Trials / Completed
CompletedNCT06123195
Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial
Clinical, Biochemical, and Microbiological Effects of Constipation Treatment in Patients With Chronic Kidney Disease: A Pilot Feasibility Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 14 (actual)
- Sponsor
- University of Tennessee · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Constipation is one of the most prevalent gastrointestinal disorders in patients with chronic kidney disease (CKD) and has been associated with their adverse kidney and cardiovascular outcomes; however, little is known about the effects of constipation treatment on clinical outcomes nor on outcome-related biochemical and microbiological parameters in patients with CKD. The investigators aim to test the feasibility of delivering an intervention with constipation treatment and determine its effects on changes in clinical, biochemical, and microbiological parameters in patients with CKD and constipation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Constipation treatment | Lactulose 15 mL (10 g) will be taken orally once daily (in the evening), which can be titrated at 1-week intervals in 15 mL (10 g) increments or decrements up to 60 mL (40 g) as a total daily dose. |
Timeline
- Start date
- 2024-02-01
- Primary completion
- 2025-11-17
- Completion
- 2025-11-17
- First posted
- 2023-11-08
- Last updated
- 2025-12-04
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT06123195. Inclusion in this directory is not an endorsement.