Constipation

532 registered clinical trials studyying Constipation — 64 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Akk09 in Adults With Constipation NCT07529457	Wecare Probiotics Co., Ltd.	N/A
Not Yet Recruiting	Rifaximin Treatment in Bloating Predominant Functional Bowel Disorders NCT07522255	Mahidol University	Phase 3
Recruiting	Probiotic Improve Constipation NCT07462481	Wecare Probiotics Co., Ltd.	N/A
Not Yet Recruiting	Effect of Preoperative Abdominal Effleurage on Postoperative Constipation NCT07344532	Ege University	N/A
Active Not Recruiting	Constipation in Children With Cerebral Palsy NCT07466914	Lokman Hekim University	—
Not Yet Recruiting	Preoperative Fish Oil PN and Prognosis After Constipation Surgery NCT07470892	Qianfoshan Hospital	—
Not Yet Recruiting	Randomized, Blinded, Placebo-Controlled Evaluation of BioAmicus Complete NCT07444008	NovoNatum Ltd	N/A
Not Yet Recruiting	The Auxiliary Effect of Artificial Intelligence in the Detection of Precancerous Lesions in Proximal Colon Can NCT07338643	Limian Er	—
Not Yet Recruiting	Soluble and Osmotic Fibre (SOLOS) Diet for Constipation NCT07388589	Singapore Institute of Technology	—
Not Yet Recruiting	Oat Milk for Laxation NCT07302542	Capital Medical University	N/A
Not Yet Recruiting	Radicle GI Health RDH™: A Study Assessing the Impact of Health and Wellness Products on Gastrointestinal (GI) NCT07230821	Radicle Science	N/A
Recruiting	Impact of the Inno Cleanse Dietary Supplement on Gut Health and Associated Variables in Healthy Men and Women NCT07215351	University of Memphis	N/A
Recruiting	Multi-strain Probiotic Effects on Self-Reported Constipation NCT07275866	Dr Anthony Hobson	N/A
Recruiting	Efficacy of LcS-Fermented Milk on Constipation-Related Symptoms in Filipino Adults NCT07083596	University of Santo Tomas	N/A
Not Yet Recruiting	Effect of Whole-body Vibration on Postmenopausal Constipation NCT07196761	Cairo University	N/A
Completed	Ear Massage Effect on Bowel Activity After Surgery NCT06862986	Mersin University	N/A
Not Yet Recruiting	Long-term Evaluation of Percutaneous Endoscopic Caecostomy in Refractory Constipation NCT07160192	Nantes University Hospital	—
Enrolling By Invitation	A Rapid Clinical Care Pathway to Care for Patients Affected by Chronic Constipation NCT07032376	University of Michigan	N/A
Recruiting	The Efficacy Evaluation of TCI604 Probiotic on Intestinal Function Improvement NCT07135362	TCI Co., Ltd.	N/A
Recruiting	Management of Dyssynergic Defecation NCT07225803	Mayo Clinic	N/A
Recruiting	A Study of Herbal Supplements in Cancer Survivors With Constipation NCT07091084	Memorial Sloan Kettering Cancer Center	N/A
Not Yet Recruiting	Prevalence of Functional Lower Urinary Tract Voiding Dysfunction in School-Aged Children NCT07067957	Tanta University	—
Recruiting	Effectiveness of Self-Administered Acupressure Intervention in Managing Constipation of Adult Psychiatric In-P NCT07039448	Hong Kong Metropolitan University	N/A
Not Yet Recruiting	Effectiveness of Self-administered Acupressure Intervention in Managing Constipation of Adult Psychiatric Out- NCT07039409	Hong Kong Metropolitan University	N/A
Recruiting	Impact of Weizmannia (Bacillus) Coagulans JBI-YZ6.3 on Gut Health and Fecal Microbiome Changes NCT07388264	Lindenwood University	N/A
Completed	The Effect of Abdominal Massage on Constipation NCT07402785	Firat Tukenmez	N/A
Not Yet Recruiting	A Trial of Actazin Versus PEG 3350 for Maintenance Therapy in Children With Constipation NCT06836024	Hamilton Health Sciences Corporation	Phase 2 / Phase 3
Recruiting	Assessing Tenapanor as a Treatment of CF-related Constipation. NCT06810167	Massachusetts General Hospital	Phase 3
Not Yet Recruiting	Spinal Stabilization Exercise Training in Women With Chronic Constipation NCT06941103	Özel Artı Disleksi Özel Eğitim ve Rehabilitasyon Merkezi	N/A
Recruiting	A Prospective Multicentre Real-world Assessment of the Efficacy of Danning Tablets in Alleviating Digestive Sy NCT06755671	Shanghai Hutchison Pharmaceuticals Limited	—
Recruiting	Effect of Pre-Surgery Constipation Podcast: A RCT NCT06877078	Central Jutland Regional Hospital	N/A
Not Yet Recruiting	CMTS4520 for Chronic Constipation in Adults NCT06832137	The Second Hospital of Nanjing Medical University	Phase 1 / Phase 2
Enrolling By Invitation	Enabling Microbiomics- Driven Personalized Nutrition NCT06657001	Mayo Clinic	—
Recruiting	A Study of Microbiome Transplantation for the Treatment of Constipation and/or Significant Bloating in Patient NCT06827977	The University of Texas Health Science Center, Houston	Phase 2
Enrolling By Invitation	Study of Transition in Real-life Experiences Affecting Micturition and Well-being in Adolescent Years NCT07339865	University Hospital, Ghent	—
Recruiting	To Evaluate the Safety and Efficacy of Pediococcus Acidilactici PA53 in Relieving Constipation in Adults NCT06761443	Wecare Probiotics Co., Ltd.	N/A
Not Yet Recruiting	CMTS4520-Assisted Washed Microbiota Transplantation for Chronic Constipation in Adults NCT06832176	The Second Hospital of Nanjing Medical University	Phase 1 / Phase 2
Recruiting	Comparison of Remimazolam and Propofol in Endoscopic Examinations and Treatments NCT06777758	Kaohsiung Veterans General Hospital.	Phase 4
Not Yet Recruiting	The Effect of Su-Jok Therapy Applied to the Elderly on Constipation Symptoms and Quality of Life NCT06817824	Hasan Kalyoncu University	N/A
Recruiting	Pelvic Health Rehabilitation After Breast and Gynecologic Cancer NCT06822582	Laval University	N/A
Not Yet Recruiting	Xuanhuang Runtong Tablet in the Treatment of Constipation (Yin-deficiency Type) NCT06740422	Beijing Hospital of Traditional Chinese Medicine	Phase 3
Not Yet Recruiting	Effect of Acupressure in The Management of Postmenopausal Constipation NCT06720077	Cairo University	N/A
Active Not Recruiting	Validation of a Novel Functional Food Designed to Meet the Nutritional Needs of People Living With Parkinson's NCT06697626	University of Ulster	N/A
Recruiting	Optimization of Postoperative Bowel Habits NCT06335797	Wake Forest University Health Sciences	N/A
Not Yet Recruiting	Ameliorating Effects and Mechanisms of TaVNS on Constipation in PD Patients. NCT06623591	Kezhong Zhang	N/A
Active Not Recruiting	Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks NCT07099222	University of Arizona	Phase 1 / Phase 2
Completed	Probiotics Alleviate Functional Constipation in Adults NCT06879587	Wecare Probiotics Co., Ltd.	N/A
Completed	Nursing Homes on Constipation and General Comfort NCT06788392	Giresun Huzurevi Yaşlı Bakım ve Rehabilitasyon Merkezi	N/A
Active Not Recruiting	Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders NCT06503978	Gut-Brain-Axis Therapeutics Inc.	Phase 2
Recruiting	Effects of Probiotics (BioKid LR - Contains Nine Different Species of Probiotics Bacteria Including L. Reuteri NCT06959758	Ferass Abu Hanna	Phase 4
Completed	Guideline to Implementation: A Rapid Clinical Care Pathway to Care for Patients Affected by Chronic Constipati NCT06352827	University of Michigan	N/A
Recruiting	Levofloxacin in the Treatment of Chronic Functional Constipation Associated With PIB(Peristaltic Contraction-I NCT06571097	Haifeng Lan	N/A
Not Yet Recruiting	Efficacy of Lacticaseibacillus Paracasei Strain Shirota on Clinical Manifestation of Functional Constipation i NCT06432608	University of Guadalajara	N/A
Recruiting	Investigation of the Effect of Manual Therapy and Pelvic Floor Exercises on Pelvic Floor Muscles NCT06494917	Istanbul Arel University	N/A
Completed	Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery NCT06159777	University Hospitals Cleveland Medical Center	Phase 4
Completed	Acute Effects of Abdominal Massage on Arterial Stiffness, Muscle Oxygenation and Exercise Capacity in Constipa NCT07352449	Gazi University	N/A
Recruiting	Probiotics for Alleviating Functional Constipation in Adults NCT06637397	Wecare Probiotics Co., Ltd.	N/A
Recruiting	The ReVo Study: Low-volume vs High-volume Rectal Irrigation NCT06100055	Guy's and St Thomas' NHS Foundation Trust	N/A
Recruiting	Efficacy of Acupuncture for the Treatment of Parkinson's Disease Related Constipation NCT06390761	Xi'an No.3 Hospital	N/A
Completed	Probiotics for Alleviating Chronic Constipation in Adults NCT07152795	Wecare Probiotics Co., Ltd.	N/A
Completed	MOWOOT Device Treatment for Adults With Chronic Constipation NCT04666155	usMIMA S.L.	N/A
Recruiting	Dairy Products to Your Gut and Brain NCT06311097	University of Copenhagen	N/A
Recruiting	Investigation of the Additional Effects of Aerobic Exercise Training to Abdominal Massage in Functional Consti NCT06298331	Hacettepe University	N/A
Unknown	Abdominal Massage and Kegel Exercises on Constipation and Quality of Life in Female Students NCT06290830	Ondokuz Mayıs University	N/A
Unknown	The Effect of Naldemedine on Opioid-induced Bowel Dysfunction NCT06334198	Asbjørn Mohr Drewes	Phase 2
Completed	Kombucha Tea for Improving Defecation in Patients With Schizophrenia- a Randomized Controlled Study NCT06502509	TsaoTun Psychiatric Center, Department of Health, Taiwan	N/A
Completed	Effectiveness of Bacillus Spore Probiotics in Reducing Constipation, Anorexia, and Slow Weight Gain in Childre NCT06154525	Anabio R&D	N/A
Unknown	Effectiveness of Non-invasive Neuromodulation for Intestinal Transit in Healthy Subjects NCT06294457	Universidad Europea de Madrid	N/A
Recruiting	The Effects of TTNS, TTNS Combined With PHUS, and Conventional Therapy With PHUS in the Treatment of PFC. NCT07077044	Hadassah Medical Organization	N/A
Recruiting	Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis NCT05989763	The University of Texas Health Science Center, Houston	N/A
Unknown	Technology-based Constipation Prevention Training NCT06234865	Mehmet Akif Ersoy University	N/A
Completed	Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial NCT06123195	University of Tennessee	N/A
Completed	The Effect of Constipation Insoles on the Management of Constipation NCT07339293	Istanbul Aydın University	N/A
Completed	Foot Reflexology and Abdominal Massage NCT06875349	Karadeniz Technical University	N/A
Completed	Combined Effects of Whole Body Vibration and Abdominal Binders on Outcome Measures of Constipation in Postnata NCT06877871	Riphah International University	N/A
Completed	Effect of Transcutaneous Electrical Stimulation on Constipation NCT06198244	Riphah International University	N/A
Completed	A Novel Iron Supplement for Athletes: Phase I NCT06285851	University of Calgary	N/A
Completed	Comparison of the Efficacy of Different Nerve Stimulation Methods in Individuals With Chronic Consipation NCT06073249	Istanbul Medipol University Hospital	N/A
Completed	A Clinical Trial to Evaluate the Effect of ConcenTrace Trace Mineral Drops on Gut Health NCT06122571	Trace Minerals	N/A
Recruiting	Fecobionics in Biofeedback Therapy in Dyssynergia Patients NCT05807321	The California Medical Innovations Institute, Inc.	N/A
Unknown	Investigation of Low Back Pain Level on Symptoms in Chronic Consipation NCT06073262	Istanbul Medipol University Hospital	—
Completed	Fecal Microbiota Transplantation Via Oral Capsule for Treating Refractory Constipation in Parkinson's Disease NCT07038226	Kyung Hee University Hospital	N/A
Unknown	Clinical Study of Resistant Starch in Improving Constipation NCT06292949	Huaping Xie	N/A
Completed	Effect of L. Paracasei Strain Shirota on Constipation in Healthy US Adults NCT06014008	Yakult U.S.A. Inc.	N/A
Unknown	Study Intestinal Complaints During Chemotherapy. NCT05906186	Spaarne Gasthuis	—
Completed	Comparative Research Between Swenson and Soave Operations for Pediatric Patients Who Have Hirschsprung Disease NCT07410286	Ahmed Aouf	N/A
Withdrawn	Misoprostol for Bloating and Distension NCT04768010	Montefiore Medical Center	EARLY_Phase 1
Recruiting	Washed Microbiota Transplantation for Chronic Constipation in Adults NCT06106685	The Second Hospital of Nanjing Medical University	Phase 1 / Phase 2
Unknown	Colon Transit Study for Chronic Constipation Assessment and Therapy by Biofeedback With and Without TENS NCT05946967	Sanjay Gandhi Postgraduate Institute of Medical Sciences	N/A
Recruiting	Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flus NCT05821309	Indiana University	Phase 4
Recruiting	Preop Laxatives in Robotic Urologic Surgery NCT05805436	Chad R. Tracy	Phase 4
Completed	Telerehabilitation-based Exercise Training in Constipated Patients NCT05899062	Pamukkale University	N/A
Completed	The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes NCT05823259	University of Miami	N/A
Completed	Determining the Effect of Breathing Exercise Applied to Children Aged 6-12 Before Enema on Anxiety, Fear and P NCT05508022	KTO Karatay University	N/A
Completed	Effect of Therapeutic Touch on Functional Constipation in Infants and Young Children NCT06353841	Burdur Mehmet Akif Ersoy University	N/A
Completed	Traveler's Constipation NCT06155929	Herlev Hospital	N/A
Completed	Efficacy and Tolerability of ABB I5 Prebiotic and ABB C22 Postbiotics for the Management of Constipation and G NCT06738433	AB Biotek	EARLY_Phase 1
Active Not Recruiting	Treatment of Fecal Incontinence and Chronic Constipation With Low-volume Irrigation NCT05773742	Aarhus University Hospital	N/A
Completed	Efficacy of Different Nerve Stimulation Methods in Individuals With Chronic Constipation NCT05833191	Istanbul Medipol University Hospital	N/A
Active Not Recruiting	Investigating the Correlation Between Functional Constipation and Sacroiliac Joint Disorders NCT07344571	Middle East University	—
Unknown	Acupressure for Constipation in the Elderly NCT05805787	University of Yalova	N/A
Completed	Abdominal Massage With TENS on Parasacral Versus Sacral Area on Symptom,Severity & QOL in Chronic Constipation NCT06303011	Riphah International University	N/A
Unknown	Mixed Natural Prebiotic-Fibers Impact on Stool Frequency and Fecal Microbiota in Constipated Thai Adults NCT06274242	Mahidol University	N/A
Unknown	Investigating the Effects of Iron on the Gastrointestinal Tract NCT04253652	The Functional Gut Clinic	—
Enrolling By Invitation	Effect of Agave Inulin on Constipation and Quality of Life in Peritoneal Dialysis Patients. NCT06738550	NIN Institute	N/A
Completed	Effects of Psyllium on Constipation in Schizo-phrenic: A Randomized Controlled Crossover Trial NCT05528146	Hungkuang University	N/A
Active Not Recruiting	Efficacy of Combined Interferential Therapy and Electronic Cupping Therapy for Chronic Constipation Management NCT06611852	Middle East University	N/A
Completed	The Effects Of Probiotics On Stress Among Healthy Adults From Umm Al-Qura University At Makkah NCT06464484	Umm Al-Qura University	N/A
Recruiting	Usefulness of High Resolution Manometry in Constipation NCT04623359	University Hospital, Rouen	N/A
Unknown	Deep Needling at Zhongliao Point to Stimulate the Sacral Nerve for the Treatment of Slow Transit Constipation NCT06156995	Guoliang Wu	N/A
Completed	Care Package for Postoperative Constipation NCT06399133	Kubra KAYA	N/A
Completed	Effect of Probiotics on Constipation and Weight in CP NCT07393256	Ordu University	N/A
Unknown	The Effect of Abdominal Massage Applied After Surgery NCT05750186	Istanbul University	N/A
Completed	The Efficacy of Auricular Acupressure on Improving Constipation Among Residents in Community Rehabilitation Ce NCT05517460	Taipei Medical University	N/A
Unknown	Risk Factors for Bowel Dysfunction at Preschool and Early Childhood Age in Children With Hirschsprung Disease NCT05655845	Weibing Tang	—
Recruiting	Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth NCT05530681	Universitaire Ziekenhuizen KU Leuven	N/A
Completed	The Influence of Tramadol on Opioid-induced Bowel Dysfunction NCT06385561	Asbjørn Mohr Drewes	Phase 2
Recruiting	Pyridostigmine for the Treatment of Constipation in Parkinson Disease NCT05603715	University of Vermont Medical Center	Phase 2
Unknown	Effect of Bilateral Transcutaneous Tibial Nerve Stimulation on Postpartum Constipation NCT05455853	Cairo University	N/A
Unknown	The Long Term Outcomes After Pull-through of Long Segment Hirschsprung Disease NCT05461924	Weibing Tang	—
Unknown	Comparison of the Effects of Abdominal Massage and Kinesio Taping in Women With Chronic Constipation NCT05330728	Ankara Yildirim Beyazıt University	N/A
Completed	Abdominal Massage for People With Learning Disabilities and Constipation NCT05490654	Glasgow Caledonian University	N/A
Completed	GI Symptoms in Infants Fed Goat Milk-based Infant Formula NCT06755424	Ausnutria Hyproca B.V.	—
Completed	Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: PEGASIS Trial NCT05341180	All India Institute of Medical Sciences, Bhubaneswar	Phase 2 / Phase 3
Withdrawn	The Impact of Aerobic Interval and Inspiratory Muscle Training On Patient Reported Outcome Scores In Individua NCT05321953	University of Miami	N/A
Completed	Lactobacillus Casei Strain Shirota Fermented Milk for Alleviating Hard Stools in Vietnam NCT05982743	Yakult Honsha Co., LTD	N/A
Unknown	Mesenteric Sparing Surgery in Laparoscopic Colorectal Resection for Endometriosis NCT03565848	Università degli Studi dell'Insubria	—
Unknown	Laxative Properties of Microencapsulated Lipid (Constipation Study) NCT05324241	University College Dublin	N/A
Withdrawn	Do Probiotics Improve Recovery From Acute Constipation in Kids? NCT05734833	Connecticut Children's Medical Center	N/A
Completed	Transdermal Administration by a Novel Wireless Iontophoresis Device NCT06351852	James J. Peters Veterans Affairs Medical Center	EARLY_Phase 1
Completed	Effect of Abdominal Massage on Palliative Care Patients NCT05580679	Bartın Unıversity	N/A
Completed	Auricular Acupressure Relieves Constipation for Patients With Heart Failure in Hospital NCT05988502	Far Eastern Memorial Hospital	N/A
Completed	Effect of Chewing Gum and WeChat Enhanced Instructions on the Bowel Preparation Quality in Patients With Const NCT05447403	General Hospital of Shenyang Military Region	N/A
Unknown	Effectiveness of Partially Hydrolyzed Guar Gum in Improving Fecal Characteristics in Long Term Care Facility R NCT05037565	The University of Hong Kong	N/A
Active Not Recruiting	A Study to Assess Maternal and Fetal Outcomes After Taking Prucalopride During Pregnancy NCT04961840	Takeda	—
Unknown	Evaluate the Efficacy and Safety of Goofice® (Elobixibat) in Patients With Chronic Constipation NCT05895877	Synmosa Biopharma Corp.	Phase 3
Completed	The Effect of Inulin in Irritable Bowel Syndrome NCT06610188	Mardin Artuklu University	N/A
Completed	Yannianjiuzhuan Method and Reverse Breathing Training to Improve Constipation in Elderly Patients With Coronar NCT06401460	Junfang Miao	N/A
Unknown	A Study of Lubiprostone to Treat Constipation NCT04861233	Jeil Pharmaceutical Co., Ltd.	—
Terminated	A Study of Prucalopride For Functional Constipation in Children and Teenagers NCT04759833	Takeda	Phase 3
Withdrawn	Magnetic Resonance Imaging in Paediatric Constipation (MAGIC2) NCT05082129	Nottingham University Hospitals NHS Trust	N/A
Completed	Bacillus Coagulans Effect on Gastrointestinal Function in Healthy Adults. NCT06644001	Kerry Group P.L.C	N/A
Completed	Optimization of Transcutaneous Electrical Acustimulation (TEA) Modalities for Treatment of IBS-C NCT04953728	University of Michigan	N/A
Completed	A Probiotic Blend Reduces Gastrointestinal Symptoms and Positively Impacts Microbiota Modulation in a Randomiz NCT05614726	The Center for Applied Health Sciences, LLC	N/A
Completed	Polydextrose for Patients With Chronic Kidney Disease NCT05336305	Universidade Federal Fluminense	N/A
Completed	Nutrition to Relieve IBS Constipation NCT04798417	Wageningen University and Research	N/A
Completed	The Effects of Enzyme-rich Malt Extract on Chronic Constipation NCT04873466	The Functional Gut Clinic	N/A
Completed	Effects of Exercise Training on Pelvic Floor Symptoms and Function in Adults With Constipation NCT04661202	National Cheng Kung University	N/A
Active Not Recruiting	Neostigmine and Glycopyrrolate by Iontophoresis NCT06351995	James J. Peters Veterans Affairs Medical Center	Phase 3
Completed	Reflexology Socks and Opioid-induced Constipation NCT05314335	Muğla Sıtkı Koçman University	N/A
Completed	Open Label Tolerability Study of ISOThrive Prebiotic Nectar (MIMO) in Subjects With Constipation NCT04677634	ISOThrive Inc.	N/A
Completed	A Caregiver-mediated Health Educational Intervention to Improve Constipation Status of Primary School Children NCT04590846	Asia University	N/A
Unknown	Trancutaneous Abdominal Stimulation on Bowel Function. NCT04627168	Amol Soin, M.D., MBA	N/A
Completed	MRI Assessment of Mode of Action of Bisacodyl, Multiple Doses NCT04129788	University of Nottingham	Phase 4
Unknown	Effects of an Apple Derived Fibre Supplement on Constipation NCT04625881	University of Chile	Phase 3
Completed	Implementation of a Minor Ailment Service in Community Pharmacy Practice NCT05247333	Universidad de Granada	N/A
Completed	MRI Assessment of Mode of Action of Bisacodyl, Single Dose NCT04132661	University of Nottingham	Phase 4
Unknown	Effects of Synbiotics Supplementation on the Uremic Toxin Indoxyl Sulfate Level and Constipation in End-stage NCT04527640	Indonesia University	N/A
Completed	The Effect of Acupressure in Improving Constipation Among Inpatients in Neurology Departments NCT05612646	Taichung Veterans General Hospital	N/A
Unknown	Assessment and Validation of Electronic Gas and Bloating Diary NCT04684849	Augusta University	—
Unknown	Resection Location of Rectum in Laparoscopic Surgery for Slow Transit Constipation NCT04525248	Shanghai Minimally Invasive Surgery Center	N/A
Completed	Improving Constipation by Stimulating Fiber Intake Using Personalized Dietary Advice NCT04457791	Wageningen University	N/A
Completed	Effects of Prebiotic or Probiotic Supplements on Symptoms of Functional Constipation NCT04667884	Xi'an Jiaotong University	N/A
Completed	Tolerability and Functional Assessment of a Novel Children's Synbiotic NCT04534036	Seed Health	N/A
Terminated	Orally Administered ENT-01 for Parkinson's Disease-Related Constipation Follow-on Safety "Roll-over" Study (Ro NCT04483479	Enterin Inc.	Phase 2
Completed	Point-of-care Anorectal Testing to Predict Outcomes With Biofeedback Therapy: Clinical Trial NCT04159350	Dartmouth-Hitchcock Medical Center	N/A
Completed	Evaluation of Acacia Gum on Microbiome and Bowel Function in Participants With Chronic Constipation NCT04382456	Alpinia Laudanum GmbH	N/A
Completed	Association of Constipation Inflammatory and Microbial Translocation Markers NCT04307121	Tungs' Taichung Metroharbour Hospital	—
Completed	Constipation, Gut Microbiome, and Microbial-derived Uremic Toxins From the Gut Microbiota in HD Patients NCT04309019	Tungs' Taichung Metroharbour Hospital	—
Completed	Pharmacokinetics of Neostigmine and Glycopyrrolate NCT04027972	James J. Peters Veterans Affairs Medical Center	EARLY_Phase 1
Completed	Randomized Placebo-controlled Study of L. Reuteri NCIMB 30351 in GI Functional Disorders and Food Allergy in N NCT04262648	NovoNatum Ltd	N/A
Withdrawn	A Pilot Study to Explore the Role of Gut Flora in Chronic Constipation NCT04148248	ProgenaBiome	—
Unknown	Effect of Laser Acupuncture on Constipation in Patients With Advanced Cancer NCT04318808	Chang Gung Memorial Hospital	N/A
Completed	Post-Operative Constipation Following Total Knee Arthroplasty NCT04380090	The Cleveland Clinic	Phase 2
Enrolling By Invitation	Influence of Body Position on the Defecation Model During Anorectal Manometry. NCT06924957	Medical University of Warsaw	—
Completed	Posterior Tibial Nerve Stimulation for Children With Pelvic Floor Dyssynergia NCT06528470	Nationwide Children's Hospital	N/A
Completed	To Explore the Efficacy and Safety of Surgical Treatment for Constipation, as Well as the Changes of Postopera NCT05983926	Shanghai 10th People's Hospital	N/A
Unknown	Evaluation of the Impact of Transit Troubles in Patients Undergoing Peritoneal Dialysis NCT04102527	Centre Hospitalier de Vichy	—
Completed	Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy NCT04197869	Northwell Health	Phase 4
Active Not Recruiting	Comparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung's Disease NCT02234219	Tongji Hospital	N/A
Active Not Recruiting	MTT for Children With ASD Who Have Gastrointestinal Disorders NCT04182633	Arizona State University	Phase 2
Completed	Diarrhea and Stipsis in Critically Ill Patients (NUTRITI) NCT05473546	Azienda Sanitaria-Universitaria Integrata di Udine	—
Completed	Effect of 6 Weeks of Whole-body Vibration in Treatment of Postnatal Constipation NCT05286476	Cairo University	N/A
Completed	Bowel Function After Minimally Invasive Hysterectomy NCT04263896	University of Chicago	Phase 4
Completed	Constipation Bundle/Protocol and the Effect of Adherence in the Incidence of Constipation in Critically Ill Pa NCT04462211	University of Chile	N/A
Recruiting	Safety and Efficacy of Fecal Microbiota Transplantation NCT04014413	Chinese University of Hong Kong	N/A
Suspended	A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease NCT04031469	ProgenaBiome	—
Unknown	Prebiotic Fructans Effect on 1-3 Years Constipated Children's Bowel Habits NCT03941925	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	N/A
Unknown	Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation NCT03981510	University of Aarhus	N/A
Completed	Symptoms and Treatment Assessment of Ano-Rectal Disorders in Multiple Sclerosis Patients : STAR-Q NCT04996186	Pierre and Marie Curie University	—
Unknown	LAPEC for the Treatment of Severe Constipation NCT03909204	University Hospital Trnava	N/A
Unknown	Effect of Probiotic on Constipation in Patients With Parkinson's Disease NCT04293159	University of Salerno	N/A
Completed	Effect of Preoperative Fiber on Postoperative Bowel Function NCT04882995	University of Massachusetts, Worcester	N/A
Completed	PTNS and PFR in the Treatment of Childhood Constipation NCT05059756	Shengjing Hospital	N/A
Completed	Pelvic Floor and Sexual Dysfunction in Women With Sjogren's Syndrome NCT04415710	Akdeniz University	—
Completed	Effectiveness of Electromagnetic Field Therapy in Chronic Constipation NCT06578442	Medipol University	N/A
Recruiting	Understanding Mechanisms of Normal and Disordered Defecation NCT03842007	Mayo Clinic	N/A
Completed	Orally Administered ENT-01 for Parkinson's Disease-Related Constipation (KARMET) NCT03781791	Enterin Inc.	Phase 2
Completed	The Effects of Abdominal Massage on Functional (Primary) Chronic Constipation NCT03764995	Hacettepe University	N/A
Unknown	Electronic Mobile Phone App Stool Diary NCT04644133	Augusta University	—
Completed	The Incidence, Risk Factors, and Effects of Constipation in Critical Patients NCT05683743	Abant Izzet Baysal University	—
Completed	Probiotics-prebiotic Fiber Therapy in Parkinson's Disease Patients With Constipation NCT04451096	National University of Malaysia	Phase 3
Completed	Educational Intervention for Management of Constipation NCT04501263	University of Ulster	—
Completed	Probiotics in Elderly Patients With Medical Conditions NCT04035616	Universiti Kebangsaan Malaysia Medical Centre	N/A
Completed	Pelvic Floor Dysfunction and Its Influence on Body Image and Sexual Function NCT03591393	Universitaire Ziekenhuizen KU Leuven	N/A
Completed	Effects of Paediatric Tuina (Massage) on Constipation and Related Symptoms Among the Pre-school Aged Children NCT03751267	The University of Hong Kong	N/A
Completed	S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis NCT03499808	SWOG Cancer Research Network	Phase 2
Completed	Efficacy of Psychological Therapies in Patients With Functional Bowel Disorders NCT04060121	Indiana University	—
Completed	A Study of the Effect of Bran, Psyllium and Nopal on Intestinal Water Content Using Magnetic Resonance Imaging NCT03263065	University of Nottingham	N/A
Completed	Magnetic Resonance Imaging in Paediatric Constipation NCT03564249	Nottingham University Hospitals NHS Trust	N/A
Completed	CYPHP Evelina London Evaluation NCT03461848	Guy's and St Thomas' NHS Foundation Trust	N/A
Completed	Nutrition and Constipation at Inguinal Hernia Patients NCT03937739	Istanbul University	—
Unknown	3D High Resolution Manometry and Balloon Expulsion Test in Diagnosis of Dyssynergic Defecation in Children NCT02812836	Medical University of Warsaw	N/A
Unknown	Comparison of Anorectal Manometry and 3D Manometry in Diagnosis of Functional Disorders in Children NCT02812823	Medical University of Warsaw	N/A
Completed	Effectiveness and Safety of Sacral Neuromodulation in Patients With Idiopathic Slow-transit Constipation NCT02961465	Maastricht University Medical Center	—
Completed	Use of a Prokinetic Agent as an Adjunct to Thrice Weekly Bowel Care After SCI NCT04671030	James J. Peters Veterans Affairs Medical Center	Phase 1
Completed	Aromatherapy Massage Applied on Constipation NCT04513093	Ayşe Aydınlı	N/A
Completed	MOWOOT Device to Treat Constipation in Adults NCT04262752	usMIMA S.L.	N/A
Completed	Oral Administration of Polyethylene Glycol (PEG) for 6 Months in Chronically Constipated Autistic Children NCT05025553	University of Messina	N/A
Completed	Effectiveness of Squatting Position on Constipation Severity and Defecation Problems NCT05287789	Meltem Kaya	N/A
Terminated	Prunes for Gastrointestinal Function After Gynecologic Surgery NCT03523715	University of Southern California	Phase 4
Completed	A Pilot Study to Assess the Efficacy and Safety of Various Vibrating Capsule Modes NCT03329027	Vibrant Ltd.	N/A
Unknown	Naloxegol and Opioid-induced Constipation NCT03316859	TriHealth Inc.	Phase 2 / Phase 3
Completed	Parkinson's Disease and Digestive Health NCT04032262	Augusta University	N/A
Completed	Studies in Patients With Defecatory Disorders NCT03317938	Giome	N/A
Completed	Peritoneal Dialysis Pilot Study: Evaluating Polyethylene Glycol (PEG) for Constipation NCT03148002	Nova Scotia Health Authority	Phase 4
Completed	Effect of Kiwifruit on Gastrointestinal Fluid Distribution and Transit in Healthy Volunteers NCT03303417	University of Nottingham	N/A
Completed	Evaluation of Safety and Tolerability of ENT-01 for the Treatment of Parkinson's Disease Related Constipation NCT03047629	Enterin Inc.	Phase 1 / Phase 2
Completed	Efficacy of Chinese Herbal Medicine Xiaojidaozhi Decoction in the Treatment of Childhood Constipation NCT03186079	Shengjing Hospital	EARLY_Phase 1
Withdrawn	The Effect of Naloxegol on Refractory Constipation in the Intensive Care Unit NCT02705378	Massachusetts General Hospital	Phase 3
Completed	Fecal Calprotectin Collection Protocol NCT03143517	DiaSorin Inc.	—
Completed	Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes NCT02530216	Cedars-Sinai Medical Center	N/A
Unknown	Improving Bowel Habits of Elderly With Probiotics and Non-probiotics NCT02949882	Athena Institute, Netherlands	Phase 4
Completed	Investigation of the Absorption, Metabolism, and Excretion and the Absolute Bioavailability of YH12852 NCT03381703	Seoul National University Hospital	Phase 1
Completed	The Effect of CSP01 on Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation NCT03054506	Massachusetts General Hospital	N/A
Completed	Effect of L. Reuteri on Bowel Movements in Children (BIOWELL Study) NCT03030664	Centre Hospitalier Intercommunal Creteil	N/A
Completed	Dietary Supplementation Effects on Bowel Movement Frequency and Intestinal Biological Markers in Seniors Prese NCT04304170	CEN Biotech	N/A
Completed	Effectiveness and Cost-effectiveness of Sacral Neuromodulation in Patients With Idiopathic Slow-transit Consti NCT02961582	Maastricht University Medical Center	N/A
Completed	A Study to Assess the Efficacy and Safety of the Vibrant Capsule Administered 5 Times Per Week NCT03031301	Vibrant Ltd.	N/A
Terminated	Hypnosis for Children Undergoing Anorectal Manometry NCT04471857	Nationwide Children's Hospital	N/A
Unknown	Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery NCT02958566	University of Illinois College of Medicine at Peoria	Phase 4
Terminated	Naloxegol for the Prevention of Constipation in Postoperative Spinal Surgery Patients NCT02946580	Massachusetts General Hospital	Phase 4
Terminated	Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids NCT02977286	Tufts Medical Center	Phase 4
Completed	Comparison of Taste and Palatability in Fiber Supplements NCT02867917	Amsterdam UMC, location VUmc	N/A
Completed	Clinical Trial on Palliative Cancer Patients With Constipation NCT02795390	Hong Kong Baptist University	Phase 2
Withdrawn	Ease of Use, Tolerability, Efficacy and Safety of the Vibrant Capsule Administered in the Home Environment NCT02895516	Vibrant Ltd.	Phase 2
Completed	Nasogastric Tube Securement Comparison Study NCT03202576	University of Colorado, Denver	N/A
Terminated	Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipatio NCT02839889	Hospice of Henderson County, Inc.	Phase 4
Active Not Recruiting	Use of a Squatting Assist Device in Patients With Constipation NCT02877394	Mayo Clinic	Phase 2
Completed	The Efficacy of Mutaflor(E. Coli Nissle 1917, Mutaflor®) for Chronic Constipation:Multicenter Study NCT02726295	Keimyung University Dongsan Medical Center	Phase 4
Completed	ISE to Support Constipation Management NCT02977858	Children's Hospital Medical Center, Cincinnati	—
Terminated	Tolerability, Safety and Efficacy of a New Frequency of Vibrant Capsule Administration NCT02829047	Vibrant Ltd.	N/A
Unknown	Risk Factors for Inadequate Bowel Preparation in Patients With Chronic Constipation NCT02842411	Air Force Military Medical University, China	—
Completed	Effects of Probiotic on Modulation of the Intestinal Microbiota in Constipated Patients NCT03103958	Farmoquimica S.A.	N/A
Completed	Contribution of Percutaneous Endoscopic Caecostomie in the Management of Severe Constipation Refractory to Med NCT02566746	Nantes University Hospital	N/A
Completed	Impact of a Synbiotic Containing Fructo-oligosaccharides and Bifidobacteria in Middle-aged Adults NCT04283266	Vesale Pharmaceutica	N/A
Completed	Treatment of Constipation in Functional Dyspepsia NCT02956187	Hospital Universitari Vall d'Hebron Research Institute	N/A
Completed	Trial of Alvimopan in Major Spine Surgery NCT02789111	University of Virginia	Phase 4
Terminated	Treating Anorectal Dysfunction in MS NCT02609607	David Levinthal	Phase 2
Completed	RQ-00000010 for Gastroparesis and Constipation in Parkinson's Disease NCT02838797	Virginia Commonwealth University	Phase 1
Completed	BLI400-302: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults NCT02819297	Braintree Laboratories	Phase 3
Completed	A Safety and Efficacy Evaluation of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation NCT02822508	Braintree Laboratories	Phase 2 / Phase 3
Completed	An Open Label Study of Chronic Use of BLI400 Laxative in Constipated Adults NCT02819310	Braintree Laboratories	Phase 3
Completed	Multidimensional Risk Factor Assessment in Constipation NCT02884167	Queen Mary University of London	—
Unknown	Colonic Motility in Constipation and Aging: A Study With a New 3D Transit System NCT02805959	University of Aarhus	—
Completed	Lubiprostone for Chronic Idiopathic Constipation Treatment NCT02729909	Takeda	Phase 3
Unknown	Defecation Postures for Functional Consumption NCT02772692	Air Force Military Medical University, China	N/A
Terminated	Naloxegol in Cancer Opioid-Induced Constipation NCT02745353	Joseph Ma	Phase 2
Completed	Long Term Efficacy of Sacral Nerve Modulation (SNM) in Patients With Constipation or Stool Incontinence NCT02836717	Cantonal Hospital of St. Gallen	—
Completed	Evaluation of the Beneficial Effects of a Probiotic Product in Healthy Adult Subjects. NCT03234452	Montefarmaco OTC SpA	N/A
Completed	Lubiprostone for the Treatment of Chronic Idiopathic Constipation NCT02651155	Takeda	Phase 3
Withdrawn	Cognitive and Psychiatric Effects of Linaclotide on Patients With Constipation NCT03342287	McMaster University	—
Completed	Factors Affecting Dissatisfaction to Treatments in Patients With Chronic Constipation and IBS With Constipatio NCT02813616	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	—
Completed	A Pilot Study of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation NCT02820714	Braintree Laboratories	Phase 2
Unknown	Efficacy of Dicopeg Junior in Comparison With Lactulose for the Treatment of Functional Constipation in Childr NCT03177434	Children's Memorial Health Institute, Poland	Phase 4
Completed	A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adolescent Subjects NCT02665728	Braintree Laboratories	Phase 2
Withdrawn	Efficacy and Safety of Polyethylene Glycol 3350 (PEG 3350) for Relief of Constipation (MK-8114-005) NCT02292459	Bayer	Phase 3
Unknown	The Applying of Acupressure and Abdominal Massage to Improving Constipation in Stroke Patients. NCT03046563	Li-Li Chen	N/A
Completed	Colonic Motility in Constipation and Ageing NCT02575742	Queen Mary University of London	—
Completed	Effect of Probiotic on Constipation NCT03100851	China Agricultural University	Phase 3
Completed	Clinical Evaluation of the Effects of EpiCor on Digestive Comfort NCT03051399	ProDigest	N/A
Completed	Effect of Abdominal Massage on Bowel Evacuation After Cranial Surgery NCT04373772	Mersin University	N/A
Completed	Pre-biotics and Probiotics for Constipation in Parkinson's Disease NCT02459717	Emanuele Cereda	N/A
Completed	Gastrointestinal Transit Time in Patients With Severe Acquired Brain Injury NCT02428790	University of Aarhus	—
Withdrawn	Gastrointestinal Transit Time in Patients With Guillain-Barré Syndrome NCT02459808	University of Aarhus	—
Completed	Effect of a Fermented Milk Product With Probiotics Alone or in Combination With Fibers on Constipation Symptom NCT02461485	Danone Global Research & Innovation Center	N/A
Completed	Impact of Improving Gastrointestinal Symptoms on Autism Symptoms and Oxidative Stress NCT02442115	Children's Hospital Los Angeles	—
Unknown	Metagenome Analysis of Gut Microbiota in CC Patients NCT02395484	Jinling Hospital, China	—
Completed	Child Health Improvement Through Computer Automation of Constipation Management in Primary Care NCT02354820	William E. Bennett, Jr.	N/A
Completed	Relationship Between Constipation and Inguinal Hernia NCT02749682	Siverek Devlet Hastanesi	—
Unknown	Effect of Osteopathic Manipulative Medicine on Constipation in Parkinson's Disease NCT02344485	New York Institute of Technology	N/A
Completed	Gastrointestinal Dysfunction During Enteral Nutrition in Critically Ill Patients NCT04014816	Ayancık State Hospital	—
Completed	Transabdominal Electrical Stimulation for Constipation NCT02941471	St Mark's Hospital Foundation	Phase 1
Completed	Drink Milk Consumption Benefits With Culture Probiotic in the Treatment of Constipation NCT02446080	Centro Universitário Univates	N/A
Recruiting	Indiana University Gastrointestinal Motility Diagnosis Registry NCT04506593	Indiana University	—
Completed	The Effects of Connective Tissue Manipulation and Abdominal Massage in Patients With Chronic Constipation NCT02373488	Hacettepe University	N/A
Completed	Efficacy and Safety of Prucalopride in Combination With Polyethylene Glycol or Lactulose in Women With Chronic NCT02228616	Xian-Janssen Pharmaceutical Ltd.	Phase 4
Completed	The Efficacy of Individualised Homeopathic Treatment on Constipation NCT02411175	University of Johannesburg	Phase 2
Completed	Fibers and Gut Health NCT02234518	Société des Produits Nestlé (SPN)	N/A
Unknown	Anal Dilatation for Infants and Children With Constipation NCT02255747	Tongji Hospital	N/A

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