Clinical Trials Directory

Trials / Terminated

TerminatedNCT04389450

Double-Blind, Multicenter, Study to Evaluate the Efficacy of PLX PAD for the Treatment of COVID-19

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Group Phase II Study to Evaluate the Efficacy and Safety of Intramuscular Injections of PLX PAD for the Treatment of Severe COVID-19

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
66 (actual)
Sponsor
Pluristem Ltd. · Industry
Sex
All
Age
40 Years – 80 Years
Healthy volunteers
Not accepted

Summary

This clinical trial will examine if a new treatment of Mesenchymal-like Adherent stromal Cells (called PLX-PAD) can help patients intubated and mechanically ventilated due to COVID-19 to recover more quickly with less complications.

Conditions

Interventions

TypeNameDescription
BIOLOGICALPLX-PADPLX-PAD, allogeneic ex vivo expanded placental mesenchymal-like adherent stromal cells
BIOLOGICALPlaceboPlacebo solution for injection

Timeline

Start date
2020-10-01
Primary completion
2021-05-17
Completion
2023-06-07
First posted
2020-05-15
Last updated
2024-08-30

Locations

13 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04389450. Inclusion in this directory is not an endorsement.

Double-Blind, Multicenter, Study to Evaluate the Efficacy of PLX PAD for the Treatment of COVID-19 (NCT04389450) · Clinical Trials Directory