| Not Yet Recruiting | PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study NCT05377320 | Medical College of Wisconsin | — |
| Not Yet Recruiting | Cardiotoxicity Assessment and Reduction Through Exercise in BREAST Cancer NCT07405385 | University of Castilla-La Mancha | N/A |
| Not Yet Recruiting | Artificial Intelligence for Reconstruction of Echocardiography Studies NCT07093918 | The Royal Wolverhampton Hospitals NHS Trust | — |
| Recruiting | Serial Cardiac Magnetic Resonance Imaging (CMR) With Contrast Agents and Biomarker Analysis for the Detection NCT07528586 | Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) | N/A |
| Active Not Recruiting | Impact of Exercise Intensity on Cardiac Health in Young Adult Survivors of Childhood Cancer: The PULSE Trial NCT07442578 | Dana-Farber Cancer Institute | N/A |
| Recruiting | In-Bedroom Renewed Air as Anti-inflammatory Adjuvant Therapy in Cancer Survivors NCT06778122 | University College, London | N/A |
| Recruiting | ML Score Prediction of Cardiotoxicity in Cancer Patients Receiving Anthracycline Chemotherapy or HER2-Targeted NCT07191730 | University Hospital, Caen | — |
| Enrolling By Invitation | Novel On-body Evaluation of Cardiac Health for Oncology NCT07158450 | Skribe Medical | — |
| Not Yet Recruiting | Cardiovascular Complications in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. NCT07157670 | Assistance Publique - Hôpitaux de Paris | — |
| Not Yet Recruiting | Optimizing Radiation Dose and Utilizing Wearable Devices to Reduce Arrhythmia Risk in Patients Undergoing Thor NCT06897189 | Yonsei University | — |
| Recruiting | Early Identification of Cardivascular Damage Induced by Chemotherapy and Antineoplastic Treatments in Pediatri NCT07382141 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | N/A |
| Enrolling By Invitation | Effects of Immune Checkpoint Inhibitors on Coronary Microvasculature NCT06332131 | Abramson Cancer Center at Penn Medicine | — |
| Recruiting | AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor NCT06699056 | Peerbridge Health, Inc | — |
| Not Yet Recruiting | Exercise for Ameliorating Chemotherapy Cardiotoxicity NCT06595316 | University of Hull | N/A |
| Completed | Dapagliflozin to Prevent Anthracycline-Induced Cardiotoxicity NCT06888505 | Hawler Medical University | Phase 2 |
| Recruiting | Breast cancEr, FITness and ExeRcise for Heart Health: The BE-FITTER Study NCT06595147 | University of Alberta | N/A |
| Recruiting | Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINST NCT05465031 | Silesian Centre for Heart Diseases | Phase 4 |
| Recruiting | Effects of Exercise Training in Survivors of Lymphoma NCT06270667 | Norwegian School of Sport Sciences | N/A |
| Recruiting | NT-proBNP to Assess Trastuzumab-induced Cardiotoxicity NCT06340516 | Vastra Gotaland Region | N/A |
| Recruiting | The STOP-MED CTRCD Trial NCT06183437 | Dinesh Thavendiranathan | Phase 4 |
| Enrolling By Invitation | Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors NCT06211413 | Abramson Cancer Center at Penn Medicine | — |
| Recruiting | The HIMALAYAS Trial and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Study: A M NCT05023785 | University Health Network, Toronto | N/A |
| Unknown | Effect of Spironolactone in the Prevention of Anthracycline-induced Cardiotoxicity (SPIROTOX) NCT06005259 | University of Sao Paulo | Phase 4 |
| Recruiting | Empagliflozin in the Prevention of Cardiotoxicity in Cancer Patients Undergoing Chemotherapy Based on Anthracy NCT05271162 | Maria Sklodowska-Curie National Research Institute of Oncology | Phase 3 |
| Recruiting | A Study of Blood Pressure Control During Cancer Treatment NCT06023576 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Recruiting | Cardioprotection on Chemotherapy-Induced Cardiotoxicity NCT06853951 | Ain Shams University | Phase 3 |
| Unknown | Safety of Withdrawal of Pharmacological Treatment for Recovered HER2 Targeted Therapy Related Cardiac Dysfunct NCT05880160 | University College, London | N/A |
| Recruiting | Dietary Restriction to Prevent Cardiotoxicity in Breast Cancer Patients NCT06622954 | Erasmus Medical Center | N/A |
| Completed | The Effects of Two Exercise Interventions on Breast Cancer Patients Undergoing Cardiotoxic Chemotherapies NCT05786014 | University of Virginia | N/A |
| Recruiting | Nicotinamide Riboside and Prevention of Cancer Therapy Related Cardiac Dysfunction in Breast Cancer Patients NCT05732051 | University Hospital, Akershus | Phase 2 |
| Terminated | Prediction of Delayed Toxic Cardiomyopathy in Children NCT05781672 | University Hospital, Montpellier | N/A |
| Unknown | Risk Analysis of Cardiotoxic Medication Use Due to Sodium Arsenite Chloride Injection NCT06060132 | Qianfoshan Hospital | — |
| Recruiting | Understanding CARdiac Events in Breast Cancer NCT05921279 | National University of Ireland, Galway, Ireland | — |
| Recruiting | Clinical and Diagnostic Significance of Endothelial Dysfunction and Myocardial Contractility in Patients With NCT05703126 | Samara State Medical University | N/A |
| Recruiting | Breast Cancer Long-term Outcomes on Cardiac Functioning: a Longitudinal Study NCT05851053 | University Medical Center Groningen | — |
| Active Not Recruiting | BIOMARKER and IMAGING CHARACTERISATION of INFLAMMATORY ATHEROMA in PATIENTS RECEIVING IMMUNOTHERAPY and ANGIOG NCT06597045 | NHS Greater Glasgow and Clyde | — |
| Recruiting | Global Cardio Oncology Registry NCT05598879 | The Cleveland Clinic | — |
| Completed | Cancer Therapy-Related Cardiac Dysfunction Associated With EGFR-TKIs in Advanced EGFR-mutant Non-small Cell Lu NCT07267247 | Taichung Veterans General Hospital | — |
| Unknown | Cancer Treatment Related Cardiovascular Toxicity: Comprehensive Myocardial and Vascular Phenotyping NCT06048458 | University College, London | — |
| Completed | The Harmonized Interventions to Maintain Health Via Appropriate Risk Factor Modification and Lifestyle Changes NCT04598646 | University Health Network, Toronto | N/A |
| Unknown | Identification of Novel Inflammation-related Biomarkers for Early Detection of Anthracycline-induced Cardiotox NCT05298072 | University Hospital, Essen | — |
| Terminated | Extensive CArdioVAscular Characterization and Follow-up of Patients Receiving Immune Checkpoint Inhibitors NCT05699915 | Algemeen Ziekenhuis Maria Middelares | N/A |
| Completed | Atherosclerosis in Chemotherapy-related Cardiotoxicity NCT05118178 | Maria Sklodowska-Curie National Research Institute of Oncology | — |
| Active Not Recruiting | Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Prostate Cancer NCT05096338 | Abramson Cancer Center at Penn Medicine | — |
| Active Not Recruiting | Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Breast Cancer NCT05078190 | Abramson Cancer Center at Penn Medicine | — |
| Unknown | Defining Robust Predictors of Chemotherapy Related Cardiotoxicity NCT05159479 | University College, London | — |
| Recruiting | Imaging Versus Cardiac Biomarker Monitored HER2 Directed Therapy in Patients With Breast Cancer NCT05406635 | Odense University Hospital | N/A |
| Unknown | Exercise Prescription Guided by Heart Rate Variability in Breast Cancer Patients NCT05040867 | GO fit Lab- Ingesport | N/A |
| Unknown | New Biomarkers in the Prediction of Chemotherapy-induced Cardiotoxicity. NCT05992337 | Cardiology Prague | — |
| Active Not Recruiting | Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxici NCT05036252 | Memorial Sloan Kettering Cancer Center | — |
| Unknown | Early Identification and Evaluation of Cyclophosphamide Cardiotoxicity NCT05150080 | Kai Mu | — |
| Unknown | Smart Home Care of Cloud Base ECG on the Cardiotoxicity Prevention on the Cancer Patients. NCT04885088 | Ju-Chi Liu | — |
| Unknown | Effect of Trimetazidine on Radiotherapy-induced Heart Damage. NCT04939857 | Peking University Third Hospital | Phase 2 / Phase 3 |
| Terminated | Validation of Quantitative Myocardial Tissue Characterization Through Non-gated CT NCT04880317 | IRCCS Policlinico S. Donato | N/A |
| Unknown | Strategy Therapy on Cancer Therapy-Related Cardiac Dysfunction NCT05892146 | National Cheng-Kung University Hospital | N/A |
| Terminated | Dyspnea and Cardiotoxicity in Multiple Myeloma Patients Who Receive Carfilzomib NCT04827563 | University of Chicago | — |
| Completed | Pilot Study of an NTproBNP Guided Strategy of Cardioprotection NCT04737265 | Abramson Cancer Center at Penn Medicine | Phase 1 / Phase 2 |
| Unknown | Investigating the Long-term Cardiac Sequelae of Trastuzumab Therapy NCT05019365 | University of Glasgow | — |
| Active Not Recruiting | Aerobic Exercise is Cardio-protective in Hemato-oncological Disease and New-onset Chemotherapy NCT04476576 | Lucía Florio | N/A |
| Completed | CAR T Cell Therapy Related Cardiovascular Outcomes NCT05130489 | University College London Hospitals | — |
| Unknown | Assessment of Myocardial Injury in Patients Treated With Immune Checkpoint Inhibitors NCT05349058 | Flinders University | — |
| Completed | Cardiotoxicity Monitoring With Single-lead Electrocardiogram NCT05676606 | I.M. Sechenov First Moscow State Medical University | N/A |
| Unknown | Can Flaxseed Prevent Broken Hearts in Women With Breast Cancer Study? NCT04632407 | St. Boniface Hospital | N/A |
| Unknown | Mazankowski Alberta Heart Institute (MAHI) EchoGo Discovery 1 Protocol NCT04877899 | Ultromics Ltd | — |
| Completed | Early Detection of Cardiotoxicity From Systemic and Radiation Therapy in Breast Cancer Patients NCT04790266 | Oncology Institute of Southern Switzerland | — |
| Active Not Recruiting | Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy NCT04305613 | Abramson Cancer Center at Penn Medicine | — |
| Completed | Effect of Anthracyclines and Cyclophosphamide on Cardiovascular Responses NCT04568161 | University of Sao Paulo General Hospital | N/A |
| Completed | Cardiotoxicity in Breast Cancer Patients Treated With Proton or Photon Radiotherapy: A RadComp Companion Study NCT04361240 | Abramson Cancer Center at Penn Medicine | — |
| Completed | Cardiac Effects From Radiation Therapy by MRI NCT04486573 | University of Colorado, Denver | N/A |
| Unknown | Effect of Genetic and Epigenetic Factors on the Clinical Response and Toxicity to Cisplatin Among Egyptian Non NCT05746598 | Ain Shams University | — |
| Unknown | Early Detection of Cardiac Damage With CMR in Women With Breast Cancer NCT04046315 | Radboud University Medical Center | — |
| Completed | Cardiotoxicity and Other Late Effects After Radiotherapy and Immuno-chemoTherapy in Non-Hodgkin lYmphoma NCT07041827 | The Netherlands Cancer Institute | — |
| Completed | Multimodal Assesment of Acute Cardiac Toxicity Induced by Thoracic Radiotherapy in Cancer Patients NCT04896242 | Pontificia Universidad Catolica de Chile | — |
| Unknown | Cardiotoxicity of Aluminum Phosphide Poisoning; Tropinin and CKmb as Early Biomarkers NCT04191265 | Assiut University | — |
| Unknown | Evaluation of Myocardial Injury After Anthracycline Chemotherapy in Osteosarcoma Patients Using CMR NCT04461223 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Recruiting | Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure NCT04262830 | Hari Narayan | — |
| Unknown | Effect of Angiotensin Converting Enzyme and Sacubitril Valsartan in Patients After Bone Marrow Transplantation NCT04092309 | University of Athens | N/A |
| Completed | Risk-Guided Cardioprotection With Carvedilol in Breast Cancer Patients Treated With Doxorubicin and/or Trastuz NCT04023110 | Abramson Cancer Center at Penn Medicine | Phase 1 |
| Recruiting | Cardiovascular Prevention Strategies in Elderly Patients With Cancer (CARTIER Clinical Trial) NCT03711110 | Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León | N/A |
| Completed | Cardiovascular Effects of CART Cell Therapy NCT04026737 | Abramson Cancer Center at Penn Medicine | — |
| Unknown | Strain vs. Left Ventricular Ejection Fraction-based Cardiotoxicity Prevention in Breast Cancer NCT04429633 | Samsung Medical Center | N/A |
| Completed | Cardiovascular Diagnostic in Assessment of Risk HDS and HCT in Patients With Haemoblasts. NCT05508087 | I.M. Sechenov First Moscow State Medical University | N/A |
| Unknown | Evaluation of Heart Function in Breast Cancer Patients Using Trastuzumab NCT04961307 | Peking University Third Hospital | — |
| Unknown | Observational Trial of Cardiotoxicity in Patients Undergoing Chemotherapy. NCT04055636 | Moscow State University of Medicine and Dentistry | — |
| Unknown | Vascular Cardiotoxicity of Ponatinib NCT03930394 | Oregon Health and Science University | — |
| Terminated | Cancer Adverse Effects PReventIon With Care & Exercise: the CAPRICE Study NCT03850171 | Insel Gruppe AG, University Hospital Bern | N/A |
| Active Not Recruiting | Exercise to Prevent AnthraCycline-based Cardio-Toxicity Study 2.0 (EXACT2) NCT03748550 | Nova Scotia Health Authority | N/A |
| Terminated | PROactive Evaluation of Function to Avoid CardioToxicity NCT03862131 | Washington University School of Medicine | Phase 2 |
| Unknown | Ivabradine to Prevent Anthracycline-induced Cardiotoxicity NCT03650205 | University of Sao Paulo | N/A |
| Unknown | Cardioprotective Effects of Nebivolol Versus Placebo in Patients Undergoing Chemotherapy With Anthracyclines NCT05728632 | Giulio Stefanini | Phase 3 |
| Completed | Cardiovascular Function in Acute Leukemia NCT03760237 | Abramson Cancer Center at Penn Medicine | — |
| Completed | Exercise-based Cardiac Rehabilitation for the Prevention of Breast Cancer Chemotherapy-induced Cardiotoxicity NCT03964142 | Hospital Clinico Universitario de Santiago | N/A |
| Unknown | Statins for the Primary Prevention of Heart Failure in Patients Receiving Anthracycline Pilot Study NCT03186404 | University Health Network, Toronto | Phase 2 |
| Recruiting | Study on Proton Radiotherapy of Thymic Malignancies NCT04822077 | Ass. Prof. Jan Nyman | N/A |
| Completed | Prevention of Chest Pain in Chemo-treated Cancer Patients NCT03486340 | Vejle Hospital | N/A |
| Completed | Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid Leukemia NCT03389724 | Children's Cancer Hospital Egypt 57357 | Phase 3 |
| Recruiting | S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk NCT03418961 | SWOG Cancer Research Network | Phase 3 |
| Completed | MyoStrain CMR for the Detection of Cardiotoxicity NCT03543228 | Myocardial Solutions | — |
| Completed | Remote Ischaemic Preconditioning in Childhood Cancer NCT03166813 | The University of Hong Kong | N/A |
| Unknown | The Safety Management of Cardiac Toxicity in Breast Cancer Patients Under Multidiscipline Therapy. NCT02942615 | Ruijin Hospital | N/A |
| Completed | The CAROLE (CArdiac Related Oncologic Late Effects) Study NCT03235427 | Northwell Health | — |
| Unknown | Novel Biomarkers and Echocardiography for Subclinical Cardiac Toxicity in Breast Cancer Patients Receiving Ant NCT03155802 | Stony Brook University | — |
| Unknown | Effect of Physical Training in Patients With Heart Failure Caused by Chemotherapy for Cancer Treatment NCT04047901 | University of Sao Paulo General Hospital | N/A |
| Completed | Optimising Screening for the Cardiotoxic Effects of Cancer Therapy NCT06817044 | Barts & The London NHS Trust | — |
| Completed | Cardiac Safety of Dihydroartemisinin-Piperaquine Amongst Pregnant Women in Tanzania NCT02909712 | London School of Hygiene and Tropical Medicine | Phase 2 |
| Completed | Cardiac Fibrosis and Risk Prediction in Cancer Treatment-Related Cardiotoxicity NCT02798679 | University of Minnesota | — |
| Terminated | STOP Heart Disease in Breast Cancer Survivors Trial NCT02674204 | Cedars-Sinai Medical Center | Phase 2 |
| Unknown | Effect of Remote Ischaemic Conditioning in Oncology Patients NCT02471885 | University College, London | N/A |
| Unknown | Cardiotoxicity Prevention in Breast Cancer Patients Treated With Anthracyclines and/or Trastuzumab NCT02236806 | Azienda Ospedaliero-Universitaria Careggi | Phase 3 |
| Completed | Role of Aerobic Exercise to Modulate Cardiotoxicity in Long Term Cancer Survivors Exposed to Anthracycline The NCT04036032 | Connecticut Children's Medical Center | — |
| Completed | Anthracycline Induced Cardiotoxicity - Early Detection by Combination of Diastolic Strain and T2-mapping NCT03940625 | Heinrich-Heine University, Duesseldorf | N/A |
| Unknown | Cardiotoxicity in the Elderly NCT03981588 | AORTICA Group | — |
| Terminated | Early Detection of Cardiac Toxicity in Childhood Cancer Survivors NCT03038997 | Niti Dham | — |
| Unknown | The Cardio-Oncology Breast Cancer Study NCT02571894 | Karolinska University Hospital | N/A |
| Unknown | Cardiotoxicity in Metastatic Her 2 Positive Patients Treated With Trastuzumab ,Pertuzumab and Taxanes NCT02101879 | Rambam Health Care Campus | — |
| Completed | Early Detection of Broken Hearts in Cancer Patients NCT02086695 | Mayo Clinic | — |
| Completed | Carvedilol Effect in Preventing Chemotherapy - Induced Cardiotoxicity NCT01724450 | University of Sao Paulo | Phase 3 |
| Completed | Usefulness of Myocardial Deformation Imaging for Trastuzumab-induced Cardiotoxicity NCT01665300 | Seoul National University Hospital | — |
| Completed | A Prospective Study of Acute Cardiovascular Effects of First-line Sunitinib in Metastatic Renal Cell Carcinoma NCT01014065 | AHS Cancer Control Alberta | — |
| Completed | Sunitinib and Atrial Trabeculae Contractility NCT01246778 | Radboud University Medical Center | — |
| Completed | Staccato Prochlorperazine Thorough QT/QTc NCT00543062 | Alexza Pharmaceuticals, Inc. | Phase 1 |
| Completed | Prevention of Chemotherapy-induced Cardiotoxicity in High-risk Patients NCT00292526 | European Institute of Oncology | Phase 4 |