NCT07400406

A Novel Ferumoxytol-enhanced Cardiac Magnetic Resonance for the Detection of Calcified Coronary Arteries

Diagnostic Performance of a Novel Ferumoxytol-enhanced Cardiac Magnetic Resonance for the Detection of Calcified Coronary Arteries: A Single-center Clinical Study.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: The First Affiliated Hospital with Nanjing Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This study is a single-center, prospective, controlled, diagnostic study. The study will be consecutive and is expected to enroll 100 patients with CCTA confirmed coronary calcified lesions. The purpose of this study was to compare the accuracy of novel Ferumoxytol-enhanced Cardiac Magnetic Resonance (Fe-CMR) and coronary CT angiography (CCTA) in detecting calcified coronary arteries, using coronary angiography (CAG) and optical coherence imaging (OCT) as gold standards.

Conditions

• Coronary Artery Calcification

Interventions

Type	Name	Description
DRUG	Superparamagnetic Iron Oxide Nanoparticles	Patients will receive a novel ferumoxytol-enhanced cardiac magnetic resonance imaging.

Timeline

• Start date: 2024-01-26
• Primary completion: 2027-08-31
• Completion: 2027-08-31
• First posted: 2026-02-10
• Last updated: 2026-02-10

Locations

1 site across 1 country: China