NCT06176872

Cardiac CT Angiography in Patients With Acute Ischemic Stroke

Assessment of Cardiac CT Angiography in Patients Undergoing Thrombectomy for Ischemic Stroke

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 165 (estimated)
• Sponsor: Universitätsklinikum Hamburg-Eppendorf · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

Mortality rates after acute ischemic stroke remain high despite continuously improving treatment. In this context, it is important to note that a relevant portion of acute ischemic stroke patients die from adverse cardiovascular events, such as myocardial infarction, rather than from complications associated with the stroke itself. A possible reason might be that this patient group often suffers from at least moderate asymptomatic coronary artery disease. This study seeks to integrate cardiac computed tomography angiography into the standard-of-care diagnostic protocol of acute ischemic stroke. The aim of this prospective mono-centric trial is to enable accurate diagnosis of therapy-relevant coronary artery disease, other concomitant cardiac findings and cardiac causes of acute ischemic stroke, without delaying stroke therapy. In the long-run, the goal is to investigate whether cardiac computed tomography angiography and the resulting therapeutic measures (interventions or medications added) can improve functional outcome and rate of adverse cardiac complications in patients with acute ischemic stroke compared to a retrospective matched-cohort of patients without cardiac CT imaging.

Conditions

• Acute Ischemic Stroke
• Coronary Artery Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Cardiac Computed Tomography Angiography	Non-invasive imaging of the heart, the greater vessels and the coronary arteries using computed tomography.

Timeline

• Start date: 2024-01-01
• Primary completion: 2025-01-01
• Completion: 2027-01-01
• First posted: 2023-12-20
• Last updated: 2023-12-20