| Not Yet Recruiting | Lithotripsy Versus Balloon Angioplasty for Optimal Treatment of CAlcified Lesions With and Without Optical Coh NCT07388030 | Shanghai Bluesail Boyuan Medical Technology Co., Ltd. | N/A |
| Not Yet Recruiting | Health Enhanced Artery Risk Tracking With Widespread Implementation and Screening Effort in ASCVD (HEARTWISE-A NCT07355894 | Stanford University | N/A |
| Not Yet Recruiting | Intravascular Imaging-Guided Intravascular Lithotripsy for Severe Coronary Calcified Lesions. NCT07444346 | The First Affiliated Hospital with Nanjing Medical University | — |
| Active Not Recruiting | ClinicAL outComes of IntraVascular Lithotripsy Combined With Conventional Lesion Preparation in Patients With NCT07340294 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | TECTONIC CAD IVL IDE Study NCT06885177 | Abbott Medical Devices | N/A |
| Not Yet Recruiting | A MAajor RAdiation-based PCI Study in STEMI and NSTEMI NCT06565793 | Centre Cardiologique du Nord | — |
| Active Not Recruiting | Notification of Incidental Coronary Artery Calcium in Patients With Atherosclerotic Cardiovascular Disease (NO NCT05858879 | Stanford University | N/A |
| Completed | Coronary Artery Calcification Assessed on PET Scanner (PET : Positron Emission Tomography) NCT06379295 | Centre Hospitalier Régional d'Orléans | — |
| Unknown | The AI-CAC Model for Subclinical Atherosclerosis Detection on Chest X-ray NCT06301009 | A.O.U. Città della Salute e della Scienza | N/A |
| Enrolling By Invitation | The Influence of Modifying Highly Calcified Coronary Lesions on Coronary Microcirculation NCT06507449 | Medical University of Silesia | N/A |
| Recruiting | A Novel Ferumoxytol-enhanced Cardiac Magnetic Resonance for the Detection of Calcified Coronary Arteries NCT07400406 | The First Affiliated Hospital with Nanjing Medical University | — |
| Active Not Recruiting | Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACT NCT06181240 | Bolt Medical | N/A |
| Completed | Picture of Incidental Calcium To Understand Risk Estimate (PICTURE) Trial NCT05588895 | Stanford University | N/A |
| Recruiting | High-intensity Statin and Ezetimibe Therapy for Asymptomatic Patients With Positive Coronary Calcium NCT05845424 | Samsung Medical Center | Phase 4 |
| Active Not Recruiting | Quebec Lung Cancer Screening PLUS Trial NCT05444062 | Nicole Ezer, MD, FRCPC, MPH | N/A |
| Unknown | Coronary Intravascular Lithotripsy System in Patients With Coronary Artery Calcification (VIGOUR) NCT05818098 | Shanghai MicroPort Rhythm MedTech Co., Ltd. | N/A |
| Recruiting | The Value of IVL Compared To OPN Non-Compliant Balloons for Treatment of RefractorY Coronary Lesions (VICTORY) NCT05346068 | Luzerner Kantonsspital | N/A |
| Active Not Recruiting | The InterVitaminK Trial - Effects of Vitamin K Supplementation on Cardiovascular, Metabolic, and Bone Health NCT05259046 | Bispebjerg Hospital | N/A |
| Completed | Comparison of Cardiovascular Risk Stratification in Young People With Type 1 Diabetes by Coronary Calcium Scor NCT05283538 | Poitiers University Hospital | N/A |
| Unknown | Neointimal Features in Patients With Restenosis of Calcified Lesions NCT05451368 | Shenyang Northern Hospital | — |
| Unknown | Shockwave Induced Attenuation of Calcified Plaques Quantified With OCT NCT05973994 | University of Rome Tor Vergata | — |
| Unknown | CAlcified Lesion Intervention Planning Steered by OCT. NCT05301218 | Institut Mutualiste Montsouris | N/A |
| Recruiting | COMPLEX Registry - a Prospective COhort Study to Describe the Management and Outcomes of Patients Presenting w NCT06075602 | Luzerner Kantonsspital | — |
| Recruiting | SIROOP Registry - A Prospective Registry Study to Evaluate the Outcomes of Coronary Artery Disease Patients Tr NCT04988685 | Luzerner Kantonsspital | — |
| Recruiting | Coronary Artery Calcification in Type 2 Diabetes Mellitus (USCAC Study) NCT04889053 | University of South China | — |
| Recruiting | ROVUS Asia Registry (Evaluate Safety and Effectiveness of Rotational Atherectomy and Intravascular Ultrasound NCT04742478 | National Heart Centre Singapore | — |
| Unknown | The Efficacy and Safety of a Novel Adjunctive Pacing Strategy During Rotational Atherectomy NCT05404204 | Vancouver Island Health Authority | — |
| Unknown | CCTA, CACS and ECG Stress Testing in Patients With Suspected CAD: Precision Phenotyping and Financial Evaluati NCT04424121 | Aristotle University Of Thessaloniki | N/A |
| Completed | IVL vs ELCA for Stent Underexpantsion (IVL-ELCA DRAGON) NCT06276114 | Medical University of Silesia | — |
| Unknown | Coronary Calcification Study - Intravascular Lithotripsy for Calcified Lesions NCT04428177 | University Hospital Ostrava | N/A |
| Unknown | Intravascular Balloon Lithotripsy in Left Main Stem Percutaneous Coronary Intervention NCT04319666 | St George's, University of London | N/A |
| Completed | Balloon Lithoplasty for Preparation of Severely Calcified Coronary Lesions NCT04253171 | Herlev and Gentofte Hospital | N/A |
| Completed | IVL for Stent Underexpantsion NCT05112250 | Medical University of Silesia | — |
| Completed | Toe-brachial Index and Coronary Calcification in Type 1 and 2 Diabetes NCT03920683 | Assistance Publique - Hôpitaux de Paris | — |
| Unknown | Melatonin on Coronary Artery Calcification NCT03966235 | Chinese PLA General Hospital | Phase 4 |
| Completed | Prevention of Chest Pain in Chemo-treated Cancer Patients NCT03486340 | Vejle Hospital | N/A |
| Completed | Melatonin and Coronary Artery Calcification NCT03967366 | Chinese PLA General Hospital | — |
| Completed | Personalization of CM Injection Protocols in Coronary Computed Tomographic Angiography NCT03292354 | Maastricht University Medical Center | N/A |
| Completed | Effect of SNF472 on Progression of Cardiovascular Calcification in End-Stage-Renal-Disease (ESRD) Patients on NCT02966028 | Sanifit Therapeutics S. A. | Phase 2 |
| Terminated | Screening for Coronary Artery Disease USing Primary Evaluation With Coronary CTA in Aviation Medicine (SUSPECT NCT05508893 | UMC Utrecht | N/A |
| Completed | Prevention of the Progression of Coronary Calcification With Use of Spironolactone in Peritoneal Dialysis Pati NCT03314493 | Professor Fernando Figueira Integral Medicine Institute | Phase 3 |
| Unknown | The Effects and Safety of Low Calcium Dialysis on Coronary Artery Calcification in Maintenance Hemodialysis Pa NCT02498457 | First Affiliated Hospital of Chongqing Medical University | N/A |
| Completed | 7 Year Follow-up Study of the DanRisk Population NCT02913144 | Odense University Hospital | — |
| Completed | MAP-Calcification: MicroRNAs as Potential Biomarkers for Coronary Artery Calcification NCT01992848 | University of Surrey | N/A |
| Completed | French CAC-HIV Cohort Study NCT05563116 | Franck Boccara | — |
| Unknown | Association Between Non-alcoholic Fatty Liver Disease (NAFLD) and Coronary Artery Calcification NCT01158066 | Ziv Hospital | N/A |
| Unknown | Vitamin K2 and Vessel Calcification in Chronic Kidney Disease Patients NCT01101698 | Medical University of Lodz | Phase 4 |
| Completed | Firefighter Aged Garlic Extract Investigation With CoQ10 as a Treatment for Heart Disease (FAITH) NCT00860847 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Phase 3 |
| Completed | A Study Comparing Skin Fluorescence to Coronary Artery Calcification NCT00895427 | VeraLight, Inc. | — |
| Completed | ADVANCE: Study to Evaluate Cinacalcet Plus Low Dose Vitamin D on Vascular Calcification in Subjects With Chron NCT00379899 | Amgen | Phase 4 |