| Completed | Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein C ASCVD, Elevated Cholesterol | Phase 3 | 2017-12-21 |
| Completed | Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subject Heterozygous Familial Hypercholesterolemia, Elevated Cholesterol | Phase 3 | 2017-11-28 |
| Completed | Inclisiran for Subjects With ASCVD or ASCVD-Risk Equivalents and Elevated Low-density Lipoprotein Cholesterol ASCVD, Risk Factor, Cardiovascular, Elevated Cholesterol | Phase 3 | 2017-11-01 |
| Completed | A Study of Inclisiran in Participants With Renal Impairment Compared to Participants With Normal Renal Functio Renal Impairment | Phase 1 | 2017-06-22 |
| Completed | Safety of Either a Single or Two Intravenous Doses of Orbactiv in Participants With Acute Bacterial Skin and S Skin Diseases, Bacterial | Phase 4 | 2017-01-24 |
| Completed | A Study of ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH) Homozygous Familial Hypercholesterolemia | Phase 2 | 2016-12-13 |
| Completed | Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Colonoscopy | Phase 2 | 2016-05-01 |
| Completed | Trial to Evaluate the Effect of ALN-PCSSC Treatment on Low Density Lipoprotein Cholesterol (LDL-C) Atherosclerotic Cardiovascular Disease, Familial Hypercholesterolemia, Diabetes | Phase 2 | 2016-01-01 |
| Completed | MDCO-216 Infusions Leading to Changes in Atherosclerosis: A Novel Therapy in Development to Improve Cardiovasc Acute Coronary Syndrome | Phase 1 / Phase 2 | 2015-12-03 |
| Completed | A Study to Evaluate the Safety of a Single Intravenous (IV) Dose of Orbactiv (Oritavancin) in Participants on Acute Bacterial Skin and Skin Structure Infection | Phase 4 | 2015-09-29 |
| Completed | Study to Evaluate the Safety, Tolerability and Pharmacokinetics of a New Formulation of Oritavancin in Healthy Healthy | Phase 1 | 2015-07-01 |
| Completed | Safety and Clinical Utility Study of SSEC Fentanyl 40 mcg for Acute Post-op Pain Management in Pediatric Parti Pain, Postoperative | Phase 3 | 2015-06-29 |
| Withdrawn | Association Between Patients' Perceptions of Success in Post-op Pain Management and Overall Experience With Ca Postoperative Pain | — | 2015-06-01 |
| Terminated | Bivalirudin Infusion for Ventricular Infarction Limitation Acute Myocardial Infarction | Phase 3 | 2014-12-19 |
| Withdrawn | Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF Dyspnea, Hypertension, Acute Heart Failure | Phase 3 | 2014-08-01 |
| Completed | Cangrelor to Clopidogrel or Prasugrel Transition Study Coronary Artery Disease (CAD) | Phase 2 | 2013-12-02 |
| Terminated | ENDOvascular Interventions With AngioMAX: The ENDOMAX Trial Peripheral Endovascular Interventions, Bleeding | Phase 3 | 2013-09-24 |
| Completed | Cangrelor Prasugrel Transition Study Coronary Artery Disease | Phase 2 | 2013-06-01 |
| Completed | Cangrelor Ticagrelor Transition Study Coronary Artery Disease | Phase 2 | 2013-01-01 |
| Completed | Open-label, Randomized Trial in Participants Undergoing TAVR to Determine Safety & Efficacy of Bivalirudin vs Severe Aortic Stenosis, Transcatheter Aortic Valve Replacement, Aortic Valve Replacement | Phase 3 | 2012-10-01 |
| Completed | Appraisal of MDCO-157 and Plavix® Pharmacokinetics and Pharmacodynamics in Healthy Volunteers With an Evaluati Pharmacokinetics and Pharmacodynamics in Healthy Volunteers | Phase 1 | 2012-09-01 |
| Terminated | Phase II Study to Compare MDCO-2010 vs Placebo and Tranexamic Acid in Patients Undergoing Cardiac Surgery Bleeding | Phase 2 | 2012-03-01 |
| Completed | Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MDCO-2010 in Patients Undergoing Elective Coron Coronary Artery Bypass Graft, Cardiopulmonary Bypass | Phase 2 | 2010-11-01 |
| Completed | A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coro Atherosclerosis, Percutaneous Coronary Intervention, Acute Coronary Syndrome | Phase 3 | 2010-09-01 |
| Completed | European Ambulance Acute Coronary Syndrome (ACS) Angiography Trial Acute Coronary Syndrome | Phase 3 | 2010-03-01 |
| Completed | Utilisation of Angiox® in European Practice Stable Angina (SA), NSTE-ACS (NSTEMI and UA), STEMI (STE-ACS) | — | 2009-05-01 |
| Completed | Clevidipine in the Treatment of Blood Pressure in Patients With Acute Heart Failure (PRONTO) Hypertension, Heart Failure | Phase 3 | 2008-12-01 |
| Completed | Clevidipine Bolus Administration in the Treatment of Hypertensive Patients Undergoing Cardiac Surgery (SPRINT) Hypertension | Phase 2 | 2008-11-01 |
| Completed | Maintenance of Platelet Inhibition With Cangrelor Acute Coronary Syndrome (ACS) | Phase 2 | 2008-10-01 |
| Withdrawn | Bivalirudin PCI Registry in Heparin Induced Thrombocytopenia/Heparin Induced Thrombocytopenia and Thrombosis S Heparin-Induced Thrombocytopenia, Heparin-induced Thrombocytopenia and Thrombosis Syndrome | Phase 4 | 2008-09-01 |
| Completed | Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE) Hypertension, Hemorrhage | Phase 3 | 2008-06-01 |
| Completed | Assess the Effect of Cangrelor at the Therapeutic Dose and a Supratherapeutic Dose Level on the QT/QTc Interva Healthy | Phase 1 | 2008-06-01 |
| Completed | Bivalirudin as a Procedural Anticoagulant in Pediatrics Cardiology | Phase 2 | 2007-08-01 |
| Terminated | Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition. Atherosclerosis, Acute Coronary Syndrome (ACS) | Phase 3 | 2006-09-01 |
| Completed | Clevidipine in the Treatment of Patients With Severe Hypertension (VELOCITY) Hypertension | Phase 3 | 2006-09-01 |
| Terminated | A Clinical Trial to Demonstrate the Efficacy of Cangrelor Myocardial Infarction (MI), Acute Coronary Syndromes (ACS) | Phase 3 | 2006-04-01 |
| Completed | Pharmacokinetics/Pharmacodynamics (PK/PD) of Cangrelor Healthy | Phase 1 | 2005-03-01 |
| Completed | Clevidipine in the Perioperative Treatment of Hypertension (ECLISPE-SNP) Hypertension | Phase 3 | 2004-06-01 |
| Completed | Clevidipine in the Postoperative Treatment of Hypertension (ECLIPSE-NIC) Hypertension | Phase 3 | 2004-05-01 |
| Completed | Clevidipine in the Perioperative Treatment of Hypertension (ECLIPSE-NTG) Hypertension | Phase 3 | 2004-04-01 |
| Completed | Comparing Angiomax to Heparin With Protamine in Patients Undergoing Cardiopulmonary Bypass (CPB) Cardiovascular Disease, Coronary Artery Bypass Surgery | Phase 3 | 2004-04-01 |
| Completed | Angiomax in Patients With HIT/HITTS Type II Undergoing CPB Cardiovascular Disease, Coronary Artery Bypass Surgery | Phase 3 | 2004-04-01 |
| Completed | Bivalirudin in Patients With Acute Myocardial Infarction (AMI) Undergoing Primary PCI Myocardial Infarction | Phase 3 | 2004-04-01 |
| Completed | Study of Clevidipine Assessing Its Preoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-1) Hypertension | Phase 3 | 2004-01-01 |
| Completed | Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-2) Hypertension | Phase 3 | 2003-12-01 |
| Completed | Angiomax in Patients With HIT/HITTS Type II Undergoing Off-Pump Coronary Artery Bypass Grafting (CABG) (CHOOSE Thrombocytopenia, Thrombosis, Cardiac Disease | Phase 3 | 2003-10-01 |
| Completed | Comparison of Angiomax Versus Heparin in Acute Coronary Syndromes (ACS) Unstable Angina, Myocardial Infarction, Acute Disease | Phase 3 | 2003-08-01 |
| Completed | Comparing Angiomax to Heparin With Protamine Reversal in Patients OPCAB Cardiac Surgery, Coronary Artery Bypass Surgery | Phase 3 | 2003-08-01 |
| Completed | Study Of Angiomax In Infants Under Six Months With Thrombosis Thrombosis | Phase 2 | 2002-08-01 |
| Completed | Anticoagulant Therapy With Bivalirudin in the Performance of Percutaneous Coronary Intervention in Patients Wi Heparin-Induced Thrombocytopenia, Thrombosis | Phase 3 | 1999-04-01 |