NCT06580730

Endovascular Treatment for Stroke Post 1 Day （24 Hours）

Endovascular Treatment Post 1 Day （24 Hours）: a Randomized Controlled Clinical Trial on Efficacy and Safety for Stroke

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 224 (estimated)
• Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Acute ischemic stroke (AIS) is one of the leading causes of disability and mortality worldwide. The treatment of this condition is time-critical, with the key to effective therapy being the early recanalization of the occluded vessel and restoration of blood flow to salvage the ischemic penumbra tissue. Currently, the time window for endovascular treatment in the anterior circulation can be extended up to 24 hours. Exploring endovascular treatments for patients beyond this time window (from 24 hours to 30 days) could mean hope for a greater number of AIS patients.

Conditions

• Acute Ischemic Stroke

Interventions

Type	Name	Description
PROCEDURE	Endovascular treatment	Endovascular intervention can be performed under either general anesthesia or conscious sedation based on best practices as determined by treating physician. Attempt should be made to expedite the transition from imaging to treatment in as rapid a fashion as possible. The subject should be prepared for the planned interventional procedure according to standard hospital procedures. Mechanical revascularization should be performed with the operators standard thrombectomy technique using aspiration or a stent retriever, separately or in combination.
OTHER	Standard medical treatment	Patients randomized to the control group will receive best conventional MT for acute ischemic stroke as determined by the attending stroke physician.

Timeline

• Start date: 2024-09-01
• Primary completion: 2026-08-01
• Completion: 2026-08-01
• First posted: 2024-08-30
• Last updated: 2024-09-05

Locations

1 site across 1 country: China