Trials / Terminated
TerminatedNCT03038997
Early Detection of Cardiac Toxicity in Childhood Cancer Survivors
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 42 (actual)
- Sponsor
- Niti Dham · Academic / Other
- Sex
- All
- Age
- 8 Years – 25 Years
- Healthy volunteers
- Not accepted
Summary
To evaluate cardiac MRI and/or serum biomarkers for detecting cardiac cardiac toxicity in children who received anthracycline based chemotherapy (ABC).
Detailed description
Cardiac toxicity is a significant potential complication for patients receiving anthracycline chemotherapy. Cells in the cardiovascular system have limited regenerative capability, making them susceptible to long term adverse effects from these chemotherapeutic agents. The ability to detect subclinical changes in cardiac function will allow clinicians to use proven treatments to prevent further progression in this vulnerable population. The current standard testing uses echocardiography, which is not as sensitive as cardiac MRI or serum biomarkers.
Conditions
Timeline
- Start date
- 2014-11-01
- Primary completion
- 2018-03-11
- Completion
- 2018-03-11
- First posted
- 2017-02-01
- Last updated
- 2018-12-04
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03038997. Inclusion in this directory is not an endorsement.