NCT06879587

Probiotics Alleviate Functional Constipation in Adults

Assessing the Safety and Effectiveness of Bacillus Coagulans BC99 in Relieving Functional Constipation in Adults Based on Randomized, Double-Blind, Placebo-Controlled Trials

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 84 (actual)
• Sponsor: Wecare Probiotics Co., Ltd. · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

To investigate the clinical effects of probiotics in relieving chronic constipation in adults, and evaluate the improvement of symptoms in patients with constipation as well as their impacts on gastrointestinal function, immunity, and gut microbiota.

Conditions

• Constipation

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotic	During the intervention, participants could take BC99 daily and record any adverse reactions. Participants filled out questionnaires and collected stool and serum samples, which were used to detect and analyze the improvement of participants' constipation function.
DIETARY_SUPPLEMENT	Placebo	During the intervention, participants could take maltodextrin daily and record any adverse reactions. Participants filled out questionnaires and collected stool and serum samples, which were used to detect and analyze the improvement of participants' constipation function.

Timeline

• Start date: 2024-09-08
• Primary completion: 2024-10-07
• Completion: 2024-12-17
• First posted: 2025-03-17
• Last updated: 2025-03-17

Locations

1 site across 1 country: China