCT04340921 | Barts & The London NHS Trust | — |
| Completed | Statin Therapy and COVID-19 Infection NCT04407273 | Institut Investigacio Sanitaria Pere Virgili | — |
| Completed | Facial Hair, PPE and COVID-19 NCT04579627 | Royal Cornwall Hospitals Trust | — |
| Unknown | Prone Positioning and High-flow Nasal Cannula in COVID-19 Induced ARDS NCT04391140 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Completed | Myeloproliferative Neoplasms (MPN) and COVID-19 NCT04385160 | FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS | — |
| Completed | Hydroxychloroquine Efficacy and Safety in Preventing SARS-CoV-2 Infection and COVID-19 Disease Severity During NCT04410562 | Barcelona Institute for Global Health | Phase 3 |
| Completed | Weight-Adjusted vs Fixed Low Doses of Low Molecular Weight Heparin For Venous Thromboembolism Prevention in CO NCT04373707 | Central Hospital, Nancy, France | Phase 4 |
| Completed | Obesity and Mortality of Critically Ill Patients With COVID-19 NCT04425213 | Central Hospital, Nancy, France | — |
| Unknown | Echocardiography in Critically-ill Patients With COVID-19 Pneumonia NCT04414410 | Hospital Ambroise Paré Paris | — |
| Completed | Increased Risk of SARS-CoronaVirus-2 (SARS-CoV-2) Infection Associated With Endoscopy (DECORE Study) NCT04401033 | Hospital del Rio Hortega | — |
| Unknown | Post Covid-19 Cardiopulmonary and Immunological Changes NCT04388436 | Mansoura University | — |
| Completed | The Role of a Private Hospital in Hong Kong Amid COVID-19 Pandemic NCT04416061 | Hong Kong Sanatorium & Hospital | — |
| Completed | Treatment of Covid-19 Associated Pneumonia With Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cel NCT04382547 | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | Phase 1 / Phase 2 |
| Unknown | The Utility of Bedside Lung Ultrasonography on Diagnosis of COVID-19 NCT04399681 | Kanuni Sultan Suleyman Training and Research Hospital | N/A |
| Terminated | Safety and Efficacy of Tocilizumab in Moderate to Severe COVID-19 With Inflammatory Markers NCT04403685 | Beneficência Portuguesa de São Paulo | Phase 3 |
| Recruiting | Novel Regimens in COVID-19 Treatment NCT04382846 | Tanta University | Phase 3 |
| Completed | Detection of COVID-19 (SARS-CoV-2) in the Semen of COVID+ Patients (Positive RT-PCR on a Nasopharyngeal Swab) NCT04460534 | GCS Ramsay Santé pour l'Enseignement et la Recherche | N/A |
| Withdrawn | Subcutaneous Sarilumab vs Placebo in Hospitalized Patients With Respiratory Distress Caused by COVID 19 NCT07196306 | BayCare Health System | Phase 2 |
| Withdrawn | OUTpatient Treatment of COVID-19 in Patients With Risk Factor for Poor Outcome NCT04365582 | Fondation Hôpital Saint-Joseph | Phase 3 |
| Terminated | Early CPAP in COVID-19 Confirmed or Suspected Patients NCT04390191 | Icahn School of Medicine at Mount Sinai | N/A |
| Withdrawn | Clinical Trial of Allogeneic Mesenchymal Cells From Umbilical Cord Tissue in Patients With COVID-19 NCT04366271 | Hospital Infantil Universitario Niño Jesús, Madrid, Spain | Phase 2 |
| Suspended | BAttLe Against COVID-19 Using MesenchYmal Stromal Cells NCT04348461 | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | Phase 2 |
| Unknown | Collection of Coronavirus COVID-19 Outbreak Samples in New South Wales NCT04383652 | Kirby Institute | — |
| Completed | Seroprevalence of SARS-Cov-2 Antibodies in Children NCT04347408 | Queen's University, Belfast | — |
| Terminated | Innovative Tool to Limit Spread of COVID 19 in Residential Aged Care Facilities NCT04377165 | The University of Queensland | N/A |
| Completed | HSS Covid-19 Antibody Serology Among Surgeons & Anesthesiologists NCT04389294 | Hospital for Special Surgery, New York | N/A |
| Unknown | Drug Safety and the Occurrence of Complications During Hospitalization in Patients With COVID-19 NCT04374110 | National Institute of Cardiology, Warsaw, Poland | — |
| Unknown | Low Dose Radiotherapy in COVID-19 Pneumonia NCT04390412 | Shahid Beheshti University of Medical Sciences | Phase 1 / Phase 2 |
| Completed | Convalescent Plasma for Patients With COVID-19 NCT04385199 | Henry Ford Health System | Phase 2 |
| Terminated | Novel Agents for Treatment of High-risk COVID-19 Positive Patients NCT04374019 | Susanne Arnold | Phase 2 |
| Completed | The New Silicone N99 Half-Piece Respirator NCT04454606 | Bangkok Metropolitan Administration Medical College and Vajira Hospital | N/A |
| Completed | Awake Prone Positioning and Oxygen Therapy in Patients With COVID-19 NCT04407468 | Hospital General San Juan del Rio | — |
| Withdrawn | Combination Therapy With Camostat Mesilate + Hydroxychloroquine for COVID-19 NCT04338906 | Heinrich-Heine University, Duesseldorf | Phase 4 |
| Terminated | Efficacy and Safety of Novel Treatment Options for Adults With COVID-19 Pneumonia NCT04345289 | Thomas Benfield | Phase 3 |
| Unknown | Verification of Alternative Do-it-yourself Equipment Respirators for the COVID-19 Personal Protective Equipmen NCT04375774 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Withdrawn | The LEAD COVID-19 Trial: Low-risk, Early Aspirin and Vitamin D to Reduce COVID-19 Hospitalizations NCT04363840 | Louisiana State University Health Sciences Center in New Orleans | Phase 2 |
| Unknown | COVID-19, bLOod Coagulation and Thrombosis NCT04388657 | Ramsay Générale de Santé | — |
| Completed | Vitamin D Levels in SARS-CoV-2: Do Current Adequacy Thresholds Reflect Clinical Risk? Insights From a Large Tu NCT04394390 | Bursa City Hospital | — |
| Withdrawn | In-vitro Diagnostic Test to Predict COVID-19 Mortality and Disease Severity NCT04368897 | Applied Biology, Inc. | — |
| Terminated | Transfusion of Convalescent Plasma for the Early Treatment of Patients With COVID-19 NCT04393727 | Azienda Ospedaliero, Universitaria Pisana | Phase 2 |
| Unknown | COVID-EC Study: Clinical Characteristics of Patients With COVID-19 in Guayaquil, Ecuador NCT04362969 | Hospital San Carlos, Madrid | — |
| Terminated | Evaluation of SARS-CoV-2 (COVID-19) Antibody-containing Plasma thErapy NCT04361253 | Brigham and Women's Hospital | Phase 3 |
| Terminated | MSCs in COVID-19 ARDS NCT04371393 | Icahn School of Medicine at Mount Sinai | Phase 3 |
| Completed | Neurologic Manifestations of COVID 19 in Children NCT04379089 | University of Pittsburgh | — |
| Unknown | SEVERITY SCORE FOR COVID-19 PNEUMONIA NCT04372199 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | COVID-19 : Neutralizing Human Monoclonal Antibodies Against SARS-Cov-2 NCT04354766 | Hospices Civils de Lyon | — |
| Unknown | International Lung UltraSound Analysis (ILUSA) Study NCT04353141 | KU Leuven | — |
| Completed | COVID-19 and Obstetric Transmission NCT04418557 | University Hospitals Cleveland Medical Center | — |
| Unknown | Radiographic Findings and Their Temporal Changes in COVID-19 Positive Changes Patients: A Prospective Study NCT04368871 | Max Healthcare Insititute Limited | — |
| Unknown | Monitoring COVID-19 Patients' Lung Fluid Using Impedance Technique NCT04406493 | Hillel Yaffe Medical Center | N/A |
| Terminated | Preventing COVID-19 Complications With Low- and High-dose Anticoagulation NCT04345848 | University Hospital, Geneva | Phase 3 |
| Completed | Avdoralimab an Anti-C5aR Antibody, in Patients With COVID-19 Severe Pneumonia ( FORCE ) NCT04371367 | Assistance Publique Hopitaux De Marseille | Phase 2 |
| Completed | A Single-blinded, Randomized, Placebo Controlled Phase II Trial of Prophylactic Treatment With Oral Azithromyc NCT04369365 | Prof. Dr. Matthias Preusser | Phase 2 |
| Unknown | Obstructive Sleep Apnea & Covid-19 Outcomes NCT04363333 | Koç University | — |
| Completed | Full Dose Heparin Vs. Prophylactic Or Intermediate Dose Heparin in High Risk COVID-19 Patients NCT04401293 | Northwell Health | Phase 3 |
| Unknown | Max Ivermectin- COVID 19 Study Versus Standard of Care Treatment for COVID 19 Cases. A Pilot Study NCT04373824 | Max Healthcare Insititute Limited | N/A |
| Completed | imPROving prenaTal carE During ConfinemenT NCT04368832 | Central Hospital, Nancy, France | — |
| Unknown | To Study the Clinical Characteristics and Treatment Outcome of COVID-19 Patients Admitted in Hospitals of Max NCT04367064 | Max Healthcare Insititute Limited | — |
| Completed | "Investigation of the Relationship Between New Coronary Virus Disease (COVID-19) and Anxiety and Depressive Sy NCT04384887 | Kanuni Sultan Suleyman Training and Research Hospital | — |
| Unknown | Senicapoc in COVID-19 Patients With Severe Respiratory Insufficiency NCT04594668 | University of Aarhus | Phase 2 |
| Completed | Drug Management of Rheumatoid Arthritis in Covid-19 Context : Impact on Therapeutic De-escalation NCT04393233 | University Hospital, Brest | — |
| Completed | Evaluation of Antibody Tests for COVID-19 NCT04360954 | Washington University School of Medicine | — |
| Completed | Post Discharge After Surgery Virtual Care With Remote Automated Monitoring Technology (PVC-RAM) Trial NCT04344665 | Population Health Research Institute | N/A |
| Completed | COVID-19: Herd Immunity Study in the Czech Republic NCT04401085 | Institute of Health Information and Statistics of the Czech Republic | — |
| Completed | COVID-19 Among Egyptian Health Care Providers NCT04357431 | Assiut University | — |
| Completed | Nebulised Rt-PA for ARDS Due to COVID-19 NCT04356833 | University College, London | Phase 2 |
| Recruiting | Long-term Impact of Infection With Novel Coronavirus (COVID-19) NCT04362150 | University of California, San Francisco | — |
| Terminated | Saved From COVID-19 - Chloroquine (CQ) Prophylaxis for Health Care Workers at Risk for COVID NCT04349371 | Columbia University | Phase 2 |
| Active Not Recruiting | Assessing the Safety of Pregnancy In the CoRonavirus (COVID-19) pandEmic NCT04388605 | University of California, San Francisco | — |
| Completed | COVID-19 Serology Screening and Strict Protocol in the Endoscopy Unit NCT04374123 | Instituto Ecuatoriano de Enfermedades Digestivas | — |
| Unknown | Precision Immunology to Determine the Immune Response in Patients With COVID-19 NCT04360733 | University of Bonn | — |
| Terminated | Estrogen Patch for COVID-19 Symptoms NCT04359329 | Sharon Nachman | Phase 2 |
| Completed | Efficacy of Faviprevir in COVID-19 Treatment NCT04351295 | Tanta University | Phase 2 / Phase 3 |
| Completed | ACCESS A Master Digital Surveillance Protocol for COVID-19 NCT04363268 | Medable Inc. | — |
| Active Not Recruiting | First Level Socio-geriatric Evaluation: ESOGER Databank NCT04393649 | Jewish General Hospital | — |
| Completed | Efficacy of Convalescent Plasma Therapy in Severely Sick COVID-19 Patients NCT04346446 | Institute of Liver and Biliary Sciences, India | Phase 2 |
| Completed | COVID-19 Impact on Rheumatic Patients NCT04407299 | Cairo University | — |
| Completed | Evaluation of the Relationship Between Zinc Vitamin D and b12 Levels in the Covid-19 Positive Pregnant Women NCT04407572 | Kanuni Sultan Suleyman Training and Research Hospital | — |
| Completed | Glycaemia and Cardiac Function in Patients With COVID-19 NCT04410718 | Steno Diabetes Center Copenhagen | — |
| Withdrawn | The Use of Tadalafil in Confirmed COVID-19 Pneumonia. NCT04946162 | Santa Barbara Cottage Hospital | Phase 4 |
| Completed | Patient Recovery From Heart Surgery During the Covid-19 Pandemic NCT04366167 | Barts & The London NHS Trust | — |
| Terminated | Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVI NCT04335786 | Radboud University Medical Center | Phase 4 |
| Unknown | Pilot Study on Cytokine Filtration in COVID-19 ARDS NCT04361526 | Manuel Castellà | N/A |
| Completed | Impact of Tele-interventions During the COVID-19 Pandemic in Patients With Diabetes Mellitus NCT04344210 | Federal University of Rio Grande do Sul | N/A |
| Completed | Development of a Molecular Diagnostic Strategy for SARS-CoV2 Based on Saliva in the Context of the COVID-19 Pa NCT04367545 | University Hospital, Rouen | N/A |
| Completed | Imaging Feature of SARS-CoV2 Infection NCT04394026 | Francesco De Cobelli | — |
| Completed | Efficacy of Chloroquine or Hydroxychloroquine in Treating Pneumonia Caused by SARS-Cov-2 - COVID-19 NCT04420247 | Centro de Estudos e Pesquisa em Emergencias Medicas e Terapia Intensiva | Phase 3 |
| Recruiting | A Study to Explore the Role of Gut Flora in COVID-19 Infection NCT04359836 | ProgenaBiome | — |
| Completed | Pediatric Acute Kidney Injury in COVID-19 NCT04466306 | Children's Healthcare of Atlanta | — |
| Not Yet Recruiting | Angiotensin Converting Enzyme Inhibitors in Treatment of Covid 19 NCT04345406 | Tanta University | Phase 3 |
| Completed | Assessment of Exam Findings in Coronavirus Disease 2019 (COVID-19) With Point-of-Care Ultrasonography (POCUS) NCT04339998 | University of Minnesota | — |
| Completed | COVID-19: Investigation of Transmission and Immunisation Among Hospital Staff NCT04346186 | Herlev Hospital | — |
| Completed | Validation of an Immunochromatographic Assay for IgG/IgM Antibodies to 2019- nCoV NCT04434417 | European Institute of Oncology | — |
| Completed | Prevalence of Covid-19 in Children Admitted to Paediatric Emergency Departments During the Pandemic Period in NCT04336761 | University Hospital, Lille | — |
| Active Not Recruiting | COVID-19 Biorepository NCT04568148 | University of Kansas Medical Center | — |
| Unknown | Efficacy of Ivermectin in COVID-19 NCT04392713 | Combined Military Hospital, Pakistan | N/A |
| Completed | Study of the Immunity of Patients With Lung Cancer and COVID-19 Infection NCT04407143 | Fundación GECP | — |
| Completed | Kidney Involvement in COVID-19 Disease (COVKID) NCT04355624 | Centre Hospitalier Universitaire de Nice | — |
| Unknown | COVID-19 in Cancer Patients: Evaluation of Clinical Course and Impact on Oncological Care Including Biobanking NCT04408339 | Universitätsklinikum Hamburg-Eppendorf | — |
| Unknown | A Study to Assess the Virus RNA, and miRNA Levels Related to Viral Infection, and Inflammatory Response in Tea NCT04346160 | G. d'Annunzio University | — |
| Terminated | Observational Study of COVID-19 Treatment Efficacy NCT04369989 | OSF Healthcare System | — |
| Completed | COVID-19 Pandemic Burden in Severe Mental Disease Patients NCT04357769 | Federico II University | — |
| Completed | Sarilumab for Patients With Moderate COVID-19 Disease NCT04359901 | Westyn Branch-Elliman | Phase 2 |
| Completed | Early Risk Stratification of Patient Hospitalized for SARS-CoV2 Infection: Critical COVID-19 France CCF NCT04344327 | French Cardiology Society | — |
| Completed | Convalescent Plasma in the Treatment of COVID 19 NCT04343261 | Trinity Health Of New England | Phase 2 |
| Completed | COVID-19 Pandemic and Female Sexual Behavior NCT04374422 | Acibadem University | — |
| Unknown | European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO NCT04366921 | Maastricht University Medical Center | — |
| Completed | Double Therapy With IFN-beta 1b and Hydroxychloroquine NCT04350281 | The University of Hong Kong | Phase 2 |
| Terminated | Intensive Care Associated Complications and Outcome of Acute Respiratory Distress Syndrome Due to COVID-19 NCT04397172 | Insel Gruppe AG, University Hospital Bern | — |
| Completed | Impact of the Double-Trunk Mask on Oxygenation Titration in COVID-19 NCT04346420 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Unknown | Assessment of Chilbains Occuring During Covid-19 Infection NCT04344119 | Centre Hospitalier Universitaire de Nice | — |
| Terminated | Convalescent Plasma vs. Standard Plasma for COVID-19 NCT04344535 | Stony Brook University | Phase 1 / Phase 2 |
| Completed | Point Of Care UltraSonography for Risk-stratification of COVID-19 Patients NCT04338100 | University Hospital, Angers | — |
| Completed | Coronavirus 2019 (COVID-19)- Using Ascorbic Acid and Zinc Supplementation NCT04342728 | The Cleveland Clinic | N/A |
| Completed | COVID-19 Community Research Partnership NCT04342884 | Wake Forest University Health Sciences | — |
| Withdrawn | Intermediate IND Severe Illness COVID-19 CP NCT04411602 | Henry Ford Health System | Phase 1 |
| Completed | COVID-19 Registry Rhineland-Palatinate (Germany) NCT04335188 | IHF GmbH - Institut für Herzinfarktforschung | — |
| Recruiting | COVID-19 in Hospitalised Norwegian Children - Risk Factors, Outcomes and Immunology NCT04335773 | University Hospital, Akershus | — |
| Completed | The GCO-002 CACOVID-19 Cohort: a French Nationwide Multicenter Study of COVID-19 Infected Cancer Patients NCT04397575 | Federation Francophone de Cancerologie Digestive | — |
| Unknown | Impact of Angiotensin II Receptor Blockers Treatment in Patients With COVID 19 (COVID-ARA2) NCT04337190 | University Hospital, Angers | — |
| Completed | Surgery During Covid-19: The Role of Asymptomatic Patients, a Survey NCT04344197 | University of Rome Tor Vergata | — |
| Completed | Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment NCT04339634 | Tabula Rasa HealthCare | — |
| Unknown | Risk Prediction and Therapy Monitoring in Patients With SARS-Cov-2 Infection / COVID 19 NCT04456075 | Heidelberg University | — |
| Unknown | A Human Clinical Study to Collect Calibration and Performance Data for the RBA-2 Device NCT04357977 | Kaligia Biosciences, LLC | — |
| Completed | COVID-19 Immune Repertoire Sequencing NCT04368143 | Institute of Tropical Medicine, Belgium | — |
| Completed | Become of Patients Infected or Suspected of Being Infected by Covid-19 and Supported by the GHPSJ and the Esta NCT04365530 | Fondation Hôpital Saint-Joseph | — |
| Withdrawn | Hydroxychloroquine Treatment of Healthcare Workers With COVID19 Illness at Montefiore NCT04350450 | Montefiore Medical Center | Phase 2 |
| Completed | Familial Mediterranean Fever and Behçet: Analysis Before and After Covid19 Pandemic NCT04403438 | Istanbul University | — |