NCT06637397

Probiotics for Alleviating Functional Constipation in Adults

Assessing the Safety and Effectiveness of Weizmania Coagulant BC99 in Relieving Functional Constipation in Adults Based on Randomized, Double-Blind, Placebo-Controlled Trials

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Wecare Probiotics Co., Ltd. · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

To investigate the clinical effects of probiotics in relieving chronic constipation in adults, and evaluate the improvement of symptoms in patients with constipation as well as their impacts on gastrointestinal function, immunity, and gut microbiota.

Conditions

• Constipation

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotic	During the intervention, participants can consume BC99 daily and any adverse reactions were noted. Stool and serum samples were collected for analysis of 16S rRNA and serum inflammatory markers. Changes in intestinal flora and inflammatory factors before and after supplementation were assessed.
DIETARY_SUPPLEMENT	Placebo	During the intervention, participants can consume maltodextrin daily and any adverse reactions were noted. Stool and serum samples were collected for analysis of 16S rRNA and serum inflammatory markers. Changes in intestinal flora and inflammatory factors before and after supplementation were assessed.

Timeline

• Start date: 2024-05-30
• Primary completion: 2024-08-30
• Completion: 2024-11-15
• First posted: 2024-10-15
• Last updated: 2024-10-15

Locations

2 sites across 1 country: China