| Not Yet Recruiting | Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children Wi NCT07486167 | Charite University, Berlin, Germany | Phase 1 / Phase 2 |
| Not Yet Recruiting | Effect of Hypothermia on BIS and PSI Correlation During Cardiopulmonary Bypass NCT07508579 | Sakarya University | — |
| Recruiting | CompaRison of FEmorofemoral Bypass and Left-Heart ByPass Techniques in Open Thoracoabdominal AortIc Aneurysm R NCT07518251 | Beijing Anzhen Hospital | N/A |
| Not Yet Recruiting | Comparison of Milrinone and Epinephrine on TAPSE NCT07144267 | Mansoura University | N/A |
| Recruiting | GLS in Difficult CPB Weaning NCT07390903 | Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital | — |
| Recruiting | Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Childr NCT07193719 | Charite University, Berlin, Germany | Phase 1 / Phase 2 |
| Not Yet Recruiting | Remimazolam vs Midazolam to Reduce Delirium in Adults ≥65 Undergoing CPB Valve Surgery NCT07265128 | Yonsei University | Phase 4 |
| Completed | Effective Myocardial Protection Time of Del Nido Cardioplegia in Adult Cardiac Surgery NCT07249424 | Muhammet Talha Ceran, MD | — |
| Recruiting | Safety and Performance Evaluation of CPB Venous and Arterial Cannulas NCT07354841 | Eurosets S.r.l. | N/A |
| Not Yet Recruiting | Autologous Cold-stored Apheresis Platelets NCT07064954 | University Health Network, Toronto | Phase 2 / Phase 3 |
| Recruiting | Heart-Lung Machine: Impact of the Priming Solution on Acid-Base Balance, Electrolytes and Outcome on Patients NCT07267546 | Region Skane | N/A |
| Completed | Evaluation of Optic Nerve Sheath Diameter Changes During Cardiopulmonary Bypass in Open Heart Surgery NCT07253922 | Medipol University | — |
| Recruiting | Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass NCT06702553 | Xijing Hospital | Phase 3 |
| Recruiting | Prophylactic Methylprednisolone for Renal Protection in Cardiac Surgeries With Cardiopulmonary Bypass NCT06917859 | Ain Shams University | Phase 1 |
| Recruiting | Amobarbital and Cardiopulmonary Bypass NCT06757868 | Tongji Hospital | N/A |
| Enrolling By Invitation | Research on Circulation Management Strategy Based on Oxygen Metabolism Balance After CHD Surgery NCT06747546 | Children's Hospital of Fudan University | N/A |
| Completed | Effect of Low Tidal Volume Ventilation on Postoperative Delirium NCT06752421 | Nevsehir Public Hospital | N/A |
| Enrolling By Invitation | Protective Effect of Probacine Against Negative Gut Metabolism and Organ Dysfunction After Cardiovascular Surg NCT04444362 | Nanjing Medical University | N/A |
| Not Yet Recruiting | Protective Effect of RIPC Against Negative Inflammatory Response and Organ Dysfunction After Cardiovascular Su NCT06707350 | Nanjing Medical University | N/A |
| Recruiting | Ultrasound Guided Bilateral Pectoral Nerve Block Versus Bilateral Transverse Thoracic Plane Block In Pediatric NCT06984276 | Cairo University | N/A |
| Completed | Evaluation of TEG 6S PM® During Cardiopulmonary Bypass to Detect Postoperative Biological Coagulopathy NCT06230640 | University Hospital, Montpellier | — |
| Recruiting | Delayed Cold-Stored Platelets -PLTS-1 NCT06147531 | University Health Network, Toronto | Phase 2 |
| Not Yet Recruiting | Concomitant Tricuspid Repair in Patients With Left Heart Surgery NCT05595187 | Nanjing Medical University | N/A |
| Recruiting | Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients NCT06279793 | GCP-Service International West GmbH | Phase 2 |
| Recruiting | The Effect of ACT and Tranexamic Acid on Bleeding in Cardiac Surgery NCT06109155 | Taichung Veterans General Hospital | Phase 4 |
| Terminated | Heart Lung Machine Registry NCT06159517 | Maquet Cardiopulmonary GmbH | — |
| Completed | Oxygen Delivery During Cardiopulmonary Bypass And Inflammatory Reaction After Cardiac Surgery NCT06993467 | Azienda Ospedaliero, Universitaria Ospedali Riuniti | — |
| Active Not Recruiting | ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE NCT05746559 | Alexion Pharmaceuticals, Inc. | Phase 3 |
| Recruiting | Effect of Methylprednisolone on Systemic Inflammatory Response During Pediatric Congenital Open-Heart Surgery NCT05927233 | Aga Khan University | Phase 4 |
| Completed | Restrictive Transfusion StratEgy Adjusted by SvO2 During Cardiac Surgery NCT05740059 | University Hospital, Montpellier | N/A |
| Completed | Perioperative Nitric Oxide Prevents Acute Kidney Injury in Cardiac Surgery Patients With Chronic Kidney Diseas NCT05757557 | Tomsk National Research Medical Center of the Russian Academy of Sciences | Phase 1 / Phase 2 |
| Completed | Impact of Cardiopulmonary Bypass Flow on Cerebral Autoregulation NCT05681741 | Clinique de la Sauvegarde | N/A |
| Completed | Choroidal Changes During Cardiopulmonary Bypass NCT07034612 | Samsun University | — |
| Completed | Novel Venous Cannula Trial NCT07087639 | Eurosets S.r.l. | N/A |
| Unknown | Impact of Levosimendan Preconditioning on Critical Care and In-hospital Lengths of Stay After Cardiac Surgery NCT05685537 | Central Hospital, Nancy, France | — |
| Recruiting | Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB) NCT04296071 | Sophia Koutsogiannaki | — |
| Completed | The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy NCT05579964 | National Cardiovascular Center Harapan Kita Hospital Indonesia | Phase 2 / Phase 3 |
| Completed | Influence of Oxygenator Selection on Platelet Function and Rotational Thromboelastometry Following Cardiopulmo NCT05588011 | BRADEN DULONG | N/A |
| Completed | Influence of Preop Fibrinogen on Blood in Pediatric Cardiac Surgery NCT05525195 | Brugmann University Hospital | — |
| Completed | Bayesian Networks in Pediatric Cardiac Surgery NCT05537168 | Brugmann University Hospital | — |
| Completed | Impact of Chest Wall Mechanics on Lung and Cardiovascular Function During Delayed Sternal Closure NCT05257525 | The Hospital for Sick Children | N/A |
| Unknown | Thymosin α1 Use in Rheumatic Heart Disease Patients Undergoing Cardiac Surgery on Cardiopulmonary Bypass NCT05487469 | Nanjing Medical University | N/A |
| Completed | Relationship Between Perioperative Carotid Blood Flow Monitoring and Cerebral Function Protection in Cardiac S NCT05586347 | Nanjing First Hospital, Nanjing Medical University | N/A |
| Recruiting | Cardiopulmonary Bypass Induced Red Blood Cell Lysis NCT05189262 | University of Maryland, Baltimore | — |
| Completed | Soluble VE-cadherin in Prediction and Diagnosis of Early Postoperative Hypoxemia After Cardiopulmonary Bypass NCT05647382 | Zhuan Zhang | N/A |
| Completed | The Role of Dexmedetomidine As Myocardial Protection In Pediatric Cyanotic Congenital Heart Disease Undergoing NCT05300802 | National Cardiovascular Center Harapan Kita Hospital Indonesia | Phase 2 / Phase 3 |
| Unknown | Cerebral Monitor Guided Therapy on Cerebral Outcomes After Cardiac Surgery NCT03316183 | University of Washington | N/A |
| Completed | Methadone in Adults Undergoing Cardiac Surgery NCT05075265 | Pontificia Universidad Catolica de Chile | — |
| Completed | Dexmedetomidine and Myocardial Protection NCT04871308 | Seoul National University Hospital | N/A |
| Completed | Cardioplegic Protection of the Heart NCT07386990 | Region Skane | Phase 4 |
| Terminated | TEG 6s® for Perioperative Monitoring of Platelet Function During Cardiopulmonary Bypass for Cardiac Surgery NCT04746560 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Breethe Abiomed Recovery RegisTry (BART) NCT05473130 | Abiomed Inc. | — |
| Completed | AProtinin Versus Tranexamic Acid in Cardiac Surgery Patients With High-risk for Excessive Bleeding NCT04804345 | University Hospital, Bordeaux | — |
| Unknown | Endocan Blood Level in Pulmonary Circulation NCT04616820 | Centre Hospitalier Universitaire de Besancon | — |
| Completed | Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Pos NCT04452188 | University of Michigan | N/A |
| Completed | Role of Glutamine as Myocardial Protector in Elective On-Pump CABG Surgery With Low EF NCT04560309 | National Cardiovascular Center Harapan Kita Hospital Indonesia | Phase 3 |
| Completed | Mri characterIzation of Troponin Elevation After Cardiac Surgery NCT04490785 | Hospices Civils de Lyon | N/A |
| Completed | REnal TRansplant Outcomes After CARdiac Surgery (RETROCAR) NCT04979754 | University Hospital, Bordeaux | — |
| Completed | Norepinephrine Infusion During Cardiopulmonary Bypass NCT04312971 | Imam Abdulrahman Bin Faisal University | N/A |
| Completed | Heparin and Protamine Titration in Cardiac Surgery Under Minimal Invasive Extracorporeal Circulation NCT04215588 | Aristotle University Of Thessaloniki | N/A |
| Unknown | Prevalence of Auditory Dysfunction and ICU-acquired Delirium Following Cardiac Surgery With Cardiopulmonary By NCT04151914 | European Georges Pompidou Hospital | — |
| Completed | Impact of Cardiopulmonary Bypass Flow on Renal Oxygenation, Blood Flow and Tubular Injury NCT04084301 | Sahlgrenska University Hospital | N/A |
| Completed | Comparison of Remowell 2 and Inspire on Delirium and Cognitive Dysfunction NCT04062396 | Maria Cecilia Hospital | N/A |
| Unknown | Circulating Tumor Cells (CTC) Before and After Thoracic Resection With and Without Intraoperative Use of Extra NCT04048512 | European Institute of Oncology | — |
| Unknown | Integration of Minimal Invasive Cardiopulmonary Bypass System and the Research of Its Blood Compatibility NCT04476342 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Completed | Hyperosmolality and Acute Kidney Injury After Cardiac Surgery NCT05914896 | Umeå University | N/A |
| Active Not Recruiting | Low-dose Dexmedetomidine and Postoperative Delirium After Cardiac Surgery NCT03624595 | Dong-Xin Wang | N/A |
| Completed | Calcium Administration in Cardiac Surgery NCT03772990 | Meshalkin Research Institute of Pathology of Circulation | Phase 4 |
| Unknown | Hemoperfusion in Acute Type A Aortic Dissection Patients Undergoing Aortic Arch Operation (HPAO) NCT04007484 | The Second Hospital of Nanjing Medical University | N/A |
| Completed | Platelets and Complement Activation in Coronary Artery Bypass Graft Surgery (CABG) NCT05033236 | Medical University Innsbruck | — |
| Unknown | Oxygenation Targets in Cardiac Surgery Patients - a Before-and-after Study NCT04133740 | Aalborg University Hospital | Phase 4 |
| Unknown | Mechanical Ventilation During Cardiopulmonary Bypass NCT03629574 | Azienda Ospedaliera di Padova | N/A |
| Completed | Prediction of PPC Using DAMPs in Adult Cardiac Surgery NCT04945915 | Pusan National University Yangsan Hospital | — |
| Unknown | Multi-omics Study on Gut Microbiota in Critical Ill Patients After Cardiopulmonary Bypass NCT04032938 | Peking Union Medical College Hospital | — |
| Unknown | Thiamine Influenced on Substrate Energy Effectiveness in Indonesian Children Undergoing Cardiopulmonary Bypass NCT04453761 | National Cardiovascular Center Harapan Kita Hospital Indonesia | Phase 4 |
| Completed | Automated vs Conventional Perioperative Glycemic Control in Diabetic Patients Undergoing Cardiopulmonary Bypas NCT03314272 | American University of Beirut Medical Center | N/A |
| Completed | Intraoperative Use of Extracorporeal Cytokine Adsorption During Orthotopic Heart Transplantation NCT03145441 | Semmelweis University | N/A |
| Completed | Maintaining Mechanical Ventilation During Cardiopulmonary Bypass for Cardiac Surgery NCT03372174 | Rennes University Hospital | N/A |
| Completed | Protection During Cardiac Surgery. NCT03230136 | Hospices Civils de Lyon | N/A |
| Recruiting | Preventing Systemic Inflammation After Cardiac Surgery With Alkaline Phosphatase NCT03050476 | Alloksys Life Sciences B.V. | Phase 2 / Phase 3 |
| Completed | The Effect of Nitroglycerin Infusion Rate on Cerebral Rewarming During Hypothermic Coronary Artery Bypass Graf NCT03251599 | Recep Tayyip Erdogan University | Phase 4 |
| Completed | Prognostic Markers of Inflammation in Infants Undergoing Cardiopulmonary Bypass NCT03143348 | University of Oklahoma | — |
| Completed | Two Monitors for Measuring the Activated Clotting Time: A Comparison NCT03203148 | Umeå University | — |
| Completed | Platelet Transfusion During Neonatal Open Heart Surgery NCT03045068 | The University of Texas Health Science Center, Houston | Phase 4 |
| Completed | Changes in Plasma Osmolality Related to the Use of Cardiopulmonary Bypass With Hyperosmolar Prime. NCT03060824 | Umeå University | — |
| Unknown | Comparative Analysis Between Ringer's Lactate vs Plasma Lyte-A as Cardiopulmonary Bypass Prime NCT03043131 | Post Graduate Institute of Medical Education and Research, Chandigarh | Phase 3 |
| Completed | Acute Kidney Injury in Children After Cardiopulmonary Bypass NCT03144011 | Meshalkin Research Institute of Pathology of Circulation | — |
| Completed | Blood Isoflurane Concentration and the Oxygenator NCT03146949 | University of Edinburgh | N/A |
| Completed | Preoperative Dual Antiplatelet Therapy: Platelet Function and Influence of Cardiopulmonary Bypass NCT02979158 | Umeå University | N/A |
| Completed | Increased Adsorption Membranes During Cardiopulmonary Bypass NCT02518087 | Hospital Universitari de Bellvitge | N/A |
| Completed | Predictive and Prognostic Value of Cellular Dysoxia Markers After Cardiac Surgery With Extracorporeal Circulat NCT03107572 | University Hospital, Lille | — |
| Completed | Extracorporeal Cytokine Adsorption in Cardiac Surgery NCT02666703 | University Medical Centre Ljubljana | Phase 3 |
| Completed | Ulinastatin Improves Postoperative Oxygenation After Cardiopulmonary Bypass NCT03154814 | Konkuk University Medical Center | Phase 4 |
| Completed | Central and Peripheral Arterial Pressure Decoupling In Cardio-Pulmonary Bypass NCT02652858 | Hospices Civils de Lyon | N/A |
| Completed | Parameters of Cerebral Perfusion NCT02806492 | UMC Utrecht | N/A |
| Completed | Intraoperative Dexamethasone in Pediatric Cardiac Surgery NCT02615262 | Meshalkin Research Institute of Pathology of Circulation | Phase 3 |
| Completed | Heparin Based on Ideal Body Weight for Cardiopulmonary Bypass in Obese Patients NCT02675647 | University Hospital, Strasbourg, France | Phase 4 |
| Unknown | Postoperative Gastrointestinal Dysfunction After Cardiac Surgery - Occurrence and Search for Biomarkers NCT02732301 | Region Örebro County | — |
| Completed | Minto Model in Effect Site Mode for Target-Controlled Infusion of Remifentanil During Cardiopulmonary Bypass NCT02566733 | Seoul National University Hospital | Phase 4 |
| Recruiting | Optimal Cardiopulmonary Bypass and Anticoagulation Management Strategies in Obese Patients Undergoing Cardiac NCT03302195 | Laval University | N/A |
| Completed | Evaluation Of The Pharmacokinetics Of Antithrombin III In Neonates And Infants Undergoing CPB And ECMO Support NCT02631174 | Children's Hospital Medical Center, Cincinnati | Phase 1 |
| Completed | Nitric Oxide-mediated Cardioprotection During Cardiac Surgery With Cardiopulmonary Bypass NCT03500783 | Tomsk National Research Medical Center of the Russian Academy of Sciences | Phase 1 / Phase 2 |
| Completed | Hemosonics- VCU Cardiac Surgery Clinical Study NCT02392247 | Virginia Commonwealth University | — |
| Completed | Isoflurane During Cardiopulmonary Bypass NCT02471950 | University of Edinburgh | — |
| Completed | Clinical Trial to Evaluate the Use of an Adsorption Membrane (oXiris®) During Cardiopulmonary Bypass Surgery NCT02398019 | Hospital Universitari de Bellvitge | N/A |
| Completed | Prognostic Value of Peak Lactate During Cardiopulmonary Bypass in Adult Cardiac Surgeries NCT03934892 | Hualien Tzu Chi General Hospital | — |
| Completed | Lung Ultrasonography After Major Cardiac Surgery NCT03279887 | Groupe Hospitalier Pitie-Salpetriere | — |
| Completed | Safety and Efficacy of Preoperative Antithrombin Supplementation in Patients Undergoing High-Risk Cardiopulmon NCT02037555 | Grifols Therapeutics LLC | Phase 2 |
| Completed | Variations of the Lung Compliance During Extracorporeal Circulation and Post Operative Pulmonary Complications NCT02654600 | Centre Chirurgical Marie Lannelongue | — |
| Unknown | The Effect of Remote Ischemic Preconditioning in Aortic Valve Replacement Surgery NCT03305094 | Laval University | N/A |
| Completed | Pharmacokinetics of Dexmedetomidine in Children During Cardiopulmonary Bypass (CPB) NCT02059343 | Duke University | — |
| Completed | Desflurane,Brain Natriuretic Peptide and Cardiac Surgery NCT04238806 | Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital | N/A |
| Terminated | Cerebral Perfusion Monitoring With Transpharyngeal Ultrasonography NCT01828411 | Insel Gruppe AG, University Hospital Bern | — |
| Unknown | Effects of Ischemic Postconditioning on MicroRNAs in Double Valve Replacement NCT01804283 | Central South University | N/A |
| Completed | Colloids in Pediatric Cardiac Surgery: Comparison Between a Balanced and a Non-balanced Colloid NCT02584868 | Queen Fabiola Children's University Hospital | Phase 3 |
| Completed | Point of Care Testing in Pediatric Patients Undergoing Major Surgery NCT01742936 | Nationwide Children's Hospital | N/A |
| Completed | Procalcitonin and Postoperative Outcome After Open-heart Surgery NCT04213040 | Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital | — |
| Completed | Cefazolin Dosing in Children Undergoing Cardiac Surgery With Cardiopulmonary Bypass NCT02749981 | University Hospital, Ghent | — |
| Completed | Understanding "Heparin Resistance" in Cardiac Surgery NCT01598883 | Massachusetts General Hospital | Phase 1 |
| Terminated | The Effects of Anesthesia on Patients Undergoing Surgery for Repair of a Thoracoabdominal Aneurysm. NCT01772537 | Johns Hopkins University | N/A |
| Unknown | Benefits of GIK in Cardiac Surgery Patients NCT01516138 | Xijing Hospital | Phase 2 |
| Completed | Antithrombin Enhancement May Improve Anticoagulation Efficiency in Infants Undergoing Cardiopulmonary Bypass f NCT01530737 | The Hospital for Sick Children | Phase 3 |
| Unknown | Effect of Rewarming Rate During Cardiopulmonary Bypass on Clinical Prognosis of Infants Undergoing Cardiac Sur NCT01398709 | Xijing Hospital | Phase 2 |
| Completed | Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass NCT01228305 | Vanderbilt University Medical Center | N/A |
| Completed | Thrombin Generation in Neonatal Plasma After Cardiopulmonary Bypass NCT01352143 | Emory University | — |
| Completed | Seattle Cardiorenal Remote Ischemic Preconditioning Trial NCT01260259 | Seattle Children's Hospital | N/A |
| Completed | Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MDCO-2010 in Patients Undergoing Elective Coron NCT01535222 | The Medicines Company | Phase 2 |
| Unknown | Acupuncture Improves Sleep in Patients Undergoing Cardiopulmonary Bypass NCT01231776 | Xijing Hospital | N/A |
| Completed | Comparison of Tranexamic to Epsilon Aminocaproic Acid: a Prospective Analysis of Blood Conservation in Cardiac NCT01248104 | Loma Linda University | N/A |
| Completed | Cerebral Autoregulation Monitoring During Cardiac Surgery NCT00981474 | Northwestern University | N/A |
| Completed | Clinical Trial Comparing Heparin and Protamine Fixed and Titrated Doses in Cardiac Surgery With Cardiopulmonar NCT01267487 | SANE-Society of Anesthesiology | Phase 4 |
| Terminated | Effect of Preliminary Administration of Cyclosporine (Sandimmun ®) on Different Markers of Cardiac Ischaemia I NCT01002859 | University Hospital, Grenoble | Phase 2 |
| Terminated | The Effect Of Acadesine On Reducing Cardiovascular and Cerebrovascular Adverse Events In Coronary Artery Bypas NCT00872001 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Voluven® in Paediatric Patients NCT00860405 | Fresenius Kabi | Phase 4 |
| Completed | Dose-ranging Study of Two Doses of Tranexamic Acid During Cardiac Surgery NCT00809393 | Hopital Foch | Phase 4 |
| Terminated | Study of Albumin to Reduce Inflammation Following Surgery NCT00773110 | Imperial College London | Phase 2 |
| Completed | Fenoldopam and Splanchnic Perfusion During Cardiopulmonary Bypass NCT00747331 | IRCCS Policlinico S. Donato | Phase 4 |
| Terminated | Sodium Bicarbonate in Cardiac Surgery Study NCT00672334 | Austin Health | Phase 2 / Phase 3 |
| Withdrawn | Validation of Near Infrared Spectroscopy (NIRS) During Heart-Lung Bypass in Children NCT00745394 | University of Texas Southwestern Medical Center | — |
| Completed | Management of Bleeding Following Cardiopulmonary Bypass NCT00672516 | University of Minnesota | — |
| Completed | The Effect of Washing Red Blood Cells on Post Heart Surgery Blood Loss NCT00624611 | University of British Columbia | Phase 3 |
| Withdrawn | Pharmacokinetics and Pharmacodynamics of MTR105 in Hypotensive Cardiac Surgery Patients NCT00482287 | Meditor Pharmaceuticals Ltd. | Phase 2 |
| Withdrawn | Validation of Venous Cannulae Flow Ratings NCT00906906 | University of Texas Southwestern Medical Center | — |
| Completed | The Performance of Pulse Oximeters in Pediatric Patients With Low Oxygen Saturation Levels NCT00854048 | Ulf Borg | — |
| Unknown | Steroids In caRdiac Surgery Trial (SIRS Trial) NCT00427388 | Population Health Research Institute | Phase 4 |
| Completed | Plasma Gabapentin Concentration During and Following Cardiac Bypass NCT01022736 | Queen's University | Phase 4 |
| Completed | Aprotinin in Neonates Undergoing Cardiopulmonary Bypass NCT00469742 | Children's Healthcare of Atlanta | — |
| Completed | SPY Imaging System: Its Role in Pediatric Cardiac Surgery NCT00446927 | Emory University | — |
| Terminated | Cardiopulmonary Bypass-Induced Lymphocytopenia and the Potential Effects of Protease Inhibitor NCT00385450 | Mayo Clinic | Phase 1 |
| Completed | The RAS, Fibrinolysis and Cardiopulmonary Bypass NCT00607672 | Vanderbilt University | Phase 4 |
| Terminated | Sequestration of Platelets Prior to Bypass Reduces Bleeding After Cardiac Surgery NCT00359398 | Royal Brompton & Harefield NHS Foundation Trust | Phase 2 |
| Terminated | Use of Phenoxybenzamine [PBZ] IV to Assist High Flow Low Pressure Perfusion [HFLPP] on Cardio-pulmonary Bypass NCT00620945 | The Cleveland Clinic | N/A |
| Unknown | Does Sildenafil Protect Against Pulmonary Related Complications Following Cardiopulmonary Bypass? NCT00350441 | NHS Greater Glasgow Yorkhill Division | Phase 4 |
| Completed | Bradykinin Receptor Antagonism During Cardiopulmonary Bypass NCT00223704 | Vanderbilt University | Phase 2 / Phase 3 |
| Terminated | Nesiritide Use Following Cardiac Surgery in Infants NCT00281671 | Boston Children's Hospital | Phase 1 / Phase 2 |
| Completed | Glutamate and Diastolic Function in Patients Undergoing Aortic Valve Repair NCT01144039 | Medical University of Vienna | Phase 4 |
| Completed | Protection of the Heart With Doxycycline During Coronary Artery Bypass Grafting NCT00246740 | University of Alberta | Phase 2 |
| Suspended | Acetylcysteine Against Acute Renal Insult During Cardiopulmonary Bypass. NCT00190034 | Far Eastern Memorial Hospital | Phase 4 |
| Unknown | Cardiopulmonary Bypass (CPB) Pumps and Blood Activation NCT00187967 | University Hospital, Angers | N/A |
| Completed | Processed Residual Pump Blood in Cardiac Surgery: The PRBC Trial NCT01173822 | Hamilton Health Sciences Corporation | N/A |
| Completed | Safety and Effectiveness of the Medtronic Resting Heart Bypass System in Heart Surgery Patients NCT00303641 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Phase 1 |
| Terminated | The Use of HEMOBAG to Salvage Blood After Cardiac Surgery NCT00176657 | University of Medicine and Dentistry of New Jersey | Phase 2 |
| Completed | Clinical Study to Evaluate Nesiritide in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery A014 NCT00653042 | Scios, Inc. | Phase 2 |
| Completed | Cardiopulmonary Bypass and Inflammatory Response NCT00167349 | University of Pittsburgh | — |
| Completed | Safety and Hemostatic Efficacy of Fibrin Sealant Vapor Heated, Solvent/Detergent Treated (FS VH S/D) Compared NCT00161733 | Baxter Healthcare Corporation | Phase 3 |
| Completed | Intravenous Phenoxybenzamine Use in Pediatric Patients Undergoing Open-Heart Surgery NCT00569855 | University of Arkansas | Phase 2 |
| Completed | Long-Term Cognitive Decline After Coronary Artery Bypass Grafting: is Off-Pump Surgery Beneficial? NCT00189215 | UMC Utrecht | Phase 4 |
| Completed | Immunonutrition in Cardiac Surgery NCT00247793 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Completed | Propofol Pharmacokinetics and Pharmacodynamics During Cardiopulmonary Bypass NCT00622791 | University of Sao Paulo | — |
| Withdrawn | An Efficacy and Safety Study for Nesiritide in Heart Failure Patients With Reduced Kidney Function Undergoing NCT00530361 | Scios, Inc. | Phase 3 |
| Unknown | Pentastarch Use in Cardiac Surgery NCT00182377 | Hamilton Health Sciences Corporation | N/A |