| Recruiting | A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at Hi Respiratory Syncytial Virus Infections | Phase 2 | 2025-12-11 |
| Recruiting | Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disea Pompe Disease | Phase 2 | 2025-10-30 |
| Recruiting | A Study of S-892216-PO in Participants With Renal Impairment and Matched Controls Renal Impairment | Phase 1 | 2025-10-16 |
| Completed | Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls Hepatic Impairment | Phase 1 | 2025-08-30 |
| Completed | Study of BPN14770 in Participants With Severe Renal Impairment and Healthy Controls Renal Impairment | Phase 1 | 2025-08-25 |
| Recruiting | Study of S-892216 Long-acting Injectable (LAI) in Healthy Adult Participants Healthy Participants | Phase 1 | 2025-07-29 |
| Completed | A Study to Assess the Effects of BPN14770 on Rosuvastatin Healthy Participants | Phase 1 | 2025-07-18 |
| Completed | A Study of S-892216 in Participants With COVID-19 COVID-19 | Phase 2 | 2025-06-06 |
| Active Not Recruiting | Study of Zatolmilast (BPN14770) in Participants With PPP2R5D Neurodevelopmental Disorder (Jordan's Syndrome [J Jordan's Syndrome, PPP2R5D Neurodevelopmental Disorder | Phase 2 | 2025-05-13 |
| Completed | A Drug-Drug Interaction Study of S-217622 With Combined Oral Contraceptives in Healthy Adult Female Participan Healthy Adult Female Participants | Phase 1 | 2024-12-30 |
| Completed | A Drug-drug Interaction Study of S-892216 Coadministered With Carbamazepime to Healthy Adult Participants COVID-19 | Phase 1 | 2024-12-17 |
| Completed | A Study to Investigate How Respiratory Syncytial Virus (RSV) Infection Develops and Changes Over Time in Pedia RSV Infections | — | 2024-12-09 |
| Completed | A Study of S-740792 in Healthy Adult Study Participants Healthy Participants | Phase 1 | 2024-11-21 |
| Completed | A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and I Gram-Negative Bacterial Infections | Phase 2 | 2024-03-14 |
| Completed | A Study to Investigate Different Formulations of S-337395 in Healthy Adult Participants Healthy Volunteers | Phase 1 | 2024-03-13 |
| Completed | Effect of Administration of Itraconazole on the Pharmacokinetics of S-309309 in Healthy Participants Obesity, Healthy Volunteers | Phase 1 | 2023-11-15 |
| Active Not Recruiting | A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Acute Ischemic Stroke | Phase 2 | 2023-07-14 |
| Completed | Safety and Efficacy Study of S-309309 in Obese Adults Obesity | Phase 2 | 2023-06-21 |
| Completed | Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection SARS-CoV-2 Infection | Phase 3 | 2023-06-09 |
| Recruiting | Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids Opioid-Induced Constipation (OIC) | Phase 1 / Phase 2 | 2023-01-04 |
| Completed | A Study to Assess S-217622 in Participants With Mild and Moderate Hepatic Impairment and Healthy Control Parti Hepatic Impairment | Phase 1 | 2022-09-13 |
| Completed | A Study to Assess S-217622 in Participants With Renal Impairment and Healthy Participants Renal Impairment | Phase 1 | 2022-08-10 |
| Completed | A Study to Compare S-217622 With Placebo in Non-Hospitalized Participants With COVID-19 SARS-CoV-2 Infection | Phase 3 | 2022-08-03 |
| Completed | Use of Cefiderocol in the Management of Gram-Negative Infections Gram-Negative Infection | — | 2022-07-31 |
| Recruiting | S-531011 as Monotherapy and in Combination With an Immune Checkpoint Inhibitor in Advanced or Metastatic Solid Solid Tumors | Phase 1 / Phase 2 | 2022-05-30 |
| Completed | A Study to Assess the Effect of Cefiderocol on the Pharmacokinetics (PK) of Midazolam in Healthy Participants Healthy Volunteers | Phase 1 | 2022-05-24 |
| Completed | A Study to Assess S-309309 in Healthy and Obese Participants Obesity | Phase 1 | 2022-01-04 |
| Completed | A Study of S-268019 for the Prevention of COVID-19 SARS-CoV-2 | Phase 3 | 2021-12-25 |
| Completed | Study in Healthy Adults to Quantify Lung Deposition and Distribution of Radio-labelled S-770108 Inhalation Pow Healthy Volunteer | Phase 1 | 2020-11-09 |
| Terminated | A Study of Naldemedine in Participants Undergoing Surgeries That Include a Bowel Resection or Bowel Transectio Postoperative Gastrointestinal Dysfunction | Phase 2 | 2020-11-06 |
| Completed | A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol i Gram-negative Bacterial Infections, Bloodstream Infections (BSI), Complicated Intra-abdominal Infection (cIAI) | Phase 2 | 2020-08-21 |
| Completed | Women's Satisfaction and Adherence to Vulvovaginal Atrophy Treatments Vulvovaginal Atrophy | — | 2020-07-07 |
| Completed | A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Part Gram-negative Bacterial Infections, Hospital Acquired Bacterial Pneumonia (HABP), Complicated Urinary Tract Infection (cUTI) | Phase 2 | 2020-02-19 |
| Completed | Evaluation of S-600918 in Adults With Refractory Chronic Cough Chronic Cough | Phase 2 | 2020-02-13 |
| Completed | Evaluation of Safety, Tolerability, Pharmacokinetics, Drug-Drug and Food Interactions of Single and Multiple D Healthy Volunteer | Phase 1 | 2019-10-09 |
| Completed | First-in-human Study of S-588210 (S-488210+S-488211) Lung Cancer, Head and Neck Cancer, Bladder Cancer | Phase 1 | 2019-07-30 |
| Terminated | Cefiderocol Concentrations in the Lungs of Hospitalized Patients With Bacterial Pneumonia Bacterial Pneumonia | Phase 1 | 2019-02-20 |
| Terminated | A Study of Duloxetine (LY248686) in the Treatment of Japanese Children and Adolescents With Depressive Disorde Depressive Disorder | Phase 3 | 2018-01-29 |
| Completed | A Study of Duloxetine (LY248686) in Japanese Children and Adolescents With Depressive Disorder Depressive Disorder | Phase 3 | 2017-12-04 |
| Completed | Clinical Study of Cefiderocol (S-649266) for the Treatment of Nosocomial Pneumonia Caused by Gram-negative Pat Healthcare-associated Pneumonia (HCAP), Hospital Acquired Pneumonia (HAP), Ventilator Associated Pneumonia (VAP) | Phase 3 | 2017-10-24 |
| Completed | Study of S-033188 (Baloxavir Marboxil) Compared With Placebo or Oseltamivir in Patients With Influenza at High Influenza | Phase 3 | 2017-01-11 |
| Completed | A Study of S-033188 (Baloxavir Marboxil) Compared With Placebo or Oseltamivir in Otherwise Healthy Patients Wi Influenza | Phase 3 | 2016-12-08 |
| Completed | Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Car Healthcare-associated Pneumonia (HCAP), Bloodstream Infections (BSI), Hospital Acquired Pneumonia (HAP) | Phase 3 | 2016-09-07 |
| Completed | Study to Evaluate Ospemifene in Patients With Moderate to Severe Vaginal Dryness Due to Menopause Vaginal Dryness | Phase 3 | 2016-01-26 |
| Completed | Safety and Efficacy Study of Lusutrombopag for Thrombocytopenia in Patients With Chronic Liver Disease Undergo Chronic Liver Disease, Thrombocytopenia | Phase 3 | 2015-06-15 |
| Completed | A Study of Efficacy and Safety of Intravenous Cefiderocol (S-649266) Versus Imipenem/Cilastatin in Complicated Urinary Tract Infections | Phase 2 | 2015-02-05 |
| Completed | Efficacy and Safety of Naldemedine in Treating Opioid-induced Constipation Opioid-induced Constipation | Phase 3 | 2013-11-04 |
| Completed | Long Term Safety of Naldemedine Opioid-induced Constipation | Phase 3 | 2013-09-24 |
| Completed | Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation Opioid-induced Constipation | Phase 3 | 2013-08-29 |
| Completed | Combination Study Of S-555739/Cetirizine HCl In Adult Patients With Seasonal Allergic Rhinitis Seasonal Allergic Rhinitis | Phase 2 | 2012-07-01 |
| Completed | A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignan Opioid-induced Constipation | Phase 2 | 2011-08-17 |
| Completed | Safety and Efficacy of S-707106 in Subjects With Type 2 Diabetes Mellitus and Inadequate Glycemic Control With Type 2 Diabetes Mellitus | Phase 2 | 2010-10-01 |
| Completed | Study to Assess Safety and Pharmacokinetics of Double-Blind S-707106 Alone and in Combination With Open-Label Type 2 Diabetes Mellitus | Phase 1 | 2010-06-01 |
| Completed | Study to Evaluate the Safety and Efficacy of Naldemedine (S-297995) for the Treatment of Opioid-Induced Bowel Opioid Induced Bowel Dysfunction | Phase 2 | 2010-05-19 |
| Terminated | An Open-label Safety Study of Lusutrombopag (S-888711) in Adults With Chronic Immune Thrombocytopenia (ITP) Immune Thrombocytopenia | Phase 2 | 2010-04-29 |
| Completed | Double-Blind, Multi-Center, Randomized Study to Assess the Efficacy and Safety of Velneperit (S-2367) and Orli Obesity | Phase 2 | 2010-04-01 |
| Terminated | A Study to Investigate the Efficacy and Safety of Lusutrombopag (S-888711) Tablets Administered to Adults With Immune Thrombocytopenia (ITP) | Phase 2 | 2010-03-18 |
| Completed | Effect of Food and Calcium on Pharmacokinetics of a Single Dose of S-888711 in Healthy Adult Volunteers Healthy Volunteer | Phase 1 | 2009-11-06 |
| Completed | Open-Label Extension (OLE) Study for Safety and Efficacy of Velneperit (S-2367) in Obese Subjects Obesity | Phase 2 | 2008-08-01 |
| Completed | Efficacy and Safety of Ospemifene in the Treatment of Moderate to Severe Vaginal Dryness and Vaginal Pain Asso Atrophy, Vaginal Diseases | Phase 3 | 2008-07-01 |
| Completed | A Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With A Atopic Dermatitis | Phase 2 | 2008-05-01 |
| Completed | Open-Label, Chronic Exposure, Safety Study of CLONICEL (Clonidine HCl Sustained Release) in Children and Adole Attention Deficit Hyperactivity Disorder | Phase 3 | 2008-01-01 |
| Completed | A Clinical Study to Evaluate the Safety of Ospemifene Atrophy, Vaginal Diseases | Phase 3 | 2007-10-01 |
| Completed | A Clinical Study to Evaluate the Efficacy and Safety of Ospemifene in the Treatment of Vulvar and Vaginal Atro Atrophy, Vaginal Diseases | Phase 2 | 2007-08-01 |
| Completed | A Phase Ib/IIa, Double-Blind, Randomized Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharm Atopic Dermatitis | Phase 1 / Phase 2 | 2007-07-01 |
| Completed | Phase IIb One Year Efficacy and Safety Study of S-2367 in Obese Subjects With Initial 6-Week Low Calorie Diet Obesity | Phase 2 | 2007-06-01 |
| Completed | Phase IIb One Year Efficacy and Safety Study of S-2367 in Obese Subjects With Reduced Calorie Diet Obesity | Phase 2 | 2007-06-01 |
| Completed | A Study to Evaluate Daily Pravastatin, Fenofibrate or Pravafen in the Treatment of Combined Hyperlipidemia Combined Hyperlipidemia | Phase 3 | 2007-04-01 |
| Completed | Safety and Efficacy Study of Oral Glycopyrrolate Liquid for the Treatment of Pathologic (Chronic Moderate to S Cerebral Palsy, Neurological Conditions, Mental Retardation | Phase 3 | 2007-03-01 |
| Completed | Long-Term Safety of 30 mg and 60 mg Oral Daily Dose of Ospemifene in the Treatment of Vulvar and Vaginal Atrop Atrophy, Vaginal Diseases | Phase 3 | 2006-05-16 |
| Completed | Long-Term Safety of Ospemifene 60 mg Oral Daily Dose for the Treatment of Vulvar and Vaginal Atrophy (VVA) in Atrophy, Vaginal Diseases | Phase 3 | 2006-05-08 |
| Completed | A Clinical Study to Evaluate Ospemifene in the Treatment of Vulvar and Vaginal Atrophy in Postmenopausal Women Atrophy, Vaginal Diseases | Phase 3 | 2006-01-01 |
| Completed | Study of S-3304 in Patients With Locally Advanced Non-Small Cell Lung Cancer Non Small Cell Lung Cancer, Lung Cancer, Stage IIIA Non Small Cell Lung Cancer | Phase 1 / Phase 2 | 2003-02-01 |
| Completed | A Phase 1 Study of S-3304 in Patients With Solid Tumors Solid Tumors | Phase 1 | 2001-11-01 |
| Approved For Marketing | Expanded Access to Cefiderocol for the Intravenous Treatment of Severe Gram Negative Bacterial Infections Bacterial Infections | — | — |