Trials / Completed
CompletedNCT03486340
Prevention of Chest Pain in Chemo-treated Cancer Patients
Prevention of CArdioToxic-related CHest Pain in Cancer Patients Treated With 5-fluorouracil
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 218 (actual)
- Sponsor
- Vejle Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is a prospective, exploratory, randomised clinical trial. Patients with diagnosed cancer that are to be treated with 5-fluorouracil (5-FU) will be randomised into standard oncological treatment or a cardiological assessment prior to the 5-FU treatment. The investigators hypothesize that aggressive management of ischemic risk factors in asymptomatic patients will reduce the number of hospitalisations and investigations for acute coronary syndrome during and after 5-FU treatment and that patients with high coronary artery calcium scores are more likely to experience chest pain during the treatment with 5-FU.
Conditions
- Solid Carcinoma
- 5-Fluorouracil Toxicity
- Cardiotoxicity
- Chemotherapeutic Toxicity
- Acute Coronary Syndrome
- Coronary Artery Calcification
- Chest Pain
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Cardiologic assessment | Aggressive ischemic risk factor management |
Timeline
- Start date
- 2018-04-11
- Primary completion
- 2024-06-07
- Completion
- 2024-06-07
- First posted
- 2018-04-03
- Last updated
- 2024-07-08
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT03486340. Inclusion in this directory is not an endorsement.