NCT07347665

Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke With Occlusion of the M2 Segment of Middle Cerebral Artery

Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke With Occlusion of the M2 Segment of Middle Cerebral Artery (the Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism-M2 Occlusion Trial: RESCUE-M2O Trial)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Hyogo Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 84 Years
• Healthy volunteers: Not accepted

Summary

RESCUE-M2O trial is a prospective, open label, blinded endpoint (PROBE), two-arm, randomized, controlled, post-market study to assess the efficacy and safety of endovascular therapy for acute ischemic stroke with occlusion of the M2 segment of the middle cerebral artery.

Conditions

• Endovascular Therapy
• Acute Ischemic Stroke
• Acute Ischemic Stroke (AIS) Related to a Distal Occlusion

Interventions

Type	Name	Description
PROCEDURE	Endovascular therapy	Endovascular therapy for acute ischemic stroke with occlusion of the M2 segment of the middle cerebral artery.

Timeline

• Start date: 2025-12-01
• Primary completion: 2028-03-31
• Completion: 2030-03-31
• First posted: 2026-01-16
• Last updated: 2026-02-24

Locations

2 sites across 1 country: Japan