Clinical Trials Directory

Trials / Sponsors / Federation Francophone de Cancerologie Digestive

Federation Francophone de Cancerologie Digestive

Academic / Other · 62 registered clinical trials12 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingProspective National Cohort Evaluating Prognostic Factors for Efficacy of Fruquintinib Treatment in Patients W
Metastatic Colorectal Cancer (CRC), Antineoplastic Agents, Immunological, VEGFR-TKI
N/A2026-03-01
Not Yet RecruitingSecond-line Doublet Chemotherapy (FOLFOX or FOLFIRI) Plus Fruquintinib Versus Doublet Chemotherapy (FOLFOX or
Metastatic Colorectal Carcinoma (mCRC)
Phase 22025-12-31
RecruitingTrifluridine/Tipiracil + Fruquintinib Versus Trifluridine/Tipiracil Alone for Metastatic Oeso-gastric Adenocar
Metastatic Oesogastric Adenocarcinoma
Phase 32025-12-15
Not Yet RecruitingPErioperative CISGEM + Rilvegostomig in High-Risk Resectable Intra Hepatic CholangioCarcinoma
Intrahepatic Cholangiocarcinoma (Icc)
Phase 22025-10-30
Not Yet Recruiting5-fluorouracil Plus Panitumumab (Anti-EGFR) and Sotorasib (KRAS G12C Inhibitor) in First-line Treatment of Pat
Colorectal Carcinoma, KRAS G12C Mutation, Unresectable Colorectal Cancer
Phase 22025-08-31
RecruitingA French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers
Hepatocholangiocarcinoma, Fibrolamellar Carcinoma, Hepatic Epithelioid Hemangioendothelioma
2024-03-26
RecruitingPhase III Study Evaluating Induction Chemotherapy Followed by Chemoradiotherapy Compared to Standard Chemoradi
Anal Cancer
Phase 32024-02-26
RecruitingProspective National Cohort Evaluating Predictive Biomarkers of Resistance to Immunotherapy in Patients With M
Colorectal Cancer Metastatic, Microsatellite Instability-High Colorectal Cancer
2024-02-12
CompletedStudy Evaluating the Benefit of Adding Ipilimumab to the Combination of Atezolizumab and Bevacizumab in Patien
HCC - Hepatocellular Carcinoma, Metastatic Cancer, Metastatic Tumor
Phase 2 / Phase 32023-03-09
RecruitingEncorafenib Plus Cetuximab in a Neoadjuvant Setting in Patients With BRAF Mutation Localised Colon or Upper Re
Colorectal Cancer, BRAF V600E Mutation Positive
Phase 22023-02-13
RecruitingCohort of Tumors With POLE/D1 Mutation
Tumors, POLE Exonuclease Domain Mutation, POLD1 Gene Mutation
2021-10-05
UnknownChemotherapy and Immunotherapy as Treatment for MSS Metastatic Colorectal Cancer With High Immune Infiltrate
Colorectal Cancer Metastatic, High Immune Infiltrate, Microsatellite Stable
Phase 22021-04-06
UnknownStudy to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox, Bevacizumab and Atez
Metastatic Colorectal Cancer, pMMR, MSS
Phase 22020-10-07
CompletedThe GCO-002 CACOVID-19 Cohort: a French Nationwide Multicenter Study of COVID-19 Infected Cancer Patients
Cancer, COVID, Solid Tumor
2020-04-03
Active Not RecruitingClinical Trial Evaluating FOLFIRI + Durvalumab vs FOLFIRI + Durvalumab and Tremelimumab in Second-line Treatme
Gastric Adenocarcinoma, Gastric Cancer
Phase 22019-07-17
CompletedNal-iri/lv5-fu Versus Paclitaxel as Second Line Therapy in Patients With Metastatic Oesophageal Squamous Cell
Squamous Cell Carcinoma
Phase 22019-03-07
Active Not RecruitingSecond-Line Chemotherapy With Ramucirumab +/- Paclitaxel in Elderly Advanced Gastric or Gastroesophageal Junct
Stomach Cancer, Stomach Neoplasm, Gastric Cancer
Phase 22018-11-16
CompletedFirst Line Metastatic Pancreatic Cancer : 5FU/LV+Nal-IRI, Gemcitabine+Nab-paclitaxel or a Sequential Regimen o
Metastatic Pancreatic Cancer
Phase 22018-11-16
CompletedFOLFOX + Panitumumab According to a "Stop and go" Strategy With a Reintroduction Loop After Progression on Flu
Metastatic Colorectal Cancer
Phase 22018-04-26
CompletedStandard Chemotherapy vs Immunotherapie in 2nd Line Treatment of MSI Colorectal Mestastatic Cancer
Metastatic Colorectal Cancer, MSI
Phase 22018-04-24
UnknownSurvival and Description of Care for Patients With Degenerate Vaterian Ampulloma
Ampullary Adenocarcinoma
2017-07-07
Active Not RecruitingNational Cohort of Colorectal Cancers With Microsatellite Instability
Colorectal Cancer, Microsatellite Instability
2017-03-22
CompletedPHASE III RANDOMISED TRIAL to EVALUATE FOLFOX with or WITHOUT DOCETAXEL (TFOX) AS 1st LINE CHEMOTHERAPY for LO
OESOPHAGO-GASTRIC CARCINOMA
Phase 32016-12-19
RecruitingSystemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy
Colorectal Neoplasms
Phase 32016-12-01
TerminatedDe-escalation Chemotherapies Versus Escalation in Non Pre-treated Unresectable Patients With Metastatic Colore
Colorectal Neoplasms
Phase 22016-09-01
UnknownStudy of the Practice of Debiri in France
Colorectal Adenocarcinoma, Hepatic Metastases
2016-02-03
CompletedEfficacy and the Safety of Regorafenib in Patients Aged More Than 70 Years With a Metastatic Colorectal Adenoc
Colorectal Adenocarcinoma
Phase 22016-01-01
CompletedRadiochemotherapy With Panitumumab in the Localised Epidermoid Carcinoma of the Anus
Epidermoid Carcinoma, Anus
Phase 1 / Phase 22016-01-01
CompletedFIrst Line Treatment of Metastatic Pancreatic Cancer: Sequential Nab-paclitaxel + Gemcitabine/FOLFIRI.3 VS Nab
Metastatic Pancreatic Cancer
Phase 22015-11-01
CompletedAflibercept +/- LV5FU2 in First Line of Non-resectalbe Metastatic Colorectal Cancers
Colorectal Neoplasms
Phase 22015-05-01
CompletedFirst-line Metastatic Pancreatic Cancer : FOLFIRINOX +/- LV5FU2 in Maintenance Versus Firgem
Metastatic Pancreatic Cancer
Phase 22015-01-12
CompletedChemoembolisation of Hepatocellular Carcinomas Not Subject to Interventive Care by Idarubicin-loaded Beads - I
Liver Cancer
Phase 22015-01-01
TerminatedA Study Evaluating Lanreotide as Maintenance Therapy in Patients With Non-Resectable Duodeno-Pancreatic Neuroe
Metastatic/Locally Advanced, Non-resectable, Duodeno-pancreatic Neuroendocrine Tumours
Phase 2 / Phase 32015-01-01
RecruitingRandomised Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patie
Colonic Adenocarcinoma
Phase 32015-01-01
CompletedEfficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients
Metastatic Colorectal Cancer
Phase 22014-10-01
CompletedIntra-arterial Hepatic Beads Loaded With Irinotecan With Concomitant Chemotherapy With FOLFOX in Patients With
Colorectal Cancer With Non Resectable Hepatic Metastasis
Phase 22013-05-01
CompletedEverolimus After (Chemo)Embolization for Liver Metastases From Digestive Endocrine Tumors
Neuroendocrine Tumors, Hepatic Metastases, Metastases
Phase 22012-12-01
CompletedFirst Line Treatment by FOLFIRINOX for Patients With a Rectum Cancer With Synchronous Non Resectable Metastasi
Adenocarcinoma of Rectum
Phase 22012-04-01
Completed1st Line Chemotherapy Alone or With Bevacizumab in Treating Older Patients With Metastatic Colorectal Cancer
Colorectal Cancer
Phase 22011-07-01
CompletedFluorouracil, Cisplatin, Leucovorin Calcium, and Cetuximab in Treating Patients With Adenocarcinoma of the Sto
Adenocarcinoma of the Gastroesophageal Junction, Gastric Cancer
Phase 22011-06-01
CompletedGemcitabine Hydrochloride in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery
Pancreatic Cancer
Phase 22011-06-01
CompletedChemoembolization of the Liver With or Without Sunitinib Malate in Treating Patients With Liver Cancer
Liver Cancer
Phase 2 / Phase 32010-07-01
CompletedCombination Chemotherapy and Bevacizumab With or Without Bevacizumab Maintenance Therapy in Treating Patients
Colorectal Cancer
Phase 2 / Phase 32010-03-01
CompletedSorafenib Tosylate With or Without Pravastatin in Treating Patients With Liver Cancer and Cirrhosis
Liver Cancer
Phase 32010-02-01
TerminatedTemsirolimus in Treating Patients With Advanced Liver Cancer and Cirrhosis
Liver Cancer
Phase 22010-01-01
CompletedFollow-Up Care With or Without CEA Assessments in Patients Who Have Undergone Surgery for Stage II or Stage II
Colorectal Cancer
Phase 32009-09-01
WithdrawnSunitinib Malate and Combination Chemotherapy as Front-Line Therapy in Treating Patients With Metastatic Recta
Colorectal Cancer, Metastatic Cancer
Phase 22009-04-01
CompletedG-CSF in Preventing Neutropenia During First-Line Treatment With Chemotherapy and Bevacizumab in Patients With
Colorectal Cancer
Phase 22007-11-01
CompletedFluorouracil, Cisplatin, Cetuximab, and Radiation Therapy in Treating Patients With Esophageal Cancer That Can
Esophageal Cancer
Phase 1 / Phase 22007-07-01
CompletedCombination Chemotherapy and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer
Colorectal Cancer
Phase 22007-01-01
UnknownIrinotecan With or Without Capecitabine as Second-Line Therapy in Treating Older Patients With Progressive, Me
Colorectal Cancer
Phase 22006-06-01
CompletedCombination Chemotherapy With or Without Cetuximab in Treating Patients With Stage III Colon Cancer That Was C
Colorectal Cancer
Phase 32005-11-01
CompletedValidation Study of Linear Quantification of CD3+ Cells in Localized Colorectal Carcinomas
Metastatic Colorectal Cancer
2005-11-01
CompletedFluorouracil, Cisplatin, and Radiation Therapy or Gemcitabine and Oxaliplatin in Treating Patients With Nonmet
Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer
Phase 2 / Phase 32005-10-01
CompletedCombination Chemotherapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By Surg
Pancreatic Cancer
Phase 32005-10-01
UnknownFluorouracil and Irinotecan With or Without Leucovorin Compared With Observation in Treating Patients Who Have
Colorectal Cancer
Phase 32004-06-01
CompletedCombination Chemotherapy as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Neuroe
Gastrointestinal Carcinoid Tumor, Islet Cell Tumor, Neoplastic Syndrome
Phase 22004-05-01
CompletedCombination Chemotherapy as First-Line Therapy in Treating Older Patients With Metastatic Colorectal Cancer Th
Colorectal Cancer
Phase 32003-06-01
CompletedSurgery With or Without Radiation Therapy and Chemotherapy in Treating Patients With Esophageal Cancer
Esophageal Cancer
Phase 32002-05-01
CompletedGemcitabine With or Without Combination Chemotherapy and Radiation Therapy in Treating Patients With Nonmetast
Pancreatic Cancer
Phase 32000-03-01
CompletedRadiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III
Colorectal Cancer
Phase 31993-04-01
CompletedRadiation Therapy and Combination Chemotherapy With or Without Surgery in Treating Patients With Locally Advan
Esophageal Cancer
Phase 3