NCT04424017

Sero-prevalence of Coronavirus Disease 2019 (COVID-19) in Healthcare Workers

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,546 (actual)
• Sponsor: Egyptian Center for Research and Regenerative Medicine · Other Government
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The medical and paramedical staff of the front-line services are potentially exposed to SARS-CoV-2. Therefore, despite the application of standard protective measures, it is possible that a certain number of these personnel have already contracted SARS-CoV-2, including in its asymptomatic form. Serological testing in this context would be useful for deploying immune healthcare workers as to limit the risk of viral infection and transmission. Therefore, it is of utmost importance to prove that the serological response entails the production of neutralizing antibodies.

Conditions

• COVID
• Corona Virus Infection

Interventions

Type	Name	Description
BIOLOGICAL	Specific anti-SARS-CoV-2 antibodies	A serum sample needs to be collected from each participant upon recruitment into the investigation All samples will be tested by the rapid test (Artron, Artron Laboratories, Burnaby, Canada), IgM / IgG which is an antibody capture Immunochromatografac assay for simultaneous detection of IgM and IgG in serum or plasma for COVID -19 in samples. All samples will be tested for total Immunoglobulins and IgG in samples for COVID-19 virus by Ortho clinical diagnostics chemiluminescent technique (Ortho, Raritan, USA).

Timeline

• Start date: 2020-06-07
• Primary completion: 2020-10-30
• Completion: 2020-10-30
• First posted: 2020-06-09
• Last updated: 2021-03-09

Locations

2 sites across 1 country: Egypt