NCT02395484

Metagenome Analysis of Gut Microbiota in CC Patients

Species and Metagenome Analysis of Gut Microbiota in Chronic Constipation Patients

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Jinling Hospital, China · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Constipation is a heterogeneous and multifactorial disease, influenced by a number of different genetic and environmental factors. By applying the standard two-stage GWAS strategy to design and carry out a metagenome-wide association study (MGWAS) to find the relationship between gut microbiota and constipation, to identify disease-associated metagenomic markers.

Detailed description

This study is a two-stage case-control metagenome-wide association study (MGWAS) based on deep next-generation shotgun sequencing of DNA extracted from the stool samples from a total of 50 Chinese constipation patients and healthy controls.

Conditions

• Constipation

Timeline

• Start date: 2015-03-01
• Primary completion: 2016-03-01
• Completion: 2016-06-01
• First posted: 2015-03-23
• Last updated: 2015-05-04

Locations

1 site across 1 country: China