NCT02566733

Minto Model in Effect Site Mode for Target-Controlled Infusion of Remifentanil During Cardiopulmonary Bypass

Performance of the Minto Model in Effect Site Mode for Target Controlled Infusion of Remifentanil During Cardiopulmonary Bypass

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 56 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Target controlled infusion with remifentanil is widely used during cardiac surgery, wich is performed using the Minto model. It was derived from patients undergoing general surgery. However, pharmacokinetics of remifentanil can be changed during cardiopulmonary bypass. The investigators tested whether Minto model for target controlled infusion produces constant plasma remifentanil concentration during the cardiac surgery.

Conditions

• Anesthetics, Intravenous
• Pharmacology
• Anesthetics
• Cardiopulmonary Bypass

Interventions

Type	Name	Description
DRUG	Remiva	Target controlled infusion of remifentanil (generic drug, Remiva™)
DRUG	Ultiva	Target controlled infusion of remifentanil (brand-named drug, Ultiva™)

Timeline

• Start date: 2015-10-01
• Primary completion: 2016-06-01
• Completion: 2016-06-01
• First posted: 2015-10-02
• Last updated: 2016-10-19

Locations

1 site across 1 country: South Korea