| Not Yet Recruiting | A Prospective Evaluation of Clinical Outcomes in Acute Ischemic Stroke After Endovascular Treatment w/Doppler NCT07013396 | Virginia Commonwealth University | N/A |
| Not Yet Recruiting | Rescue Distal Thrombectomy in Treatment for Persistent Distal Occlusions NCT07533253 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Not Yet Recruiting | Glenzocimab in Anterior Stroke With Large Ischemic Core Eligible for Endovascular Therapy NCT06437431 | Fondation Ophtalmologique Adolphe de Rothschild | Phase 2 / Phase 3 |
| Not Yet Recruiting | Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis NCT07356284 | ProMedica Health System | Phase 3 |
| Not Yet Recruiting | Evaluation of iNstroke Aspiration Catheters for Thrombectomy: a Multi-center Prospective Study NCT07376447 | iVascular S.L.U. | N/A |
| Not Yet Recruiting | Efficacy and Safety of Human Urinary Kallidinogenase Combined With Reteplase Intravenous Thrombolysis in the T NCT07483281 | China-Japan Union Hospital | N/A |
| Recruiting | Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyon NCT07115940 | Amrou Sarraj | N/A |
| Not Yet Recruiting | Safety and Efficacy of Adjunctive GM1 to Mechanical Thrombectomy for Acute Anterior Circulation Large Vessel O NCT07519044 | Xuanwu Hospital, Beijing | Phase 4 |
| Not Yet Recruiting | Safety and Efficacy of J147 in Acute Ischemic Stroke NCT07430917 | Abrexa Pharmaceuticals, Inc. | Phase 2 |
| Not Yet Recruiting | The Feasibility and Safety of RK-4 Injection Bypassing Blood-brain Barrier in the Treatment of Acute Large Hem NCT07514949 | yilong Wang | N/A |
| Not Yet Recruiting | Anisodine Hydrobromide for Patients With Acute Ischemic Stroke Undergoing Endovascular Therapy (HEAL) NCT07513233 | Capital Medical University | Phase 1 |
| Not Yet Recruiting | A Study of TAK-755 in Adults With Acute Ischemic Stroke NCT07392450 | Takeda | Phase 2 |
| Not Yet Recruiting | Head Cooling in Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy (COOLHEAD-2b) NCT07526649 | Auckland City Hospital | N/A |
| Not Yet Recruiting | Observational Study to Assess the Safety of rhTNK-tPA (Mingfule®) vs. Rt-PA (Actilyse®) in Treating Acute Isch NCT07519889 | CSPC Mingfule Pharmaceutical (Guangzhou) Co., Ltd. | — |
| Not Yet Recruiting | Extended Time Window Intravenous Tenecteplase Thrombolysis Registry for Acute Ischemic Stroke NCT07536165 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | — |
| Not Yet Recruiting | Butylphthalide for Brain Edema After Endovascular Treatment NCT07528456 | Nanfang Hospital, Southern Medical University | Phase 4 |
| Not Yet Recruiting | Extended Time Window Intravenous Thrombolysis Registry for Acute Ischemic Stroke NCT07536074 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | — |
| Not Yet Recruiting | Safely Quenching Complement in Stroke Survivors NCT07495722 | Columbia University | Phase 1 |
| Completed | Anesthesia Technique and Outcomes in Mechanical Thrombectomy for Acute Ischemic Stroke NCT07422649 | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital | — |
| Not Yet Recruiting | CGM in Acute Ischemic Stroke NCT07510919 | Isala | N/A |
| Not Yet Recruiting | Unknown Time of Onset Stroke RePerfusIon Without Advanced Imaging NCT07475949 | First Affiliated Hospital of Guangxi Medical University | Phase 3 |
| Not Yet Recruiting | Intra-Arterial Tirofiban After Complete Recanalization for Acute Intracranial Large-Vessel Occlusion NCT07537933 | Shandong Provincial Hospital | Phase 3 |
| Not Yet Recruiting | Intravenous Tenecteplase in Very Old Patients With Acute Ischemic Stroke NCT07475936 | First Affiliated Hospital of Guangxi Medical University | — |
| Not Yet Recruiting | Efficacy and Safety of Intra-arterial Tenecteplase in Acute Ischemic Stroke Patients With Medium Vessel Occlus NCT07469293 | Southwest Hospital, China | Phase 3 |
| Completed | ATILA Project: Aspirin Versus Tirofiban in Endovascular Treatment for Patients With Acute Ischemic Stroke Due NCT05225961 | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | Phase 4 |
| Not Yet Recruiting | Eptifibatide for Extended Window Ischemic Stroke After Thrombolysis NCT07347626 | Xinqiao Hospital of Chongqing | Phase 3 |
| Not Yet Recruiting | Emergency Stroke Unit With NeuAngio-CT (ESU-ACT) NCT07456228 | Beijing Tiantan Hospital | — |
| Not Yet Recruiting | Evaluation of a Point-of-care Lateral Flow Assay in Glial Fibrillary Acidic Protein (GFAP) and D-dimer in Diag NCT07474675 | Boston Children's Hospital | — |
| Recruiting | Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acu NCT07404852 | Washington University School of Medicine | N/A |
| Recruiting | A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours Af NCT07361302 | Boehringer Ingelheim | Phase 3 |
| Recruiting | SUMMIT RISE Study of Acute Ischemic Stroke Patients NCT07436156 | Route 92 Medical, Inc. | Phase 4 |
| Recruiting | Telemedicine-supported Management for Acute Ischemic Stroke NCT07302971 | Capital Medical University | N/A |
| Not Yet Recruiting | Hyperbaric Oxygen After Stroke Thrombectomy: A Multicenter Randomized Trial on Safety and Efficacy NCT07049692 | Beijing Chao Yang Hospital | N/A |
| Withdrawn | REVascularization In Large VEssel Occlusion for Acute Ischemic Stroke NCT07216170 | Microvention-Terumo, Inc. | N/A |
| Not Yet Recruiting | Safety and Efficacy of Human Adipose-Derived Stem Cell Exosomes in Acute Ischemic Stroke NCT07398612 | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | Phase 1 / Phase 2 |
| Not Yet Recruiting | Intravenous rhPro-UK Before Stroke Thrombectomy in the Extended Time Window (BRIDGE-PUK EXTEND) NCT07389460 | First Affiliated Hospital Xi'an Jiaotong University | Phase 3 |
| Completed | Postmarket Study of Tarvos Microguidewire in Neurovascular Interventional Surgery NCT07500155 | Keuro MedTech | — |
| Not Yet Recruiting | The Correlation and Mechanistic Study of GGCX Gene With Prognosis in Acute Ischemic Stroke NCT07269288 | Peking University Aerospace Center Hospital | — |
| Recruiting | Tenecteplase Before Interhospital Transfer in Acute Basilar Artery Occlusion at 4.5 to 24 Hours NCT07203625 | Xuanwu Hospital, Beijing | Phase 4 |
| Not Yet Recruiting | Clinical Comprehensive Evaluation of Neuroprotective Drugs for Acute Ischemic Stroke NCT07260760 | Qianfoshan Hospital | — |
| Recruiting | Study to Assess the Efficacy and Safety of QHRD106 Injection in Acute Ischemic Stroke. NCT07396337 | Changzhou Qianhong Bio-pharma Co., Ltd. | Phase 2 |
| Recruiting | Thrombolysis in Early Acute Ischemic Stroke Trial-Blood Pressure Management NCT07279259 | Shanghai East Hospital | Phase 2 |
| Not Yet Recruiting | Intravenous Tirofiban After Bridging Therapy for Acute Stroke With Atherosclerotic Large Artery Occlusion NCT07335107 | Beijing Tiantan Hospital | Phase 3 |
| Recruiting | Tenecteplase Before Interhospital Transfer for EVT in Acute Anterior Circulation LVO at 4.5-24 Hours NCT07253181 | Xuanwu Hospital, Beijing | Phase 3 |
| Not Yet Recruiting | Safety and Preliminary Efficacy of Hibernation-Like Therapy (Chlorpromazine and Promethazine) in Patients With NCT07364344 | Ji Xunming,MD,PhD | N/A |
| Not Yet Recruiting | BALANCE Trial Domain Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632 NCT07318948 | Bo Wu | N/A |
| Not Yet Recruiting | Efficacy and Safety of Intravenous Thrombolysis in Branch Atheromatous Disease NCT07299994 | Sigmund Freud PrivatUniversitat | — |
| Recruiting | A Study of the Safety, Tolerability and Preliminary Efficacy of B2065 in Patients With Acute Ischemic Stroke. NCT07371624 | Tasly Pharmaceutical Group Co., Ltd | Phase 1 / Phase 2 |
| Recruiting | Intra-arterial Recombinant Human Tenecteplase Tissue-type Plasminogen Activator (rhTNK-tPA) Thrombolysis for A NCT07302854 | Xiang Luo | Phase 2 / Phase 3 |
| Recruiting | Efficacy and Safety of Home-based Structured Physical Exercise in Patients With Acute Ischemic Stroke NCT07271082 | Capital Medical University | N/A |
| Recruiting | Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Therapy -2 NCT07263308 | Capital Medical University | Phase 3 |
| Not Yet Recruiting | Construction and Evaluation of an Intelligent Decision System for Reperfusion Therapy in Acute Ischemic Stroke NCT07316049 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | Phase III Clinical Trial of SHPL-49 Injection in the Treatment of Acute Ischemic Stroke NCT07241520 | Shanghai Hutchison Pharmaceuticals Limited | Phase 3 |
| Recruiting | Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With NCT07263776 | Capital Medical University | Phase 3 |
| Not Yet Recruiting | Intravenous Tirofiban After Delayed Thrombolysis in Stroke NCT07111806 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Phase 3 |
| Withdrawn | Minocycline Efficacy in Improving Neurological Outcome of Patients Who Undergo Endovascular Revascularization NCT05367362 | State University of New York at Buffalo | Phase 2 |
| Recruiting | Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke With Occlusion of the M2 Segment o NCT07347665 | Hyogo Medical University | N/A |
| Recruiting | Phase III Clinical Trial of rhTNK-tPA in Treating Acute Ischemic Stroke With Extended Time Window. NCT07201688 | CSPC Mingfule Pharmaceutical (Guangzhou) Co., Ltd. | Phase 3 |
| Recruiting | Safety and Efficacy Evaluation of the iNstroke 4F Thromboaspiration Catheter in Patients With Acute Ischaemic NCT07357285 | iVascular S.L.U. | N/A |
| Recruiting | Efficacy and Safety of the KPCXM18 Injection in Patients With Acute Ischemic Stroke NCT07279493 | Kunming Pharmaceuticals, Inc. | Phase 2 |
| Recruiting | Intravenous Thrombolysis Combined With Tirofiban in Acute Ischemic Stroke NCT07290751 | Beijing Anzhen Hospital | Phase 4 |
| Recruiting | CHinese ischEmic Stroke Beyond 4.5 Hours With TeNecteplase Under Optimized Non-Contrast CT Selection NCT06994975 | Huashan Hospital | Phase 3 |
| Not Yet Recruiting | Effects of Cerebrospinal Fluid Drainage on Cerebral Hemodynamics NCT07056907 | University of Zurich | N/A |
| Not Yet Recruiting | Tenecteplase vs Medical Management in 4.5-24h LVO no Access to EVT NCT07168278 | The First Affiliated Hospital of University of Science and Technology of China | Phase 3 |
| Not Yet Recruiting | RK-4 Intracalvariosseous Injection in Treatment of Acute Large Hemispheric Infarction NCT07203521 | Fuzhou Neurodawn Rongkang Pharmaceutical Co., Ltd | Phase 2 |
| Recruiting | HRS-7450 Injection Phase II Clinical Trial for Acute Ischemic Stroke. NCT07233070 | Fujian Shengdi Pharmaceutical Co., Ltd. | Phase 2 |
| Completed | Sodium Sivelestat With Mechanical Thrombectomy for Acute Stroke: A Pilot Study NCT07196605 | Xuanwu Hospital, Beijing | N/A |
| Recruiting | OPtimizing REperfusion by Intra-Arterial ThRomboLysis as Adjunct to Endovascular Treatment for Medium Vessel O NCT07137832 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Phase 3 |
| Not Yet Recruiting | Randomized a Clinical Trial With Medical Device in Acute Ischemic Stroke NCT07113184 | Instituto de Investigación Marqués de Valdecilla | N/A |
| Recruiting | Urokinase for Thrombolysis in Acute Ischemic Stroke NCT07047326 | Capital Medical University | N/A |
| Recruiting | Evaluation of the CONDA Stent Retriever in Acute Ischemic Stroke NCT07174505 | Anaconda Biomed S.L. | N/A |
| Recruiting | A Clinical Trial of MT200605 for the Treatment of Acute Ischemic Stroke NCT07205328 | Shaanxi Micot Pharmaceutical Technology Co., Ltd. | Phase 2 |
| Not Yet Recruiting | Efficacy and Safety of Xinglou Chengqi Granule for Acute Ischemic Stroke NCT07163702 | Dongzhimen Hospital, Beijing | Phase 2 |
| Enrolling By Invitation | Intra-Arterial Tenecteplase Following Endovascular Thrombectomy for Large Vessel Occlusion Stroke NCT06781385 | Wake Forest University Health Sciences | Phase 2 |
| Not Yet Recruiting | RK-4 Intracalvariosseous Injection in Treatment of Acute Large Hemispheric Infarction NCT07166380 | Neurodawn Pharmaceutical Co., Ltd. | Phase 1 / Phase 2 |
| Enrolling By Invitation | Intra-arterial Selective Hypothermic Magnesium Sulfate Infusion in Combination With Endovascular Thrombectomy NCT07163299 | Capital Medical University | Phase 1 / Phase 2 |
| Not Yet Recruiting | PCSK9 Inhibitors in Acute Ischemic Stroke Patients Undergoing Endovascular Therapy NCT07174375 | Nanfang Hospital, Southern Medical University | Phase 2 / Phase 3 |
| Recruiting | Clopidogrel Plus Aspirin in Acute Ischemic Stroke Following Thrombectomy and/or Intravenous Thrombolysis (CoPr NCT06638151 | University of Alberta | Phase 2 |
| Not Yet Recruiting | An Application Provides Temperature-related Health Risk Warnings and Protective Recommendations on Stroke NCT07097428 | Xuanwu Hospital, Beijing | N/A |
| Not Yet Recruiting | An Application Provides Personalized Suggestions Based on Secondary Prevention Risk Factors to Stroke Patients NCT07098143 | Xuanwu Hospital, Beijing | N/A |
| Withdrawn | Safety, Performance of CEREGLIDE 92 Intermediate Catheter in Treatment of Acute Ischemic Stroke NCT06386289 | Cerenovus, Part of DePuy Synthes Products, Inc. | N/A |
| Recruiting | Angong Niuhuang Pills With Different Bovine Bezoar Formulation Sources in the Treatment of AIS NCT06883110 | Tongji Hospital | N/A |
| Not Yet Recruiting | An Application That Can Provide Early Warning of Temperature Health Risks and Give Protective Suggestions or P NCT06904664 | Xuanwu Hospital, Beijing | N/A |
| Not Yet Recruiting | Human Umbilical Cord Blood Infusion in Patients with Acute Ischemic Stroke (AIS) NCT06040476 | StemCyte, Inc. | Phase 2 |
| Recruiting | Endovascular Therapy Combined With Tirofiban for Intracranial Atherosclerotic Acute Ischemic Stroke NCT07026318 | Beijing Anzhen Hospital | N/A |
| Recruiting | Tenecteplase for Intravenous Stroke Thrombolysis in Recent DOAC Users NCT07092709 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Phase 3 |
| Recruiting | Remote Ischemic Conditioning for Acute Moderate Ischemic Stroke Due to Large Artery Atherosclerosis NCT06775782 | First Affiliated Hospital Xi'an Jiaotong University | N/A |
| Recruiting | Intra-arterial Methylprednisolone After Successful Endovascular Thrombectomy Anterior Circulation Large Vessel NCT07141303 | Tang-Du Hospital | Phase 3 |
| Not Yet Recruiting | Efficacy and Safety of Tenecteplase Intravenous Thrombolysis in Acute Posterior Circulation Ischemic Stroke Wi NCT07094763 | The First Affiliated Hospital of University of Science and Technology of China | N/A |
| Completed | Heparin for RAO Post-Transradial Angiography in AIS NCT07162064 | Xiang Luo | Phase 3 |
| Not Yet Recruiting | SLGT2i for Neuroprotection in Patients With Acute Ischemic Stroke NCT07105917 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 3 |
| Recruiting | Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke NCT05691244 | Pharmazz, Inc. | Phase 3 |
| Recruiting | Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke NCT06440707 | University of California, Los Angeles | Phase 2 |
| Active Not Recruiting | Efficacy of Rescue Stenting/Angioplasty After Failed Thrombectomy for Acute Large Intracranial Vascular Occlus NCT07026344 | Beijing Anzhen Hospital | N/A |
| Not Yet Recruiting | Longitudinal Cohort Study on Immune Thrombocytopenia Complicated With Acute Ischemic Stroke NCT07070193 | Peking University People's Hospital | — |
| Active Not Recruiting | Effect of Balloon Angioplasty vs Stenting Following Residual Stenosis After Endovascular Treatment of Intracra NCT07026331 | Beijing Anzhen Hospital | N/A |
| Not Yet Recruiting | Study Evaluating Toro 88 Super Bore Aspiration Catheter for Acute Ischemic Stroke NCT07089355 | Toro Neurovascular, Inc. | N/A |
| Recruiting | Using AI Systems to Optimize the Clinical Outcome of Stroke Patients NCT06828679 | Chinese University of Hong Kong | N/A |
| Not Yet Recruiting | A Feasibility Study for the DAISe EZ Thrombectomy Device - Pacific NCT06042335 | MIVI Neuroscience, Inc. | N/A |
| Not Yet Recruiting | Safety Of A Second Dose Of Tenecteplase In Selected Acute Ischemic Stroke Patients Not Responding To The First NCT06801054 | Memorial Hermann Health System | Phase 1 |
| Not Yet Recruiting | Efficacy of Semaglutide in Improving Neurological Outcomes After Endovascular Thrombectomy for Acute Ischemic NCT07030621 | RenJi Hospital | Phase 3 |
| Not Yet Recruiting | Safety and Efficacy of Remote Ischemic Conditioning in Patients With Acute Ischemic Stroke NCT03669653 | Yi Yang | N/A |
| Recruiting | Qingre Huatan Formula for the Prevention of Early Neurological Deterioration in Acute Ischemic Stroke NCT06857487 | Dongzhimen Hospital, Beijing | Phase 1 / Phase 2 |
| Recruiting | Role of EEG in Differentiation Between Ischemic and Hemorrhagic Stroke NCT06984965 | Assiut University | — |
| Not Yet Recruiting | Intra-Arterial Magnesium Therapy After Mechanical Thrombectomy in Acute Ischemic Stroke NCT06956521 | Baylor College of Medicine | Phase 1 |
| Completed | Hybernia Medical Post-Mechanical Thrombectomy Cerebral Cooling in Stroke NCT06634303 | Hybernia Medical | N/A |
| Recruiting | Precision Antiplatelet Therapy Guided by Platelet Aggregation Function in Patients With Acute Ischemic STROKE NCT06853535 | Sichuan Provincial People's Hospital | Phase 3 |
| Recruiting | Optimizing Reperfusion to Improve Outcomes and Neurologic Function NCT06990867 | Corxel Pharmaceuticals | Phase 2 / Phase 3 |
| Not Yet Recruiting | Safety and Efficacy Study of Levofloxacin Combined With Endovascular Thrombectomy for Acute Ischemic Stroke NCT05743101 | Yi Yang | N/A |
| Completed | LEG-UP Feasibility Study: Elevated Leg Positioning For Acute Moderate Ischemic Stroke NCT07483580 | Bonifacio C. Pedreogsa II | N/A |
| Recruiting | Cerebral Large Vessel Occlusion Stroke Multiomics Biosample Cohort NCT06963489 | First Affiliated Hospital of Wannan Medical College | — |
| Recruiting | Comparison of 5G-Mobile Stroke Unit With Standard EMS for Acute Ischemic Stroke NCT06943885 | Beijing Emergency Medical Center | N/A |
| Not Yet Recruiting | A Single Ascending Dose of HRS-4029 in Healthy Subjects NCT06905314 | Beijing Suncadia Pharmaceuticals Co., Ltd | Phase 1 |
| Not Yet Recruiting | Imaging and Serological Biomarkers of Autonomic Dysfunction After Ischemic Stroke NCT06740942 | Universitätsklinikum Hamburg-Eppendorf | — |
| Recruiting | Ali Pay Intelligent Navigation Applet-aided Pre-hospital Triage for Non-emergency Medical Service Patients Wit NCT06613074 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Not Yet Recruiting | Methylprednisolone With Endovascular Thrombectomy for Large Ischemic Stroke NCT06870448 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Phase 3 |
| Recruiting | Heart Evaluation of Acute Ischemic Stroke With Reperfusion Therapy NCT06882577 | Soochow University | — |
| Recruiting | The Pivotal Study of RapidPulseTM Aspiration System NCT06029491 | RapidPulse, Inc | N/A |
| Recruiting | Aleeto in Acute ISchemic Stroke：A RandomISed Controlled Clinical Trial NCT06759753 | Beijing Tiantan Hospital | Phase 2 |
| Recruiting | Thrombolysis in Factor Xa-inhibitors Trial NCT06878066 | Guri Hagberg | Phase 3 |
| Withdrawn | C-arm Cone Beam CTP Guided Cerebrovascular Interventions NCT05536895 | University of Wisconsin, Madison | N/A |
| Not Yet Recruiting | Intravenous Thrombosis and Patients with Prior Ischemic Stroke Within 3 Months NCT06841978 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 3 |
| Recruiting | Efficacy and Safety of Human Urinary Kallidinogenase for Acute Ischemic Stroke Patients Receiving Reperfusion NCT06848894 | Beijing Tiantan Hospital | N/A |
| Recruiting | Head Down Tilt 15° to Increase Collateral Flow in Acute Ischemic Stroke NCT06297863 | University of Milano Bicocca | Phase 2 |
| Not Yet Recruiting | Effectiveness of Ginkgo Diterpene Lactone Meglumine in Acute Ischemic Stroke NCT06861426 | Ying Gao | — |
| Not Yet Recruiting | Intravenous Thrombolysis in Acute Ischemic Stroke with Active Cancer NCT06841965 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 3 |
| Completed | Nicardipine vs. Labetalol NCT07277283 | Haseki Training and Research Hospital | Phase 4 |
| Not Yet Recruiting | CompARing Between CO2 Phenylephrine and Phenylephrine Only Treatment in Patients With proGrEssing Cerebral inf NCT06770426 | Yonsei University | Phase 3 |
| Not Yet Recruiting | Safety and Efficacy of Remote Ischemic Conditioning in Patients with Severe Stenosis or Occlusion of Anterior NCT06823128 | The First Affiliated Hospital of University of Science and Technology of China | N/A |
| Not Yet Recruiting | Glucagon-like Peptide 1 Receptor Agonist in Acute Large Vessel Occlusion Stroke After Endovascular Treatment NCT06788626 | Wei Hu | Phase 3 |
| Recruiting | Intravenous Thrombolysis and NOAC NCT06749834 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 3 |
| Recruiting | Plaque Imaging in Routine Care to Detect Intraplaque Hemorrhage NCT06749106 | Ludwig-Maximilians - University of Munich | — |
| Not Yet Recruiting | Intra-arterial Hypothermic Magnesium Sulfate Infusion in Combination with Endovascular Thrombectomy in Acute I NCT06760195 | Capital Medical University | EARLY_Phase 1 |
| Active Not Recruiting | An EFS to Evaluate the CGuard Prime™ Carotid Stent in Acute Ischemic Stroke NCT06447116 | Jacobs institute | N/A |
| Recruiting | Microvention AnEurysm & STroke Real-life Data cOllection NCT06494436 | Microvention-Terumo, Inc. | — |
| Recruiting | A Multicenter, Randomized Controlled Clinical Investigation to Evaluate the Safety and Effectiveness of the Su NCT06559475 | The First Affiliated Hospital of University of Science and Technology of China | N/A |
| Recruiting | PeRforation EVents During ENdovascular Therapy for Acute Ischemic Stroke NCT06394180 | University Hospital, Basel, Switzerland | — |
| Recruiting | To Assess the Effectiveness and Safety of Catheter-based Focal Intracranial Hypothermia Combined with Endovasc NCT06758609 | Guangdong Second Provincial General Hospital | N/A |
| Recruiting | Efficacy and Safety of Early Combined Therapy With PCSK9 Inhibitors and Statins in Acute Ischemic Stroke NCT06696820 | Xiang Luo | Phase 2 / Phase 3 |
| Recruiting | Multimodal Prognostic Assessment of Acute Ischemic Stroke Patients With Atrial Fibrillation: a Prospective, Mu NCT06548269 | Jinan Central Hospital | — |
| Recruiting | Safety and Efficacy Evaluation of the Ceretrieve Device in the Treatment of AIS Patients NCT06733246 | Ceretrieve Ltd. | N/A |
| Withdrawn | A Functional MRI Study: Assessing Brain Function in Post Stoke Patients NCT06573840 | NeuroGlove LLC | N/A |
| Recruiting | Study on Hibernation-like Therapy Based on Mechanical Thrombectomy NCT06663631 | Capital Medical University | Phase 1 |
| Recruiting | Early Antiplatelet Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT) NCT06548971 | Capital Medical University | Phase 3 |
| Not Yet Recruiting | The Intensive Care Bundle with Mortality Reduction in Acute Ischemic Stroke Trial NCT06628817 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Not Yet Recruiting | The Androtriol Injection for the Treatment of Acute Ischemic Stroke NCT06679322 | Beijing Tiantan Hospital | Phase 2 |
| Not Yet Recruiting | Safety and Efficacy of Edaravone Dexborneol for Acute Ischemic Stroke NCT06645522 | Yi Yang | Phase 4 |
| Recruiting | AI-Driven CTA Reconstruction for Intracranial LVO NCT06645405 | Shanghai Jiao Tong University Affiliated Sixth People's Hospital | N/A |
| Completed | Local Ischemic Postconditioning in Acute Ischemic Stroke NCT06526429 | Shanghai Jiao Tong University Affiliated Sixth People's Hospital | N/A |
| Recruiting | Radiohistological Correlation of Thrombohemorrhagic Remodeling in the Acute Phase of Ischemic Stroke Managed b NCT05847699 | Fondation Ophtalmologique Adolphe de Rothschild | N/A |
| Recruiting | Extending the Time Window for Intravenous Tenecteplase in Patients With Distal Medium Vessel Occlusions Stroke NCT06559436 | The First Affiliated Hospital of University of Science and Technology of China | N/A |
| Recruiting | NoNO-42 Trial in Acute Ischemic Stroke Patients Selected for Thrombolysis With or Without Endovascular Thrombe NCT06403267 | NoNO Inc. | Phase 2 |
| Recruiting | Outcome in Patients Treated With Endovascular Thrombectomy - optIMAL Blood Pressure Control 2 (OPTIMAL-BP 2) NCT06677970 | Yonsei University | Phase 3 |
| Recruiting | Remote Ischemic Conditioning for Acute Ischemic Stroke Treated With Mechanical Thrombectomy（RECAST-MT） NCT06559241 | Capital Medical University | Phase 3 |
| Recruiting | Basilar Artery Occlusion Chinese Endovascular Trial in the Extended Time Window NCT06560203 | Capital Medical University | N/A |
| Not Yet Recruiting | Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE NCT05293080 | Universitätsklinikum Hamburg-Eppendorf | Phase 3 |
| Completed | "The Effect of Trimetazidine on the Clinical Outcome of Acute Ischemic Stroke Patients" NCT06656442 | Ain Shams University | Phase 3 |
| Not Yet Recruiting | Endovascular Treatment for Stroke Post 1 Day （24 Hours） NCT06580730 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | N/A |
| Recruiting | Evaluation of Acute Endovascular Treatment in Symptomatic Isolated Cervical Internal Carotid Artery Occlusion NCT05832762 | University Hospital, Montpellier | N/A |
| Recruiting | MRSI Evaluation for Minor Stroke With Large Vessel Occlusion NCT06457217 | Shanghai 6th People's Hospital | — |
| Completed | Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Reperfusion Therapy NCT06538844 | Capital Medical University | Phase 2 |
| Recruiting | Efficacy and Safety of Calculus Bovis Sativus (CBS) for Ischemic Cerebral Vascular Disease (CBSinICVD) NCT06474507 | Tongji Hospital | N/A |
| Completed | Safety, Tolerability, and Preliminary Efficacy of HRS-7450 Injection in the Treatment of Acute Ischemic Stroke NCT06447415 | Fujian Shengdi Pharmaceutical Co., Ltd. | Phase 1 |
| Active Not Recruiting | Methylprednisolone Adjunctive to Endovascular Thrombectomy for Stroke NCT06360458 | Wan-Jin Chen | Phase 3 |
| Not Yet Recruiting | Umbilical Cord-derived Mesenchymal Stem Cell Infusion for Treating Acute Ischemic Stroke NCT06518902 | National Engineering Center of Cell Products | Phase 1 |
| Recruiting | Study of BB-031 in Acute Ischemic Stroke Patients (RAISE) NCT06226805 | Basking Biosciences, Inc. | Phase 2 |
| Completed | Efficacy and Safety of Early Initiation of Butylphthalide Treatment in Patients With Acute Ischemic Stroke. NCT06472921 | Xiangya Hospital of Central South University | Phase 2 |
| Completed | Study of the Effects of the Non-invasive Trigeminal Nerve Stimulation on Ischemic Stroke Patients NCT06540417 | Xidian University | N/A |
| Recruiting | Y-3 for Injection in the Treatment of Acute Ischemic Stroke NCT06517173 | Beijing Tiantan Hospital | Phase 3 |
| Recruiting | Blood Pressure Variability and Ischemic Stroke Outcome NCT05756257 | Yale University | — |
| Recruiting | Safety and Efficacy of Selective Intra-Arterial Cooling Infusion Combined With EVT in Acute Ischemic Stroke NCT06485427 | Beijing Shijitan Hospital, Capital Medical University | N/A |
| Recruiting | Predictive Role of sTREM in Endovascular Thrombectomy Outcomes NCT06545591 | The Affiliated Hospital of Xuzhou Medical University | — |
| Not Yet Recruiting | Quelling of Excitotoxicity in Acute Stroke With Ketamine NCT03223220 | Lower Merion Neurology Research Foundation | Phase 2 / Phase 3 |
| Recruiting | General Versus Regional Anesthesia for Carotid Endarterectomy at Acute Ischemic Stroke Trial NCT06175715 | Pirogov Russian National Research Medical University | N/A |
| Recruiting | The Effect of GD-iExo-003 in Acute Ischemic Stroke NCT06138210 | Xuanwu Hospital, Beijing | Phase 1 / Phase 2 |
| Not Yet Recruiting | Mechanical Thrombectomy of Acute Ischemic Stroke Anterior Circulation Distal Vessel Occlusion NCT06427187 | Assiut University | N/A |
| Recruiting | Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial NCT05611242 | Mercy Health Ohio | Phase 3 |
| Not Yet Recruiting | Exploring Cerebrolysin in Late Thrombectomy for Stroke: Blood-brain Barrier Biomarkers and Imaging Insights NCT06339411 | Chang Gung Memorial Hospital | EARLY_Phase 1 |
| Not Yet Recruiting | Virtual Intervention Stroke Initiative NCT05875389 | Ottawa Hospital Research Institute | N/A |
| Recruiting | Early Tirofiban Administration After Intravenous Thrombolysis in Acute Ischemic Stroke NCT06045156 | The First Hospital of Jilin University | N/A |
| Recruiting | Early Administration of Tirofiban in Patients Treated With Tenecteplase for Acute Ischemic Stroke NCT05604638 | Second Affiliated Hospital of Guangxi Medical University | Phase 3 |
| Completed | Safety Study of PP-007 in Subjects With Acute Ischemic Stroke NCT04677777 | Prolong Pharmaceuticals | Phase 1 |
| Recruiting | Efficacy and Safety of Human Urinary Kallidinogenase Combined With Endovascular Therapy in Acute Ischemic Stro NCT06211712 | Huashan Hospital | N/A |
| Completed | Tirofiban After Successful MT Recanalization in AIS NCT06265051 | Xiang Luo | Phase 2 / Phase 3 |
| Recruiting | Blood Biomarkers to Predict the Prognosis of a Stroke Patient Undergoing Mechanical Thrombectomy NCT06467396 | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | — |
| Completed | Early Feasibility Study of RapidPulseTM Aspiration System for Patients With Acute Ischemic Stroke NCT05899036 | RapidPulse, Inc | N/A |
| Recruiting | The Improve Acute Reperfusion Treatment Quality for Ischemic Stroke Through Spatiotemporal Computing in China NCT06330051 | Beijing Tiantan Hospital | N/A |
| Not Yet Recruiting | Safety and Efficacy of Urinary Kallidinogenase for Large Artery Atherosclerosis Acute Ischemic Stroke NCT06137300 | Yi Yang | N/A |
| Not Yet Recruiting | Effect of Ginkgo Biloba Extract on Cognitive Function in Acute Ischemic Stroke NCT06140888 | Yi Yang | N/A |
| Unknown | Rapid Local Ischemic Postconditioning in Acute Ischemic Stroke NCT06307743 | Shanghai Jiao Tong University Affiliated Sixth People's Hospital | N/A |
| Completed | Advancing Stroke Safety and Efficacy Through Early Tirofiban Administration After Intravenous Thrombolysis (AS NCT06134622 | The First Affiliated Hospital of University of Science and Technology of China | Phase 3 |
| Recruiting | Effect of Postoperative Prolonged Sedation With Dexmedetomidine After Successful Reperfusion With EVT on Long- NCT04916197 | Beijing Chao Yang Hospital | Phase 4 |
| Unknown | GD-11 for Injection in the Treatment of Acute Ischemic Stroke NCT06299579 | Beijing Tiantan Hospital | Phase 3 |
| Recruiting | Prognostic Prediction Model of Patients With AcUte Stroke undeRgoing EndOvascular TheRApy (AURORA) NCT06009315 | Beijing Tiantan Hospital | — |
| Recruiting | Neurocognitive Impairment After Ischemic Stroke NCT06262529 | Centre Hospitalier Universitaire de Nice | N/A |
| Recruiting | Endovascular Treatment for Mild Stroke With Acute Anterior Circulation Large Vessel Occlusion NCT06179017 | Zhangzhou Municipal Hospital | N/A |
| Unknown | BXOS110 Injection in the Treatment of Acute Ischaemic Stroke NCT06322394 | Biocells (Beijing) Biotech Co.,Ltd | Phase 2 |
| Unknown | Endovascular Therapy Versus Best Medical Treatment for Acute Large Vessel Occlusion Stroke With Low NIHSS NCT06143488 | First Affiliated Hospital of Wannan Medical College | N/A |
| Not Yet Recruiting | Cardiac CT Angiography in Patients With Acute Ischemic Stroke NCT06176872 | Universitätsklinikum Hamburg-Eppendorf | — |
| Recruiting | A Prospective Multicenter Registry Study on BASIS Technique for Endovascular Therapy of Acute Large Vessel Occ NCT06881420 | Fujian Medical University Union Hospital | — |
| Recruiting | Effect of Human Urinary Kallidinogenase on Inflammatory Factors in Acute Ischemic Stroke (KIF-AIS) NCT06696703 | First Affiliated Hospital of Harbin Medical University | N/A |
| Not Yet Recruiting | Efficacy and Safety of Urinary Kallidinogenase in the Treatment of Acute Ischemic Stroke Combined With Type 2 NCT06085378 | First Affiliated Hospital, Sun Yat-Sen University | N/A |
| Recruiting | Treatment of Acute Ischemic StroKe With Intravenous UroKinase Real-world Research: a Multicenter, Prospective NCT06194968 | The First Affiliated Hospital of Zhengzhou University | — |
| Completed | Safety and Efficacy of SHPL-49 Injection in Participants With Acute Ischemic Stroke NCT06202378 | Shanghai Hutchison Pharmaceuticals Limited | Phase 2 |
| Recruiting | UCMSCs as Treatment for Patients With Acute Ischemic Stroke (Stroke Neuroncell-EX) NCT06129175 | Cytopeutics Sdn. Bhd. | Phase 2 / Phase 3 |
| Not Yet Recruiting | Effects of Human Urinary Kallidinogenase on Early Improvement and Functional Outcomes in Acute Ischemic Stroke NCT06132880 | Beijing Tsinghua Chang Gung Hospital | N/A |
| Recruiting | Evaluation of Endovascular Treatment in Acute Intracranial Distal Medium Vessel Occlusion Stroke NCT06146790 | The First Affiliated Hospital of University of Science and Technology of China | N/A |
| Completed | Intracranial Distal Access Catheter in Neurointerventional Therapy NCT06989931 | MicroPort NeuroTech Co., Ltd. | — |
| Unknown | Short-term Effect of PCSK9 Inhibitor in Patients With Acute Ischemic Stroke NCT06134635 | Xuanwu Hospital, Beijing | — |
| Recruiting | Comparison of Perioperative Conscious Sedation During Endovascular Thrombectomy in Acute Ischemic Stroke NCT06139692 | Jinling Hospital, China | Phase 4 |
| Recruiting | Registration of Acute Ischemic Stroke With Large and Medium-sized Vascular Occlusion in Southwest China(LMVOS) NCT06125236 | Zhengzhou Yuan | — |
| Active Not Recruiting | Permanent Intracranial Stenting for Acute Ischemic Stroke Related to a Refractory Large Vessel Occlusion NCT06071091 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke NCT04918719 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Phase 2 |
| Recruiting | Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-2) NCT05789823 | Capital Medical University | Phase 2 |
| Unknown | Intra-arterial Albumin in Acute Ischemic Stroke After Endovascular Treatment for NCT06172387 | Tianjin Huanhu Hospital | Phase 1 |
| Unknown | EFfects of Y-6 SUblingual Tablets foR PaTients With AcUte Ischemic StRokE (FUTURE) NCT06138834 | Beijing Tiantan Hospital | Phase 2 |
| Completed | MRI-based Artificial Intelligence Software (NNS-SOT) for Onset Time Estimation in Lesion With Acute Ischemic S NCT06160726 | Nunaps Inc | — |
| Unknown | First-in-man Study of the Cerebrovascular Interventional Procedural Control System NCT05972252 | Hangzhou Dinova Neuroscience Technology Co., Ltd | N/A |
| Recruiting | Efficacy and Safety of Endovascular Recanalization for Acute Basilar Artery Occlusion With Extended Time Windo NCT06101667 | Beijing Tiantan Hospital | N/A |
| Completed | Millipede AspiRation for Revascularization in Stroke (MARRS) Study NCT05714501 | Perfuze | N/A |
| Unknown | A Prospective, Trial About Safety and Efficacy of Combined Treatment With Cerebrolysin in Acute Ischemic Hemis NCT06070753 | Shaare Zedek Medical Center | N/A |
| Unknown | Combination of Antiplatelet and Anticoagulation for AIS Patients Witn Concomitant NVAF and Extracranial/Intrac NCT06058130 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | Safety and Tolerability of Adjunctive TBO-309 in Reperfusion for Stroke NCT05363397 | The Florey Institute of Neuroscience and Mental Health | Phase 2 |
| Unknown | Early Versus Late Initiation of Anticoagulation in Mild-to-moderate AIS Patients With NVAF NCT06057467 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Unknown | Antiplatelet Therapy for AIS Patients With Thrombocytopenia NCT06053021 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Unknown | Adjunctive Use of Intra-Arterial TNK and Albumin Following Thrombectomy NCT06113848 | Tianjin Huanhu Hospital | Phase 3 |
| Unknown | Sodium Valproate in Patients With Acute Ischemic Stroke NCT06020898 | RenJi Hospital | Phase 2 |
| Completed | Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Acute Ische NCT05993884 | Allife Medical Science and Technology Co., Ltd. | Phase 1 |
| Unknown | Normobaric Hyperoxia Combined With Intravenous Thrombolysis for Acute Ischemic Stroke (OPENS-3) NCT05965687 | Ji Xunming,MD,PhD | Phase 3 |
| Unknown | Normobaric Hyperoxia Combined With Intravenous Thrombolysis for Acute Ischemic Stroke：Longterm Outcome (OPENS- NCT05965193 | Ji Xunming,MD,PhD | Phase 3 |
| Completed | Intra-arterial Thrombolysis After Successful Thrombectomy for Acute Ischemic Stroke in the Posterior Circulati NCT05897554 | Xuanwu Hospital, Beijing | N/A |
| Completed | PROMISE: PRedictors Of Good outcoMes in Thrombectomy for Large Infarct Core Stroke Evaluation NCT06016348 | 115 People's Hospital | — |
| Unknown | Radial Versus Femoral Access For Thrombectomy in Patients With Acute Basilar Artery Occlusion NCT05903560 | Jinling Hospital, China | N/A |
| Completed | The Extended CTA for the Successful Screening of Cardioaortic Thrombus in Acute Ischemic Stroke and TIA (DAYLI NCT05522244 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Active Not Recruiting | A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic NCT05953480 | Shionogi | Phase 2 |
| Not Yet Recruiting | High-Dose Atorvastatin for Vascular Wall Protection in Thrombectomy Patients NCT05912686 | Zhongda Hospital | Phase 4 |
| Unknown | Ultrasound for Acute Field Triage of Stroke NCT05845203 | University Hospital, Tours | N/A |
| Suspended | SY007 in Patients With Acute Ischemic Stroke NCT04891913 | Suzhou Yabao Pharmaceutical R&D Co., Ltd. | Phase 1 |
| Recruiting | Safety and Efficacy of Levofloxacin for Acute Ischemic Stroke NCT05799326 | Yi Yang | N/A |
| Completed | Comparison of Narcotrend and Cerebral Function Analysing Monitor in Intensive Care to Monitor Seizures and Dee NCT06067750 | Nottingham University Hospitals NHS Trust | — |
| Unknown | Effects of Remote Ischemic Conditioning on Cerebral Hemodynamics in Patients With Ischemic Stroke NCT05915832 | Yi Yang | N/A |
| Unknown | Cilostazol Dexborneol Versus Placebo for Microcirculation Dysfunction After Reperfusion Therapy in Patients Wi NCT05836766 | Beijing Tiantan Hospital | Phase 2 |
| Completed | Y-3 Injection in the Treatment of Acute Ischemic Stroke Phase II Clinical Trial NCT06429384 | Beijing Tiantan Hospital | Phase 2 |
| Completed | Intravenous Thrombolysis With rhTNK-tPA for Acute Non-large Vessel Occlusion in Extended Time Window NCT05752916 | Xuanwu Hospital, Beijing | Phase 4 |
| Recruiting | Safety and Efficacy of Levofloxacin Combined With Intravenous Thrombolysis for Acute Ischemic Stroke NCT05741905 | Yi Yang | N/A |
| Completed | AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation NCT06018545 | Oxford University Hospitals NHS Trust | — |
| Recruiting | Acute Ischemic Stroke EndoVascular Therapy: a Multicenter REGISTRY Study NCT05864638 | Changhai Hospital | — |
| Not Yet Recruiting | Association of Prophylactic Use of Stress Ulcer Drugs and Clinical Outcomes in Patients With Acute Anterior Ci NCT05845372 | Nanfang Hospital, Southern Medical University | — |
| Unknown | Multilevel System Intervention Based on Information Platform to Reduce Ischemic Stroke Recurrence Rate NCT05852080 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | Improving Low ASPECTS Stroke Thrombectomy NCT04862507 | Universitätsklinikum Hamburg-Eppendorf | — |
| Unknown | Single Ascending Dose Safety and Tolerability of NTS-104 Healthy Adults NCT05547438 | NeuroTrauma Sciences, LLC | Phase 1 |
| Recruiting | Efficacy and Safety of Head Acupuncture After Mechanical Thrombectomy for Acute Ischemic Stroke NCT05561088 | Xi'an No.3 Hospital | N/A |
| Completed | The Role of OXytocin in Acute Ischemic Stroke reconvAlesceNcE: The ROXANE Study NCT05873309 | University Hospital, Basel, Switzerland | — |
| Completed | Evaluate the Efficacy and Safety of TTYP01 Tablets in the Treatment of Acute Ischemic Stroke NCT06648304 | Shanghai Auzone Biological Technology Co., Ltd. | Phase 3 |
| Recruiting | Registry of Acute Ischemic Stroke With Large- or Medium-vessel Occlusion NCT05779215 | Xuanwu Hospital, Beijing | — |
| Completed | Feasibility Study of RapidPulseTM Aspiration System as Frontline Approach for Patients With Acute Ischemic Str NCT05577351 | RapidPulse, Inc | N/A |
| Completed | Early vs Delayed Extubation After Endovascular Treatment for Acute Ischemic Stroke NCT05847309 | Hospital Clinico Universitario de Santiago | N/A |
| Completed | Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke NCT05631847 | Sichuan Academy of Medical Sciences | N/A |
| Recruiting | Acute Subcutaneous SemaglutidE in Acute Ischemic sTroke NCT05630586 | Aarhus University Hospital | Phase 2 |
| Recruiting | Efficacy and Safety of LT3001 on Treating the Acute Ischemic Stroke NCT05686642 | Shanghai Pharmaceuticals Holding Co., Ltd | Phase 2 |
| Completed | Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-1b) NCT05909982 | Capital Medical University | Phase 1 / Phase 2 |
| Active Not Recruiting | Feasibility of a Digital Goals-of-Care Decision Aid for Clinicians and Families of Patients With SABI NCT05671874 | University of Massachusetts, Worcester | N/A |
| Unknown | Normobaric Hyperoxia Stabilizing Ischemic Penumbra NCT05781880 | Ji Xunming,MD,PhD | N/A |
| Unknown | A Research of Application of the New Model of Standardized Secondary Prevention of Stroke NCT05757635 | Peking Union Medical College Hospital | — |
| Completed | Study to Assess PK, Safety and Tolerability in Healthy Subjects NCT06380699 | Changzhou Qianhong Bio-pharma Co., Ltd. | Phase 1 |
| Completed | Guiding Catheters in Endovascular Stroke Therapy - Are Balloon Guided Catheters Superior? NCT07478042 | University Hospital Heidelberg | N/A |
| Withdrawn | Clinical Trial to Evaluate the Safety of Continuous IV Tirofiban in Acute Ischemic Stroke NCT04818944 | University of Iowa | Phase 1 / Phase 2 |
| Unknown | Study of the KPCXM18 Injection for Treatment of Acute Ischemic Stroke NCT05745311 | Kunming Pharmaceuticals, Inc. | Phase 2 |
| Terminated | Proximal TEmporary oCclusion Using Balloon Guide Catheter for Mechanical Thrombectomy NCT05592054 | Changhai Hospital | N/A |
| Unknown | Optimizing Door-to-reperfusion Times of One-stop Management in Acute Ischemic Stroke NCT05644938 | Can Tho Stroke International Services Hospital | N/A |
| Completed | The MRI-based Evaluation of Safety and Efficacy of EVT and SMT: A Retrospective, Multicenter Study NCT06236828 | Xuanwu Hospital, Beijing | — |
| Completed | rhPro-UK in Acute Ischaemic Stroke Within 4.5 Hours of Stroke Onset Trial 2(PROST-2) NCT05700591 | Tasly Biopharmaceuticals Co., Ltd. | Phase 3 |
| Completed | Intra-arterial TNK Following Endovascular Thrombectomy in Patients With Large Vessel Occlusion of Posterior Ci NCT05684172 | The First Affiliated Hospital of University of Science and Technology of China | Phase 2 / Phase 3 |
| Unknown | The Safety and Efficacy of Embotrap in Treating Acute Ischemic Stroke Patients NCT05667103 | Xuanwu Hospital, Beijing | N/A |
| Unknown | CERebrolysine Effect on Blood-brain Barrier in acUte Ischemic Stroke NCT06078215 | Poznan University of Medical Sciences | Phase 4 |
| Unknown | Effectiveness and Safety of Edaravone Dexborneol in Acute Ischemic Stroke NCT05644223 | Xuanwu Hospital, Beijing | — |
| Unknown | Zeit Alert for Stroke at Home (ZASH) Protocol NCT05669456 | Zeit Medical, Inc. | — |
| Not Yet Recruiting | Intracranial Hemorrhage Risk of Intensive Statin in Acute Ischemic Stroke With Cerebral Microbleeds NCT05589454 | Sichuan Provincial People's Hospital | Phase 4 |
| Completed | Efficacy and Safety Evaluation of the Thromboaspiration Catheter System iNstroke in Patients With Acute Ischem NCT05720975 | iVascular S.L.U. | — |
| Completed | Evaluate the Safety and Efficacy of Thrombectomy System in the Intravascular Treatment of Acute Ischemic Strok NCT05719688 | Suzhou Hengruihongyuan Medical Technology Co. LTD | N/A |
| Completed | Effect of Body Position on Hemodynamics in Patients With Acute Ischemic Stroke Undergoing Ultra-early Reperfus NCT05618535 | Yi Yang | N/A |
| Recruiting | Large Artery Occlusion Treated in Extended Time With Mechanical Thrombectomy Trial NCT05326932 | The George Institute for Global Health, China | N/A |
| Terminated | Evaluate Endovascular Treatment of Large Ischemic Stroke With Substantial Penumbra. NCT05539404 | University Hospital, Toulouse | N/A |
| Unknown | Hypothermia With Intrajugular Cooling in Acute Ischemic Stroke Thrombectomy NCT05488392 | Capital Medical University | N/A |
| Completed | Long-term Outcome of RIPC After IV Thrombolysis in AIS Patients NCT05614401 | First Affiliated Hospital Xi'an Jiaotong University | — |
| Unknown | Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-Ⅲ） NCT05745259 | Beijing Tiantan Hospital | Phase 3 |
| Unknown | sCLEC-2 in Stroke Study NCT05579405 | University of Yamanashi | — |
| Unknown | Prophylactic Effects of Agomelatine for Poststroke Depression NCT05426304 | First Affiliated Hospital, Sun Yat-Sen University | Phase 4 |
| Unknown | Effect of Serial Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation in Patients With Intravenous NCT05550103 | Yi Yang | N/A |
| Unknown | Dengzhanxixin Injection for Acute Ischemic Stroke Receiving Reperfusion Therapy NCT05700097 | Beijing Tiantan Hospital | Phase 2 |
| Completed | Neuromodulation Using Vagus Nerve Stimulation Following Ischemic Stroke as Therapeutic Adjunct NCT05390580 | Washington University School of Medicine | N/A |
| Unknown | A Study of XY03-EA Tablets in the Treatment of Acute Ischemic Stroke NCT05515393 | Shijiazhuang Yiling Pharmaceutical Co. Ltd | Phase 2 |
| Terminated | Validation of Velocity Curvature Index as a Diagnostic Biomarker Tool for Assessment of Large Vessel Stroke NCT05547412 | NovaSignal Corp. | — |
| Unknown | Impact of a Standardized Alarming System on Treatment Times and Workflow in Stroke Patients With Interhospital NCT05963685 | Munich Municipal Hospital | — |
| Unknown | Endovascular Treatment of Acute Ischemic Stroke With Underlying Intracranial Artery Stenosis NCT06260969 | Tianjin Huanhu Hospital | — |
| Completed | Cranial Ultrasound for Prehospital ICH Diagnosis NCT05492474 | Wake Forest University Health Sciences | N/A |
| Unknown | Comparison of Solitaire to Embotrap to Treat Large Vessel Occlusion in Acute Ischemic Stroke (SOLTRAP Study) NCT05518240 | WellStar Health System | — |
| Completed | A Study to Evaluate the Safety and Efficacy of Multiple Doses of LT3001 Drug Product in AIS Subjects NCT05403866 | Lumosa Therapeutics Co., Ltd. | Phase 2 |
| Completed | THUNDER: Acute Ischemic Stroke Study with the Penumbra System® Including Thunderbolt™ Aspiration Tubing NCT05437055 | Penumbra Inc. | N/A |
| Recruiting | A Study to Evaluate the Safety and Efficacy of LT3001 Drug Product in Subjects AIS Undergoing EVT NCT05198323 | Lumosa Therapeutics Co., Ltd. | Phase 2 |