NCT00569855

Intravenous Phenoxybenzamine Use in Pediatric Patients Undergoing Open-Heart Surgery

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 785 (actual)
• Sponsor: University of Arkansas · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Cardiopulmonary bypass is done with a machine that does the work of the heart and lungs during open-heart surgery. This study is to determine if intravenous (i.v.) phenoxybenzamine is safe. This drug lowers the blood pressure, making it easier for the cardiopulmonary bypass machine to deliver blood and oxygen to all of the organs and tissues.

Conditions

• Open-heart Surgery
• Cardiopulmonary Bypass

Interventions

Type	Name	Description
DRUG	Phenoxybenzamine	0.125 to 1 mg/kg given i.v. over 15 to 45 minutes in preparation for cardiopulmonary bypass; may be continued at 0.125 mg/kg/day in ICU

Timeline

• Start date: 2001-02-01
• Primary completion: 2010-08-01
• Completion: 2010-08-01
• First posted: 2007-12-10
• Last updated: 2011-03-01
• Results posted: 2011-03-01

Locations

1 site across 1 country: United States