NCT07083596

Efficacy of LcS-Fermented Milk on Constipation-Related Symptoms in Filipino Adults

The Efficacy of Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota (LcS) on Relieving Constipation-Related Symptoms of Filipino Adults

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: University of Santo Tomas · Academic / Other
• Sex: All
• Age: 18 Years – 59 Years
• Healthy volunteers: Accepted

Summary

The primary purpose of this study is to investigate whether the consumption of a probiotic drink (with Lacticaseibacillus paracasei strain Shirota (LcS)) relieves constipation-related symptoms of Filipino adults, specifically its effect on stool consistency, frequency, and duration, and on gastrointestinal discomfort.

Detailed description

The goal of this clinical trial is to test if probiotic drink with LcS consumption can improve constipation-related symptoms. The main question\[s\] it aims to answer are: * Will a probiotic drink with LcS improve stool consistency after four weeks? * Will a probiotic drink with LcS improve stool frequency and duration after four weeks? * Will a probiotic drink with LcS improve gastrointestinal discomfort after four weeks? Participants will consume probiotic drink with LcS once a day for four weeks while maintaining their usual physical activity. Researchers will compare the control group and the probiotic group to see if there are differences in stool consistency, frequency and duration, and gastrointestinal symptoms.

Conditions

• Constipation
• Gastrointestinal Discomfort

Interventions

Type	Name	Description
OTHER	Experimental: Probiotic with LcS	Probiotic drink with LcS will be consumed once per day for four weeks
OTHER	Control	Brochure containing recommendations to improve constipation will be provided at end of study.

Timeline

• Start date: 2025-10-01
• Primary completion: 2026-04-01
• Completion: 2026-04-01
• First posted: 2025-07-24
• Last updated: 2025-10-06

Locations

1 site across 1 country: Philippines