Clinical Trials Directory

Trials / Completed

CompletedNCT02949011

Study of S-033188 (Baloxavir Marboxil) Compared With Placebo or Oseltamivir in Patients With Influenza at High Risk of Influenza Complications

A Phase 3, Multicenter, Randomized, Double-blind Study of a Single Dose of S-033188 Compared With Placebo or Oseltamivir 75 mg Twice Daily for 5 Days in Patients With Influenza at High Risk of Influenza Complications

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
2,184 (actual)
Sponsor
Shionogi · Industry
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

The primary objective of this study is to evaluate the efficacy of a single, oral dose of baloxavir marboxil compared with placebo by measuring the time to improvement of influenza symptoms in patients with influenza presenting within 48 hours of symptom onset.

Conditions

Interventions

TypeNameDescription
DRUGBaloxavir MarboxilTablets taken orally
DRUGPlacebo to Baloxavir MarboxilMatching tablets taken orally
DRUGOseltamivirCapsules taken orally
DRUGPlacebo to OseltamivirMatching placebo capsules taken orally

Timeline

Start date
2017-01-11
Primary completion
2018-04-12
Completion
2018-04-20
First posted
2016-10-31
Last updated
2019-11-19
Results posted
2019-11-06

Source: ClinicalTrials.gov record NCT02949011. Inclusion in this directory is not an endorsement.